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82521por Rastad, Hadith, Ejtahed, Hanieh-Sadat, Shafiee, Gita, Safari, Anis, Shahrestanaki, Ehsan, Khodaparast, Zeinab, Hassani, Neda Shafiabadi, Rezaei, Mohammad, Nazari, Morteza, Zakani, Akram, Niksima, Mohammad Mahdi, Azimzadeh, Mehdi, Karimi, Fatemeh, Tajbakhsh, Ramin, Qorbani, Mostafa“…After adjusting for confounding factors, age, sex, and comorbidities, ESRD patients were more likely to experience in-hospital mortality compared to non-ESRD patients (Adjusted HR (95% CI): 2.59 (1.55–4.32)). The Log-rank test revealed that there was a significant difference between the ESRD and non-ESRD groups in terms of the survival distribution (χ2 (1) = 21.18, P-value < 0.001). …”
Publicado 2021
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82522por Pieralli, Filippo, Vannucchi, Vieri, Nozzoli, Carlo, Augello, Giuseppe, Dentali, Francesco, De Marzi, Giulia, Uomo, Generoso, Risaliti, Filippo, Morbidoni, Laura, Mazzone, Antonino, Santini, Claudio, Tirotta, Daniela, Corradi, Francesco, Gerloni, Riccardo, Gnerre, Paola, Gussoni, Gualberto, Valerio, Antonella, Campanini, Mauro, Manfellotto, Dario, Fontanella, Andrea“…The occurrence of CV events during hospitalisation significantly increased the risk of 30-day mortality (HR 1.69, 95% CI 1.14–2.51; p = 0.009). CONCLUSION: Cardiovascular events are frequent in CAP, and their occurrence adversely affects outcome. …”
Publicado 2021
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82523por Wenter, Vera, Albert, Nathalie L., Unterrainer, Marcus, Ahmaddy, Freba, Ilhan, Harun, Jellinek, Annamirl, Knösel, Thomas, Bartenstein, Peter, Spitzweg, Christine, Lehner, Sebastian, Todica, Andrei“…Multivariate analysis revealed OFTC (HR 0.502; 95% CI 0.309–0.816) as the only independent prognostic factor for disease-free survival. …”
Publicado 2020
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82524por Fouad, Mariam A., Sayed-Ahmed, Mohamed M., Huwait, Etimad A., Hafez, Hafez F., Osman, Abdel-Moneim M.“…BACKGROUND: Hormonal receptor positive (HR+) breast cancer is the most commonly diagnosed molecular subtype of breast cancer; which showed good response to doxorubicin (DOX)-based chemotherapy. …”
Publicado 2021
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82525“…The risk model is closely related to the OS of LC patients. The hazard ratio (HR) is 2.184 [95% CI (confidence interval) 1.523–3.132] and log-rank P-value < 0.0001. …”
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82526por Zhang, Xinyuan, Liu, Yan, Li, Shanshan, Lichtenstein, Alice H., Chen, Shuohua, Na, Muzi, Veldheer, Susan, Xing, Aijun, Wang, Yanxiu, Wu, Shouling, Gao, Xiang“…Compared to consuming 1–25 g/wk., the adjusted HR for composite outcomes was 1.38 (95% confidence interval (CI):1.29–1.49) for non-drinker, 1.15 (95% CI: 1.04–1.27) for 26–150 g/wk., 1.22 (95% CI: 1.10–1.34) for 151–350 g/wk., 1.33 (95% CI: 1.21–1.46) for 351–750 g/wk., and 1.57 (95% CI: 1.30–1.90) for > 750 g/wk., after adjusting for age, sex, lifestyle, social economic status, and medication use. …”
Publicado 2021
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82527por Baluku, Joseph Baruch, Nakazibwe, Bridget, Naloka, Joshua, Nabwana, Martin, Mwanja, Sarah, Mulwana, Rose, Sempiira, Mike, Nassozi, Sylvia, Babirye, Febronius, Namugenyi, Carol, Ntambi, Samuel, Namiiro, Sharon, Bongomin, Felix, Katuramu, Richard, Andia-Biraro, Irene, Worodria, William“…Mild (OR: 0.57, 95% CI 0.39–0.84, p = 0.004), moderate (OR: 0.18, 95% CI 0.12–0.26, p < 0.001) and severe anaemia (OR: 0.09, 95% CI 0.05–0.17, p < 0.001) and previous exposure to SLDs (OR: 0.19, 95% CI 0.08–0.48, p < 0.001) predicted lower odds of treatment success while the number of poor prognostic indicators (HR: 1.62, 95% CI 1.30–2.01, p < 0.001), for every additional poor prognostic indicator) predicted mortality. …”
Publicado 2021
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82528por Ma, Tian-Tian, Wong, Ian C. K., Whittlesea, Cate, Man, Kenneth K. C., Lau, Wallis, Wang, Zixuan, Brauer, Ruth, MacDonald, Thomas M., Mackenzie, Isla S., Wei, Li“…Patients with any four classes of antiplatelet agents (APAs), lipid-regulating medications (LRMs), angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs), beta-blockers, diuretics and calcium channel blockers (CCBs) had the lowest risk of mortality (HR 0.51, 95% CI 0.46–0.57) versus any one class. …”
Publicado 2021
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82529“…Kaplan-Meier analysis indicated that high expression level of COL4A3 was positively associated with a favorable prognosis of head and neck squamous cell carcinoma (HR, 0.69; 95% CI, 0.49- 0.97; P=0.031). To confirm the role of COL4A3, the expression level of COL4A3 was knocked down using siRNA in the 5-8F cell line and the results showed that the invasion and migration was significantly increased when the expression of COL4A3 was inhibited (P<0.0001). …”
