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82401por Ramezani-Pour, Narjes, Esfahani, Sayyed Hamid Zarkesh, Pradhananga, Sarbendra, Newell-Price, John D C, Ross, Richard John M, Wilkinson, Ian R“…PTH at 20 nmol/kg given as a single sc dose abrogated the Cinacalcet-HCl induced fall in iCa for up to 2 hrs (AUC±SD (mmol/L).hr, 0.076 ±0.047 versus 0.168±0.0874, t-test P=0.0289). …”
Publicado 2020
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82402por Warde, Kate, Shoenmakers, Erik, Leonard, Maeve, Maunsells, Rebecca, Hantel, Constanze, Gurnell, Mark, Dennedy, Michael Conall“…Cholesterol-methyl-β-cyclodextrin treatment was carried out 1hr prior to mitotane. H295R cells were transfected with a LXR⍺ dominant negative construct using lipofectamine. …”
Publicado 2020
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82403“…In conclusion, the abnormalities of the circadian profile of glucocorticoid levels in AI are associated with an abnormal 24-hr profile of melatonin release, a marker of central circadian function, suggesting that the disruption of the glucocorticoid rhythm may affect central circadian function. …”
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82404“…The patient denied use of alcohol, tobacco, illicit and IV drug use. T: 37.2 °C, HR: 124, RR: 25, BP: 105/74, SpO2: 100%. Weight 45kg. …”
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82405por Sittol, Rani, Allen, Juliann, Lofters, Jason, Ran-Castillo, Dan, Williams, Karlene“…On examination he was anxious with a fine hand tremor, BP 158/80mmHg, and HR 106bpm. He had grade 2/5 power to lower limb proximal muscles and brisk reflexes. …”
Publicado 2020
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82406SAT-354 Isolated Hypoparathyroidism: A Rare Initial Manifestation of Hereditary Hemochromatosis (HH)“…His ionized calcium was also low. Patient’s 24 hr urinary Ca was 122mg/24hrs. In this case, he did initially have hypomagnesemia and vitamin d deficiency, which could potentially explain low calcium. …”
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82407“…Laboratory evaluation was notable for TSH <0.01 uIU/mL (0.39 - 4.0.8), free T4 5.19 ng/dL (0.58 - 1.64), free T3 10 pg/ml (2.53-3.87), ESR 95 mm/hr (0-20) and CRP 9.339 mg/dl (0.0-0.9) consistent with thyrotoxicosis. …”
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82408por Kaluarachchi, Vidumini, Arshad, Muhammad Fahad, Balasubramanian, Sabapathy, Lim, Chern Beverly Brenda, Bull, Matthew, Ross, Richard John M“…At the time of referral with abdominal pain, he was on hydrocortisone 10 mg mane, 10 mg midday and 5mg at 1700h and his biochemistry showed: ACTH 486ng/l (NR 7.2–63.3), 17-OHP 101.1nmol/l (0–6.0nmol/l), renin 5.5 nmol/l/hr (NR 0.2–3.3) and androstenedione 26.6 nmol/l (NR 0–7.8). …”
Publicado 2020
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82409SAT-LB91 Asparaginase Induced Severe Hypertriglyceridemia Requiring Multiple Plasmapheresis Sessions“…He was treated in the ICU with insulin drip at 0.05 - 0.1 unit/kg/hr with repeat TG level 6,490 mg/dL after 48 hours. …”
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82410“…She was kept on propranolol 80 mg q/4h, intravenous esmolol 50 mcg/kg/min, diltiazem drip 5 mg/hr, and was started on Digoxin 0.25 mg q/4h. TSI and TPO were undetectable, and thyroid ultrasound revealed a right nodule measuring 5 x 2.2 x 3.7cm. …”
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82411“…Physical exam: BP 182/119, HR 120, mild pulmonary crackles. Labs: proBNP 3533 (1-150 pg/ml), HbA1c 13.1%. …”
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82412por Tan, Ying Tse Sarah, Zhang, Meifen, Gani, Linsey, Khoo, Joan, Tan, Colin, Ng, Keng Sin, Puar, Troy H“…Aldosterone renin ratio has normalized: aldosterone <4ng/dL, plasma renin activity 0.6ng/ml/hr. Clinical Lessons While ACTH stimulation helps to improve success rates of cannulation by increasing cortisol gradients, most studies show that it lowers LR. …”
