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  1. 2681
    “…Only four environmental pandemic serovariants had previously been reported, and they were spread throughout Shanghai (O1:KUT, O3:K6), Jiangsu (O3:K6, O4:K48), Zhejiang (O3:K6), and Guangdong (O4:K9). Notably, 24 pandemic serovariants were detected within a short time frame (from 2006 to 2012). …”
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    Spreading of Pandemic Vibrio parahaemolyticus O3:K6 and Its Serovariants: A Re-analysis of Strains Isolated from Multiple Studies
  2. 2682
    “…METHODS: Complete clinicopathologic data and survival information of 1183 patients with GEP-NENs treated between 2005 and 2015 were collected from five medical centers in Guangdong Province, China. Patient survival was estimated using the Kaplan–Meier method and analyzed using the log-rank test; prognostic factors were analyzed using the Cox proportional hazards model. …”
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    Clinicopathologic characteristics and prognosis of gastroenteropancreatic neuroendocrine neoplasms: a multicenter study in South China
  3. 2683
    “…METHODS: We retrospectively analyzed the short- and long-term outcomes of proven pT4 colorectal cancer patients who underwent complete resection by laparoscopic or open surgery from 2006 to 2015 at Guangdong General Hospital. RESULTS: A total of 211 pT4 colorectal cancer patients were included in this analysis, including 101 cases in the laparoscopy (LAP) group and 110 cases in the open surgery (OPEN) group [including 15 (12.9%) cases of conversion to open surgery]. …”
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    Short- and long-term outcomes following laparoscopic vs open surgery for pathological T4 colorectal cancer: 10 years of experience in a single center
  4. 2684
    “…DESIGN: An observational study. SETTING: Guangdong General Hospital, China. PARTICIPANTS: 1639middle-aged and aged patients (mean age 57±6 years) diagnosed with rheumatic mitral disease, undergoing valve replacement surgery and receiving coronary angiography and transthoracic echocardiography before operation, were enrolled. …”
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    Value of pulmonary artery pressure in predicting in-hospital and one-year mortality after valve replacement surgery in middle-aged and aged patients with rheumatic mitral disease: an observational study
  5. 2685
    “…Three major genetic groups of cultivated Pyrus pyrifolia were revealed using nSSRs and a Bayesian statistical inference: (a) JPs; (b) cultivars from South-Central China northward to northeastern China, covering the main pear production area in China; (c) cultivars from southwestern China to southeastern China, including Yunnan, Guizhou, Guangdong, Guangxi, and Fujian Provinces. This reflected the synergistic effects of ecogeographical factors and human selection during cultivar spread and improvement. …”
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    Combined Analyses of Chloroplast DNA Haplotypes and Microsatellite Markers Reveal New Insights Into the Origin and Dissemination Route of Cultivated Pears Native to East Asia
  6. 2686
    “…We conducted a more comprehensive investigation of disability and associated factors among older adults receiving home-based care in rural Dongguan, a city in the central Guangdong Province of Southern China. METHODS: A total of 819 individuals aged ≥60 years were recruited from Dongguan home-based care system of via a two-stage selection process. …”
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    A more comprehensive investigation of disability and associated factors among older adults receiving home-based care in rural Dongguan, China
  7. 2687
    “…Here, we utilised the Guangdong Gut Microbiome Project (GGMP), the largest Eastern population-based gut microbiome dataset covering individuals with different economic statuses, to investigate the relationships between the gut microbiome and host physiology, diet, geography, physical activity and socioeconomic status. …”
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    Linking gut microbiota, metabolic syndrome and economic status based on a population-level analysis
  8. 2688
    “…OBJECTIVES: The aim of this study was, therefore, to investigate convergent validity of 3 Android Wear smartwatches—Polar M600 (Polar Electro Oy, Kempele, Finland), Huawei Watch (Huawei Technologies Co, Ltd, Shenzhen, Guangdong, China), Asus Zenwatch3 (AsusTek Computer Inc, Taipei, Taiwan)—and Fitbit Charge with an ActiGraph accelerometer for measuring steps and moderate to vigorous physical activity (MVPA) on both a day level and 15-min level. …”
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    The Accuracy of Smart Devices for Measuring Physical Activity in Daily Life: Validation Study
