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2701por Yan, Tingting, Mullany, Luke C, Subedi, Seema, Hazel, Elizabeth A, Khatry, Subarna K, Mohan, Diwakar, Zeger, Scott, Tielsch, James M, LeClerq, Steven C, Katz, Joanne“…Risk was lower with increasing maternal height from <145 cm to 145–150 cm (aHR: 0.78, 95% CI: (0.65 to 0.94)) to ≥150 cm (aHR: 0.57, 95% CI: (0.47 to 0.68)), four or more antenatal care (ANC) visits (aHR: 0.67, 95% CI: (0.53 to 0.86)) and education >5 years (aHR: 0.75, 95% CI: (0.62 to 0.92)). …”
Publicado 2023
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2702por Ilie, Silvia Mihaela, Briot, Nathalie, Constantin, Guillaume, Roussot, Nicolas, Ilie, Alis, Bergeron, Anthony, Arnould, Laurent, Beltjens, Françoise, Desmoulin, Isabelle, Mayeur, Didier, Kaderbhai, Courèche, Hennequin, Audrey, Jankowski, Clémentine, Padeano, Marie Martine, Costaz, Helène, Amet, Alix, Coutant, Charles, Coudert, Bruno, Bertaut, Aurélie, Ladoire, Sylvain“…Factors associated with the achievement of pathologic complete response (pCR) and survival were studied among hormone receptor positive (HR+) and negative (HR–) eBC. RESULTS: A total of 280 HR+ (61% HER2-low), and 231 HR– (28% HER2-low) eBC were included. …”
Publicado 2023
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2703por Strobach, Dorothea, Haimerl, Lisa, Mannell, Hanna, Stief, Christian G., Karl, Alexander, Grimm, Tobias, Buchner, Alexander“…In univariate analysis (log-rank test (p)/Cox regression (HR, 95% CI, p)), polypharmacy (p = 0.036/HR = 2.83, 95% CI = 1.02–7.90, p = 0.047), calcium channel blockers (p = 0.046/HR = 2.47, 95% CI = 0.97–6.27, p = 0.057) and proton pump inhibitors (p = 0.015/HR = 3.16, 95% CI = 1.18–8.41, p = 0.022) had a significant negative impact on RFS in RC patients, statins (p = 0.025/HR = 0.14, 95% CI = 0.02–1.06, p = 0.057) a positive effect on RFS in FD patients, angiotensin-converting enzyme inhibitors (p = 0.008/HR = 10.74, 95% CI = 1.20–96.17, p = 0.034) and magnesium (p = 0.042/HR = 5.28, 95% CI = 0.88–31.59, p = 0.067) a negative impact on CSS in FD patients. …”
Publicado 2023
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2704por Strasser-Weippl, Kathrin, Horick, Nora, Smith, Ian E, O’Shaughnessy, Joyce, Ejlertsen, Bent, Boyle, Frances, Buzdar, Aman U, Fumoleau, Pierre, Gradishar, William, Martin, Miguel, Moy, Beverly, Piccart-Gebhart, Martine, Pritchard, Kathleen I, Lindquist, Deborah, Rappold, Erica, Finkelstein, Dianne M, Goss, Paul E“…This difference was explainable by a significantly higher hazard of recurrence in years 1 to 5 in HER2+ HR- compared to HER2+ HR+ patients, with a mean risk of recurrence of 9%/year for HR- versus 5%/year in HR+ patients (hazard ratio 0.59, P = 0.002 for years 1 to 5). …”
Publicado 2015
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2705por Carstensen, Bendix, Read, Stephanie H, Friis, Søren, Sund, Reijo, Keskimäki, Ilmo, Svensson, Ann-Marie, Ljung, Rickard, Wild, Sarah H, Kerssens, Joannes J, Harding, Jessica L, Magliano, Dianna J, Gudbjörnsdottir, Soffia“…HRs were increased for cancer of the stomach (men, HR 1.23 [1.04, 1.46]; women, HR 1.78 [1.49, 2.13]), liver (men, HR 2.00 [1.67, 2.40]; women, HR 1.55 [1.14, 2.10]), pancreas (men, HR 1.53 [1.30, 1.79]; women, HR 1.25 [1.02,1.53]), endometrium (HR 1.42 [1.27, 1.58]) and kidney (men, HR 1.30 [1.12, 1.49]; women, HR 1.47 [1.23, 1.77]). …”
Publicado 2016
