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80941por Beydoun, May A., Obhi, Hardeep K., Weiss, Jordan, Canas, Jose A., Beydoun, Hind A., Evans, Michele K., Zonderman, Alan B.“…Finally, baseline ICS was positively associated with incident “elevated depressive symptoms” (EDS: CES-D(total) ≥ 16) among AA (HR = 1.28, 95% CI: 1.04–1.56, P = 0.017). Overall, systemic inflammation was directly linked to increased depressive symptoms over time and at baseline, differentially across sex and race groups. …”
Publicado 2019
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80942por Sato, Naoki, Nakamura, Yuya, Yamadera, Shiho, Inagaki, Masahiro, Kenmotsu, Sachiyo, Saito, Hiroshi, Oguchi, Tatsunori, Tsuji, Mayumi, Chokki, Hirokazu, Ohsawa, Isao, Gotoh, Hiromichi, Iwai, Shinichi, Kiuchi, Yuji“…After 48 hrs of culture, we replaced the medium and pretreated the cells with 100, 250, 500, or 2500 nM linagliptin for 1 hr. We exchanged the medium again, and the cells were treated with 1 ng/mL LPS with or without 100, 250, 500, or 2500 nM linagliptin. …”
Publicado 2019
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80943por Ruan, Jie, Ping, Cai-Yan, Sun, Shuo, Cheng, Xin, Han, Peng-Yu, Zhang, Yin-Ge, Sun, Dian-Xing“…Consequently, the replication-competent HBV vectors carrying foreign genes, including pCH-BsdR, carrying blasticidin resistance gene (399 bp), and pCH-hrGFP, carrying humanized renilla green fluorescent protein gene (720 bp), were successfully obtained. …”
Publicado 2019
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80944“…COX survival analysis showed that lymph node metastasis might be an independent factor affecting postoperative recurrence (hazard risk [HR] = 0.240; 95% confidence interval [CI] = 0.968–30.156; P = 0.034). …”
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80945“…Compared to controls, gastrointestinal adverse events with tapentadol PR treatment were reduced; aHR = 0.532 (0.402–0.703; p < 0.001) versus morphine CR and 0.517 (0.363–0.735; p < 0.001) versus oxycodone CR. …”
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80946por Conte, Giulio, Belhassen, Bernard, Lambiase, Pier, Ciconte, Giuseppe, de Asmundis, Carlo, Arbelo, Elena, Schaer, Beat, Frontera, Antonio, Burri, Haran, Calo’, Leonardo, Letsas, Kostantinos P, Leyva, Francisco, Porter, Bradley, Saenen, Johan, Zacà, Valerio, Berne, Paola, Ammann, Peter, Zardini, Marco, Luani, Blerim, Rordorf, Roberto, Sarquella Brugada, Georgia, Medeiros-Domingo, Argelia, Geller, Johann-Christoph, de Potter, Tom, Stokke, Mathis K, Márquez, Manlio F, Michowitz, Yoav, Honarbakhsh, Shohreh, Conti, Manuel, Sticherling, Christian, Martino, Annamaria, Zegard, Abbasin, Özkartal, Tardu, Caputo, Maria Luce, Regoli, François, Braun-Dullaeus, Rüdiger C, Notarangelo, Francesca, Moccetti, Tiziano, Casu, Gavino, Rinaldi, Christopher A, Levinstein, Moises, Haugaa, Kristina H, Derval, Nicolas, Klersy, Catherine, Curti, Moreno, Pappone, Carlo, Heidbuchel, Hein, Brugada, Josép, Haïssaguerre, Michel, Brugada, Pedro, Auricchio, Angelo“…Age ≤16 years at the time of the first ventricular arrhythmia was the only predictor of arrhythmic recurrence on multivariable analysis [hazard ratio (HR) 0.41, 95% confidence interval (CI) 0.18–0.92; P = 0.03]. …”
Publicado 2019
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80947por Jiang, Lianxiang, Qiu, Shulin, Zhang, Peng, Yao, Weidong, Chang, Yan, Dai, Zeping“…Between the groups, the rates of hoarseness or sore throat, minor injury, hypoxemia and changes in SBP and HR showed no significant difference (P > 0.05). …”
