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3801“…Of an inhaled dose of benzene, on average 0.11% (range 0.05-0.26%) was excreted as S-PMA with an apparent elimination half-life of 9.1 (standard error [SE] 0.7) hr and 3.9% (range 1.9-7.3%) as tt-MA with a half-life of 5.0 (SE 0.5) hr. …”
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3802por Hibbitts, S, Jones, J, Powell, N, Dallimore, N, McRea, J, Beer, H, Tristram, A, Fielder, H, Fiander, A N“…Overall HPV prevalence was 13.5% (9.3% age standardised) and the most frequent HR types were HPV 16, 31, 18 and 58. In HR HPV-positive cases 42.4% had a single HR type and they were predominant in women with severe cytological abnormalities. …”
Publicado 2008
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3803“…BACKGROUND: Formation of site specific genomic double strand breaks (DSBs), induced by the expression of a pair of engineered zinc-finger nucleases (ZFNs), dramatically increases the rates of homologous recombination (HR) between a specific genomic target and a donor plasmid. …”
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3804“…The main predictors of all-cause mortality at age <60 years in the fully adjusted model were high sessional alcohol intake (hazard ratio (HR) 2.04, 95% CI 1.10-3.80), severe hypertension >160/95 mm Hg (HR 1.68, 95% CI 1.09-2.60), diabetes (HR 3.28, 95% CI 1.89-5.69), and BMI (HR 1.04, 95% CI 1.00-1.07). …”
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3805por Gerrits, Monique M., Chen, Min, Theeuwes, Myrte, van Dekken, Herman, Sikkema, Marjolein, Steyerberg, Ewout W., Lingsma, Hester F., Siersema, Peter D., Xia, Bing, Kusters, Johannes G., van der Woude, C. Janneke, Kuipers, Ernst J.“…RESULTS: Adjusting for age, we found statistically significant Hazard ratios (HR) between development of CRC, and low grade dysplasia (HR5.5; 95%CI 2.6-11.5), abnormal DNA ploidy (DNA index (DI) 1.06-1.34, HR4.7; 95%CI 2.9-7.8 and DI>1.34, HR6.6; 95%CI 3.7-11.7) and p53 immunopositivity (HR3.0; 95%CI 1.9-4.7) over time. …”
Publicado 2011
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3806por Shigematsu, Hideo, Kawaguchi, Hidetoshi, Nakamura, Yoshiaki, Tanaka, Kimihiro, Shiotani, Satoko, Koga, Chinami, Nishimura, Sumiko, Taguchi, Kenichi, Nishiyama, Kenichi, Ohno, Shinji“…When patients were categorized into 4 subgroups by the expression of hormone receptor (HR) and HER-2 status, the median OS times of the HR-positive/HER-2-negative, HR-positive/HER-2-positive, HR-negative/HER-2-positive, and HR-negative/HER-2-negative subtypes were 2.2, 2.4, 1.6, and 1.0 years in cohort A and 4.5, 5.1, 5.0, and 1.4 years in cohort B. …”
Publicado 2011
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3807por Moon, Joon Ho, Park, Eun-Ah, Lee, Whal, Yin, Yong Hu, Chung, Jin Wook, Park, Jae Hyung, Lee, Hae-Young, Kang, Hyun-Jae, Kim, Hyo-Soo“…These values were compared between the groups with differing heart rates (HR): mean HR < 65 or ≥ 65 and HR variability (HRV) < 15 or ≥ 15. …”
Publicado 2011
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3808por Jiang, Yiwei, Yin, Wenjin, Zhou, Liheng, Yan, Tingting, Zhou, Qiong, Du, Yueyao, Shen, Zhenzhou, Shao, Zhimin, Lu, Jinsong“…FINDINGS: We found significant improvement in the additional capecitabine arm versus control in disease-free survival (DFS) (HR = 0.83, 95% CI: 0.71–0.98, P = 0.027), overall survival (OS) (HR = 0.71, 95% CI: 0.57–0.88, P = 0.002), distant recurrence (HR = 0.79, 95% CI: 0.66–0.94, P = 0.008) and the death from breast cancer only (HR = 0.65, 95% CI: 0.51–0.83, P = 0.001). …”
Publicado 2012
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3809por Jacquemier, Jocelyne, Boher, Jean-Marie, Roche, Henri, Esterni, Benjamin, Serin, Daniel, Kerbrat, Pierre, Andre, Fabrice, Finetti, Pascal, Charafe-Jauffret, Emmanuelle, Martin, Anne-Laure, Campone, Mario, Viens, Patrice, Birnbaum, Daniel, Penault-Llorca, Frédérique, Bertucci, François“…The luminal A subtype did not benefit from docetaxel (HR = 1.16, 95% CI 0.73 to 1.84); the reduction in the relapse risk was 53% (HR = 0.47, 95% CI 0.22 to 1.01), 34% (HR = 0.66, 95% CI 0.37 to 1.19), and 12% (HR = 0.88, 95% CI 0.49 to 1.57) in the luminal B, HER2-overexpressing, and triple-negative subtypes, respectively. …”
Publicado 2011
