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82061por Shearn, Colin T., Anderson, Aimee L., Devereaux, Michael W., El Kasmi, Karim C., Orlicky, David J., Sokol, Ronald J.“…Animals were NPO on a 14 hr light-dark cycle and were administered PN continuously over 24 hrs. …”
Publicado 2023
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82062por Patel, Aarti A., Ferrante, Shannon Allen, Lin, Iris, Fu, Alex Z., Campbell, Alicia K., Tieng, Arlene“…After adjusting for baseline characteristics, Black patients had significantly longer time to initiation of any DMARD (HR [95% CI] 0.82 [0.71–0.94]) and biologic DMARD (0.84 [0.71–0.99]) compared with White patients. …”
Publicado 2023
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82063por McNamara, Ryan P., Maron, Jenny S., Boucau, Julie, Roy, Vicky, Webb, Nicholas E., Bertera, Harry L., Barczak, Amy K., Positives Study Staff, The, Franko, Nicholas, Logue, Jennifer K., Kemp, Megan, Li, Jonathan Z., Zhou, Ling, Hsieh, Ching-Lin, McLellan, Jason S., Siedner, Mark J., Seaman, Michael S., Lemieux, Jacob E., Chu, Helen Y., Alter, Galit“…Strong responses were observed on the fusion peptide (FP) region and the heptad repeat 1 (HR1) region adjacent to the RBD. Notably, the FP is highly conserved across SARS-related coronaviruses and even non-SARS-related betacoronavirus. …”
Publicado 2023
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82064por Ehrler, Melanie, Wettach, Corina, Beck, Ingrid, Valsangiacomo Buechel, Emanuela R., Latal, Beatrice, Landolt, Markus A.“…AIMS: Having a child with congenital heart disease (CHD) can affect parental health-related quality of life (HR-QoL). We investigated the long-term trajectories of mental HRQoL (m-HRQoL) in mothers of children with CHD and examined risk factors for persistent low m-HRQoL. …”
Publicado 2023
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82065por Huang, Rihua, Xu, Xinghao, Xu, Chaoguang, Zhang, Shaozhao, Xiong, Zhenyu, Liu, Menghui, Huang, Yiquan, Wen, Han, Guo, Yue, Liao, Xinxue, Zhuang, Xiaodong“…After fully adjusting for confounders, a per-unit increase in the TyG index was associated with a 62% higher all-cause mortality risk (HR 1.622, 95% CI 1.086–2.416, p = 0.018). The restricted cubic splines regression model revealed a linear association between the TyG index and the risk of all-cause mortality (p for nonlinearity = 0.632). …”
Publicado 2023
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82066“…Multivariate Cox regression analysis showed that CYFRA21-1>3.3 ng/mL was an independent risk factor for the development of OS in patients with NSCLC, and GNRI>97.09 was a protective factor [hazard ratio (HR)=0.52, 95% confidence interval (CI): 0.34-0.79, P<0.05]. …”
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82067“…While most noninvasive scores were developed for the diagnosis of nonalcoholic fatty liver disease (NAFLD), consequently, the objective of this study was to systematically assess the diagnostic ability of 12 noninvasive scores (METS-IR/TyG/TyG-WC/TyG-BMI/TyG-WtHR/VAI/HSI/FLI/ZJU/FSI/K-NAFLD) for MAFLD. METHODS: The study recruited eligible participants from two sources: the National Health and Nutrition Examination Survey (NHANES) 2017-2020.3 cycle and the database of the West China Hospital Health Management Center. …”
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82068por Gui, Si-Yu, Wang, Xin-Chen, Qiao, Jian-Chao, Lin, Si-Yu, Wang, Qian-Qian, Zhang, Meng-Yue, Xu, Yue-Yang, Huang, Zhi-Hao, Tao, Li-Ming, Hu, Cheng-Yang, Tao, Fang-Biao, Jiang, Zheng-Xuan, Liu, Dong-Wei“…Severity analysis showed that only mild NPR was associated with an increased all-cause mortality risk (hazard ratio (HR) = 2.01; 95% confidence interval (CI), 1.00–4.03), while increased CVD and DM-specific mortality risk were associated with all grades of retinopathy and were exponentially greater with increasing retinopathy severity, and the trend test was also significant (P for trend 0.004 and 0.04, respectively). …”