Publicado 2019
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80948por Shieh, Eugenie, Marzinke, Mark A, Fuchs, Edward J, Hamlin, Allyson, Bakshi, Rahul, Aung, Wutyi, Breakey, Jennifer, Poteat, Tonia, Brown, Todd, Bumpus, Namandjé N, Hendrix, Craig W“…RESULTS: Plasma TFV and FTC C(24) (trough) concentrations in TGW were lower by 32% (p = 0.010) and 32% (p = 0.038) respectively, when compared to CGM. Plasma TFV and FTC 24‐hr area under the concentration‐time curve in TGW trended toward and was significantly lower by 27% (p = 0.065) and 24% (p = 0.028) respectively. …”
Publicado 2019
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80949por Capkun, Gorana, Schmidt, Jens, Ghosh, Shubhro, Sharma, Harsh, Obadia, Thomas, de Vera, Ana, Risson, Valery, Amzal, Billy“…Based on the Bayesian survival model, among all candidate variables, presence of dysphagia and decrease in 6MWD [m] were associated with poorer survival with contributing hazard ratios (HR) 1.61 (95% credible interval [CrI]: 0.84–3.50) and 2.48 (95% CrI: 1.27–5.00) respectively. …”
Publicado 2019
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80950por Gofrit, Ofer N., Klein, Benjamin Y., Cohen, Irun R., Ben-Hur, Tamir, Greenblatt, Charles L., Bercovier, Hervé“…The Cox proportional hazards regression model and the Kaplan-Meier analysis of AD free survival both indicated high significance: patients not treated with BCG had a significantly higher risk of developing AD compared to BCG treated patients (HR 4.778, 95%CI: 2.837–8.046, p = 4.08x10(-9) and Log Rank Chi-square 42.438, df = 1, p = 7.30x10(-11), respectively). …”
Publicado 2019
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80951“…Patients with SpO2>85%, stable hemodynamics (HR and BP change <20%), stable respiration (RR change <50%), and the absence of (i) signs of labored breathing, (ii) emergence or worsened discomfort, (iii) change in mental status, were labeled as successful in bearing the SBT. …”
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80952por Hassanen, Eman I, Tohamy, AF, Issa, Marwa Y, Ibrahim, Marwa A, Farroh, Khaled Y, Hassan, Azza M“…STUDY DESIGN: 37 nm sized CuO-NPs were prepared by precipitation method and characterized by using X-ray diffractometer (XRD), Zetasizer nano-and high-resolution transmission electron microscope (HR-TEM). 30 Wistar rats were partitioned into 6 equal groups as follows: Group 1 (negative control), groups 2 & 3 (PJ control groups), group 4 (CuO-NPs group), groups 5 & 6 (CuO-NPs + PJ groups). …”
Publicado 2019
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80953por Piazzese, Concetta, Foley, Kieran, Whybra, Philip, Hurt, Chris, Crosby, Tom, Spezi, Emiliano“…A Cox regression model constructed using 5 clinical variables (age, sex, tumour, node and metastasis (TNM) stage, WHO performance status and contrast administration) and 4 radiomic variables (inverse variance(GLCM), large distance emphasis(GLDZM), zone distance non uniformity norm(GLDZM), zone distance variance(GLDZM)), identified one radiomic feature (zone distance variance(GLDZM)) that was significantly associated with overall survival (p-value = 0.032, HR = 1.25, 95% CI = 1.02–1.52). A significant difference in overall survival between groups was found when considering a threshold of zone distance variance(GLDZM) equals to 1.70 (X(2) = 7.692, df = 1, p-value = 0.006). …”
Publicado 2019
