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81441“…Finally, multivariate Cox regression analysis identified eight prognostic DEIRGs and established a new prognostic signature (HR: 2.49, 95% CI: 1.68–3.67; P<0.001). Based on the expression of the eight genes, the cohort was then divided into high and low risk groups and Kaplan-Meier (K-M) curves were plotted with the log-rank test P<0.0001 and 1-, 3-year area under the curve (AUC) >0.7. …”
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81442por Boeddha, Navin P., Driessen, Gertjan J., Hagedoorn, Nienke N., Kohlfuerst, Daniela S., Hoggart, Clive J., van Rijswijk, Angelique L., Ekinci, Ebru, Priem, Debby, Schlapbach, Luregn J., Herberg, Jethro A., de Groot, Ronald, Anderson, Suzanne T., Fink, Colin G., Carrol, Enitan D., van der Flier, Michiel, Martinón-Torres, Federico, Levin, Michael, Leebeek, Frank W., Zenz, Werner, de Maat, Moniek P. M., Hazelzet, Jan A., Emonts, Marieke, Dik, Willem A.“…Cohort 2 includes patients from a multicenter study involving children admitted to the hospital with invasive bacterial infections of differing etiologies (samples obtained within 48 hr after hospital admission). MAIN OUTCOMES AND MEASURES: Primary outcome measure was mortality. …”
Publicado 2021
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81443“…IL-1RA levels were associated with incident MetS (n = 109) in PIVUS during a 5-year follow-up (HR 1.76 for a 1 SD change (95% CI 1.38, 2.24), p = 4.3*10(–6)). …”
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81444por Kerbert, Annarein J.C., Gupta, Saurabh, Alabsawy, Eman, Dobler, Iwona, Lønsmann, Ida, Hall, Andrew, Nielsen, Signe Holm, Nielsen, Mette J., Gronbaek, Henning, Amoros, Àlex, Yeung, Dave, Macnaughtan, Jane, Mookerjee, Rajeshwar P., Macdonald, Stewart, Andreola, Fausto, Moreau, Richard, Arroyo, Vicente, Angeli, Paolo, Leeming, Diana J., Treem, William, Karsdal, Morten A., Jalan, Rajiv“…Only PRO-C6 was associated with extrahepatic organ failures and 28- and 90-day mortality (hazard ratio [HR; on log-scale] 6.168, 95% CI 2.366–16.080, p <0.001, and 3.495, 95% CI 1.509–8.093, p = 0.003, respectively). …”
Publicado 2021
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81445“…Compared with patients in non-dobutamine group, patients in dobutamine group had a lower MAP, higher HR, higher RR, higher severity of illness scores. 72 of 121 patients (59.5%) in the dobutamine group and 754 of 2165 patients (34.8%) in the non-dobutamine group died in the hospital, which resulted in a significant between-group difference (OR 1.56, 95% CI 1.01–2.40; P = 0.000). …”
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81446por van Doorn, Diederick J., Hendriks, Pim, Burgmans, Mark C., Rietbergen, Daphne D. D., Coenraad, Minneke J., van Delden, Otto M., Bennink, Roel J., Labeur, Tim A., Klümpen, Heinz-Josef, Eskens, Ferry A. L. M., Moelker, Adriaan, Vegt, Erik, Sprengers, Dave, Mostafavi, Nahid, Ijzermans, Jan, Takkenberg, R. Bart“…The ALBI score was an independent predictor of liver decompensation (OR 0.07) and OS (HR 2.83). After SIRT, liver decompensation CP ≥ B7 often developed as a late complication in HCC patients and was associated with a shorter OS. …”
Publicado 2021
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81447por Liu, Ya, Liu, Fubin, Zhang, Liwen, Li, Junxian, Kang, Wenjuan, Cao, Mingli, Song, Fangfang, Song, Fengju“…In the age-adjusted model (model 1), it was found that the lowest LDL-C group had a higher risk of all-cause mortality (HR 1.708 [1.432–2.037]) than LDL-C 100–129 mg/dL as a reference group. …”
Publicado 2021
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81448por Hah, Jennifer M., Nwaneshiudu, Chinwe A., Cramer, Eric M., Carroll, Ian R., Curtin, Catherine M.“…Every one-point increase in the average pain score was associated with a 36.0% reduced rate of pain cessation (HR, 0.64, 95% CI 0.55–0.74, p < 0.001). Average pain on POD 10 was significantly associated with the development of CPSP at 90 days (OR 1.74, 95% CI 1.30–2.33, p value < 0.001). …”
Publicado 2021
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81449“…The time elapsed until reaching a BIS level of 75, propofol infusion dose used during sedation, and the need for additional doses of propofol, heart rate (HR), and duration of post-anesthesia care unit stay were significantly positively correlated with both preoperative anxiety and preoperative pain sensitivity. …”
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81450“…Multivariate Cox proportional risk regression analysis demonstrated that risk score was an independent prognostic factor [hazard ratio (HR) = 1.798, 95% confidence interval (CI) =1.410–2.291, P < 0.001]. …”
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81451por Kamarajah, Sivesh K., Phillips, Alexander W., Griffiths, Ewen A., Ferri, Lorenzo, Hofstetter, Wayne L., Markar, Sheraz R.“…After matching, gastrectomy was associated with significantly reduced survival compared with esophagectomy (median, 51 vs. 68 months [p < 0.001]; 5-year survival, 47 % vs. 53 %), which remained in the adjusted analyses (hazard ratio [HR], 1.22; 95 % confidence interval [CI], 1.09–1.35; p < 0.001). …”
