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81261“…Additionally, multivariate Cox regression analysis of OS showed that TC/CC genotype was an independent factor for OS (Hazard ratio (HR)=0.65, P=0.021). Interestingly, mRNA expression analysis suggested that the mRNA expression of KDR in PBMC differed significantly according to rs2071559 genotype status (P<0.001). …”
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81262por Liu, Rebecca, Paz, Mary, Siraj, Layla, Boyd, Taylor, Salamone, Silvia, Lite, Thúy-Lan Võ, Leung, Krystle M., Chirinos, Josue D., Shang, Helen H., Townsend, Matthew J., Rho, Junsung, Ni, Peiyun, Ranganath, Kushi, Violante, April D., Zhao, Zezhou, Silvernale, Casey, Ahmad, Imama, Krasnow, Nira A., Barnett, Erica S., Harisinghani, Mukesh, Kuo, Braden, Black, Katharine E., Staller, Kyle“…Feeding intolerance was independently associated with an increased risk of death (HR 3.32; 95% CI 1.97–5.6). CONCLUSIONS: Feeding intolerance is a frequently encountered complication in critically ill COVID-19 patients in a large tertiary care experience and is associated with poor outcomes.…”
Publicado 2022
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81263por Alzubaidi, Laith, Zhang, Jinglan, Humaidi, Amjad J., Al-Dujaili, Ayad, Duan, Ye, Al-Shamma, Omran, Santamaría, J., Fadhel, Mohammed A., Al-Amidie, Muthana, Farhan, Laith“…It then presents convolutional neural networks (CNNs) which the most utilized DL network type and describes the development of CNNs architectures together with their main features, e.g., starting with the AlexNet network and closing with the High-Resolution network (HR.Net). Finally, we further present the challenges and suggested solutions to help researchers understand the existing research gaps. …”
Publicado 2021
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81264por Mahmood, Reem D., Shaw, Danielle, Descamps, Tine, Zhou, Cong, Morgan, Robert D., Mullamitha, Saifee, Saunders, Mark, Mescallado, Nerissa, Backen, Alison, Morris, Karen, Little, Ross A., Cheung, Susan, Watson, Yvonne, O’Connor, James P. B., Jackson, Alan, Parker, Geoff J. M., Dive, Caroline, Jayson, Gordon C.“…On average, the MRI perfusion/permeability parameter, K(trans), increased in response to cytotoxic chemotherapy from pre-treatment to cycle 2 day 2 and this increase was associated with worse OS (HR 1.099, 95%CI 1.01–1.20, p = 0.025). CONCLUSIONS: In patients diagnosed with colorectal cancer with liver metastases, treatment with standard chemotherapy changes cell- and protein-based biomarkers, although these changes are not associated with survival outcomes. …”
Publicado 2021
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81265por Calling, Susanna, Johansson, Sven-Erik, Wolff, Moa, Sundquist, Jan, Sundquist, Kristina“…RESULTS: Increasing TC/HDL-C as well as non-HDL-C showed strong associations with IHD, with the highest risk in the 5th quintile, where the HR was 2.30 (95% CI: 1.70–3.11) for TC/HDL-C and 1.67 (95% CI: 1.25–2.24) for non-HDL-C, after adjustments. …”
Publicado 2021
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81266por Pilotto, Alberto, Azzini, Margherita, Cella, Alberto, Cenderello, Giovanni, Castagna, Alberto, Pilotto, Andrea, Custureri, Romina, Dini, Simone, Farinella, Sara Tita, Ruotolo, Giovanni, Padovani, Alessandro, Custodero, Carlo, Veronese, Nicola“…In the multivariable analysis, people in MPI 3 experienced a higher risk of in hospital mortality (HR = 6.30, 95%CI: 1.44–27.61), compared to MPI 1. …”
Publicado 2021
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81267por Oh, Jong Jin, Ahn, Hyungwoo, Hwang, Sung Il, Lee, Hak Jong, Choe, Gheeyoung, Lee, Sangchul, Lee, Hakmin, Byun, Seok-Soo, Hong, Sung Kyu“…PI-RADS score was shown to be a significant predictor of significant pathologic Gleason score upgrading (OR = 6.246, p < 0.001) and biochemical recurrence (HR = 2.595, p = 0.043). 10-years biochemical recurrence-free survival was estimated to be 84.4% and 72.6% in the MRI-negative and MRI-positive groups (p = 0.035). …”
