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  1. 81981
    “…Median PFS was significantly longer in cohort A than in cohort B (NR [95% CI 21.4–NR] vs. 16.0 months [13.0–22.5]; HR 0.375, 95% CI 0.192–0.735; p=0.003). The PFS rates at 12 and 18 months were 84.8% (95% CI 75.0–95.9) and 71.3% (95% CI 58.7–86.7) in cohort A and 75.0% (95% CI 60.6–92.9) and 38.3% (95% CI 23.7–61.7) in cohort B, respectively. …”
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    Concurrent sintilimab with sequential chemoradiotherapy for unresectable, stage III non-small cell lung cancer: a retrospective study
  2. 81982
    “…Moreover, multivariable analysis identified ET ≥ C(D) (HR 0.61 [95% CI 0.43–0.87; p < 0.007]) to be associated with beneficial outcome after TAVI, independent from clinical risk factors and echocardiography-derived parameters. …”
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    Prognostic impact and diagnostic value of invasively derived hemodynamic measures in patients with severe aortic stenosis undergoing TAVI
  3. 81983
    “…CHIP-driver mutations were associated with a significantly higher mortality up to 4 years after TAVR in both univariate (p = 0.031) and multivariate analyses (HR 1.429, 95%CI 1.014–2.013, p = 0.041). The difference was even more pronounced (p = 0.011) in never smokers. …”
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    Long-term risk associated with clonal hematopoiesis in patients with severe aortic valve stenosis undergoing TAVR
  4. 81984
    “…And there was no significant relation between chemotherapy and CSD in the multivariate competing risks regression analysis (HR, 0.79; 95% CI, 0.48–1.31; p = 0.36). Furthermore, based on the variables from the multivariate analysis, a competing event nomogram was created to assess the 1-, 3-, and 5-year risks of CSD. …”
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    De-escalating chemotherapy for stage I–II gastric neuroendocrine carcinoma? A real-world competing risk analysis
  5. 81985
    “…After adjusting for factors associated with inferior OS in the univariate Cox model, POD24 remained associated with significantly inferior OS (HR = 2.50, 95% CI = 1.53–4.09, p = 0.0003) in multivariable analysis. …”
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    Impact of early relapse within 24 months after first-line systemic therapy (POD24) on outcomes in patients with marginal zone lymphoma: A US multisite study
  6. 81986
    “…Interestingly, Sob-AM2 treatment increased the expression of several T3-dependent genes in the brain such as Hr, Shh, Dio3, Kcnj10, Klf9, and Faah in Mct8/Dio2 KO fetuses. …”
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    Maternal Administration of the CNS-Selective Sobetirome Prodrug Sob-AM2 Exerts Thyromimetic Effects in Murine MCT8-Deficient Fetuses
  7. 81987
    “…However, AM HSD-1 reductase activity is impaired in patients with sepsis-related ARDS, compared to sepsis patients without ARDS and lobectomy patients (0.075 v 0.882 v 0.967 pM/hr/10(6) AMs, p=0.004). Across all sepsis patients (with and without ARDS), impaired AM HSD-1 reductase activity is associated with defective efferocytosis (r=0.804, p=0.008) and increased 30-day mortality. …”
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    Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS
  8. 81988
    “…This was not related to differences in endoxifen concentration (HR 1.0, 95% CI 0.96–1.04, p = 0.84) or CYP polymorphisms. …”
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    Tamoxifen pharmacokinetics and pharmacodynamics in older patients with non-metastatic breast cancer
  9. 81989
    “…Three factors including sex and bilateral symptoms (HR: 0.49[0.30–0.80], 0.33[0.15–0.72], respectively) were associated with a poor outcome in a single cohort study. …”
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    Predicting the outcome of plantar heel pain in adults: a systematic review of prognostic factors
  10. 81990
    por Zhu, Zongyi, Jiang, Huiqing
    Publicado 2023
    “…In multivariate analysis, presence of ACLF remained as an independent risk factor for 6-week mortality after adjusting for confounding factors (HR = 2.12, P = 0.03). The discrimination, calibration and overall performance of CLIF-C ACLF and CLIF-C AD were superior to the traditional prognostic scores (CTP, MELD and MELD-Na) in the prediction of 6-week mortality of patients with and without ACLF, respectively. …”
