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82301por Kang, Ruihua, Luo, Liuhong, Chen, Huanhuan, Zhu, Qiuying, Liao, Lingjie, Xing, Hui, Zhu, Jinhui, Shen, Zhiyong, Lan, Guanghua, Tang, Zhenzhu, Shao, Yiming, Yang, Wenmin, Ruan, Yuhua“…Using Cox proportional hazard models, zidovudine-based (AZT-based) regimen versus stavudine-based (D4T-based) regimen had an adjusted HR (AHR) for death of 0.65 (95% CI 0.58 to 0.73); the AHR of tenofovir-based (TDF-based) versus D4T-based regimens was 0.81 (95% CI 0.71 to 0.92), and of lopinavir–ritonavir-based (LPV/r-based) versus D4T-based regimens, 1.19 (95% CI 1.04 to 1.37). …”
Publicado 2019
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82302“…Significant decreases in glomerular filtration rate (7.031 ± 1.6 ml/hr./kg), urine flow (0.2761 ± 0.06 ml/h/kg), total solute excretion (0.11 ± 0.03 meq/m), and mean blood pressure (83.5 ± 2.6 mm hg) were seen in rats with heart failure. …”
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82303por Jay, Melanie, Orstad, Stephanie L, Wali, Soma, Wylie-Rosett, Judith, Tseng, Chi-Hong, Sweat, Victoria, Wittleder, Sandra, Shu, Suzanne B, Goldstein, Noah J, Ladapo, Joseph A“…All participants receive a 1-year commercial weight loss programme membership, self-monitoring tools (bathroom scale, food journal and Fitbit Alta HR), health education and monthly check-in visits. …”
Publicado 2019
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82304por Mrad, Sawssan, Rejeb, Hadhemi, Ben Abdallah, Jihene, Graiet, Hajer, Ben Khelifa, Mouna, Abed, Amel, Ferchichi, Salima, Limem, Khelifa, Ben Saad, Helmi“…Blood samples of OS (homocysteine [μmol/L], thiobarbituric acid reactive substances [TBARS, μmol/L]) and AOS (catalase [U/ml], ceruloplasmin [g/L], superoxide dismutase [SOD, ng/ml], zinc [µmol/L], albumin [g/L]) biomarkers were consistently taken 4.5 to 2.5 hr before the iftar. Findings were analyzed by applying Friedman or Kruskal–Wallis ANOVA. …”
Publicado 2019
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82305por Swindell, William R., Kruse, Colin P. S., List, Edward O., Berryman, Darlene E., Kopchick, John J.“…The gene encoding copper chaperone for superoxide dismutase (CCS) was most strongly associated with survival (HR = 0.77; P = 1.84e−05) and other survival-associated genes were linked to mitochondrial respiration. …”
Publicado 2019
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82306por Chung, Fu-Tsai, Chou, Chun-Liang, Lo, Yu-Lun, Kuo, Chih-Hsi, Wang, Tsai-Yu, Wang, Chun-Hwa, Huang, Hung-Yu, Lin, Horng-Chyuan, Chang, Chih-Hao, Lee, Chung-Shu, Chen, Hao-Cheng, Lin, Shu-Min“…Patients who received chemotherapy and cryotherapy had better survival than patients who received only cryotherapy (median, 472 vs. 169 days; log-rank test, p = 0.02; HR 0.37; 95% CI 0.16–0.89). CONCLUSION: Cryotherapy could be useful management of MEM by flexible bronchoscopy. …”
Publicado 2019
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82307por Trojsi, Francesca, Siciliano, Mattia, Femiano, Cinzia, Santangelo, Gabriella, Lunetta, Christian, Calvo, Andrea, Moglia, Cristina, Marinou, Kalliopi, Ticozzi, Nicola, Ferro, Christian, Scialò, Carlo, Sorarù, Gianni, Conte, Amelia, Falzone, Yuri M., Tortelli, Rosanna, Russo, Massimo, Sansone, Valeria Ada, Chiò, Adriano, Mora, Gabriele, Silani, Vincenzo, Volanti, Paolo, Caponnetto, Claudia, Querin, Giorgia, Sabatelli, Mario, Riva, Nilo, Logroscino, Giancarlo, Messina, Sonia, Fasano, Antonio, Monsurrò, Maria Rosaria, Tedeschi, Gioacchino, Mandrioli, Jessica“…Cox proportional hazards regression multivariate analysis suggested that carrying the C9orf72 repeat expansion was an independent factor negatively impacting on survival time in men (HR 1.58, 95% CI 1.07–2.33, p = 0.021), but not in women (p > 0.05) as well as in the whole sample (p > 0.05). …”
Publicado 2019
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82308“…He was obese with BMI of 31 kg/m(2), afebrile, tachycardic HR 121/min, tachypnic RR 23/min, blood pressure was 173/91, spO2 98%, oral mucosa was dry and abdomen was mildly tender.He was found to be in DKA with pH of 6.9, anion gap 23(6-12), bicarbonate 7 mEq/L(22-28), beta-hydroxy-butyrate 100 mmol/L(0.3-0.5), sodium 137 mEq/L(136-145), potassium 6 mEq/L(3.5-5.0), chloride 107 mEq/L (98-106), BUN 17 mmol/L(8-20), creatinine 1.79 mg/dL(0.7-1.3), lipase 153 U/L(<160). …”