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80954por Rogers, Zora R., Nakano, Taizo A., Olson, Timothy S., Bertuch, Alison A., Wang, Winfred, Gillio, Alfred, Coates, Thomas D., Chawla, Anjulika, Castillo, Paul, Kurre, Peter, Gamper, Christopher, Bennett, Carolyn M., Joshi, Sarita, Geddis, Amy E., Boklan, Jessica, Nalepa, Grzegorz, Rothman, Jennifer A., Huang, James N., Kupfer, Gary M., Cada, Michaela, Glader, Bertil, Walkovich, Kelly J., Thompson, Alexis A., Hanna, Rabi, Vlachos, Adrianna, Malsch, Maggie, Weller, Edie A., Williams, David A., Shimamura, Akiko“…For relapsed/refractory disease, treatment with a hematopoietic stem cell transplant had a superior event-free survival compared to second immunosuppressive therapy treatment in a multivariate analysis (HR=0.19, 95%CI: 0.08,0.47; P=0.0003). This study highlights the need for improved therapies to achieve sustained high-quality remission for children with severe aplastic anemia.…”
Publicado 2019
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80955por Shoji, Satoshi, Hosojima, Michihiro, Kabasawa, Hideyuki, Kondo, Rie, Miura, Satoru, Watanabe, Satoshi, Aoki, Nobumasa, Kaseda, Ryohei, Kuwahara, Shoji, Tanabe, Naohito, Hirayama, Yoshiaki, Narita, Ichiei, Kikuchi, Toshiaki, Kagamu, Hiroshi, Saito, Akihiko“…In addition, according to the hazard ratios (HRs) for eGFR decline > 10 mL/min/1.73 m(2) calculated using a Cox proportional hazard model, the highest quartile had a significantly higher risk of eGFR decline compared with the lowest quartile (HR 7.243; 95% confidence interval 1.545–33.962). …”
Publicado 2019
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80956por Benjamens, Stan, Pol, Robert A., Berger, Stefan P., Glaudemans, Andor W. J. M., Dibbets-Schneider, Petra, Slart, Riemer H. J. A., de Geus-Oei, Lioe-Fee“…Multivariate analysis showed a significant association between the qualitative grades, from the first and second scintigraphy, and DGF duration, HR 1.8 (1.4–2.2, p < 0.01) and 2.8 (1.8–4.3, p < 0.01), respectively. …”
Publicado 2019
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80957por Ljubin-Sternak, Sunčanica, Meštrović, Tomislav, Ivković-Jureković, Irena, Kolarić, Branko, Slović, Anamarija, Forčić, Dubravko, Tot, Tatjana, Mijač, Maja, Vraneš, Jasmina“…Most of RV-A sequences formed a distinct phylogenetic group; only strains RI/HR409-18 (along with a reference strain MF978777) clustered with RV-C strains. …”
Publicado 2019
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80958por Singh, Dave, D’Urzo, Anthony D, Donohue, James F, Kerwin, Edward M, Molins, Eduard, Chuecos, Ferran, Ribera, Anna, Jarreta, Diana“…AB/FF showed improvements in 1 hr post-dose FEV(1), trough FEV(1), and patient-reported outcomes versus placebo and monotherapies. …”
Publicado 2019
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80959por Li, Dan, Zhong, Chenhan, Cheng, Yi, Zhu, Ning, Tan, Yinuo, Zhu, Lizhen, Xu, Dong, Yuan, Ying“…Patients with IMPC had a favorable prognosis with statistical significance compared with patients with IDC (overall mortality HR = 0.68; 95%CI, 0.53-0.86; P = 0.002). Based on Gray method, patients with IMPC had a favorable prognosis with significant statistical significance compared with patients with IDC (BCSD SHR = 0.64; 95%CI, 0.47-0.88; P = 0.006). …”
Publicado 2019
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80960por Liu, Minetta C, Janni, Wolfgang, Georgoulias, Vassilis, Yardley, Denise A, Harbeck, Nadia, Wei, Xin, McGovern, Desmond, Beck, Robert“…The median PFS was longer in Group 2 vs Group 1 (8.5 vs 4.7 months; HR, 0.30 [95% CI, 0.17–0.54]). These results were supported by the ≥2- and ≥5-CTC cutoff analyses. …”
Publicado 2019
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