Publicado 2023
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82069por Ren, Jiayi, Zhang, Chong, Liu, Yahua, Han, Hongguang, Liang, Yong, Zhang, Qiyan, Li, Simeng, Benn, Bryan S., Nugent, Kenneth M., Qu, Hong, Liang, Guobiao, Bai, Yang“…Initial ionized calcium was found to be independently associate with both short-term [adjusted odds ratio (OR): 0.92; 95% confidence interval (CI): 0.86 to 0.99; P=0.020] and long-term mortality [adjusted hazard ratio (HR): 0.95; 95% CI: 0.92 to 0.99; P=0.010], after adjusting for potential confounders. …”
Publicado 2023
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82070“…The ESD group had a lower OS rate (HR = 2.81, 95% CI = 2.20 to 3.58, I(2) = 12.28%, P = 0.00 < 0.05). …”
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82071por Al Sulaiman, Khalid, Korayem, Ghazwa B., Aljuhani, Ohoud, Altebainawi, Ali F., Shawaqfeh, Mohammad S., Alarfaj, Sumaiah J., Alharbi, Reham A., Ageeli, Mawaddah M., Alissa, Abdulrahman, Vishwakarma, Ramesh, Ibrahim, Alnada, Alenazi, Abeer A., Alghnam, Suliman, Alshehri, Nadiyah, Alshammari, Maqbulah M., Alhubaishi, Alaa, Aldhaeefi, Mohammed, Alamri, Faisal F., Syed, Yadullah, Khan, Raymond, Alalawi, Mai, Alanazi, Khalaf A., Alresayes, Faisal S., Albarqi, Khalid J., Al Ghamdi, Ghassan“…The in-hospital mortality showed no difference between patients who received vitamin D and the control group (HR 1.22, 95% CI 0.87–1.71; p = 0.26). However, MV duration and ICU LOS were longer in the vitamin D group (beta coefficient 0.24 (95% CI 0.00–0.47), p = 0.05 and beta coefficient 0.16 (95% CI −0.01 to 0.33), p = 0.07, respectively). …”
Publicado 2023
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82072por Levink, Iris J. M., Jaarsma, Sanne C., Koopmann, Brechtje D. M., van Riet, Priscilla A., Overbeek, Kasper A., Meziani, Jihane, Sprij, Marloes L. J. A., Casadei, Riccardo, Ingaldi, Carlo, Polkowski, Marcin, Engels, Megan M. L., van der Waaij, Laurens A., Carrara, Silvia, Pando, Elizabeth, Vornhülz, Marlies, Honkoop, Pieter, Schoon, Erik J., Laukkarinen, Johanna, Bergmann, Jilling F., Rossi, Gemma, van Vilsteren, Frederike G. I., van Berkel, Anne‐Marie, Tabone, Trevor, Schwartz, Matthijs P., Tan, Adriaan C. I. T. L., van Hooft, Jeanin E., Quispel, Rutger, van Soest, Ellert, Czacko, Laszlo, Bruno, Marco J., Cahen, Djuna L.“…The baseline CA19.9 value was (as continuous or dichotomous variable at the 37 kU/L threshold) not independently associated with HGD or pancreatic cancer development, whilst a CA19.9 of ≥ 133 kU/L was (HR 3.8, 95% CI 1.1–13, p = 0.03). CONCLUSIONS: In this pancreatic cyst surveillance cohort, CA19.9 monitoring caused substantial harm by shortening surveillance intervals (and performance of unnecessary surgery). …”
Publicado 2023
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82073por Shen, Zaihong, Wang, Ying, Bao, Aihua, Yang, Jun, Sun, Xi, Cai, Yu, Wan, Liping, Huang, Chongmei, Xu, Xiaowei, Niu, Jiahua, Xia, Xinxin, Shen, Chang, Wei, Yu, Qiu, Huiying, Zhou, Kun, Zhang, Min, Tong, Yin, Song, Xianmin“…The 6-month overall survival (OS) of 88.89% in the early group (mNGS ≤ 7 days) was significantly higher than that of 65.52% (HR 0.287, 95% CI 0.101–0.819, P = 0.006) in the late group (mNGS > 7 days). …”
Publicado 2023
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82074“…Compared to the decreasing AIP trajectory group, the increasing AIP trajectory group had a higher risk of incident CVD (HR: 1.31, 95% CI: 1.02–1.69) after adjusting for confounders. …”
