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81281“…Pooled analysis of four studies further confirmed the higher risk of recurrence in patients with cystectomy (HR=2.00, 95% CI: 1.11-3.58). In addition, no significant difference in postoperative pregnancy rate was found between patients with the two different surgical procedures (OR=0.92, 95% CI: 0.60-1.42). …”
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81282por Strell, Carina, Stenmark Tullberg, Axel, Jetne Edelmann, Reidunn, Akslen, Lars Andreas, Malmström, Per, Fernö, Mårten, Holmberg, Erik, Östman, Arne, Karlsson, Per“…An increased risk for any recurrence was noted in univariable analysis for the medium (HR 1.58, CI 95% 1.11–2.23, p = 0.011) or PDGFRb high group (1.49, 1.06–2.10, p = 0.021) compared to the low group. …”
Publicado 2021
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81283“…Em < 13 cm/s was significantly associated with pre-eclampsia occurrence (HR 8.56; 95% CI 3.40–21.57) after being adjusted for confounders. …”
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81284por Drakos, Panagiotis, Volteas, Panagiotis, Cleri, Nathaniel A., Alkadaa, Leor N., Asencio, Anthony A., Oganov, Anthony, Pryor, Aurora, Talamini, Mark, Rubano, Jerry, Bannazadeh, Mohsen, Mikell, Charles B., Spaniolas, Konstantinos, Mofakham, Sima“…This was confirmed with multivariable analysis which showed that AGI score III/IV was an independent predictor of higher mortality (AGI III/IV vs AGI 0/I/II hazard ratio (HR), 2.68; 95% confidence interval (CI), 1.69–4.25; P-value <0.0001). …”
Publicado 2021
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81285por Charpentier, Etienne, Soulat, Gilles, Fayol, Antoine, Hernigou, Anne, Livrozet, Marine, Grand, Teodor, Reverdito, Guillaume, al Haddad, Jad, Dang Tran, Kim Diep, Charpentier, Anne, Clement, Olivier, Hulot, Jean-Sebastien, Mousseaux, Elie“…The 30-day mortality increased if vldCTs ≥ 7 (HR, 3.16 (1.50–6.43); p = 0.001), independent of age, respiratory rate and oxygen saturation levels, and comorbidities at admission. …”
Publicado 2021
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81286“…The relationship between lncRNAs expression and survival outcome was estimated by hazard ratio (HR) and 95% confidence interval (CI). Meta-analysis was conducted on the Stata 16.0. …”
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81287“…On arrival, she was Afebrile with a HR 97 beats/minute, a BP of 105/58 mm of Hg and a RR of 17 breaths/minute. …”
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81288por Chu, James W“…Thy+ were compared to Thy- with respect to: mean age (70.7 ± 7.3 vs. 70.8 ± 9.3 y), sex (97% vs. 81% women), 24-hr urine calcium at diagnosis (317 ± 75 vs. 311 ± 68 mg), presence of fragility fracture (50% vs. 59%), use of thiazide (83% vs. 78%), and use of anti-fracture pharmacotherapy (73% vs. 84%). 50 patients had adequate comparative longitudinal BMD data. …”
Publicado 2021
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81289“…Background: Alpelisib, in combination with Fulvestrant, was approved in 2019 by the Food and Drug Administration for treatment of HR+, HER2- advanced or metastatic breast cancer in patients with PIK3CA mutation. a This combination is currently on phase III of study. …”
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81290por Reifsnider, Odette S, Kansal, Anuraag R, Gandhi, Pranav K, Cragin, Lael, Brand, Sarah B, Pfarr, Egon, Fahrbach, Kyle, Ustyugova, Anastasia“…Occurrence of events in EMPA-REG OUTCOME was estimated based on event-free survival curves with time-dependent covariates. An HR for canagliflozin or dapagliflozin versus empagliflozin on each clinical event was estimated from published CANVAS, DECLARE-TIMI 58, and EMPA-REG OUTCOME data using indirect treatment comparison. …”
Publicado 2021
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81291por Zhu, Pengyuan, Gu, Shaorui, Huang, Haitao, Zhong, Chongjun, Liu, Zhenchuan, Zhang, Xin, Wang, Wenli, Xie, Shiliang, Wu, Kaiqin, Lu, Tiancheng, Zhou, Yongxin“…In addition, Cox regression analysis revealed that GNPNAT1 upregulation was significantly associated with poor OS time [hazard ratio (HR): 1.07; 95% confidence interval (CI): 1.04–1.10; P<0.001]. …”
Publicado 2021
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81292“…Participants were followed up for incident cardiovascular outcomes and death over 8 years through linkage to the Swedish National Patient and Death Registers. Hazard ratios (HR) were estimated by Cox proportional hazards regression. …”
