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  1. 81081
    “…Multivariate analysis indicated that tumor location was an independent predictor of DFS (HR = 2.305, 95% CI 1.203–4.417, P = 0.012). CONCLUSION: Tumor location of the rectal cancer significantly affected the clinical and oncological outcomes after laparoscopic surgery, and it was an independent predictor of DFS.…”
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    Influence of tumor location on short- and long-term outcomes after laparoscopic surgery for rectal cancer: a propensity score matched cohort study
  2. 81082
    “…Detection of ctDNA TP53 mutations was associated with a significantly shorter metastasis-free survival (6.2 vs. 9.5 years (HR 2.4; 95% CIs 1.2–4.8, p = 0.014). CONCLUSIONS: CtDNA is uncommonly detected in localised prostate cancer, but its presence portends more rapidly progressive disease.…”
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    Detection of ctDNA in plasma of patients with clinically localised prostate cancer is associated with rapid disease progression
  3. 81083
    “…METHODS: Six-week-old female BALB/c mice were exposed to filtered air or O(3) for 21 days (2 ppm for 3 hr/day). NH(4)Cl (0, 0.1, 1, and 10 mM) was administered intratracheally into the airways. …”
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    Effects of Ammonium Chloride on Ozone-induced Airway Inflammation: the Role of Slc26a4 in the Lungs of Mice
  4. 81084
    “…For prognostic meta-analyses, the pooled HR for terminal events of higher expression of miRNAs and lower expression of miRNAs were 5.68 (95% CI 4.73–6.82, P < 0.05) and 3.78 (95% CI 3.27–4.37, P < 0.05), respectively. …”
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    Serum-Derived microRNAs as Prognostic Biomarkers in Osteosarcoma: A Meta-Analysis
  5. 81085
    “…Higher MPI was associated with a higher mortality risk (adjusted HR 1.56 [95%CI 1.70–2.09] and 1.72 [1.33–2.22] for MPI groups 2 and 3 compared to 1; p < 0.0001). …”
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    Comprehensive geriatric assessment in older patients with cancer: an external validation of the multidimensional prognostic index in a French prospective cohort study
  6. 81086
    “…Overweight women with greater-than-recommended PWG were at increased risk of cessation, although not significantly (aHR [95% CI]: 1.29 [0.95–1.75]). No significant relationship was observed for exclusive breastfeeding cessation. …”
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    Maternal pre-pregnancy body mass index, gestational weight gain and breastfeeding outcomes: a cross-sectional analysis
  7. 81087
    “…Multivariate Cox regression analysis indicated that the non-survival group had higher weight, higher EuroSCORE, more smoking patients, longer time of cardiopulmonary bypass (CPB), more intra-aortic balloon pump (IABP) use, and more patients who always used β-blocker (HR: 2.056, 95%CI:1.236–3.420, P = 0.005) compared with survival group. …”
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    Evaluation of β-blocker therapy for long-term outcomes in patients with low ejection fraction after cardiac surgery
  8. 81088
    “…The univariate Cox analysis indicated that an elevated ratio of E/E’(≥13.45) was the independent predictor for late PAF recurrence (HR = 3.322, 95%CI: 1.560–7.075, P = .002). However, the ratio of E/E’ cut off at 13.25 predicted atrial tachyarrhythmia recurrence with 75% sensitivity and 62.2% specificity. …”
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    The impact of echocardiographic parameter ratio of E/E’ on the late recurrence paroxysmal atrial fibrillation in patients accepted radiofrequency catheter ablation: A retrospective clinical study
  9. 81089
    “…Sex was not associated with the study outcomes (adj. HR 1.48, 95% CI 0.83–2.63), p = 0.18. CONCLUSION: In chronic HFpEF, assessing sex differences in a wide range of circulating proteins led to the identification of 9 proteins that were differentially expressed between female and male patients. …”
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    Sex differences in circulating proteins in heart failure with preserved ejection fraction
  10. 81090
    “…Time to clinical improvment in the IFN group was significantly shorter than the control group ([9(6–10) vs. 11(9–15) days respectively, p = 0.002, HR = 2.30; 95% CI: 1.33–3.39]). At day 14, the percentage of discharged patients was 78.79% and 54.55% in the IFN and control groups respectively (OR = 3.09; 95% CI: 1.05–9.11, p = 0.03). …”
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    Interferon β-1b in treatment of severe COVID-19: A randomized clinical trial
  11. 81091
