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721por Jacobs, Flavia, Gaudio, Mariangela, Benvenuti, Chiara, De Sanctis, Rita, Santoro, Armando, Zambelli, Alberto“…ABSTRACT: Several multigene assays have been developed to help clinicians in defining adjuvant treatment for patients with hormone-receptor-positive (HR+), human epidermal growth factor receptor-2 (HER2)–negative early breast cancer. …”
Publicado 2022
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722por Ahmed, Sameen, Vajeeha, Ayesha, Idrees, Muhammad, Hussain, Abrar, Munir, Rakhtasha, Zaidi, Gulshan, Zahid, Khadija, Ahmed, Rizwan, Fatima, Zareen, Rafique, Shazia, Achakzai, Niaz M.“…High-risk-human papillomavirus (HR-HPV)-induced cervical cancer is the second most common cause of death among females worldwide. …”
Publicado 2023
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723“…For reliable analysis of elements Na, Mg and Ni in food samples is it worthwhile to perform an extensive method validation of high-resolution continuum source flame atomic absorption spectrometry (HR-CS FAAS) according to the principle of pooled calibrations (PoPC). …”
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728por Casanova Mohr, Raimon, Casse, Gianluigi, Grinstein, Sebastian, Vilella, Eva, Voosebeld, Joost“…This paper presents a HV/HR-MAPS detector developed in the framework of the HV-CMOS collaboration for the ATLAS Inner Tracker update of the HL-LHC era. …”
Publicado 2019
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729por Yang, Chen, Rybchyn, Mark Stephen, De Silva, Warusavithana Gunawardena Manori, Matthews, Jim, Dixon, Katie Marie, Holland, Andrew J. A., Conigrave, Arthur David, Mason, Rebecca Sara“…In this study, topical application of NPS-2143 (228 or 2280 pmol/cm(2)) to Skh:hr1 female mice reduced UV-induced cyclobutane pyrimidine dimers (CPD) (p < 0.05) and oxidative DNA damage (8-OHdG) (p < 0.05) to a similar extent as the known photoprotective agent 1,25(OH)(2) vitamin D3 (calcitriol, 1,25D). …”
Publicado 2023
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730por Zattarin, Emma, Presti, Daniele, Mariani, Luigi, Sposetti, Caterina, Leporati, Rita, Menichetti, Alice, Corti, Chiara, Benvenuti, Chiara, Fucà, Giovanni, Lobefaro, Riccardo, Ligorio, Francesca, Provenzano, Leonardo, Vingiani, Andrea, Del Vecchio, Marta, Griguolo, Gaia, Sirico, Marianna, Bernocchi, Ottavia, Marra, Antonio, Zagami, Paola, Agostinetto, Elisa, Jacobs, Flavia, Di Mauro, Pierluigi, Esposito, Andrea, Giorgi, Carlo Alberto, Lalli, Luca, Boldrini, Laura, Giacchetti, Pier Paolo Berton, Schianca, Ambra Carnevale, Guarneri, Valentina, Pedersini, Rebecca, Losurdo, Agnese, Zambelli, Alberto, Generali, Daniele, Criscitiello, Carmen, Curigliano, Giuseppe, Pruneri, Giancarlo, de Braud, Filippo, Dieci, Maria Vittoria, Vernieri, Claudio“…Whether Human Epidermal growth factor Receptor 2 (HER2)-low status has prognostic significance in HR + /HER2- advanced Breast Cancer (aBC) patients treated with first-line Endocrine Therapy plus CDK 4/6 inhibitors remains unclear. …”
Publicado 2023
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731“…In this podcast, we discuss how real-world data in heterogeneous patient populations can complement clinical trial data in informing treatment decision making for patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2−) metastatic breast cancer. Specifically, our focus is on P-REALITY X, an observational retrospective analysis that was recently published in npj Breast Cancer. …”
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732“…The present study aimed to retrospectively assess the effects of human epidermal growth factor receptor 2 (HER2) expression on the diagnosis of patients with hormone receptor (HR)(+)/HER2(−) late-stage breast cancer undergoing advanced first-line endocrine-based treatment. …”
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733por Teng, Xinzhi, Zhang, Jiang, Zhang, Xinyu, Fan, Xinyu, Zhou, Ta, Huang, Yu-hua, Wang, Lu, Lee, Elaine Yuen Phin, Yang, Ruijie, Cai, Jing“…BACKGROUND: The immunohistochemical test (IHC) of HER2 and HR can provide prognostic information and treatment guidance for invasive breast cancer patients. …”
Publicado 2023
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734“…DS reflex after co-testing was cost-effective with incremental cost-effectiveness ratios per quality-adjusted life-year gained of $15,231 [95% confidence interval (CI), $10,717–$25,400] compared with co-testing with hrHPV pooled primary and genotyped reflex testing, and $23,487 (95% CI, $15,745–$46,175) compared with co-testing with hrHPV genotyping with no reflex test. …”
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735por Chiu, Joanne, Su, Fei, Joshi, Mukta, Masuda, Norikazu, Ishikawa, Takashi, Aruga, Tomoyuki, Zarate, Juan Pablo, Babbar, Naveen, Balbin, O. Alejandro, Yap, Yoon-SimEnlace del recurso
Publicado 2023
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736por Dimitriou, Despoina, Lamprianidou, Eleftheria, Tasis, Athanasios, Spiropoulos, Theodoros, Kimparidou, Chrysa, Papadakis, Stavros, Liapis, Konstantinos, Papoutselis, Menelaos, Vrachiolias, George, Mitroulis, Ioannis, Kotsianidis, IoannisEnlace del recurso
Publicado 2023
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737“…For in vivo optogenetic manipulations, rats stereotaxically received AAV8-GFAP-eNpHR3.0-mCherry or AAV8-GFAP-mCherry at the trigeminal nucleus caudalis (TNC). …”
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738por Chang, Yu-Cheng, Song, Junmin, Chang, Yu, Huang, Chin-Hsuan, Sudan, Aarushi, Chen, Pei-Chin, Chi, Kuan-Yu“…Therefore, when HR+/HER2- advanced breast cancer patients require the use of PPIs, it may be reasonable to consider using Ribociclib.…”
Publicado 2023
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739por Mandura Jarić, Ana, Čikoš, Ana, Pocrnić, Marijana, Aladić, Krunoslav, Jokić, Stela, Šeremet, Danijela, Vojvodić Cebin, Aleksandra, Komes, Draženka“…The aim of this study is the valorization of the bioactive potential of T. montanum L., an understudied Mediterranean plant species, and the in-depth elucidation of a polyphenolic profile with a UHPLC-HR MS/MS and NMR analysis. The total phenolic content (TPC) and antioxidant capacity (AC) were determined on heat-assisted (HAE), microwave-assisted (MAE) and subcritical water (SWE) extracts. …”
Publicado 2023
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740por Bergqvist, Mattias, Nordmark, Adrian, Williams, Amy, Paoletti, Costanza, Barlow, William, Cobain, Erin F., Mehta, Rita S., Gralow, Julie R., Hortobagyi, Gabriel N., Albain, Kathy S., Pusztai, Lajos, Sharma, Priyanka, Godwin, Andrew K., Thompson, Alastair M., Hayes, Daniel F., Rae, James M.“…CONCLUSIONS: DiviTum(®)TKa provides clinically meaningful information for patients with HR+MBC. Low TKa levels provide such a high NPV for rapid progression that such patients might forego additional therapy added to single agent ET. …”
Publicado 2023
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