Publicado 2021
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81268Increased prevalence of obstructive sleep apnea in women diagnosed with endometrial or breast cancerpor Madut, Ayey, Fuchsova, Veronika, Man, Hong, Askar, Shabeel, Trivedi, Ritu, Elder, Elisabeth, Clarke, Christine L., Wain, Gerard, Brand, Alison, DeFazio, Anna, Amis, Terence, Kairaitis, Kristina“…Apnea-Hypopnea Index (AHI) (BC: 21.2(7.3–36.9) events/hr; EC: 15.7 (10–33.5) events/hour (median (interquartile range)) was not different p = 0.7), however, 58% and 57% of women with BC and EC respectively, had an AHI>15 events/hour. …”
Publicado 2021
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81269por Hermida, Margaux, Preel, Ancelin, Assenat, Eric, Piron, Lauranne, Cassinotto, Christophe, Ursic‐Bedoya, José, Guillot, Chloé, Herrero, Astrid, Panaro, Fabrizio, Pageaux, Georges‐Philippe, Guiu, Boris“…In multivariate analysis, steatotic HCC (hazard ratio = 0.12; P = 0.039) and AFP (HR=1.002; P < 0.001) independently predicted overall survival. …”
Publicado 2020
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81270por de Boer, Anna Z., Bastiaannet, Esther, Putter, Hein, Marang-van de Mheen, Perla J., Siesling, Sabine, de Munck, Linda, de Ligt, Kelly M., Portielje, Johanneke E. A., Liefers, Gerrit Jan, de Glas, Nienke A.“…Besides comorbidities included in the Charlson index, the psychiatric disease was strongly associated with other-cause mortality (sHR 2.44 (95%-CI 1.70–3.50)). The c-statistics of the Charlson index and comorbidity count were similar (0.65 (95%-CI 0.64–0.65) and 0.64 (95%-CI 0.64–0.65)). …”
Publicado 2021
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81271por Ciampi, Quirino, Olivotto, Iacopo, Peteiro, Jesus, D’Alfonso, Maria Grazia, Mori, Fabio, Tassetti, Luigi, Milazzo, Alessandra, Monserrat, Lorenzo, Fernandez, Xusto, Pálinkás, Attila, Pálinkás, Eszter Dalma, Sepp, Róbert, Re, Federica, Cortigiani, Lauro, Tesic, Milorad, Djordjevic-Dikic, Ana, Beleslin, Branko, Losi, Mariangela, Canciello, Grazia, Betocchi, Sandro, Lopes, Luis Rocha, Cruz, Ines, Cotrim, Carlos, Torres, Marco A. R., Bellagamba, Clarissa C. A., Van De Heyning, Caroline M., Varga, Albert, Ágoston, Gergely, Villari, Bruno, Lorenzoni, Valentina, Carpeggiani, Clara, Picano, Eugenio“…During ESE, we assessed left ventricular outflow tract obstruction (LVOTO), stress-induced new regional wall motion abnormalities (RWMA), and HRR (peak/rest heart rate, HR). By selection, all patients completed the follow-up. …”
Publicado 2021
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81272por Jørgensen, Charlotte Levin Tykjær, Larsson, Anna-Maria, Forsare, Carina, Aaltonen, Kristina, Jansson, Sara, Bradshaw, Rachel, Bendahl, Pär-Ola, Rydén, Lisa“…Patients with shifts from the luminal PT to non-luminal DM subtypes had worse progression-free survival compared to patients with a stable subtype (hazard ratio (HR): 2.3; 95% confidence interval (CI): 1.14–4.68, p = 0.02). …”
Publicado 2021
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81273por Bao, Yi, Gu, Chang, Xie, Huikang, Zhao, Shengnan, Xie, Dong, Chen, Chang, Jiang, Gening, Dai, Chenyang, Zhu, Yuming“…Multivariate Cox regression results showed that the high-risk subtype [P=0.012, hazard ratio (HR) =24.560; 95% confidence interval (CI), 2.016–299.227] was a risk factor for postoperative recurrence. …”
Publicado 2021
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81274por Yi, Chengxiang, Dai, Jie, Song, Nan, Wu, Chunxiao, Zhang, Liping, Zhu, Yuming, Jiang, Gening, Zhang, Helin, Zhang, Peng“…Based on the new staging system, adjuvant chemotherapy conferred a significantly better survival in stage-III NETL cases (HR =0.34, 95% CI, 0.25–0.45). CONCLUSIONS: The new pathological staging system can better predict NETL prognosis than the 8(th) edition of the TNM staging system, with the potential to guide postoperative treatment.…”