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2706por Gu, Fangyi, Xiao, Qian, Chu, Lisa W., Yu, Kai, Matthews, Charles E., Hsing, Ann W., Caporaso, Neil E.“…We also observed suggestive associations in either short or long sleepers, which did not reach overall significance (P(trend) >0.05), including increased risks in male short sleepers for cancers of head and neck (HR(<5vs.7-8 hours) = 1.39; 95%CI:1.00–1.95), bladder (HR(5-6vs.7-8 hours) = 1.10; 95%CI:1.00–1.20), thyroid (HR(<5 vs. 7–8 hours) = 2.30; 95%CI:1.06, 5.02), Non-Hodgkin Lymphoma (NHL) (HR(5-6vs.7-8 hours) = 1.17; 95%CI:1.02–1.33), and myeloma (HR(<5vs.7-8 hours) = 2.06; 95%CI:1.20–3.51). …”
Publicado 2016
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2707por Lund, C M, Nielsen, D, Dehlendorff, C, Christiansen, A B, Rønholt, F, Johansen, J S, Vistisen, K K“…Poor PS in younger and elderly patients was related to shorter DFS (HR=1.95, p=0.002; HR=1.6, p=0.035, respectively) and overall survival (OS; HR=2.28, p<0.001; HR=2.03, p=0.002). …”
Publicado 2016
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2708por Halland, Frode, Morken, Nils-Halvdan, DeRoo, Lisa A, Klungsøyr, Kari, Wilcox, Allen J, Skjærven, Rolv“…RESULTS: Mothers with perinatal losses had increased crude mortality compared with mothers without; total: HR 1.3 (95% CI 1.3 to 1.4), cardiovascular: HR 1.8 (1.5 to 2.1), non-cardiovascular: HR 1.3 (1.2 to 1.4). …”
Publicado 2016
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2709“…Additionally, the reduced 8-gene signature was sufficient and effective in predicting survival in liver and five other cancers: liver (HR = 2.36, P = 0.0003; HR = 2.43, P = 0.0002 and HR = 3.45, P = 0.0007), head and neck (HR = 1.64, P = 0.004), renal papillary cell (HR = 2.31, P = 0.04), lung (HR = 1.45, P = 0.03), pancreas (HR = 1.96, P = 0.006) and endometrial (HR = 2.33, P = 0.003). …”
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2710por Kasamatsu, Elena, Rodríguez Riveros, María Isabel, Soilan, Ana María, Ortega, Marina, Mongelós, Pamela, Páez, Malvina, Castro, Amalia, Cristaldo, Carmen, Báez, Fátima Romina, Centurión, Claudia Carolina, Vester, Jaime, Barrios, Hernán, Villalba, Griselda, Amarilla, María Luisa, Giménez, Graciela, Caubere, Elodie, Hernández, María de la Luz, Baena, Armando, Almonte, Maribel, Herrero, Rolando, Mendoza, Laura Patricia“…This study aimed to explore factors associated with hrHPV infection and high-grade cervical neoplasia in hrHPV-positive (hrHPV+) women from Paraguay. …”
Publicado 2019
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2711por Ren, Chunguang, Xu, Huiying, Xu, Guangjun, Liu, Lei, Liu, Guoying, Zhang, Zongwang, Cao, Jun-Li“…METHODS: Eighty‐six patients undergoing EITs were divided into three groups: RD1 (dexmedetomidine at an initial dose of 0.5 μg/kg for 10 min adjusted to 0.2 μg kg(−1) hr(−1) throughout EIT), RD2 (dexmedetomidine at an initial dose of 0.5 μg/kg for 10 min adjusted to 0.4 μg kg(−1) hr(−1) throughout EIT), and RD3 (dexmedetomidine at an initial dose of 0.5 μg/kg for 10 min adjusted to 0.6 μg kg(−1) hr(−1) throughout EIT). …”
Publicado 2019
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2712“…After adjustment for confounders, rates of VLOSLP were higher among migrants from Africa (hazard ratio [HR] = 2.0, 95% CI = 1.4–2.7), North America (HR = 1.4, 95% CI = 1.0–1.9, P = .04), Europe (HR = 1.3, 95% CI = 1.2–1.4), Russian-Baltic regions (HR = 1.6, 95% CI = 1.4–1.9), and Finland (HR = 1.6, 95% CI = 1.5–1.7). …”