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82530por Xu, Guijun, Wu, Haixiao, Xu, Yao, Zhang, Yanting, Lin, Feng, Baklaushev, Vladimir P, Chekhonin, Vladimir P, Peltzer, Karl, Wang, Xin, Mao, Min, Wang, Guowen, Cui, Ping, Zhang, Chao“…Compared with chordoma, the hazard ratio (HR) and 95% CI for patients with chondrosarcoma, Ewing sarcoma, and osteosarcoma were 1.30 (95% CI: 1.04–1.62; P = 0.023), 1.69 (95% CI: 1.33–2.14; P < 0.001), and 2.00 (95% CI: 1.61–2.48; P <0.001), respectively. …”
Publicado 2020
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82531por He, Li-na, Zhang, Xuanye, Li, Haifeng, Chen, Tao, Chen, Chen, Zhou, Yixin, Lin, Zuan, Du, Wei, Fang, Wenfeng, Yang, Yunpeng, Huang, Yan, Zhao, Hongyun, Hong, Shaodong, Zhang, Li“…Multivariate Cox regression analysis revealed that higher TGR(0) independently predicted inferior PFS (hazard ratio [HR] 1.97; 95% CI, 1.08-3.60; P = 0.026). Higher TGR(0) was also significantly associated with less durable clinical benefit rate (34.8% vs. 8.8%, P = 0.007). …”
Publicado 2021
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82532por Na, Jingtao, Jin, Haifeng, Wang, Xin, Huang, Kan, Sun, Shuang, Li, Qiang, Zhang, Wenting“…Numerous parameters including left ventricular posterior wall dimension (LVPWD), interventricular septal dimension (IVSD), left ventricular end diastolic diameter (LVEDD), left ventricular end systolic diameter (LVESD), left ventricular ejection fraction (LVEF), left ventricular fractional shortening (LVFS), left ventricular systolic pressure (LVSP), left ventricular end diastolic pressure (LEVDP), heart rate (HR), left ventricular pressure rise rate (+ dp/dt) and left ventricular pressure drop rate (-dp/dt) were measured in the mice. …”
Publicado 2021
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82533“…BRAF inhibitor was the only systemic therapy to significantly impact OS on univariate analysis (HR 0.24, 95% CI 0.07–0.79, p = 0.019), and this effect extended to multivariable analysis as well. …”
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82534por Jestin, Matthieu, Azoulay, Elie, Pène, Frédéric, Bruneel, Fabrice, Mayaux, Julien, Murgier, Martin, Darmon, Michael, Valade, Sandrine“…IMV was strongly associated with ICU mortality (p < 0.001) Three variables were associated with day 90 mortality in a Cox model including allogeneic SCT (HR 4.84 [95% CI 1.64–14.32]), SOFA score (1.19 [1.02–1.39]) and dual therapy (3.02 [1.18–7.72]). …”
Publicado 2021
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82535por Raiko, Juho R. H., Saari, Teemu, Orava, Janne, Savisto, Nina, Parkkola, Riitta, Haaparanta‐Solin, Merja, Nuutila, Pirjo, Virtanen, Kirsi A.“…There was no significant change in HR, QRS duration, QTc, JTc, and T axis during cold exposure. …”
Publicado 2021
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82536por Leary, Alexandra, Genestie, Catherine, Blanc-Durand, Félix, Gouy, Sébastien, Dunant, Ariane, Maulard, Amandine, Drusch, Françoise, Cheaib, Bianca, Michels, Judith, Bentivegna, Enrica, LeFormal, Audrey, Mesnage, Soizick, Morice, Philippe, Pautier, Patricia, Khairallah, Aya S.“…Using median value as a cut-off, high stromal CD8+/FOXP3+ ratio (HR = 0.59; p = 0.017) and high stromal CD3+/FOXP3+ ratio post NACT were associated with prolonged PFS (p = 0.0226). …”
Publicado 2020
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82537por Yazaki, Kyoichiro, Suzuki, Atsushi, Shiga, Tsuyoshi, Minami, Yuichiro, Arai, Kotaro, Ashihara, Kyomi, Shoda, Morio, Hagiwara, Nobuhisa“…The combination of nonsustained ventricular tachycardia (NSVT) and IVPG ≥ 30 mmHg was found to significantly increase the risk of the main outcome (HR 6.31, 95% CI 1.36–29.25, P = 0.02). Five patients experienced ICD implant-related complications. …”
Publicado 2021
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82538“…Cox regression models were used to estimate the hazard ratio (HR) of dementia. RESULTS: During the average 5-year follow-up period, the incidence rate of dementia in the SSHL cohort was 6.5 per 1000 person-years compared with 5.09 per 10,000 person-years in the comparison group. …”
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82539por Wang, Qinchuan, Ye, Yuanqing, Yu, Hao, Lin, Shu-Hong, Tu, Huakang, Liang, Dong, Chang, David W., Huang, Maosheng, Wu, Xifeng“…The CD80 mRNA expression was associated with BCR (HR, 1.85, 95% CI 1.06–3.22, P = 0.03) in meta-analysis of validation cohorts. …”
Publicado 2020
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82540por Beaubien-Souligny, William, Yang, Alan, Lebovic, Gerald, Wald, Ron, Bagshaw, Sean M.“…Pre-existing frailty was associated with greater hazard of 90-day mortality (59% (n = 83) for frail vs. 31% (n = 100) for non-frail; adjusted hazards ratio [HR] 1.49; 95% CI 1.11–2.01, p = 0.008). At 6 months, 68 patients (28% of survivors) were frail. …”
Publicado 2021
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