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82075por Zwart, Koen, van der Baan, Frederieke H., Punt, Cornelis J. A., Wensink, G. Emerens, Bolhuis, Karen, Laclé, Miangela M., van Grevenstein, Wilhelmina M. U., Hagendoorn, Jeroen, de Hingh, Ignace H., Koopman, Miriam, Vink, Geraldine, Roodhart, Jeanine“…Characteristics differed significantly between patients with dMMR and pMMR mCRC; however, multivariable analysis continued to demonstrate dMMR as independent factor for improved RFS [hazard ratio (HR): 0.57, 95% CI 0.38–0.87]. Median OS was 33.3 months for dMMR mCRC compared with 43.5 months for pMMR mCRC, mainly due to poor survival of patients with dMMR in cases of recurrence in the preimmunotherapy era. …”
Publicado 2023
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82076por Cherbi, Miloud, Bonnefoy, Eric, Lamblin, Nicolas, Gerbaud, Edouard, Bonello, Laurent, Roubille, François, Levy, Bruno, Champion, Sebastien, Lim, Pascal, Schneider, Francis, Elbaz, Meyer, Khachab, Hadi, Bourenne, Jeremy, Seronde, Marie-France, Schurtz, Guillaume, Harbaoui, Brahim, Vanzetto, Gerald, Combaret, Nicolas, Labbe, Vincent, Marchandot, Benjamin, Lattuca, Benoit, Biendel-Picquet, Caroline, Leurent, Guillaume, Puymirat, Etienne, Maury, Philippe, Delmas, Clément“…At 1 year, there was no difference in all-cause mortality (43% vs. 45.3%, adjusted HR 0.9 (95% CI 0.59–1.39), p = 0.64), need for HTx or VAD [10% vs. 10%, aOR 0.88 (0.41–1.88), p = 0.74], or rehospitalizations [49.4% vs. 44.4%, aOR 1.24 (0.78–1.98), p = 0.36]. …”
Publicado 2023
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82077por Amele, Sarah, Kibuchi, Eliud, McCabe, Ronan, Pearce, Anna, Henery, Paul, Hainey, Kirsten, Fagbamigbe, Adeniyi Francis, Kurdi, Amanj, McCowan, Colin, Simpson, Colin R, Dibben, Chris, Buchanan, Duncan, Demou, Evangelia, Almaghrabi, Fatima, Anghelescu, Gina, Taylor, Harry, Tibble, Holly, Rudan, Igor, Nazroo, James, Bécares, Laia, Daines, Luke, Irizar, Patricia, Jayacodi, Sandra, Pattaro, Serena, Sheikh, Aziz, Katikireddi, Srinivasa Vittal“…The risk of COVID-19 hospitalisation or death among ethnic minority groups was often higher for White Gypsy/Traveller (HR 2.21, 95% CI (1.61 to 3.06)) and Pakistani 2.09 (1.90 to 2.29) groups compared with the white Scottish group. …”
Publicado 2023
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82078A bioinformatics screen reveals hox and chromatin remodeling factors at the Drosophila histone locuspor Hodkinson, Lauren J., Smith, Connor, Comstra, H. Skye, Ajani, Bukola A., Albanese, Eric H., Arsalan, Kawsar, Daisson, Alvaro Perez, Forrest, Katherine B., Fox, Elijah H., Guerette, Matthew R., Khan, Samia, Koenig, Madeleine P., Lam, Shivani, Lewandowski, Ava S., Mahoney, Lauren J., Manai, Nasserallah, Miglay, JonCarlo, Miller, Blake A., Milloway, Olivia, Ngo, Nhi, Ngo, Vu D., Oey, Nicole F., Punjani, Tanya A., SiMa, HaoMin, Zeng, Hollis, Schmidt, Casey A., Rieder, Leila E.“…Additionally, we identified six other factors that target the histone gene array: JIL-1, hormone-like receptor 78 (Hr78), the long isoform of female sterile homeotic (1) (fs(1)h) as well as the general transcription factors TBP associated factor 1 (TAF-1), Transcription Factor IIB (TFIIB), and Transcription Factor IIF (TFIIF). …”
Publicado 2023
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82079por Zhou, Haonan, Wu, Mingdong, Yu, Shixiong, Xia, Han, Yu, Wu, Huang, Kai, Chen, Yikuan“…With multivariate analysis, D-dimer (HR 1.165, 95% CI 1.036–1.311, p = 0.011) was independent predictors of complete recanalization. …”
Publicado 2023
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82080por Weidner, Kathrin, Schupp, Tobias, Rusnak, Jonas, El-Battrawy, Ibrahim, Ansari, Uzair, Hoppner, Jorge, Mueller, Julian, Kittel, Maximilian, Taton, Gabriel, Reiser, Linda, Bollow, Armin, Reichelt, Thomas, Ellguth, Dominik, Engelke, Niko, Große Meininghaus, Dirk, Akin, Muharrem, Bertsch, Thomas, Akin, Ibrahim, Behnes, Michael“…Older patients were more often associated with all-cause mortality at 2.5 years (27% vs. 50%; hazard ratio, HR = 2.137; 95% confidence interval, CI 1.809–2.523, p = 0.001) and the secondary endpoints. …”
Publicado 2022
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