    “…Median OS was 49.1 vs. 24.1 months (p = 0.147). Hazard ratio (HR) for death was 0.60 (95% CI: 0.30–1.21). At 2 years, PFS was 56% vs. 44%, LC 84% vs. 72%, and MFS 74% vs. 54%. …”
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    Radiochemotherapy with or without cetuximab for unresectable esophageal cancer: final results of a randomized phase 2 trial (LEOPARD-2)
  12. 81092
    “…No evidence of an association was found with maternal or paternal exposure for any of the outcomes, except for “non-CNS solid tumours” (High versus None; Father: adjusted HR [95%CI] =1.84 [1.31–2.58]; Mother: 1.79 [1.13–2.84]). …”
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    Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: a census-based cohort study
  13. 81093
    “…Cox proportional hazards regressions were used to calculate Hazard Ratios (HR) with 95% Confidence Intervals (CI) for the associations between CWP and/or CMDs with DP, unemployment and mortality, while conditional Cox models for twin pairs provided control for familial confounding. …”
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    Adverse outcomes of chronic widespread pain and common mental disorders in individuals with sickness absence – a prospective study of Swedish twins
  14. 81094
    “…However, on multivariate analysis, only Ca19.9 > 37 predicted recurrence (p = 0.002, HR 5.8). CONCLUSIONS: Raised CA19.9 and CEA predict metastatic disease in patients with GBC without jaundice with a high specificity and may help in prognostication of the patient. …”
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    Raised CA19–9 and CEA have prognostic relevance in gallbladder carcinoma
  15. 81095
    “…BaSO(4) with loaded Insulin showed an onset of glucose-lowering action within 1 hr, with blood glucose level measured significantly lower compared to the 2nd and 3rd h (p < 0.05). …”
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    Insulin-Loaded Barium Salt Particles Facilitate Oral Delivery of Insulin in Diabetic Rats
  16. 81096
    “…In contrast, when the meta-analysis was performed restricting only to studies that used appropriate adjustment (e.g., time, disease severity), there was a significant difference between the two groups (HR 0.378, 95% CI 0.221–0.646 in the random effects model, p < 0.0001). …”
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    Efficacy of Corticosteroids in Patients with SARS, MERS and COVID-19: A Systematic Review and Meta-Analysis
  17. 81097
    “…LVEF was associated to the main event in the multivariate analysis (HR 2.09, 95% CI: 1.12–3.89; P=0.02). CONCLUSIONS: The MitraClip edge-to-edge technique is a safe and effective procedure for the treatment of FMR. …”
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    Percutaneous treatment with Mitraclip for functional mitral regurgitation: medium-term follow up according to left ventricular function
  18. 81098
    “…Although in each stratum, the cumulative 1 year incidence of MACEs was significantly higher in patients who underwent revascularisation than in those who did not (SPECT stratum: 9.1 vs 1.2%, log-rank p<0.0001; CT stratum: 6.1 vs 0.8%, log-rank p=0.0001), there was no interaction between the risk of revascularisation and the imaging strata (SPECT stratum: adjusted HR (95% CI), 4.25 (1.86–9.72); CT stratum: 4.13 (1.16–14.73); interaction: p=0.97). …”
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    Association of coronary revascularisation after physician-referred non-invasive diagnostic imaging tests with outcomes in patients with suspected coronary artery disease: a post hoc subgroup analysis
  19. 81099
    “…Adjusted for confounders, a Cox proportional hazard model showed that IPA was associated with increased risk for 60-day mortality [hazard ratio (HR) 4.336, 95% confidence interval (CI) 1.191–15.784, p = 0.026] in FluA-p patients. …”
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    Invasive pulmonary aspergillosis in immunocompetent patients hospitalised with influenza A-related pneumonia: a multicenter retrospective study
  20. 81100
    “…RESULTS: Compared with at admission (T(0)), the SBP, HR, and RR at immediately after giving DEX (T(1)), at the beginning of the examination (T(2)), 5 min after the beginning of the examination (T(3)), 10 min after the beginning of the examination (T(4)), and at the end of the examination (T(5)) in the three groups were all reduced (all P < 0.05), but all were within the clinically normal range. …”
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    Efficacy of different dose of dexmedetomidine combined with remifentanil in colonoscopy: a randomized controlled trial
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