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441por Bots, Selas T.F., Kemp, Vera, Cramer, Steve J., van den Wollenberg, Diana J.M., Hornsveld, Marten, Lamfers, Martine L.M., van der Pluijm, Gabri, Hoeben, Rob C.“…As a proof-of-concept, the Rb-binding domain of the E1A protein of the gorilla-derived HAdV-B nhpAd-lumc007 was deleted, thereby creating a new oncolytic derivative, which demonstrated increased oncolytic potential compared to HAdV-C5. …”
Publicado 2022
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442por Köster, Pamela C., Lapuente, Juan, Cruz, Israel, Carmena, David, Ponce-Gordo, Francisco“…SIMPLE SUMMARY: Human-driven activities, including agriculture, forestry, and mining, are destroying the natural habitats of wild great ape (bonobo, chimpanzee, gorilla, and orangutan) populations in Africa and Southeast Asia. …”
Publicado 2022
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443por Agrati, Chiara, Castilletti, Concetta, Battella, Simone, Cimini, Eleonora, Matusali, Giulia, Sommella, Andrea, Sacchi, Alessandra, Colavita, Francesca, Contino, Alessandra M., Bordoni, Veronica, Meschi, Silvia, Gramigna, Giulia, Barra, Federica, Grassi, Germana, Bordi, Licia, Lapa, Daniele, Notari, Stefania, Casetti, Rita, Bettini, Aurora, Francalancia, Massimo, Ciufoli, Federica, Vergori, Alessandra, Vita, Serena, Gentile, Michela, Raggioli, Angelo, Plazzi, Maria M., Bacchieri, Antonella, Nicastri, Emanuele, Antinori, Andrea, Milleri, Stefano, Lanini, Simone, Colloca, Stefano, Girardi, Enrico, Camerini, Roberto, Ippolito, Giuseppe, Vaia, Francesco, Folgori, Antonella, Capone, Stefania“…We report here on the kinetics of Spike-specific humoral and T-cell response in young and old volunteers over 6 months follow-up after a single intramuscular administration of GRAd-COV2, a gorilla adenoviral vector-based vaccine candidate currently in phase-2 of clinical development. …”
Publicado 2022
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444Publicado 2006Tabla de Contenidos: “…Rodman -- Variability of the feeding ecology of eastern gorillas / Martha M. Robbins, John Bosco Nkurunungi and Alastair McNeilage -- Sympatric western gorilla and mangabey diet : re-examination of ape and monkey foraging strategies / Diane M. …”
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445por Kirsch, Stefan, Pasantes, Juanjo, Wolf, Andreas, Bogdanova, Nadia, Münch, Claudia, Pennekamp, Petra, Krawczak, Michael, Dworniczak, Bernd, Schempp, Werner“…Duplicative transposition of the PKD1 gene and further amplification and evolution of the PKD1 pseudogenes may have arisen in a common ancestor of Homo, Pan and Gorilla ~8 MYA. Reticulate evolutionary processes such as gene conversion and non-allelic homologous recombination (NAHR) may have resulted in concerted evolution of PKD1 family members in human and chimpanzee and, thus, simulate an independent evolution of the PKD1 pseudogenes from their master PKD1 genes in human and chimpanzee.…”
Publicado 2008
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446por Ouyang, Mao, Li, Yongxin, Ye, Sheng, Ma, Jieyi, Lu, Liming, Lv, Weiming, Chang, Guangqi, Li, Xiaoxi, Li, Qing, Wang, Shenming, Wang, Wenjian“…We used starBase 2.1 and GOrilla to predict the potential targets of the specific miRNAs. …”
Publicado 2014
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447por Zamani, Neda, Sundström, Görel, Meadows, Jennifer RS, Höppner, Marc P, Dainat, Jacques, Lantz, Henrik, Haas, Brian J, Grabherr, Manfred G“…Not limited to protein coding genes, Kraken also identifies thousands of newly identified transcribed loci, likely non-coding RNAs that are consistently transcribed in human, chimpanzee and gorilla, and maintain significant correlation of expression levels across species. …”
Publicado 2014
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448“…However, our interpair optimization was not effective for the comparison of the sequences of different species such as comparing human, chimpanzee, and gorilla. Consequently, our method is useful in accelerating the applications that require optimal local alignments scores for the same species. …”
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449por Dobrynin, Pavel, Liu, Shiping, Tamazian, Gaik, Xiong, Zijun, Yurchenko, Andrey A., Krasheninnikova, Ksenia, Kliver, Sergey, Schmidt-Küntzel, Anne, Koepfli, Klaus-Peter, Johnson, Warren, Kuderna, Lukas F.K., García-Pérez, Raquel, Manuel, Marc de, Godinez, Ricardo, Komissarov, Aleksey, Makunin, Alexey, Brukhin, Vladimir, Qiu, Weilin, Zhou, Long, Li, Fang, Yi, Jian, Driscoll, Carlos, Antunes, Agostinho, Oleksyk, Taras K., Eizirik, Eduardo, Perelman, Polina, Roelke, Melody, Wildt, David, Diekhans, Mark, Marques-Bonet, Tomas, Marker, Laurie, Bhak, Jong, Wang, Jun, Zhang, Guojie, O’Brien, Stephen J.“…Cheetah genomes are on average 95 % homozygous compared to the genomes of the outbred domestic cat (24.08 % homozygous), Virunga Mountain Gorilla (78.12 %), inbred Abyssinian cat (62.63 %), Tasmanian devil, domestic dog and other mammalian species. …”
