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81661por Tiu, Bruce C, Zubiri, Leyre, Iheke, James, Pahalyants, Vartan, Theodosakis, Nicholas, Ugwu-Dike, Pearl, Seo, Jayhyun, Tang, Kimberly, Sise, Meghan E, Sullivan, Ryan, Naidoo, Jarushka, Mooradian, Meghan J, Semenov, Yevgeniy R, Reynolds, Kerry L“…Compared with controls, patients with CIP had more than a threefold increased risk of needing critical care (relative risk 3.59, 95% CI, 2.31 to 5.57) and an increased risk of mortality (HR 2.34, 95% CI, 1.47 to 3.71). CONCLUSIONS: In a large claims-based analysis, PD-1/PD-L1 inhibitors increase the risk of pneumonitis in patients with lung cancer by 2.49%. …”
Publicado 2022
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81662por Qiao, Man, Li, Dongsheng, He, Yuan, Zhang, Cen, Chi, Hang, Li, Xiaoqiu, Cui, QingMing, Li, ShaoYing, Jiao, Ying, Wei, Yuan“…The 1-year overall survival rate in the EGFR mutation group was significantly higher than that in the EGFR wild group (68.18% vs. 42.86%) (HR = 0.419, 95% CI = 0.178–0.989, and P < 0.001). …”
Publicado 2022
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81663por Lura, Njål, Wagner-Larsen, Kari S., Forsse, David, Trovik, Jone, Halle, Mari K., Bertelsen, Bjørn I., Salvesen, Øyvind, Woie, Kathrine, Krakstad, Camilla, Haldorsen, Ingfrid S.“…Only MAX(imaging) independently predicted survival (HR = 1.51, p = 0.03) in the model including all size variables. …”
Publicado 2022
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81664por Machini, Beatrice, Achia, Thomas N O, Kipruto, Hillary, Amboko, Beatrice, Chesang, Jacqueline“…The cumulative incidence of discharge significantly decreased (p<0.05) by 12.7% (subdistribution-HR (SDHR): 0.873; 95% CI 0.789 to 0.967) when the respiratory rate was assessed, by 14.1% (SDHR 0.859; 95% CI 0.754 to 0.978) when oxygen saturation was monitored, by 23.1% (SDHR 0.769; 95% CI 0.709 to 0.833) and 23.4% (SDHR 0.766; 95% CI 0.704 to 0.833) when haemoglobin/haematocrit and glucose/random blood sugar were performed, respectively, and by 30.4% (SDHR 0.696; 95% CI 0.626 to 0.774) when patients had at least one clinical feature of severe malaria. …”
Publicado 2022
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81665por Wennstig, A.-K., Garmo, H., Wadsten, L., Lagerqvist, B., Fredriksson, I., Holmberg, L., Blomqvist, C., Nilsson, G., Sund, M.“…Women who received left-sided RT had a significantly higher risk of a PCI in the left anterior descending artery (LAD) compared to women who received right-sided RT, hazard ratio (HR) 1.44 (95% confidence interval [CI] 1.21–1.77, p < 0.001). …”
Publicado 2022
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81666por Zhao, Naizhuo, Smargiassi, Audrey, Jean, Sonia, Gamache, Philippe, Laouan-Sidi, Elhadji-Anassour, Chen, Hong, Goldberg, Mark S., Bernatsky, Sasha“…Cox proportional hazards models with annual exposure levels were used to calculate hazard ratios (HRs) for SARDs incidence, adjusting for sex, age, urban-versus-rural residence, and socioeconomic status. RESULTS: The adjusted HR for SARDS related to one interquartile range increase in PM(2.5) (3.97 µg/m(3)) was 1.12 (95% confidence interval 1.08–1.15), but there was no clear association with ozone. …”
Publicado 2022
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81667por Jahn, Nora, Völker, Maria Theresa, Laudi, Sven, Stehr, Sebastian, Schneeberger, Stefan, Brandacher, Gerald, Sucher, Elisabeth, Rademacher, Sebastian, Seehofer, Daniel, Hau, Hans Michael, Sucher, Robert“…Multivariate analysis revealed the choice of VAs as an independent prognostic factor for graft failure three months after SPKT (HR 0.38, 95%CI: 0.17–0.84; p = 0.029). Conclusions: In our study, sevoflurane and desflurane were associated with significantly increased early graft survival as well as decreased IRI-associated post-transplant clinical outcomes when compared with the isoflurane group and should be the focus of future clinical studies evaluating the positive effects of different VA agents in patients receiving SPKT.…”