Publicado 2020
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82413por Mitchell, Kyle G, Diao, Lixia, Karpinets, Tatiana, Negrao, Marcelo V, Tran, Hai T, Parra, Edwin R, Corsini, Erin M, Reuben, Alexandre, Federico, Lorenzo, Bernatchez, Chantale, Dejima, Hitoshi, Francisco-Cruz, Alejandro, Wang, Jing, Antonoff, Mara B, Vaporciyan, Ara A, Swisher, Stephen G, Cascone, Tina, Wistuba, Ignacio I, Heymach, John V, Gibbons, Don L, Zhang, Jianjun, Haymaker, Cara L, Sepesi, Boris“…In 1524 patients, elevated preoperative circulating neutrophil count was independently associated with worse OS (main effect HR 1.82, 95% CI 1.24 to 2.68, p=0.002). CONCLUSIONS: Our findings demonstrate that neutrophil expansion reflects protumorigenic and immunosuppressive processes that manifest as worse OS in patients undergoing NSCLC resection. …”
Publicado 2020
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82414por Saharman, Yulia Rosa, Karuniawati, Anis, Sedono, Rudyanto, Aditianingsih, Dita, Goessens, Wil H. F., Klaassen, Corné H. W., Verbrugh, Henri A., Severin, Juliëtte A.“…ICU survival was lower among patients with CNKP compared to patients with carbapenem-susceptible K. pneumoniae (aHR 2.57, p = 0.005). Ninety-six of the 100 (96%) CNKP isolates carried a carbapenemase gene, predominantly bla(NDM). …”
Publicado 2020
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82415por Li, Pengyi, Gu, Lianbing, Bian, Qingming, Tan, Jing, Jiao, Dian, Wu, Fei, Xu, Zeping, Wang, Lijun“…No significant differences were found in SPO(2), ETCO(2), PaCO(2), Paw, HR and MAP among the three groups. The complications in Group C were significantly higher than another two groups. …”
Publicado 2020
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82416por Zhou, Juan, Zhou, Fei, Chu, Xiangling, Zhao, Jing, Wu, Yan, Zhao, Wencheng, Xu, Chuan, Su, Chunxia“…Surprisingly, in the subgroup of patients with liver metastases (LMs), there were dramatically significant differences in ORR (71.4% vs. 9.1%, P=0.013), DCR (85.7% vs. 18.2%, P=0.013), and median PFS [5.1 vs. 2.1 months, P=0.014, hazard ratio (HR): 0.244] between patients with (n=7) and without (n=11) NAFLD. …”
Publicado 2020
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82417por Pudkasam, Supa, Pitcher, Meron, Fisher, Melanie, O’Connor, Anne, Chinlumprasert, Nanthaphan, Stojanovska, Lily, Polman, Remco, Apostolopoulos, Vasso“…All participants will be given a wearable device (Fitbit Alta HR) and undertake self-directed physical activity for 24 weeks and will receive MI for 12 weeks (IIG; during week 0 to week 12 and DIG; during week 13 to week 24). …”
Publicado 2020
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82418por Dangrungroj, Ekkachai, Vijarnsorn, Chodchanok, Chanthong, Prakul, Chungsomprasong, Paweena, Kanjanauthai, Supaluck, Durongpisitkul, Kritvikrom, Soongswang, Jarupim, Tantiwongkosri, Kriangkrai, Subtaweesin, Thaworn, Sriyoschati, Somchai“…Significant mortality risk was weight at time of operation <4 kg (HR 3.05, 95% CI [1.05–8.74], p-value 0.041). Of the 31 operation survivors, 17 required re-intervention within 0.4–11.4 years. …”
Publicado 2020
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82419“…In particular, among multiple infections, HPV16 infection with 2 HR genotypes is associated significantly with CIN2 / CIN3 (21/30) and has 4 times greater risk of developing a high-grade lesion. …”
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82420“…The main predictor for the SAM’s post-discharge mortality was illiteracy of mothers; the adjusted HR (95%CI) was 7.10 (1.58–31.93; p = 0.01). CONCLUSIONS: Age, WAZ, edema and complications at admission were predictors for both in-hospital and total SAM mortality, while mother’s education contributed to the early post-discharge mortality. …”
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