Publicado 2015
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450por Alvarez, Carolina, Aravena, Andrés, Tapia, Teresa, Rozenblum, Ester, Solís, Luisa, Corvalán, Alejandro, Camus, Mauricio, Alvarez, Manuel, Munroe, David, Maass, Alejandro, Carvallo, Pilar“…Gene lists obtained from aCGH analysis were analyzed for Gene Ontology enrichment using GOrilla and DAVID tools. RESULTS: Genomic profiling of the tumors showed specific alterations associated to BRCA1 or 2 mutation status, and BRCA1 expression in the tumors, affecting relevant cellular processes. …”
Publicado 2016
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451por Thybert, David, Roller, Maša, Navarro, Fábio C.P., Fiddes, Ian, Streeter, Ian, Feig, Christine, Martin-Galvez, David, Kolmogorov, Mikhail, Janoušek, Václav, Akanni, Wasiu, Aken, Bronwen, Aldridge, Sarah, Chakrapani, Varshith, Chow, William, Clarke, Laura, Cummins, Carla, Doran, Anthony, Dunn, Matthew, Goodstadt, Leo, Howe, Kerstin, Howell, Matthew, Josselin, Ambre-Aurore, Karn, Robert C., Laukaitis, Christina M., Jingtao, Lilue, Martin, Fergal, Muffato, Matthieu, Nachtweide, Stefanie, Quail, Michael A., Sisu, Cristina, Stanke, Mario, Stefflova, Klara, Van Oosterhout, Cock, Veyrunes, Frederic, Ward, Ben, Yang, Fengtang, Yazdanifar, Golbahar, Zadissa, Amonida, Adams, David J., Brazma, Alvis, Gerstein, Mark, Paten, Benedict, Pham, Son, Keane, Thomas M., Odom, Duncan T., Flicek, Paul“…Together with the Mus musculus and Rattus norvegicus genomes, this set of rodent genomes is similar in divergence times to the Hominidae (human-chimpanzee-gorilla-orangutan). By comparing the evolutionary dynamics between the Muridae and Hominidae, we identified punctate events of chromosome reshuffling that shaped the ancestral karyotype of Mus musculus and Mus caroli between 3 and 6 million yr ago, but that are absent in the Hominidae. …”
Publicado 2018
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452por Skelton, Jessica Katy, Ortega-Prieto, Ana Maria, Kaye, Steve, Jimenez-Guardeño, Jose Manuel, Turner, Jane, Malim, Michael H., Towers, Greg J., Dorner, Marcus“…IMPORTANCE Human immunodeficiency virus type 1 (HIV-1) infection is restricted to humans and some nonhuman primates (e.g., chimpanzee and gorilla). Alternative model systems based on simian immunodeficiency virus (SIV) infection of macaques are available but do not recapitulate all aspects of HIV-1 infection and disease. …”
Publicado 2019
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453“…The tool is open-source, implemented in JavaScript, and usable as a standalone library, or within Gorilla, jsPsych, and PsychoJS. In sum, MouseView.js is a freely available instrument for attention-tracking that is both reliable and valid, and that can replace eye tracking in certain web-based psychological experiments. …”
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454por Eschman, Bret, Todd, James Torrence, Sarafraz, Amin, Edgar, Elizabeth V., Petrulla, Victoria, McNew, Myriah, Gomez, William, Bahrick, Lorraine E.“…The MAAP is administered from a distance (remotely) by using Zoom, Gorilla Experiment Builder, an internet connection, and a home computer. …”
Publicado 2022
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455por Ferahtia, Seydali, Houari, Azeddine, Rezk, Hegazy, Djerioui, Ali, Machmoum, Mohamed, Motahhir, Saad, Ait-Ahmed, Mourad“…The considered algorithms are Farmland Fertility Optimizer (FO), African Vultures Optimization Algorithm (AVOA), Mountain Gazelle Optimizer (MGO), Gorilla Troops Optimizer (GTO), COOT algorithm, Hunger Games Search (HGS), Aquila Optimizer (AO), and Harris Hawks optimization (HHO). …”
Publicado 2023
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456“…Human amino acid sequences are conserved, with chimpanzee and gorilla showing more than 80% homology and bootstrap value based on 1000 replications. …”
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457por Tahir, Rana Adnan, Sehgal, Sheikh Arslan, Khattak, Naureen Aslam, Khan Khattak, Jabar Zaman, Mir, Asif“…Topology of tree presenting TNFRSF10A gene considered as outgroup. Human and gorilla shared more than 90% similarities with conserved amino acid sequence. …”
Publicado 2013
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458“…Analysis of HERV-W orthologous loci in non-human Catarrhini primates revealed species-specific insertions in the genomes of Chimpanzee (3), Gorilla (4), Orangutan (6), Gibbon (2) and especially Rhesus Macaque (66). …”
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459“…Recent study showed that gorillas possess yet another intermediate MHC organization compared to humans. …”
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460“…RESULTS: We used DNA methylation to predict the XCI status of X-linked genes with CpG islands across 12 different species: human, chimp, bonobo, gorilla, orangutan, mouse, cow, sheep, goat, pig, horse and dog. …”
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