Publicado 2022
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81668por Chu, Jian H., Michos, Erin D., Ouyang, Pamela, Vaidya, Dhananjay, Blumenthal, Roger S., Budoff, Matthew J., Blaha, Michael J., Whelton, Seamus P.“…However, women with EM had a significantly higher 15-year risk with an adjusted HR of 1.96 (95% CI: 1.26–3.04). In multivariable Cox models, women with CAC ≥ 1 had progressively increased ASCVD risk that did not significantly differ by EM status. …”
Publicado 2022
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81669Patterns and outcomes of subsequent therapy after immune checkpoint inhibitor discontinuation in HCCpor Sharma, Rohini, Pillai, Anjana, Marron, Thomas Urban, Fessas, Petros, Saeed, Anwaar, Jun, Tomi, Dharmapuri, Sirish, Szafron, David, Naqash, Abdul Rafeh, Gampa, Anuhya, Wang, Yinghong, Khan, Uqba, Muzaffar, Mahvish, Lee, Chieh‐Ju, Lee, Pei‐Chang, Bulumulle, Anushi, Paul, Sonal, Bettinger, Dominic, Hildebrand, Hannah, Yehia, Mohammed, Pressiani, Tiziana, Kaseb, Ahmed, Huang, Yi‐Hsiang, Ang, Celina, Kudo, Masatoshi, Nishida, Naoshi, Personeni, Nicola, Rimassa, Lorenza, Pinato, David James“…Receipt of post‐ICI therapy was associated with longer median OS compared with those who had received BSC (12.1 vs. 3.3 months; hazard ratio [HR]: 0.4 (95% CI: 2.7–5.0). No difference in OS was noted in those patients who received TKI before ICIs compared with those who received ICIs followed by TKI. …”
Publicado 2022
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81670por Szarek, Michael, Hess, Connie, Patel, Manesh R., Jones, W. Schuyler, Berger, Jeffrey S., Baumgartner, Iris, Katona, Brian, Mahaffey, Kenneth W., Norgren, Lars, Blomster, Juuso, Rockhold, Frank W., Hsia, Judith, Fowkes, F. Gerry R., Bonaca, Marc P.“…Among 13 885 randomized patients, 7600 total cardiovascular and limb events occurred during a median 2.7 years of follow‐up, translating to 60.0 and 62.5 events per 100 patients through 3 years for the ticagrelor and clopidogrel groups, respectively (HR, 0.96; 95% CI, 0.89–1.03; P=0.27). Among 1393 patients with disease in 3 vascular territories, event accrual rates through 3 years for the ticagrelor and clopidogrel groups were 87.3 and 97.7 events per 100 patients, respectively. …”
Publicado 2022
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81671por Prosser, Hamish C., Peck, Kah Yong, Dinh, Diem, Roberts, Louise, Chandrasekhar, Jaya, Brennan, Angela, Duffy, Stephen J., Clark, David, Ajani, Andrew E., Oqueli, Ernesto, Sebastian, Martin, Reid, Christopher M., Freeman, Melanie, Sajeev, Jithin K., Teh, Andrew W.“…Kaplan–Meier analysis demonstrated ACEi/ARB use was associated with a significantly lower mortality in the entire cohort (15.0 vs. 22.7%; p < 0.001) with a mean follow-up of 5.58 years; and independently associated with 24% lower mortality by Cox proportional hazards modelling (HR 0.76, CI 0.67–0.85, p < 0.001). ACEi/ARB therapy was also associated with significantly lower mortality in patients with reduced or preserved LV function, with greater survival benefit with worse LV dysfunction. …”
Publicado 2022
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81672“…The relationships of C4 and HR for the three endpoints showed a positive linear trend. …”
