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  1. 80801
    “…METHODS: Nine thousand nine hundred sixty-two elderly individuals (age ≥ 60 years old) derived from the prospective Dongfeng-Tongji cohort were included. Hazard ratio (HR) and corresponding 95% confidence interval (CI) were evaluated by Cox proportional hazard model to examine the associations between traditional anthropometric indices (body mass index [BMI], waist circumference [WC], waist-to-height ratio [WHtR]), novel anthropometric indices (visceral adiposity index [VAI], a body shape index [ABSI], body roundness index [BRI]) and diabetes risk. …”
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    Using different anthropometric indices to assess prediction ability of type 2 diabetes in elderly population: a 5 year prospective study
  2. 80802
    “…Compared with monotherapy, combination associated with a lower risk of failure (adjusted HR 0.79, 95% CI 0.72 to 0.88). Among monotherapies, considering etanercept as reference, adalimumab (1.28, 95% CI 1.03 to 1.59) and infliximab (2.41, 95% CI 1.85 to 3.15) had higher risk of failure. …”
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    Comparative effectiveness of first-line biological monotherapy use in rheumatoid arthritis: a retrospective analysis of the RECord-linkage On Rheumatic Diseases study on health care administrative databases
  3. 80803
    “…Analysis from the Cox regression model demonstrated that preoperative α-fetoprotein (AFP; <400 ng/ml vs. ≥400 ng/ml; HR=0.548; P=0.036) was an independent predictor of the survival time of patients with SHCC. …”
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    Impact of local tumor lesion treatments and preoperative indicators on the survival of patients with small hepatocellular carcinomas
  4. 80804
    “…Adults living in areas with the highest fifth of NO(2) concentration (>41.5 µg/m(3)) versus the lowest fifth (<31.9 µg/m(3)) were at a higher risk of dementia (HR=1.40, 95% CI 1.12 to 1.74). Increases in dementia risk were also observed with PM(2.5), PM(2.5) specifically from primary traffic sources only and L(night), but only NO(2) and PM(2.5) remained statistically significant in multipollutant models. …”
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    Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
  5. 80805
    “…The age- and sex-adjusted HR of re-infection for two-stage revision was 1.70 (0.58–5.00) when compared with one-stage revision. …”
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    One- and two-stage surgical revision of peri-prosthetic joint infection of the hip: a pooled individual participant data analysis of 44 cohort studies
  6. 80806
    “…Reduced CDX2 was associated with lymph node metastasis (p = 0.0167), distant metastasis (p = 0.0123), and unfavorable survival (multivariate analysis: p = 0.0008; HR (95%CI) 0.922 (0.988–0.997)) as well as BRAF(V600E), mismatch repair deficiency, and CpG island methylator phenotype. …”
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    CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway
  7. 80807
    “…The AAPR was identified as an independent prognostic factor after univariate and multivariate analyses (HR = 0.636, P = 0.003). The independent prognostic value of the AAPR was also confirmed in validation cohorts I and II. …”
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    The Predictive Value of Albumin-to-Alkaline Phosphatase Ratio for Overall Survival of Hepatocellular Carcinoma Patients Treated with Trans-Catheter Arterial Chemoembolization Therapy
  8. 80808
    “…Cox regression analysis demonstrated an independent predictor of CDH11 expression in GC prognosis (HR=1.482, 95% CI: 1.015–2.164). Furthermore, gene set enrichment analysis (GSEA) demonstrated that multiple tumor-related pathways, especially focal adhesion, were enriched in CDH11 highly expressed samples. …”
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    Co-expression network analysis identified CDH11 in association with progression and prognosis in gastric cancer
  9. 80809
    “…High baseline ALC was significantly associated with improved PFS (≥1500/μL; hazard ratio [HR]: 0.3715; 95% confidence interval [CI]: 0.1735–0.7955; P = 0.0108). …”
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    Predictive impact of absolute lymphocyte counts for progression-free survival in human epidermal growth factor receptor 2-positive advanced breast cancer treated with pertuzumab and trastuzumab plus eribulin or nab-paclitaxel
  10. 80810
    “…Spirometry tests and blood samples were consistently performed 2.5–4.5 hr before the interruption of the fasting. Assessment sessions comprised: spirometry, inflammatory [erythrocyte sedimentation rate (ESR); C-reactive protein (CRP)] and hematological [red and white blood cells (RBC, WBC); hemoglobin; hematocrit; mean corpuscular volume; mean corpuscular hemoglobin; platelets] indices. …”
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    The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study
  11. 80811
    “…Multiple (≥2) tumours had a lower recurrence free survival (HR of 4.60, CI 1.67-12.63, p = 0.003). CONCLUSIONS: Of the patients with pTa high-grade tumours who had a second TURBT after a complete first TURBT, 19.4% had a positive finding. …”
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    Is there a role for second transurethral resection in pTa high-grade urothelial bladder cancer?