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82309por Bansal, Rashika, Welch, James, Mandl, Adel, Cochran, Craig, Merkel, Roxanne, Tepede, Aisha, Weinstein, Lee, Simonds, William, Del Rivero, Jaydira, Kumar, Sheila, Nilubol, Naris, Patel, Dhaval, Agarwal, Sunita, Millo, Corina, Wank, Stephen, Blau, Jenny“…EGD within 3 months prior to diagnosis demonstrated near complete suppression of acid (on omeprazole 120mg BID) confirmed with an acid output of 0 mEq/hr and no visible masses within the enlarged gastric folds. …”
Publicado 2019
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82310por Kumar, Monisha Priyadarshini, Detoya, Karla Cristina, Polanco Santos, Carmen, Kennedy, Laurence“…Her 24-hour urinary metanephrine levels were normal but with elevated normetanephrine 24,364 (88-444) ug/24hr, confirming a pheochromocytoma. The normal metanephrine level in the setting of profoundly elevated normetanephrine raised concern for Von Hippel Lindau (VHL). …”
Publicado 2019
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82311“…Upon re-testing in January 2018, persistent hypercortisolemia was confirmed with 24-hr UFCs x 2 and late-night salivary cortisols x 2 that were > 2 ULN, and nonsuppressed AM cortisol after a 1 mg overnight dexamethasone suppression test. …”
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82312“…Further pertinent laboratory work-up results included but not all: cortisol 15 mcg/dL, ACTH 35.7pg/mL(7.2-63.3 pg/mL), 24 hour urine free cortisol 17mcg (ref. range <= 176 mcg/24hr), dopamine 133pg/mL (0-20pg/mL), norepinephrine 725 pg/mL (80-520 pg/mL), epinephrine 48 pg/mL (10-200 pg/mL), normetanephrine 0.82 nmol/L (0.00-0.89 nmol/L). …”
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82313“…METHOD: This was a Phase 2, randomized, placebo-controlled, double-blind trial with open-label follow-up designed to assess the efficacy of CSIG to prevent hypoglycemia and lower intravenous glucose infusion rates (GIR), in subjects < 1 year of age with CHI. CSIG (5-20 μg/kg/hr) or matching placebo was delivered through a patch pump (Omnipod®; Insulet) as a continuous subcutaneous infusion, after the minimum GIR necessary to maintain euglycemia was established. …”
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82314“…On the day of each challenge, mice were fasted for 5 hr and then received an i.p. injection of either saline or insulin (0.75mU/kg). …”
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82315“…Confirmatory tests after cessation of the OCP for 6 weeks revealed normal 24-hr urinary cortisol levels (231 and 255 nmol/day, RI: 59-413 nmol/day) and a normal 1 mg dexamethasone suppression test (44 nmol/L after administration of 1 mg dexamethasone overnight, RI <50nmol/L). …”
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82316por Khan, Inamullah, Banerjee, Moulinath, Basu, Ambar, Bharaj, Harnovdeep, Krishnan, Simmi“…Gluconate in 1000mls of Normal saline at 50-100 ml/hr), Calcium carbonate tablets and Cholecalciferol 20,000 units daily(for 10 days). …”
Publicado 2019
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82317“…Labs showed corrected total calcium 8.5 (8.6-10.3 mg/dL), Ionized calcium 1.25 (1.20-1.40 mmol/L), PTH 30 (12-88 pg/mL), 24 hr urine calcium 206 (100-300 mg/24hrs), 25 hydroxy vitamin D 32.37 (30-100 ng/mL), 1,25 dihydroxy vitamin D 60.4 (19.3-79.3 pg/mL), Phosphorus 3.7 (2.4-4.7 mg/dL) and Magnesium 2.2 (1.8-2.5 mg/dL). …”
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82318“…Physical exam was notable for slight tachycardia with HR 105, no thyromegaly or nodules, and otherwise the patient was euthyroid appearing. …”
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82319por Seely, Ellen, Stuart, Jennifer, Skurnik, Geraldine, Roche, Andrea, Tsigas, Eleni, Fitzmaurice, Garrett, Wilkins-Haug, Louise, Levkoff, Sue, Rich-Edwards, Janet“…Preeclampsia history was validated by medical record review for new-onset hypertension (systolic blood pressure ≥140 and/or diastolic blood pressure ≥90 mm Hg) with proteinuria (≥ 300 mg/24hr, or urine protein/urine creatinine ratio ≥ 0.3 or urine dipstick ≥ 1+) after 20 weeks gestation. …”
Publicado 2019
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82320“…In contrast, LSD1(+/-) had significantly higher 24-hr urine potassium than the LSD1(+/+) mice (0.29 ± 0.1 mmol vs 0.15 ± 0.02 mmol, P= 0.05), yet similar ALDO responses to eplerenone, suggesting increased MR activity. …”
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