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81673por Kjærgaard, Kasper Aalbæk, Harborg, Sixten, Jensen, Henrik Kjærulf, Borgquist, Signe“…Thus, the risk among mutation-carrying HeFH relatives compared with nonmutation-carrying HeFH relatives was increased (HR: 2.39; 95% CI, 1.24–4.61). CONCLUSION: In Denmark, LDLR mutation-carrying HeFH relatives did not have a different cancer risk than the general population. …”
Publicado 2022
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81674por Li, Ben, Zamzam, Abdelrahman, Syed, Muzammil H., Jahanpour, Niousha, Jain, Shubha, Abdin, Rawand, Qadura, Mohammad“…MALE and worsening PAD status were observed in 21 (10%) and 28 (14%) patients, respectively. uFABP3/uCr predicted MALE and worsening PAD status with adjusted hazard ratios (HR) of 1.28 (1.16–1.41, p = 0.001) and 1.16 (1.02–1.27, p = 0.021), respectively. …”
Publicado 2022
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81675por Pei, Gaiqin, Qin, Aiya, Dong, Lingqiu, Wang, Siqing, Liu, Xiang, Yang, Dandan, Tan, Jiaxing, Zhou, Xiaoyuan, Tang, Yi, Qin, Wei“…Multivariate Cox analysis demonstrated that a high TG/HDL-C ratio (HR 1.775, 95% CI 1.056-2.798; P=0.029) was an independent predictive marker to ESRD. …”
Publicado 2022
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81676por Lin, Qi, Bao, Jia-Hao, Xue, Fei, Qin, Jia-Jun, Chen, Zhen, Chen, Zhong-Rong, Li, Chao, Yan, Yi-Xuan, Fu, Jin, Shen, Zhao-Li, Chen, Xian-Zhen“…RESULTS: AA patients with chemotherapy were at a lower HDRD risk compared to those patients without chemotherapy (adjusted HR=0.782, 95%CI=0.736–0.83, P<0.001). For competing risk regression analysis, the cumulative incidence of HDRD in non-chemotherapy exceeded HDRD in the chemotherapy group (P<0.001) and multivariable analysis showed a lower HDRD risk in AA patients with chemotherapy (adjusted SHR=0.574, 95%CI=0.331–0.991, P=0.046). …”
Publicado 2022
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81677por Kinumaki, Keiko, Imano, Hironori, Takao, Yukiko, Okuno, Yoshinobu, Mori, Yasuko, Asada, Hideo, Yamanishi, Koichi, Iso, Hiroyasu“…RESULTS: Compared to no HZ history of each family member, a history of brother or sister was associated with a higher risk of incident HZ while histories of father and mother were not. The multivariable HR (95%CI) of incident HZ for a history of brother or sister was 1.67 (1.04–2.69). …”
Publicado 2022
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81678por Daimer, Sarah, Mihatsch, Lorenz L, Neufeld, Sharon AS, Murray, Graham K, Knolle, Franziska“…Importantly, we found that excessive media consumption (>4 hr per day) fully mediated the relationship between COVID-19 related life concerns and schizotypal traits in the January/February 2021 survey. …”
Publicado 2022
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81679por Trenaman, Shanna C., Harding, Austin, Bowles, Susan K., Kirkland, Susan A., Andrew, Melissa K.“…Cox regression demonstrated an increased risk of starting a PPI within 180 days when initiating any medication from the ACB (HR 1.38, 95%CI [1.29–1.58]). Discussion: Regression modelling suggested that anticholinergic medications increased the risk of PPI dispensation consistent with a prescribing cascade in the cohort. …”
Publicado 2022
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81680por Xiao, Lu-shan, Li, Rui-ning, Cui, Hao, Hong, Chang, Huang, Chao-yi, Li, Qi-mei, Hu, Cheng-yi, Dong, Zhong-yi, Zhu, Hong-bo, Liu, Li“…Multivariate analysis revealed that sarcopenia (hazard ratio [HR], 5.39; 95% confidence interval [CI], 1.74–16.74; p = 0.004) was a significant predictor of overall survival (OS). …”
Publicado 2022
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