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  1. 82001
    “…QRS duration was the only characteristic associated with increased risk with a hazard ratio (HR) of 1.04 or 1.05 per ms for events and lethal events, respectively. …”
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    Ventricular conduction is a marker for arrhythmic risk in overlap sodium channel disease
  2. 82002
    “…Non-frail patient group showed the most beneficial survival with a 70% (HR 0.31; 95% CI: 0.23-0.41; p<0.001) lower all-cause mortality risk compared to Frail group 2. …”
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    The prevalence and importance of frailty in cardiac resynchronization therapy patients
  3. 82003
    “…Participants in the highest quartile in the fully adjusted model had a relatively decreased risk of developing lung cancer in comparison to those in the lowest quartile (HR(quartile 4 versus 1): 0.647; 95% CI: 0.557, 0.752; P(trend) < 0.001). …”
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    Association between dietary approaches to stop hypertension eating pattern and lung cancer risk in 98,459 participants: results from a large prospective study
  4. 82004
    “…Maintenance of ≥7% weight loss at 1 year was associated with a 68% lower risk of developing nephropathy for up to 10 years compared with maintenance of <7% weight loss (adjusted HR for group B: 0.32, 95% CI 0.11, 0.9, p=0.007). …”
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    Long-term effect of intensive lifestyle intervention on cardiometabolic risk factors and microvascular complications in patients with diabetes in real-world clinical practice: a 10-year longitudinal study
  5. 82005
    “…VAP was not an independent risk factor for ICU mortality (Hazard Ratio, HR = 0.71 95%CI 0.43–1.16, p = 0.168), but was independently associated with longer ICU stay (OR = 2.55 95%CI 2.01–3.23, p < 0.001). …”
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    Ventilator-associated pneumonia in neurocritically ill patients: insights from the ENIO international prospective observational study
  6. 82006
    “…After adjusting for 17 potential confounders, the presence of anemia significantly increased the risk of death (HR = 2.68; 95% CI: 1.59–4.52) and of risk of severe COVID-19 (OR = 2.31; 95% CI: 1.65–3.24). …”
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    Anemia as a risk factor for disease progression in patients admitted for COVID-19: data from a large, multicenter cohort study
  7. 82007
    “…Survival analysis revealed significant differences between subtypes and severe iMCD (HR = 3.747; 95% CI: 2.112–6.649, p < 0.001) had worse outcome. …”
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    A national, multicenter, retrospective study of Castleman disease in China implementing CDCN criteria
  8. 82008
    “…Microcirculatory values 24 h after admission and 30-day mortality did not differ [crude: 32 (47.1%) patients versus 25 (34.7%), relative risk (RR) 1.39 (0.91–1.97); Cox-regression: hazard ratio (HR) 1.54 (95% confidence interval (CI) 0.90–2.66, p = 0.118)]. …”
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    Direct assessment of microcirculation in shock: a randomized-controlled multicenter study
  9. 82009
    “…The median OS was 17.22 months (95% CI 12.19–21.68 months) in the experimental group and 7.69 months (95% CI 5.16–22.67 months) in the control group, showing no significant difference by the log-rank test (HR: 0.78; 95% CI 0.39–1.58; p = 0.473). The overall response rate and disease control rate were 9.3% and 46.5% in the control group and 5.3% and 47.4% in the experimental group, respectively. …”
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    Efficacy and safety of metformin plus low-dose temozolomide in patients with recurrent or refractory glioblastoma: a randomized, prospective, multicenter, double-blind, controlled, phase 2 trial (KNOG-1501 study)
  10. 82010
    “…Both multivariant Cox regression and logistic regression showed that FT4 levels lower than 1.2 μg/dl can independently predict 30-day mortality when adjusted for other potential confounders (HR = 0.34, 95% CI = 0.14–0.82; OR = 0.21, 95% CI = 0.06–0.79, respectively), but its predictive power disappeared when adjusted for T3 or total T4. …”
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    Association between serum-free thyroxine level and all-cause mortality in critically ill patients: a retrospective study from MIMIC-IV
  11. 82011
    “…Absence of DM in high-grade BC correlated with reduced RFS (HR:1.96, 95%CI:1.0–3.79, p = 0.045). CONCLUSION: Sufficient time for a TUR-BT is mandatory to assure DM in the TUR-BT specimen. …”
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    Absence of detrusor muscle in TUR-BT specimen – can we predict who is at highest risk?