  9. 2689
    “…All animal procedures were approved by the Institutional Animal Care and Use Committee of Guangdong Medical University, China.…”
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    Effect of lentiviral vector-mediated overexpression of hypoxia-inducible factor 1 alpha delivered by pluronic F-127 hydrogel on brachial plexus avulsion in rats
  10. 2690
    “…FUND: National Natural Science Foundation of China [No. 81602646 & 81802339], Natural Science Foundation of Guangdong Province [No. 2016A030310254] and China Postdoctoral Science Foundation [No. 2016M600648].…”
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    Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma
  11. 2691
    “…Materials and methods: RNA levels of twelve m6A-related genes were detected in samples of 162 HCC patients who underwent curative resection (the Guangdong General Hospital dataset). We additionally analyzed the expression profiles of m6A-related genes in The Cancer Genome Atlas liver HCC dataset and two Gene Expression Omnibus datasets (GSE14520, GSE63898). …”
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    Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets
  12. 2692
    “…METHODS: Cases were recruited from neurology department in the First Affiliated Hospital of Guangdong Pharmaceutical University during September 2016–October 2017. …”
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    Effects of socioeconomic status on risk of ischemic stroke: a case-control study in the Guangzhou population
  13. 2693
    “…METHODS: The data for 59 children with severe PAH-CHD who underwent surgical correction, with or without postoperative medication, between May 2011 and June 2015 at the Guangdong Provincial People's Hospital were analyzed retrospectively. …”
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    Predictors of operability in children with severe pulmonary hypertension associated with congenital heart disease
  14. 2694
    “…Previous studies indicated that these highly pathogenic H7N9 viruses are virulent in chickens but have distinct pathotypes in mice. A/chicken/Guangdong/SD098/2017 (CK/SD098) is avirulent, with a 50% mouse lethal dose (MLD(50)) of >7.5 log(10) 50% egg infectious dose (EID(50)), whereas A/chicken/Hunan/S1220/2017 (CK/S1220) is virulent in mice, with an MLD(50) of 3.2 log(10) EID(50). …”
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    Amino Acid Mutations A286V and T437M in the Nucleoprotein Attenuate H7N9 Viruses in Mice
  15. 2695
    “…METHODS: 1854 students from 11 middle and high schools in Shenzhen, Guangdong Province, China, were sampled for this study. …”
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    Internet addiction mediates the association between cyber victimization and psychological and physical symptoms:moderation by physical exercise
  16. 2696
    “…Highly pathogenic avian influenza virus (HPAIV) subtype H5N1 was first detected in 1996 in Guangdong province, South China and started spreading throughout Asia in early 2004. …”
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    Risk-based surveillance for avian influenza control along poultry market chains in South China: The value of social network analysis
  17. 2697
    “…Moreover, ultraviolet-inactivated GM (chicken/Guangdong/GM/2014) NDV failed to induce the expression of IL-1β. …”
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    Newcastle disease virus RNA-induced IL-1β expression via the NLRP3/caspase-1 inflammasome
  18. 2698
    “…We evaluated the incidence data of COVID-19 in Guangdong to analyze the tendency of the pandemic and compared it with inpatient data. …”
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    Real-World Scenario of Patients With Lung Cancer Amid the Coronavirus Disease 2019 Pandemic in the People’s Republic of China
  19. 2699
    “…METHODS: Data from CTONG0901 clinical trial and medical records of Guangdong Lung Cancer Institute (GLCI) were retrospectively pooled. …”
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    Concomitant genetic alterations having greater impact on the clinical benefit of EGFR‐TKIs in EGFR‐mutant advanced NSCLC than BIM deletion polymorphism
  20. 2700
    “…METHODS: We analyzed 3450 consecutive patients undergoing CAG/PCI from a prospective cohort in Guangdong Provincial People’s Hospital. CI-AKI was defined as a serum creatinine elevation ≥50% or 0.3 mg/dL from baseline within the first 48 to 72 h after the procedure. …”
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    Population attributable risk estimates of risk factors for contrast-induced acute kidney injury following coronary angiography: a cohort study
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