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  1. 481
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    CanAssist Breast Impacting Clinical Treatment Decisions in Early-Stage HR+ Breast Cancer Patients: Indian Scenario
  2. 482
    “…METHODS: We collected urine samples over 7 consecutive days, including two 24-hr samples, from 25 children living in an agricultural community. …”
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    Organophosphate pesticide dose estimation from spot and 24-hr urine samples collected from children in an agricultural community
  3. 483
    “…BACKGROUND: National medical/surgical organizations have recommended the use of neoadjuvant endocrine therapy (NET) to bridge surgery delay of weeks to months for patients with hormone receptor positive (HR+) breast cancer during the ongoing coronavirus disease 2019 (COVID-19) pandemic. …”
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    Effectiveness of a Short Duration of Neoadjuvant Endocrine Therapy in Patients with HR+ Breast Cancer—An NCDB Analysis (2004–2016)
  4. 484
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    Online Artículo Texto
    HR Max Prediction Based on Age, Body Composition, Fitness Level, Testing Modality and Sex in Physically Active Population
  5. 485
    “…High-resolution peripheral computed tomography (HR-pQCT) was developed to image bone microarchitecture in vivo at peripheral skeletal sites. …”
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    Online Artículo Texto
    The clinical application of high-resolution peripheral computed tomography (HR-pQCT) in adults: state of the art and future directions
  6. 486
    “…Overall, our findings demonstrated that VPA influences HR repair and cell cycle through down-regulating MUS81-pRPA2 pathway in response to HU treatment.…”
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    Online Artículo Texto
    Valproic Acid Regulates HR and Cell Cycle Through MUS81-pRPA2 Pathway in Response to Hydroxyurea
  7. 487
    “…Palbociclib has shown satisfactory outcomes when combined with endocrine therapy (ET) in hormone receptor–positive and human epidermal growth factor receptor 2–negative (HR+/HER2–) metastatic breast cancer (MBC). However, data in Asia are currently scarce.This retrospective study aimed to evaluate the real-world effectiveness, sensitivity, and toxicity of palbociclib plus ET in HR+/HER2– MBC in North China. …”
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    Real-world effectiveness and sensitivity of palbociclib plus endocrine therapy in HR+/HER2– patients with metastatic breast cancer
  8. 488
    por Jacobson, Anne
    Publicado 2022
    “…In updated biomarker and clinical subgroup analyses from the phase III MONALEESA trials, ribociclib demonstrated consistent improvements in overall survival when added to endocrine therapy in patients with HR-positive/HER2-negative advanced breast cancer.…”
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    Ribociclib Improves Overall Survival in HR+/HER2– Metastatic Breast Cancer Across Common Genomic and Clinical Subtypes
  9. 489
    “…Experiment 3 yielded 5.24% PD(T/RT) for HR+. CONCLUSIONS: The PD results show that the variability of harmonized HRRT is less than the T/RT variability of the HR+. …”
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    Harmonization of [(11)C]raclopride brain PET images from the HR+ and HRRT: method development and validation in human subjects
  10. 490
    “…BRCA1 depletion effectively abolished TRIM44-modulated cisplatin resistance and regulation of homologous recombination (HR) repair. Interestingly, TRIM44 interacted with FLNA, an upstream regulator of BRCA1 as specified by STRING V 11.5, and facilitated its stability and deubiquitination. …”
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    TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA
  11. 491
    “…The relationship between the cervico-vaginal microbiome and high-risk human papillomavirus (HR-HPV) is well observed. However, there is a lack of adequate research regarding the cervical microbiota in HR-HPV infection. …”
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    Exploring the Association Between Cervical Microbiota and HR-HPV Infection Based on 16S rRNA Gene and Metagenomic Sequencing
  12. 492
    “…HR3C (25Cr-20Ni-Nb-N) is a key material used in heat exchangers in supercritical power plants. …”
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    Precipitation Evolution in the Austenitic Heat-Resistant Steel HR3C upon Creep at 700 °C and 750 °C
  13. 493
    “…PURPOSE: To report the treatment utilization patterns for hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2−) breast cancer in urban mainland China (CancerMPact®). …”
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    Treatment of HR+/HER2− breast cancer in urban mainland China: results from the CancerMPact Survey 2019
  14. 494
    “…These data support first-line palbociclib plus an AI treatment for HR+/HER2− MBC. (Trial number NCT05361655).…”
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    Real-world study of overall survival with palbociclib plus aromatase inhibitor in HR+/HER2− metastatic breast cancer
  15. 495
    “…Thus, businesses need to examine the expectations of Human Resource (HR) professionals to adapt to the unexpected changes aroused by the novel COVID-19 pandemic. …”
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    The changing face of HR professionals’ expectations amidst COVID-19: a comparison in between Sri Lanka and foreign context
  16. 496
    “…BACKGROUND: Adjuvant chemotherapy is a major adjuvant treatment modality for hormonal receptor (HR)-positive and HER2-negative early breast cancer, but only 2%-20% of patients derive practical benefits. …”
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    RecurIndex assay as an aid for adjuvant chemotherapy decisions in HR-positive HER2-negative breast cancer patients
  17. 497
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    LC-HR/MS Analysis of Lipophilic Extracts from Calendula arvensis (Vaill.) L. Organs: An Unexplored Source in Cosmeceuticals
  18. 498
    “…OBJECTIVE: Patient monitoring in general wards primarily involves intermittent observation of temperature, heart rate (HR), respiratory rate (RR) and blood pressure performed by the nursing staff. …”
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    Contactless monitoring of respiratory rate (RR) and heart rate (HR) in non-acuity settings: a clinical validity study
  19. 499
    “…In this study, we dedicated to characterize the extended N-terminal motif (residues 1161–1168) of the so-called spike (S) heptad repeat 2 (HR2) region. Alanine scanning analysis of this motif verified its critical roles in S protein-mediated cell-cell fusion. …”
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    Design and characterization of novel SARS-CoV-2 fusion inhibitors with N-terminally extended HR2 peptides
  20. 500
    “…Our work develops a high-resolution reduced-complexity model (EASIUR-HR) to evaluate the disproportionate impacts of ground-level primary PM(2.5) emissions. …”
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    EASIUR-HR: A Model To Evaluate Exposure Inequality Caused by Ground-Level Sources of Primary Fine Particulate Matter
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