  12. 82012
    “…BACKGROUND: The Choosing Wisely initiative recommended the omission of routine sentinel lymph node biopsy (SLNB) in patients ≥ 70 years of age, with clinically node-negative, early stage, hormone receptor (HR) positive and human epidermal growth factor receptor 2 (Her2) negative breast cancer in August 2016. …”
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    Use of sentinel lymph node biopsy in elderly patients with breast cancer – 10-year experience from a Swiss university hospital
  13. 82013
    “…In the current study we investigated whether COVID-19 vaccination long-lastingly affects plasma interleukin (IL)-6 concentrations, complete blood counts, ex vivo IL-6 and IL-10 secretion of PBMCs cultured under basal conditions or in the presence of concanavalin (Con) A and lipopolysaccharide (LPS), salivary cortisol and α-amylase, mean arterial pressure (MAP), heart rate (HR) as well as mental and physical health status. …”
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    COVID-19 vaccination exacerbates ex vivo IL-6 release from isolated PBMCs
  14. 82014
    “…The patients with micro lymph node metastasis had a poor prognosis (HR for OS of 2.199, 95% CI = 1.335–3.622, P = 0.002). …”
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    Clinical implications of micro lymph node metastasis for patients with gastric cancer
  15. 82015
    “…Results from subgroup analysis demonstrated that spinal anesthesia could significantly decrease the incidence of cancer recurrence in comparison with general anesthesia (RR 0.80, 95%CI 0.72–0.88, P < 0.001) and high-risk NMIBC patients who received RA tended to have less recurrence (HR 0.55, 95%CI 0.39–0.79, P = 0.001) than those receiving GA. …”
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    Effect of regional versus general anesthesia on recurrence of non-muscle invasive bladder cancer: a systematic review and meta-analysis of eight retrospective cohort studies
  16. 82016
    “…Após a análise multivariada, o sexo feminino não foi associado a ECAMs (HR = 1,14; IC95% 0,86 – 1,51; p = 0,36). CONCLUSÃO: Em uma coorte prospectiva contemporânea de pacientes com IAMCSST submetidos à ICPp, pacientes do sexo feminino apresentaram idade mais avançada e mais comorbidades no basal que os pacientes do sexo masculino, mas não houve diferenças significativas entre os sexos quanto aos desfechos adversos no hospital ou em longo prazo.…”
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    Diferenças entre os Sexos nos Desfechos de Pacientes com Infarto do Miocárdio com Supradesnivelamento do Segmento ST Submetidos à Intervenção Coronária Percutânea Primária
  17. 82017
    “…According to the results, combining EGFR-TKIs with angiogenesis inhibitors therapy prolonged PFS of advanced EGFR-mutation NSCLC patients on the whole [HR:0.65 (95%CI: 0.59~0.73, P<0.00001)]. No significant statistical difference was identified between the combination group and single drug group in OS(P=0.20) and ORR (P=0.11). …”
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    Efficacy and safety of EGFR-TKIs in combination with angiogenesis inhibitors as first-line therapy for advanced EGFR-mutant non-small-cell lung cancer: a systematic review and meta-analysis
  18. 82018
    “…The joint model demonstrated an independent association between temporal evolution of troponin and risk of cardiovascular death (HR per doubling, 1.45, 95% CI,1.33–1.75). CONCLUSIONS: Cardiac troponin I concentrations increased in those dying from cardiovascular disease compared to those surviving or dying from other causes over the preceding decades. …”
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    Trajectories of cardiac troponin in the decades before cardiovascular death: a longitudinal cohort study
  19. 82019
    “…In addition, the patients with CPFE combined with PH had a poor prognosis than patients with CPFE without PH (HR: 6.16; 95% CI: 2.53–15.03; P < 0.01). CONCLUSIONS: Our meta-analysis showed that patients with CPFE were associated with a significantly higher risk of PH compared with those with IPF or emphysema alone. …”
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    An increased risk of pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema: a meta-analysis
  20. 82020
    “…DATA EXTRACTION: The meta-analysis was conducted by pooling relative risk (RR), odds ratio (OR) or hazards ratio (HR) with 95% confidence intervals (CIs). Potential sources of heterogeneity were detected by subgroup analysis. …”
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    Associations between food groups and liver cancer: a systematic review and meta-analysis of observational studies
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