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3810por Tarantino, I, Warschkow, R, Worni, M, Merati-Kashani, K, Köberle, D, Schmied, B M, Müller, S A, Steffen, T, Cerny, T, Güller, U“…RESULTS: In risk-adjusted Cox proportional hazard regression analyses, preoperative CEA level (hazard ratio (HR): 1.98, 95% confidence interval (CI): 1.36–2.90, P<0.001), distance from anal verge (<5 cm: HR: 1.93, 95% CI: 1.11–3.37; P=0.039), older age (HR: 1.07, 95% CI: 1.05–1.09; P<0.001), lower body mass index (HR: 0.94, 95% CI: 0.89–0.98; P=0.006), advanced tumour stage (stage II HR: 1.41, 95% CI: 0.85–2.32; stage III HR: 2.08, 95% CI: 1.31–3.31; P=0.004), R 1 resection (HR: 5.65, 95% CI: 1.59–20.1; P=0.005) and chronic kidney disease (HR: 2.28, 95% CI: 1.03–5.04; P=0.049) were all predictors for poor overall survival. …”
Publicado 2012
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3811“…After adjusted other risk factors, in patients without T2DM, comparing with HR <66 b.p.m., the increase of HR level was associated with worse prognosis (P < 0.05). …”
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3812“…T. violacea and muscarine produced dose-dependent decreases in HR, while the effect of atropine on HR varied. After atropine pre-treatment, dose-dependent increases in BP and HR were observed with T. violacea; while the BP and HR effects of muscarine were nullified. …”
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3813por Qiu, Zhihua, Chen, Xiao, Zhou, Yanzhao, Lin, Jibin, Ding, Dan, Yang, Shijun, Chen, Fen, Wang, Min, Zhu, Feng, Yu, Xian, Zhou, Zihua, Liao, Yuhua“…In this study, we selected six peptides (rR32, rR72, rR215, hR32, hR72, and hR215) belonging to potential epitopes of rat and human renin. …”
Publicado 2013
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3814por Puzone, Roberto, Savarino, Graziana, Salvi, Sandra, Dal Bello, Maria Giovanna, Barletta, Giulia, Genova, Carlo, Rijavec, Erika, Sini, Claudio, Esposito, Alessia Isabella, Ratto, Giovanni Battista, Truini, Mauro, Grossi, Francesco, Pfeffer, Ulrich“…RESULTS: In our study GAPDH gene over expression was found to be an adverse prognostic factor in early stages NSCLC (n = 82 HR = 1.30 p = 0.050). This result was confirmed in 5 of 6 public datasets analyzed: Shedden et al. 2008: n = 442 HR = 1.54 p < 0.0001; Lee et al. 2008: n = 138 HR = 1.31 p = 0.043; Tomida et al. 2009: n = 117 HR = 1.59 p = 0.004; Roepman et al. 2009: n = 172 (TPI1 gene) HR = 1.51 p = 0.009; Okayama et al. 2012: n = 226 HR = 3.19 p < 0.0001; Botling et al. 2013: n = 196 HR = 1.00 p = 0.97). …”
Publicado 2013
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3815“…Blacks had an increased risk of mortality in the intermediate (HR = 1.52; 1.20, 1.92) and highest (HR = 1.53; 1.22, 1.92) SES categories. …”
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3816por Wang, Yingqiang, Luo, Qianqian, Li, Youping, Deng, Shaolin, Wei, Shiyou, Li, Xianglian“…OBJECTIVES: To evaluate the efficacy and safety of radiofrequency ablation (RFA) versus hepatic resection (HR) for early hepatocellular carcinoma (HCC) meeting the Milan criteria. …”
Publicado 2014
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3817por Ezechi, Oliver Chukwujekwu, Ostergren, Per Olof, Nwaokorie, Francisca Obiageri, Ujah, Innocent Achaya Otobo, Odberg Pettersson, Karen“…In this study we investigated the effect of HIV infection and treatment on high-risk (hr) human papilloma virus (HPV) prevalence and distribution. …”
Publicado 2014
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3818por Geter, David R, Chang, Lina W, Hanley, Nancy M, Ross, Matthew K, Pegram, Rex A, DeAngelo, Anthony B“…PRH were exposed to individual THMs for 4 hr then assayed for DNA SB. F344/N rats were exposed to individual THMs for 4 hr, 2 weeks, and to BDCM for 5 wk then tested for DNA SB. …”
Publicado 2004
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3819por Johnson, Derek C., Bhatta, Madhav P., Smith, Jennifer S., Kempf, Mirjam-Colette, Broker, Thomas R., Vermund, Sten H., Chamot, Eric, Aryal, Shilu, Lhaki, Pema, Shrestha, Sadeep“…Data on high-risk HPV (HR-HPV) types are not currently available for rural populations in Nepal. …”
Publicado 2014
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3820por Intaraphet, Suthida, Kasatpibal, Nongyao, Søgaard, Mette, Khunamornpong, Surapan, Patumanond, Jayanton, Chandacham, Anchalee, Chitapanarux, Imjai, Siriaunkgul, Sumalee“…In patients with advanced SNEC, age >60 years had a strong prognostic impact (HR 2.6, 95% CI 1.0–6.5) while the International Federation of Gynecology and Obstetrics stages III and IV were prognostic factors for patients with advanced stage ADC (HR 2.9, 95% CI 2.0–4.4 and HR 4.5, 95% CI 2.6–7.9, respectively) and SCC (HR 1.7, 95% CI 1.4–2.0 and HR 3.7, 95% CI 2.8–4.9, respectively) compared with the International Federation of Gynecology and Obstetrics stage IIB. …”
Publicado 2014
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