Publicado 2021
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81452por Bakkers, C., Lurvink, R. J., Rijken, A., Nienhuijs, S. W., Kok, N. F., Creemers, G. J., Verhoef, C., Lemmens, V. E., van Erning, F. N., De Hingh, I. H.“…After multivariable correction, OS no longer differed between the patients with synchronous CPM and those with metachronous CPM (HR 1.03 [0.83–1.27]). The patients with metachronous CPM more often underwent CRS-HIPEC than the patients with synchronous CPM (16 % vs 8 %; p = 0.001). …”
Publicado 2021
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81453por Ravegnini, Gloria, De Leo, Antonio, Coada, Camelia, Gorini, Francesca, de Biase, Dario, Ceccarelli, Claudio, Dondi, Giulia, Tesei, Marco, De Crescenzo, Eugenia, Santini, Donatella, Corradini, Angelo Gianluca, Tallini, Giovanni, Hrelia, Patrizia, De Iaco, Pierandrea, Angelini, Sabrina, Perrone, Anna Myriam“…Moreover, in a multivariate analysis, combination of wild type CTNNB1 status and high miR-499a-5p expression was indipendently associated with high risk of death [HR (95%CI): 3.53 (1.1-10.5), p = 0.02]. CONCLUSION: Our results suggest that the combination of CTNNB1 status and miR-499a-5p allows a better stratification of NSMP patients and could promote a personalization of the treatment in intermediate-risk patients.…”
Publicado 2021
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81454por La Porta, Edoardo, Conversano, Ester, Zugna, Daniela, Camilla, Roberta, Labbadia, Raffaella, Paglialonga, Fabio, Parolin, Mattia, Vidal, Enrico, Verrina, Enrico“…As compared to patients on HD, those treated with PD exhibited increased but non-significant mortality risk (HR 2.15 [95%CI 0.54–8.6]; p = 0.28) and higher prevalence of dialysis-related complications during DAGF (p = 0.002) CONCLUSIONS: Patients entering DAGF in more recent years are more likely to be initiated on HD. …”
Publicado 2021
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81455por Otterstad, Jan Erik, Norum, Ingvild Billehaug, Ruddox, Vidar, Le, An Chau Maria, Bendz, Bjørn, Munkhaugen, John, Klungsøyr, Ole, Edvardsen, Thor“…In adjusted Cox regression analyses, baseline GLS was associated with all recurrent CCVE (HR 1.1, 95% CI 1.0 to 1.2, p < 0.001) whereas non-improvement versus improvement over 3 months follow-up was not. …”
Publicado 2021
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81456por Yang, Hui, Sun, Shaoxing, Mei, Zijie, Xiang, Qingming, Yang, Chunxu, Chen, Min, Xie, Conghua, Zhou, Yunfeng, Qiu, Hui“…Moreover, the patients treated with anlotinib had better survival with a significantly lower cumulative incidence of cancer-related death than those treated with apatinib (HR=0.31, 95% CI: 0.13–0.77, p=0.012). The most common adverse effects in the patients treated with anlotinib were hypertension (20%), fatigue (20%), and nausea (15%). …”
Publicado 2021
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81457por Pereira-Rodriguez, J. A., Bravo-Salva, A., Montcusí-Ventura, B., Hernández-Granados, P., Rodrigues-Gonçalves, V., López-Cano, M.“…Operations performed in a non-specialized unit were significantly associated with recurrences (HR 4.903, CI 1.64–14.65; P = 0.004). CONCLUSION: CST is a complex procedure with a high rate of complications. …”
Publicado 2021
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81458por Tyker, Albina, Ventura, Iazsmin Bauer, Lee, Cathryn T., Strykowski, Rachel, Garcia, Nicole, Guzy, Robert, Jablonski, Renea, Vij, Rekha, Strek, Mary E., Chung, Jonathan H., Adegunsoye, Ayodeji“…Primary outcomes of death or lung transplant occurred more frequently in the high-titer RF group (HR 2.8; 95% CI 1.1–6.8; P = 0.028). High-titer RF seropositivity was associated with MLN enlargement, CT honeycombing, and decreased transplant-free survival. …”
Publicado 2021
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81459por Pak, Shin Jeong, Kim, Young Il, Yoon, Yong Sik, Lee, Jong Lyul, Lee, Jung Bok, Yu, Chang Sik“…The performance of additional procedures was an independent risk factor for surgical recurrence [hazard ratio (HR): 3.28, P = 0.02]. CONCLUSION: LICR yielded better short-term outcomes and postoperative recovery than OICR, with no differences in long-term outcomes. …”
Publicado 2021
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81460por Al Sulaiman, Khalid, Alshaya, Abdulrahman, Aljuhani, Ohoud, Alsaeed, Amjad, Alshehri, Nadiyah, Vishwakarma, Ramesh, Alzahrani, Hamdan, Althewaibi, Sara, Alghamdi, Nawaf, Alhelal, Khalid, Alharbi, Aisha, Al Harbi, Shmeylan“…Late achievement of the therapeutic trough levels was associated with higher 30-day mortality (HR: 2.54; 95% CI [1.24–5.22]; p = 0.01). Additionally, patients who achieved therapeutic trough levels of vancomycin late were more likely to develop AKI (OR = 2.59; 95% CI [1.01–6.65]; p = 0.04). …”
Publicado 2021
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