Publicado 2021
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81275por Liu, Zeming, Liu, Bo, Zhang, Bingshi, Ma, Wenhui, Wu, Tao, Huo, Jia, Liu, Sikai, Han, Yongtai“…The strongest risk factor in this study was intraoperative periprosthetic femoral fracture during revision surgery (HR = 5.477, 95% CI = 2.156–13.913). CONCLUSION: Three risk factors for failure were identified: ageing, osteoporosis and intraoperative periprosthetic femoral fracture during revision surgery. …”
Publicado 2021
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81276por Giaccherini, Matteo, Macauda, Angelica, Orciuolo, Enrico, Rymko, Marcin, Gruenpeter, Karolina, Dumontet, Charles, Raźny, Malgorzata, Moreno, Victor, Buda, Gabriele, Beider, Katia, Varkonyi, Judit, Avet-Loiseau, Hervé, Martinez-Lopez, Joaquín, Marques, Herlander, Watek, Marzena, Sarasquete, Maria Eugenia, Andersen, Vibeke, Karlin, Lionel, Suska, Anna, Kruszewski, Marcin, Abildgaard, Niels, Dudziński, Marek, Butrym, Aleksandra, Nagler, Arnold, Vangsted, Annette Juul, Kadar, Katalin, Waldemar, Tomczak, Jamroziak, Krzysztof, Jacobsen, Svend Erik Hove, Ebbesen, Lene Hyldahl, Taszner, Michał, Mazur, Grzegorz, Lesueur, Fabienne, Pelosini, Matteo, Garcia-Sanz, Ramon, Jurczyszyn, Artur, Demangel, Delphine, Reis, Rui Manuel, Iskierka-Jażdżewska, Elżbieta, Markiewicz, Miroslaw, Gemignani, Federica, Subocz, Edyta, Zawirska, Daria, Druzd-Sitek, Agnieszka, Stępień, Anna, Alonso, M. Henar, Sainz, Juan, Canzian, Federico, Campa, Daniele“…Furthermore, in a subset of 1376 MM patients we tested the relationship between the teloscore and MM patients survival, observing a better prognosis for longer gdTL compared with shorter gdTL (HR = 0.93; 95% CI 0.86–0.99; P = 0.049). In conclusion, we report convincing evidence that longer gdTL is a risk marker for MM risk, and that it is potentially involved in increasing MM survival.…”
Publicado 2021
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81277“…The overall survival (OS) time for the high-risk group was shorter than that for the low-risk group [risk ratio (hazard ratio, HR) = 1.08, 95% CI: 1.06–1.10; p < 0.0001]. Using our model, the defined risk value can predict the prognosis of a patient. …”
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81278por Del Pace, Stefano, Scheggi, Valentina, Virgili, Giacomo, Caciolli, Sabina, Olivotto, Iacopo, Zoppetti, Nicola, Merilli, Irene, Ceschia, Nicole, Andrei, Valentina, Alterini, Bruno, Stefàno, Pier Luigi, Marchionni, Niccolò“…IE relapses at 3 years were associated with the presence of SD (p = 0.003), Staphylococcus aureus infection (p < 0.001), and drug abuse (p < 0.001) but, at multivariable analysis, only drug abuse was an independent predictor of IE relapses (p < 0.001; HR 6.8, 95% CI 1.6–29). At echocardiographic follow-up, SD was not associated with worsening left ventricular systolic function or valvular dysfunction. …”
Publicado 2021
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81279por Liu, Yang, Zhang, Feng-Jiao, Zhao, Xi-Xi, Yang, Yuan, Liang, Chun-Yi, Feng, Li-Li, Wan, Xiang-Bo, Ding, Yi, Zhang, Yao-Wei“…The radiomics model based on high-spatial-resolution T2-weighted imaging (HR-T2WI) and contrast-enhanced T1-weighted imaging (T1+C) demonstrated an area under the curve (AUC) of 0.8910 (0.8114–0.9706) and 0.8938 (0.8084–0.9792), respectively. …”
Publicado 2021
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81280“…However, no association was found between the use of statins and the risk of new-onset dementia (NOD) in patients with RA (HR: 1.01; 95% CI: 0.97–1.06). The subgroup analysis identified the use of statin as having a protective effect against developing NOD in male and older patients. …”
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