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2713por Deitelzweig, Steven, Keshishian, Allison, Li, Xiaoyan, Kang, Amiee, Dhamane, Amol D., Luo, Xuemei, Balachander, Neeraja, Rosenblatt, Lisa, Mardekian, Jack, Pan, Xianying, Nadkarni, Anagha, Di Fusco, Manuela, Garcia Reeves, Alessandra B., Yuce, Huseyin, Lip, Gregory Y. H.“…Apixaban was associated with a lower risk of stroke/SE and MB compared with dabigatran (stroke/SE: HR = .65; 95% CI = .47‐.89; MB: HR = .60; 95% CI = .49‐.73) and rivaroxaban (stroke/SE: HR = .72; 95% CI = .59‐.86; MB: HR = .50; 95% CI = .45‐.55). …”
Publicado 2019
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2714“…The meta-analysis indicated that positive surgical margin (pooled HR = 1.47; 95% CI:1.24–1.73; P < 0.001), higher Fuhrman grade (pooled HR = 1.58; 95% CI:1.10–2.28; P = 0.013), higher pathological stage (pooled HR = 1.72; 95% CI:1.40–2.12; P < 0.001) and large tumor size (pooled HR = 1.09; 95% CI:1.03–1.16; P = 0.003) were significantly associated with recurrence risk. …”
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2715por Liu, Shuwen, Xiao, Gengfu, Chen, Yibang, He, Yuxian, Niu, Jinkui, Escalante, Carlos R, Xiong, Huabao, Farmar, James, Debnath, Asim K, Tien, Po, Jiang, Shibo“…BACKGROUND: Studies on the fusion-inhibitory peptides derived from the heptad repeat 1 and 2 (HR1 and HR2) regions of the HIV-1 envelope glycoprotein gp41 provided crucial information on the viral fusogenic mechanism. …”
Publicado 2004
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2716por Zhang, Lianghao, Li, Longqing, Liu, Junxiao, Wang, Jiange, Fan, Yafeng, Dong, Biao, Zhu, Zhaowei, Zhang, Xuepei“…Additionally, the elevated platelet-to-lymphocyte ratio was related to a poor OS (HR = 1.29, 95% CI: 1.07–1.54, P = .007), CSS (HR = 1.14, 95%CI = 0.98–1.34, P = .02) and PFS (HR = 1.2, 95%CI: 1.08–1.34, P = .0008). …”
Publicado 2020
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2717“…However, innovative HR interventions and messaging may also develop in response to such a crisis. …”
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2718por Song, Li, Lyu, Yuanjing, Ding, Ling, Li, Xiaoxue, Gao, Wen, Wang, Ming, Hao, Min, Wang, Zhilian, Wang, Jintao“…PURPOSE: High-risk human papillomavirus (HR-HPV) infection is widely known as the major cause of cervical cancer and there are notable differences in HR-HPV prevalence and genotype distribution in different populations. …”
Publicado 2020
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2719“…There were no significant differences between under-dosing and on-label dosing with respect to stroke/systematic embolism (HR: 1.01, 95% CI: 0.93–1.09), major bleeding (HR: 0.98, 95% CI: 0.77–1.19), intracranial haemorrhage (HR: 1.07, 95% CI: 0.74–1.40), gastrointestinal bleeding (HR: 1.10, 95% CI: 0.82–1.39), and myocardial infarction (HR: 1.07, 95% CI: 0.89–1.25), except for an increased risk of death (HR: 1.37, 95% CI: 1.01–1.73). …”
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2720“…It is demonstrated that UACR predicted an increased risk of stroke using cutoff value of either 0.43 (HR, 2.39; 95% CI: 1.24 - 4.61; P <0.01), 10 mg/g (HR, 1.60; 95% CI: 1.30 - 1.97; P < 0.01) or 30 mg/g (HR, 1.84; 95% CI: 1.49 - 2.28; P < 0.01). …”
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