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3341por Balsara, Rashna, Dang, Alexander, Donahue, Deborah L., Snow, Tiffany, Castellino, Francis J.“…Intrathecal injection of con-G, post-middle carotid artery occlusion (MCAO), caused a dramatic decrease in brain infarct size and swelling at 4 hr, compared to 26 hr, and significant recovery of neurological deficits was observed at 26 hr. …”
Publicado 2015
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3342por Cordel, Nadège, Ragin, Camille, Trival, Monique, Tressières, Benoît, Janky, Eustase“…OBJECTIVE: To assess high-risk human papillomavirus (HR HPV) cervical infections and their type distribution among healthy women in Guadeloupe, French West Indies. …”
Publicado 2015
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3343“…In parallel, mean blood vessel counts were 36.9% lower in hrRNASET2-vs. Avastin-treated mice and survival rates of hrRNASET2-treated mice were 50% at 73 days post-treatment, while the median survival time for untreated animals was 22 days. …”
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3344por Wurster, Stephanie, Hennes, Fabian, Parplys, Ann C., Seelbach, Jasna I., Mansour, Wael Y., Zielinski, Alexandra, Petersen, Cordula, Clauditz, Till S., Münscher, Adrian, Friedl, Anna A., Borgmann, Kerstin“…Effectiveness of combined irradiation and PARPi olaparib was evaluated in ten HNSCC cell lines, subdivided into HR-proficient and HR-deficient cell lines using a GFP-based reporter assay. …”
Publicado 2016
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3345por Keskin, Havva, Shen, Ying, Huang, Fei, Patel, Mikir, Yang, Taehwan, Ashley, Katie, Mazin, Alexander V., Storici, Francesca“…Generally, HR involves exchange of genetic information between two identical or nearly identical DNA molecules(1); however, HR can also occur between RNA molecules, as shown for RNA viruses(2). …”
Publicado 2014
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3346por Hong, Han-han, Hou, Li-kun, Pan, Xin, Wu, Chun-yan, Huang, Hai, Li, Bing, Nie, Wei“…Overall, a significant negative association was found between UCA1 levels and OS time (HR1.81, 95% CI1.52−2.17), including the following cancers analyzed independently: colorectal (HR2.61, 95% CI1.56−4.37), non-small cell lung (HR1.49, 95% CI1.16−1.90), gastric (HR2.19, 95% CI1.36−3.51), and ovarian (HR1.89, 95% CI1.14−3.12). …”
Publicado 2016
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3347por Zhao, Bailin, Zhang, Dapeng, Li, Chengmin, Yuan, Zheng, Yu, Fangzhi, Zhong, Shangwei, Jiang, Guibin, Yang, Yun-Gui, Le, X Chris, Weinfeld, Michael, Zhu, Ping, Wang, Hailin“…Homologous recombination (HR), catalyzed in an evolutionarily conserved manner by active RecA/Rad51 nucleofilaments, maintains genomic integrity and promotes biological evolution and diversity. …”
Publicado 2017
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3348por Shen, Junyi, He, Linye, Li, Chuan, Wen, Tianfu, Chen, Weixia, Lu, Changli, Yan, Lvnan, Li, Bo, Yang, Jiayin“…RESULTS: Independent factors for overall survival including alpha-fetoprotein level (hazard ratio (HR):1.292), tumor size (HR:1.092), tumor number (HR:1.472), microvascular invasion (HR:1.660), neutrophil to lymphocyte count ratio (NLR) (HR:1.428), major vascular invasion (HR:2.485) and satellite lesions(HR:1.392) were selected into the nomogram for survival. …”
Publicado 2016
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3349“…It was proven that only bone metastasis was not a prognostic factor in the HR+/HER2-, HR+/HER2+ and HR-/HER2+ subgroup (all, P > 0.05), and patients with brain metastasis had the worst cancer specific survival (CSS) in all the subgroups of BCS (all, P<0.01). …”
