“…CONCLUSION: Although collectively viewed as HR-positive breast cancers, certain distinctions exist between bone metastatic breast cancers with different HR statuses in survival outcome. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The time to LMC from diagnosis of LC was significantly shorter in EGFRm than ALK (H.R.:4.89, P=0.027), w/oDM (H.R.:2.96, P<0.0001), and SCLC (H.R.:7.23, P<0.0001). …”
Enlace del recurso
Enlace del recurso

“…Baseline factors, including vertical CDR ≥ 0.7 (hazard ratio [HR] = 2.12), vertical cupping (HR = 1.93), ISNT rule violation (HR = 2.84), disc ovality ≥ 1.2 (HR = 1.61), PPA-to-DA ratio ≥ 0.4 (HR = 1.77), CRVT nasalization ≥ 60% (HR = 1.77), vessel narrowing/sclerotic change (HR = 2.13), DH history (HR = 5.60), and baseline intraocular pressure ≥ 14 mmHg (HR = 1.70) were significantly associated with glaucoma conversion (all Ps < 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Despite similar stroke/SE risks, dabigatran and apixaban were associated with significantly lower MB/CRNMB risks compared to rivaroxaban (HR 0.86, 95%CI (0.83–0.90); HR 0.86, 95%CI (0.83–0.89), respectively) and edoxaban (HR 0.91, 95%CI (0.83–0.99); HR 0.86, 95%CI (0.81–0.91), respectively), and apixaban with significantly lower major bleeding risks compared to dabigatran (HR 0.86, 95%CI (0.80–0.92)) and edoxaban (HR 0.79, 95%CI (0.72–0.86)). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PURPOSE: We assessed the systemic treatment choices and outcomes in patients diagnosed with human epidermal growth factor receptor-2-positive (HER2 +) advanced breast cancer (ABC), for the first four lines of systemic therapy and by hormone receptor (HR) status. METHODS: We identified 330 patients diagnosed with HER2 + ABC in 2013–2018 in the Southeast of The Netherlands, of whom 64% with HR + /HER2 + and 36% with HR-/HER2 + disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Respiratory distress was the highest risk with HR 9,46, followed by asphyxia with HR 5,08, mother’s death with HR 227, extra-health facility with HR 1,97, symmetrical SGA with HR 1,97, preterm-AGA with HR 1,75, low birth weight (LBW) with HR 1,64, primary health facility with HR 1,33, and boys with HR 1,16 consecutively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…TMB‐High (TMB‐H): OS (HR = 0.86, 95% CI [0.74, 1.00], p = 0.05); PFS (HR = 0.71, 95% CI [0.6, 0.85], p < 0.001). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…FED use was associated with chemotherapy one-year pre-admission (adjusted hazard ratio (aHR) 2.60, 95% CI: 1.80–3.70), ≥1 ED visit in the previous year (aHR: 1.80, 95% CI 1.20–2.80), ≥15 pre-admission ambulatory visits (aHR 1.54, 95% CI 1.06–2.34), previous opioid and benzodiazepine use (aHR: 1.40, 95% CI: 1.10–1.90 and aHR: 1.70, 95% CI: 1.10–2.40), Charlson Comorbidity Index ≥ 3 (aHR: 2.0, 95% CI: 1.2–3.4), diabetes (aHR: 1.60, 95% CI: 1.10–2.20), heart disease (aHR: 1.50, 95% CI: 1.10–2.20) and lung cancer (aHR: 1.70, 95% CI: 1.10–2.40). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mortality excesses for heart diseases for both sexes [men-class 3: HR = 1.32 (0.93–1.87); men-class 4: HR = 1.95 (0.99–3.85); women-class 3: HR = 1.49 (1.10–2.04)] and for acute respiratory diseases among women [HR = 2.31 (0.67-8.00)] were observed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We evaluated the performance of high-risk HPV (hrHPV) testing in routine screening. METHODS: In all, 25 871 women (29–61) enrolled in our population-based cohort study were offered both cytology and hrHPV testing. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Associations in those aged 15 to 24 y were also found for violent crime arrests with preliminary investigations (HR = 1.28, 95% CI 1.16–1.41, p < 0.001), non-violent crime convictions (HR = 1.22, 95% CI 1.10–1.34, p < 0.001), non-violent crime arrests (HR = 1.13, 95% CI 1.07–1.20, p < 0.001), non-fatal injuries from accidents (HR = 1.29, 95% CI 1.22–1.36, p < 0.001), and emergency inpatient or outpatient treatment for alcohol intoxication or misuse (HR = 1.98, 95% CI 1.76–2.21, p < 0.001). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The excretion of CM in FDB-HR was significantly higher than in PR or H-HR parrots. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In men, short sleep duration (< 6 h) was associated with incident diabetes (HR 1.35, 95% CI 1.01, 1.80), CHD (HR 1.41, 95% CI 1.06, 1.89) and diabetes-CHD (HR 2.34, 95% CI 1.20, 4.55). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compared with sulfonylureas, hazard ratios (HRs) for cardiovascular events were lower with GLP‐1RA (adjusted HR‐women: 0.57, 95% CI: 0.48–0.68; aHR‐men: 0.82, 0.71–0.95), dipeptidyl peptidase‐4 inhibitors (aHR‐women: 0.83, 0.77–0.89; aHR‐men: 0.85, 0.79–0.91) and SGLT‐2i (aHR‐women: 0.58, 0.46–0.74; aHR‐men: 0.69, 0.57–0.83). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Elevated resting heart rate (HR) is associated with worse outcomes in chronic HF, but little is known about the prognostic impact of serial HR measurement during hospital stay after acute HF. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Out of the 63 clinical and laboratory parameters, Age [adjusted hazard ratio (HR) 2.31; 95% CI 1.52–3.53], Male Gender (HR 1.72, 95% CI 1.06–2.85), Respiratory Distress (HR 1.79, 95% CI 1.32–2.53), Diabetes Mellitus (HR 1.21, 95% CI 0.83–1.77), Chronic Kidney Disease (HR 3.04, 95% CI 1.72–5.38), Coronary Artery Disease (HR 1.56, 95% CI − 0.91 to 2.69), respiratory rate > 24/min (HR 1.54, 95% CI 1.03–2.3), oxygen saturation below 90% (HR 2.84, 95% CI 1.87–4.3), Lymphocyte% in DLC (HR 1.99, 95% CI 1.23–2.32), INR (HR 1.71, 95% CI 1.31–2.13), LDH (HR 4.02, 95% CI 2.66–6.07) and Ferritin (HR 2.48, 95% CI 1.32–4.74) were found to be significant. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…ICI-based therapy significantly improved OS compared with non-ICI therapy in patients aged <65 years (HR, 0.74; P<0.00001), 65-74 years (HR, 0.73; P<0.00001), receiving first-line (HR, 0.75; P<0.00001) or second-line (HR, 0.72; P<0.00001) treatment, current or previous smokers (HR, 0.76; P<0.00001), and EGFR wild-type patients (HR, 0.76; P<0.00001), but not in patients aged ≥75 years (HR, 0.91; P=0.50), receiving third-line treatment (HR, 0.93; P=0.55), never smokers (HR, 0.84; P=0.10), or EGFR mutant patients (HR, 0.99; P=0.92). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, there was a significant negative association between YAP expression and an unsatisfactory survival of patients with lung cancer (P(h) = 0.327, crude HR = 1.652, 95% CI = 1.211–2.253 for YAP expression) and patients with NSCLC [disease-free survival (DFS): Ph = 0.693, crude HR = 2.562, 95% CI = 1.876–3.499 for YAP expression; Ph = 0.920, crude HR = 2.617, 95% CI = 1.690–4.052 for YAP-mRNA; OS: Ph = 0.878, crude HR = 1.777, 95% CI = 1.233–2.562 for YAP expression], especially in the Asian population (DFS: P(h) = 0.414, crude HR = 2.515, 95% CI = 1.755–3.063; OS: P(h) = 0.712, crude HR = 1.772, 95% CI = 1.214–2.587). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Factors associated with a significantly increased risk of GIB were baseline age [per 10-year increase; hazard ratio (HR) 1.62, 95% confidence interval (CI): 1.42-1.86], unemployment (HR: 1.70, 95%CI: 1.11-2.59), body mass index (BMI) (HR: 1.15, 95%CI: 1.01-1.32), gamma-glutamyl transferase (GGT) (HR: 1.05, 95%CI: 1.02-1.09), precursors of GIB (HR: 1.90, 95%CI: 1.37-2.63), cancer (HR: 1.47, 95%CI: 1.10-1.97), psychiatric disorders (HR: 1.32, 95%CI: 1.01-1.71), heart failure (HR: 1.46, 95%CI: 1.04-2.05), and liver disorders (HR: 3.20, 95%CI: 2.06-4.97). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CCRT was associated with a better OS (HR = 0.61, 95% CI 0.44–0.82), LRFS (HR = 0.62, 95% CI 0.50–0.78), and PFS (HR = 0.65, 95% CI 0.54–0.79), but with similar DMFS (HR = 0.81, 95% CI = 0.46–1.45) compared with two-dimensional RT (2DRT) alone. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso