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81301por Debeb, Simachew Gidey, Muche, Achenef Asmamaw, Kifle, Zemene Demelash, Sema, Faisel Dula“…Adult PLHIV taking TDF-based regimens were 1.70 (adjusted HR = 1.70; 95% CI = 1.02–2.82) times at higher risk of renal dysfunction than non-TDF-based regimens. …”
Publicado 2021
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81302por Heiblig, Maël, Duployez, Nicolas, Marceau, Alice, Lebon, Delphine, Goursaud, Laure, Plantier, Isabelle, Stalnikiewich, Laure, Cambier, Nathalie, Balsat, Marie, Fossard, Gaëlle, Labussière-Wallet, Hélène, Barraco, Fiorenza, Ducastelle-Lepretre, Sophie, Sujobert, Pierre, Huet, Sarah, Hayette, Sandrine, Ghesquières, Hervé, Thomas, Xavier, Preudhomme, Claude“…DNMT3A negative patients who reached a 4log reduction had a superior outcome to those who did not (HR = 0.23; p < 0.001). However, postinduction NPM1 MRD1 reduction was not predictive of OS and LFS in DNMT3Amut patients. …”
Publicado 2021
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81303“…In the Cox multiple regression model, after adjusting the model according to important risk factors, the AAPR and NAFLD risk were independently correlated, and with a gradual increase in the AAPR, the NAFLD risk decreased gradually (HR: 0.61, 95% CI: 0.47, 0.81; P-trend< 0.0001). …”
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81304por Ao, Guangyu, Wang, Yushu, Qi, Xin, Nasr, Basma, Bao, Mulong, Gao, Ming, Sun, Ying, Xie, Dili“…Moreover, pooled analysis of adjusted results revealed that SOT recipients had a greater risk of mortality compared with non-SOT patients (HR = 1.54, 95%CI: 1.03 to 2.32, P = 0.037). LIMITATIONS: The main limitations in our study are attributed to the relatively small sample size, short follow-up period, and the fact that most of the studies included were retrospective in design. …”
Publicado 2021
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81305por Kapoor, Indu, Wanchoo, Jaya, Mahajan, Charu, Singhal, Vasudha, Roy, Hirok, Kumar, Subodh, Brahma, Rupali, Prasad, Chandrakant, Kalaivani, Mani, Prabhakar, Hemanshu, Chaturvedi, Arvind“…We assessed mean values of ONSD, HR, MBP, and SpO(2) for changes over various time points during PCT using generalized estimating equation (GEE). …”
Publicado 2021
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81306por Howe, Christopher C. F., Swann, Nicola, Spendiff, Owen, Kosciuk, Anna, Pummell, Elizabeth K. L., Moir, Hannah J.“…There were significant increases in [Formula: see text] O(2), Cr, F, [Formula: see text] (E) and heart rate (HR) (p < 0.01); a significant decrease in RER (p < 0.01) and no change in SL and SPM (p > 0.05) across the measured timepoints. …”
Publicado 2021
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81307por Shen, Xiaonan, Li, Jialu, Li, Jiaqi, Zhang, Yao, Li, Xiaobo, Cui, Yun, Gao, Qinyan, Chen, Xiaoyu, Chen, Yingxuan, Fang, Jing-Yuan“…The high abundance of P. stomatis was related to the adenoma recurrence after LST resection (HR = 3.88, P = 0.008). CONCLUSIONS: Fecal microbiome signature (ETBF–P. stomatis–P. micra) can diagnose LSTs with high accuracy. …”
Publicado 2021
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81308por Chen, Huihui, Wu, Shijie, Hu, Jun, Zhang, Kun, Hu, Kaimin, Lu, Yuexin, He, Jiapan, Pan, Tao, Chen, Yiding“…According to tumor marker risk scores (TMRS) computed by the lasso Cox model, the high TMRS group had worse DFS (HR = 3.138, 95% CI: 1.711–5.033, p < 0.0001) and OS (3.983, 1.637–7.214, p=0.0011) than low TMRS group. …”
Publicado 2021
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81309por Gyoten, Takayuki, Morshuis, Michiel, Rojas, Sebastian V., Deutsch, Marcus-André, Schramm, René, Gummert, Jan F., Fox, Henrik“…Multiple Cox regression model analysis revealed time interval between HVAD implantation and first thrombosis as an independent risk factor of recurrent thrombosis (HR, 0.93, 95% CI 0.87–0.99, p = 0.031). Kaplan–Meier analysis at 3 year follow-up showed no significant difference in overall survival for recurrent vs non-recurrent thrombosis groups (log-rank test, p = 0.959). …”
Publicado 2020
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81310por Kelly, Benjamin, Innes, Aidan, Holl, Marc, Mould, Laura, Powell, Susan, Burns, Danielle, Doherty, Patrick, Whyte, Greg, King, James, Deniszczyc, Davina“…Primary outcome measures will assess changes in health-related quality of life (HR-QOL) and COVID-19 symptoms using EuroQol Five Dimension Five Level Version (EQ-5D-5L) and Dyspnea-12, respectively. …”
Publicado 2021
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81311por Mao, Ziling, Zhang, Weihao, Wu, Chunyin, Feng, Hao, Peng, Yuanhang, Shahid, Hamza, Cui, Zining, Ding, Ping, Shan, Tijiang“…The structures of these compounds were elucidated by analysis of 1D and 2D NMR and HR-ESI-MS spectra and a comparison of their spectral data with published values. …”
Publicado 2021
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81312por Dąbrowska-Balcerzak, Karolina, Nartowska, Jadwiga, Wawer, Iwona, Siudem, Paweł, Paradowska, Katarzyna“…The structures of those compounds were determined by NMR spectroscopy, including 2D COSY, HMBC, HSQC, NOESY, ROESY experiments, theoretical calculations of shielding constants by GIAO DFT, and mass spectrometry (FAB/LSI HR MS). An attempt was made to test biological activity, particularly as potential chemotherapeutic agents, using in silico methods. …”
Publicado 2021
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81313por Pagnesi, Matteo, Inciardi, Riccardo M., Lombardi, Carlo M., Agostoni, Piergiuseppe, Ameri, Pietro, Barbieri, Lucia, Bellasi, Antonio, Camporotondo, Rita, Canale, Claudia, Carubelli, Valentina, Carugo, Stefano, Catagnano, Francesco, Dalla Vecchia, Laura A., Danzi, Gian Battista, Di Pasquale, Mattia, Gaudenzi, Margherita, Giovinazzo, Stefano, Gnecchi, Massimiliano, Guazzi, Marco, Iorio, Annamaria, La Rovere, Maria Teresa, Leonardi, Sergio, Maccagni, Gloria, Mapelli, Massimo, Margonato, Davide, Merlo, Marco, Monzo, Luca, Mortara, Andrea, Nuzzi, Vincenzo, Piepoli, Massimo, Porto, Italo, Pozzi, Andrea, Sarullo, Filippo, Sinagra, Gianfranco, Tedino, Chiara, Tomasoni, Daniela, Volterrani, Maurizio, Zaccone, Gregorio, Senni, Michele, Metra, Marco“…After adjustment for relevant covariates, use of glucocorticoids was associated with a lower risk of in-hospital mortality (adjusted HR 0.44; 95% CI 0.26–0.72; p = 0.001). A significant interaction was observed between the protective effect of glucocorticoids on mortality and PaO(2)/FiO(2) ratio on admission (p = 0.042), oxygen saturation on admission (p = 0.017), and peak CRP (0.023). …”
Publicado 2021
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81314por Aczon, Melissa D., Ledbetter, David R., Laksana, Eugene, Ho, Long V., Wetzel, Randall C.“…MEASUREMENTS AND MAIN RESULTS: On 2,475 test set episodes lasting greater than or equal to 24 hours in the PICU, the area under the receiver operating characteristic curve of the recurrent neural network’s 12th hour predictions was 0.94 (CI, 0.93–0.95), higher than those of Pediatric Index of Mortality 2 (0.88; CI, [0.85–0.91]; p < 0.02), Pediatric Risk of Mortality III (12th hr) (0.89; CI, [0.86–0.92]; p < 0.05), and Pediatric Logistic Organ Dysfunction day 1 (0.85; [0.81–0.89]; p < 0.002). …”
Publicado 2021
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81315por Nakajima, Tadashi, Dharmawan, Tommy, Kawabata‐Iwakawa, Reika, Tamura, Shuntaro, Hasegawa, Hiroshi, Kobari, Takashi, Ota, Masaki, Tange, Shoichi, Nishiyama, Masahiko, Kaneko, Yoshiaki, Kurabayashi, Masahiko“…After incubation of transfected cells with or without 0.1 mM MEX for 24–36 hr, whole‐cell sodium currents (I(Na)) were recorded using patch‐clamp techniques. …”
Publicado 2021
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81316“…Propensity score matching (PSM) was used to balance the differences between young and old groups. Hazard ratio (HR) was applied to evaluate prognostic risk of age in different subgroups. …”
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81317por Ito, Tomoko, Mori, Takahiro, Takahashi, Hideto, Shimafuji, Natsumi, Iijima, Katsuya, Yoshie, Satoru, Tamiya, Nanako“…In our sub-analysis, the preventive service was effective in avoiding deteriorations only among those aged 85 and older with support level 1 (HR 0.65, 95% CI 0.43–0.97) out of four groups. CONCLUSIONS: The preventive services of LTCI in Kashiwa City showed a significant effect on the deterioration among subjects aged 85 or older, whose disability level were low (support level 1). …”
Publicado 2021
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81318por Li, Qianqian, Ding, Xiao, Liu, Yujie, Marcella, Cicilia, Dai, Min, Zhang, Ting, Bai, Jianling, Xiang, Liyuan, Wen, Quan, Cui, Bota, Zhang, Faming“…Compared with those of 19 patients who achieved clinical remission at one month after FMT, the rates of clinical relapse were significantly higher in 18 patients who achieved clinical remission at one month after IFX [log-rank test p = 0.0009 HR = 3.081 (95% CI 1.43–6.639)]. Multivariate analysis revealed that the gender of donor (95% CI: 0.001–0.72; p = 0.031) was an independent predictor of efficacy at one year after FMT. …”
Publicado 2021
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81319por Worawichawong, Suchin, Plumworasawat, Sirithep, Liwlompaisan, Wisit, Sumethkul, Vasant, Phakdeekitcharoen, Bunyong, Udomsubpayakul, Umaporn, Chalermsanyakorn, Panus, Kitiyakara, Chagriya“…By multivariate analysis, proteinuria, T1, T2 and C4d+ve were independent predictors (Model 2 HR (95% CI) C4d+ve: 3.24 (1.09–9.58), p = 0.034). …”
Publicado 2021
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81320por Weissinger, Eva M., Metzger, Jochen, Schleuning, Michael, Schmid, Christoph, Messinger, Diethelm, Beutel, Gernot, Wagner-Drouet, Eva-Maria, Schetelig, Johannes, Baurmann, Herrad, Rank, Andreas, Stolzl, Friedrich, Schäfer-Eckart, Kerstin, Westphal, Karin, Bethge, Wolfgang, von Harsdorf, S., Bunjes, Donald W., Heidenreich, Daniela, Klein, Stefan, Holler, Ernst, Kreipe, Hans H., Jonigk, Danny, Türüchanow, Irina, Raad, Julia, Papkalla, Armin, von der Leyen, Heiko, Hambach, Lothar, Hamwi, Iyas, Ehrlich, Steve, Krauter, Jurgen, Stadler, Michael, Ganser, Arnold“…Analysis of the short-term preemptive prednisolone therapy in the randomized patients showed no significant difference in incidence or severity of acute GvHD (HR: 1.69, 95% CI: 0.66–4.32, P = 0.27). Prednisolone as preemptive treatment did not lead to an increase in relapse (20.2% in the placebo and 14.0% in the prednisolone group (P = 0.46)). …”
Publicado 2020
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