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3350por Hoshino, Yoshikazu, Mizuno, Seiya, Kato, Kanako, Mizuno-Iijima, Saori, Tanimoto, Yoko, Ishida, Miyuki, Kajiwara, Noriko, Sakasai, Tomoki, Miwa, Yoshihiro, Takahashi, Satoru, Yagami, Ken-ichi, Sugiyama, Fumihiro“…As the removal of hair improves the accuracy of in vivo imaging, gene-modified mice with a reporter gene are often crossed with Hos:HR-1 mutant mice homozygous for the spontaneous Hr(hr) mutation that exhibit a hair loss phenotype. …”
Publicado 2017
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3351por Mueck, Katharina, Rebholz, Simone, Harati, Mozhgan Dehghan, Rodemann, H. Peter, Toulany, Mahmoud“…Moreover, Akt1-KD decreased clonogenicity after treatment with Mitomycin C and HR repair, as tested by an HR-reporter assay. Double knockdown of Akt1 and Rad51 did not lead to a further decrease in HR compared to the single knockdown of Rad51. …”
Publicado 2017
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3352por Carrillo, Diego, Muñoz, Juan P., Huerta, Hernán, Leal, Gabriel, Corvalán, Alejandro, León, Oscar, Calaf, Gloria M., Urzúa, Ulises, Boccardo, Enrique, Tapia, Julio C., Aguayo, Francisco“…The hallmark of high-risk human papillomavirus (HR-HPV)-related carcinogenesis is E6 and E7 oncogene overexpression. …”
Publicado 2017
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3353“…The fitness indexes included the sum of recovery HR, recovery HR index, age-adjusted recovery HR index, and immediate HR. …”
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3354por Ferencziová, Veronika, Harami, Gábor M., Németh, Julianna B., Vellai, Tibor, Kovács, Mihály“…However, imprecise HR can lead to genome instability, highlighting the importance of HR quality control. …”
Publicado 2018
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3355por McCloskey, Jenny C., Martin Kast, W., Flexman, James P., McCallum, Dugald, French, Martyn A., Phillips, Michael“…BACKGROUND: Anal intraepithelial neoplasia is associated with high-risk human papillomavirus (hrHPV) as a precursor to anal cancer. However, factors other than hrHPV are likely to be involved and further study of cofactors is required because of the possibility of syndemic interactions. …”
Publicado 2017
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3356por Emerenziani, Gian Pietro, Ferrari, Dafne, Vaccaro, Maria Grazia, Gallotta, Maria Chiara, Migliaccio, Silvia, Lenzi, Andrea, Baldari, Carlo, Guidetti, Laura“…This study aimed to establish a practical reference equation to estimate the heart rate (HR) at individual ventilatory threshold (IVT) (HR(IVT)). …”
Publicado 2018
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3357por Mourot, Laurent“…The prescription of exercise for patients largely rely on heart rate recordings (percentage of maximal heart rate (HR(max)) or heart rate reserve). It is known that HR(max) decreases with high altitude and the duration of the stay (acclimatization). …”
Publicado 2018
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3358“…Mechanisms regulating differences in cortisol responsiveness between low (LR) and high response (HR) individuals have been poorly studied. In this context, we aimed to study key regulatory processes in cortisol dynamics at the head kidneys of LR and HR European sea bass. …”
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3359Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection“…BACKGROUND: High-risk human papillomavirus (hr-HPV) infection is a necessary cause of cervical cancer. …”
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3360por Ruan, Baoyang, Liu, Qian, Chen, Yin, Niu, Xiaosai, Wang, Xuefeng, Zhang, Chengcheng, Guo, Mengjiao, Zhang, Xiaorong, Cao, Yongzhong, Wu, Yantao“…In this study, a thermostable, attenuated vaccine candidate strain NDV/rHR09 was generated using the genotype VIII heat-resistant virulent NDV strain HR09 by the reverse genetics system. …”
Publicado 2020
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