  12. 80812
    “…Higher levels of NI were associated with higher mortality risk after adjusting for frailty and other covariates (HR per 0.1: 1.19 [95%CI 1.133–1.257]). CONCLUSIONS: Most nutrition-related parameters were correlated to frailty, but only low vitamin D was associated with higher risk for mortality across levels of frailty. …”
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    Frailty, nutrition-related parameters, and mortality across the adult age spectrum
  13. 80813
    “…Considering the survival time after sepsis, the mortality risk was lower for patients in the older group than for patients in the younger group (hazard ratio (HR) = 0.254, 95% confidence interval (CI) 0.076–0.851). …”
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    Valuable prognostic indicators for severe burn sepsis with inhalation lesion: age, platelet count, and procalcitonin
  14. 80814
    “…We found that the PD-1/PD-L1 inhibitor was associated with a 31% reduction in the risk of death (hazard ratio [HR]=0.69; 95% CI 0.64–0.74; P<0.00001) for patients with melanoma, non-small-cell lung cancer (NSCLC), urothelial carcinoma, head and neck carcinoma, and renal cell carcinoma. …”
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    Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis
  15. 80815
    “…With regard to treatment, 40% of patients received trimethoprim-sulfamethoxazole at doses that were lower than recommended, and these patients had a higher mortality risk (HR 1.80 (95% CI 1.10–3.44), p = 0.02). CONCLUSIONS: PcP remains a life-threatening disease among immunocompromised patients. …”
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    Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years
  16. 80816
    por Zhang, Rui, Chen, Xueli, Xiao, Yan
    Publicado 2018
    “…Compared with groups E and F, both HR and mean arterial pressure (MAP) in group FE were significantly decreased from T6 to T10 (P <.05). …”
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    The effects of a forced-air warming system plus electric blanket for elderly patients undergoing transurethral resection of the prostate: A randomized controlled trial
  17. 80817
    “…In multivariable analysis (Figure 3), the risk of VZV reactivation in HT recipients after 12 months (47 patients) was associated with CMV infection before 12 months (HR [95% CI] = 4.74 [1.67–13.47]). Postherpetic neuralgia (PHN) occurred in 23/49 (47%), recurrence in 3/49 (6%), and other complications in 11/49 (22%). …”
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    1554. Reactivation of Varicella Zoster Virus in Solid Organ Transplant Recipients: Identification of Risk Factors Using Data Mining Tools
  18. 80818
    “…In the current work, we performed an intensive PK simulation (n = 10,000 patients) to determine the accuracy of sparse blood sampling in identifying HIV/TB patients with low PZA blood levels, as defined by the AUC in a dosing interval (AUC(0-24)) predictive of successful outcome (363 mg*hr/L). PZA dosing followed WHO guidelines with weight-based dosing bands. …”
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    788. Therapeutic Drug Monitoring for Pyrazinamide During Tuberculosis Treatment: What Is the Diagnostic Accuracy?
  19. 80819
    “…No clinically significant effects on any of the cardiac parameters tested (RR, QRS, HR) were observed. RZF was generally well tolerated. …”
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    2389. Effect of Rezafungin on QT Interval in Healthy Subjects
  20. 80820
    “…In comparison with PreV, PostVcases were older (3 vs. 9 months; P < 0.001), required less hospitalization (87% vs. 68%; P < 0.001), HR (22.3 vs. 10.9; P < 0.001) and LR (6.8% vs. 0%; P = 0.03) decreased and had a higher proportion of complete primary vaccination schedule (44% vs. 11%, P < 0.001). …”
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    2277. Whooping Cough: Epidemiological Changes After Tdap Maternal Immunization Strategy in a Pediatric Hospital
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