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81293“…Patients in dexmedetomidine group received a loading dose dexmedetomidine (0.6 μg/kg in 10 min before anaesthesia induction) followed by a continuous infusion (0.5 μg/kg/hr) till 1 h before the end of surgery. Patients in control group received volume-matched normal saline at the same time interval. …”
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81294por Xu, Guocai, Shi, Yuanyuan, Ling, Xiaoting, Wang, Dongyan, Liu, Yunyun, Lu, Huaiwu, Peng, Yongpai, Zhang, Bingzhong“…Moreover, multivariate analysis identified HHLA2 expression as an independent prognostic factor that predicted improved survival (p = 0.049; HR = 0.156; 95% CI = 0.025–0.992). Additionally, we also found that overexpressing HHLA2 inhibited the proliferation of ovarian cancer cells. …”
Publicado 2021
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81295por Minhas, Anum S., Shade, Julie K., Cho, Sung-Min, Michos, Erin D., Metkus, Thomas, Gilotra, Nisha A., Sharma, Garima, Trayanova, Natalia, Hays, Allison G.“…Despite adjustment for demographics and cardiovascular risk factors, male sex predicted mortality (HR 1.33; 95% CI:1.01–1.74; p = 0.041). While men had significantly higher markers of inflammation, in sex-stratified analyses, increase in interleukin-6, C-reactive protein, ferritin and d-dimer were predictive of mortality and myocardial injury similarly in both sexes. …”
Publicado 2021
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81296por Li, Wenlin, Zhou, Jin, Liu, Shen, Xing, Kaihui, Yang, Ling, Zhong, Lihua, Chen, Qiuli, Zhang, Wei“…When the neonatal 25(OH)D3 was divided into quartiles to perform a categorical variable analysis, we found that compared with the first quantile (Q1, 0.0–25.1 mmol/L), the risk of asthma in Q4 was reduced by 50% (HR=0.50, 95% CI: 0.38-0.76). The second quantile group (Q2) and the third quantile group (Q3) showed no significant difference in the risk of disease compared with Q1 but showed a trend of decreasing risk as the quantile group increased (the trend P values were both <0.05). …”
Publicado 2021
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81297por Coons, James C., Crisamore, Karryn, Adams, Solomon, Modany, Ashley, Simon, Marc A., Zhao, Wenchen, Shaik, Imam H., Venkataramanan, Raman, Empey, Philip E.“…Survival analysis showed that increased CYP2C9 activity score was associated with decreased risk for treatment discontinuation [hazard ratio (HR): 0.13; 95% confidence interval (CI): 0.02, 0.91; p = 0.04]. …”
Publicado 2021
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81298por Besutti, Giulia, Ottone, Marta, Fasano, Tommaso, Pattacini, Pierpaolo, Iotti, Valentina, Spaggiari, Lucia, Bonacini, Riccardo, Nitrosi, Andrea, Bonelli, Efrem, Canovi, Simone, Colla, Rossana, Zerbini, Alessandro, Massari, Marco, Lattuada, Ivana, Ferrari, Anna Maria, Giorgi Rossi, Paolo“…CT disease extension was also independently associated with death (HR = 7.56, 95% CI = 3.49; 16.38 for ≥ 60% extension). cvAUCs were 0.927 (bootstrap bias-corrected 95% CI = 0.899–0.947) for the clinical model and 0.936 (bootstrap bias-corrected 95% CI = 0.912–0.953) when adding CT extension. …”
Publicado 2021
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81299por Linhares, Kamilla, Taddeo, Julia Bernardi, Cristelli, Marina Pontello, Proença, Henrique, Ficher, Klaus Nunes, de Marco, Renato, Gerbase-DeLima, Maria, Medina-Pestana, Jose, Tedesco-Silva, Helio“…There was no difference in the cumulative incidence of efficacy failure (18.0% vs. 21.8%, HR = 1.22, 95% CI 0.66–2.25), respectively. There were no differences in 3-years freedom from biopsy proven acute rejection, and patient, graft, and death-censored graft survivals. …”
Publicado 2021
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81300por Schiele, Stefan, Arndt, Tim Tobias, Martin, Benedikt, Miller, Silvia, Bauer, Svenja, Banner, Bettina Monika, Brendel, Eva-Maria, Schenkirsch, Gerhard, Anthuber, Matthias, Huss, Ralf, Märkl, Bruno, Müller, Gernot“…A multivariable Cox regression analysis adjusted for confounders supported the use of risk groups as a prognostic factor for the occurrence of metastasis (hazard ratio (HR): 5.4, 95% CI: 2.5–11.7, p < 0.001). BIg-CoMet achieved good performance for both UICC subgroups, especially for UICC III (n = 53), with a positive predictive value of 80%. …”
Publicado 2021
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