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    Risk stratification based on acute-on-chronic liver failure in cirrhotic patients hospitalized for acute variceal bleeding
  11. 81991
    por Wang, Lina, Zhang, Xiaolin, Liu, Xinmin
    Publicado 2023
    “…Meta-analysis showed that frailty was associated with an increased risk of long-term all-cause mortality (HR 1.68; 95% CI 1.37–2.05; I(2) = 0%, P < 0.001). …”
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    Prevalence and clinical impact of frailty in COPD: a systematic review and meta-analysis
  12. 81992
    “…Men had a higher risk of being diagnosed with liver cancer than women, with a hazard ratio (HR) of 3.9 (95% confidence interval 3.6–4.2) for HCC, 1.2 (1.1–1.3) for CCA, and 1.7 (1.5–2.0) for other specified/unspecified liver cancer. …”
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    Disparities in care and outcomes for primary liver cancer in England during 2008–2018: a cohort study of 8.52 million primary care population using the QResearch database
  13. 81993
    “…Only treatment modality was associated with overall survival after adjusting for covariates (HR 0.37, P<0.001, reference group: bimodality). …”
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    ‘CROSS’-ing into the ‘Real World’: a retrospective cohort study of patients receiving trimodality and bimodality therapy for esophageal cancer
  14. 81994
    “…Sedentary time was only found to be linked to all-cause dementia, and the HR for high sedentary time was 1.03 (1.01–1.06) compared with that for low sedentary time. …”
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    The independent and joint association of accelerometer-measured physical activity and sedentary time with dementia: a cohort study in the UK Biobank
  15. 81995
    “…PS‐adjusted Cox regression confirmed a significantly better survival for HM3 patients when compared with HVAD, with a HR of 1.46 (95% confidence interval 1.14–1.85, P < 0.01). …”
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    Identifying patients at risk: multi‐centre comparison of HeartMate 3 and HeartWare left ventricular assist devices
  16. 81996
    “…RESULTS: Cox regression showed that patients increasing plant protein intake were more likely to remit from diabetes than those who decreased its intake (HR = 1.71(1.05–2.77)). The remission occurred mainly at first and second year of follow-up with diminished number of patients achieving remission in the third year onwards. …”
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    Changes in quantity plant-based protein intake on type 2 diabetes remission in coronary heart disease patients: from the CORDIOPREV study
  17. 81997
    “…RESULTS: Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) at T incision and 30 min after T incision were significantly higher in group C than in group N, and also significantly higher than at baseline (P < 0.01). …”
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    The Role of Ultrasound-Guided Multipoint Fascial Plane Block in ElderlyPatients Undergoing Combined Thoracoscopic–Laparoscopic Esophagectomy: A Prospective Randomized Study
  18. 81998
    “…Median survival time, predicted mean survival time, hazard ratio (HR), and 95% confidence interval (CI) were calculated. …”
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    Survival analysis of implants after surgical treatment of peri-implantitis based on bone loss severity and surgical technique: a retrospective study
  19. 81999
    “…LCT-PV with the highest 10% PRS was independently associated with AF recurrence after AFCA (HR 2.10, 95% CI 1.21-3.63, p=0.008). CONCLUSIONS: Among the patients who underwent AFCA, PV variation, including LCT-PV, has a significant genetic background. …”
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    Left common trunkus pulmonary veins have genetic background and poor rhythm outcome after atrial fibrillation catheter ablation
  20. 82000
    “…Most admissions were in AF 78% (n=39) or AFL 18% (n=9), with two admissions frequently alternating between sinus rhythm and AF 4% (n=2). Mean HR at the time of admission and discharge was 122 ± 26 and 82 ± 27 bpm, respectively. …”
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    Telemedicine: the future of personalised atrial fibrillation care in a post pandemic world?
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