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82621por An, Chao, Li, Wang-Zhong, Huang, Zhi-Mei, Yu, Xiao-Ling, Han, Yu-Zhi, Liu, Fang-Yi, Wu, Song-Song, Yu, Jie, Liang, Ping, Huang, Jinhua“…The treatment modality (RFA vs. MWA: HR 7.861, 95% CI 1.642–37.635, p = 0.010) was an independent prognostic factor for LTP. …”
Publicado 2021
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82622por Hall, Rasheeda K., Morton, Sarah, Wilson, Jonathan, Ephraim, Patti L., Boulware, L. Ebony, St. Peter, Wendy L., Colón-Emeric, Cathleen, Pendergast, Jane, Scialla, Julia J.“…Continuers experienced fewer all-cause hospitalizations and deaths, but neither were statistically significant after adjustment (Hospitalization: RR 0.93, 95% CI 0.86, 1.00; Death: HR 0.89, 95% CI: 0.78–1.02). CONCLUSIONS: Nearly one in five older adults had an antihypertensive PIM at dialysis initiation. …”
Publicado 2021
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82623por Ahn, Hyo-Jeong, Lee, So-Ryoung, Choi, Eue-Keun, Han, Kyung-Do, Jung, Jin-Hyung, Lim, Jae-Hyun, Yun, Jun-Pil, Kwon, Soonil, Oh, Seil, Lip, Gregory Y. H.“…Also, performing exercise any time before or after AF diagnosis was associated with a lower risk of mortality compared to persistent non-exercising: the HR (95% CI) was 0.82 (0.73–0.91) for new exercisers, 0.83 (0.74–0.93) for exercise dropouts, and 0.61 (0.55–0.67) for exercise maintainers (p < 0.001). …”
Publicado 2021
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82624por Häckel, Sonja, Renggli, Angela A., Albers, Christoph E., Benneker, Lorin M., Deml, Moritz C., Bigdon, Sebastian F., Ahmad, Sufian S., Hoppe, Sven“…Pain (VAS), followed by HrQoL (EQ-5D) and disability and function (RMDQ), opioid use, and radiological outcome (kyphotic angle, VBH, and new VCFs) were the most commonly used outcome parameters. …”
Publicado 2021
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82625por Almulhem, Munerah, Chandan, Joht Singh, Gokhale, Krishna, Adderley, Nicola J., Thayakaran, Rasiah, Khunti, Kamlesh, Tahrani, Abd A., Hanif, Wasim, Nirantharakumar, Krishnarajah“…SA were at an increased risk of developing: T2DM (adjusted hazard ratio (aHR) 3.1; 95% CI 2.97–3.23); HTN (1.34; 95% CI: 1.29–1.39); ischaemic heart disease (IHD) (1.81; 95% CI: 1.68–1.93) and heart failure (HF) (1.11; 95% CI: 1.003–1.24). …”
Publicado 2021
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82626por Bonthuis, Marjolein, Vidal, Enrico, Bjerre, Anna, Aydoğ, Özlem, Baiko, Sergey, Garneata, Liliana, Guzzo, Isabella, Heaf, James G., Jahnukainen, Timo, Lilien, Marc, Mallett, Tamara, Mirescu, Gabriel, Mochanova, Elena A., Nüsken, Eva, Rascher, Katherine, Roussinov, Dimitar, Szczepanska, Maria, Tsimaratos, Michel, Varvara, Askiti, Verrina, Enrico, Veselinović, Bojana, Jager, Kitty J., Harambat, Jérôme“…Five-year unadjusted patient survival on KRT was around 94% and similar for those initiating KRT 2007–2009 or 2010–2012 (adjusted HR: 0.98, 95% CI:0.71–1.35). CONCLUSIONS: We found a stable incidence and increasing prevalence of European children on KRT 2007–2016. …”
Publicado 2021
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82627por da Silva Machado, Daniel Gomes, Bikson, Marom, Datta, Abhishek, Caparelli-Dáquer, Egas, Unal, Gozde, Baptista, Abrahão F., Cyrino, Edilson Serpeloni, Li, Li Min, Morya, Edgard, Moreira, Alexandre, Okano, Alexandre Hideki“…Next, they randomly received HD-tDCS (2.4 mA), conventional (2.0 mA), or active sham tDCS (2.0 mA) over the motor cortex for 20-min before performing the TTE test. TTE, heart rate (HR), associative thoughts, peripheral (lower limbs), and whole-body ratings of perceived exertion (RPE) were recorded every minute. …”
Publicado 2021
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82628“…Vitals showed BP 108/57 mm of Hg, HR 162 beats/min, RR of 23/min. CT head without contrast showed 8 mm focal hyperdensity along the left tentorium projecting at the left occipital lobe. …”
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82629por Schettini, Francesco, Corona, Silvia Paola, Giudici, Fabiola, Strina, Carla, Sirico, Marianna, Bernocchi, Ottavia, Milani, Manuela, Ziglioli, Nicoletta, Aguggini, Sergio, Azzini, Carlo, Barbieri, Giuseppina, Cervoni, Valeria, Cappelletti, Maria Rosa, Molteni, Alfredo, Lazzari, Maria Chiara, Ferrero, Giuseppina, Ungari, Marco, Marasco, Elena, Bruson, Alice, Xumerle, Luciano, Zago, Elisa, Cerra, Davide, Loddo, Marco, Williams, Gareth H., Paris, Ida, Scambia, Giovanni, Generali, Daniele“…RESULTS: 27 patients with gBRCA-wt TNBC and 8 with gBRCA-mut BC (6 TNBC, 2 HR+/HER2-negative) were enrolled. Three (11.1%) patients showed mutations in non-BRCA1/2 DDR genes and 4 (14.8%) in other genes. 3w olaparib induced 16/35 and 15/27 partial clinical and radiometabolic responses, including in 40.7% and 50.0% gBRCA-wt patients. gBRCA-mut tumors presented numerically higher tumor-infiltrating lymphocytes (TILs) levels and PD-L1 positive tumors. …”
Publicado 2021
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82630por Duan, Ruonan, Qiao, Tian, Chen, Yue, Chen, Mengxue, Xue, Hongmei, Zhou, Xue, Yang, Mingzhe, Liu, Yan, Zhao, Li, Libuda, Lars, Cheng, Guo“…Pubertal markers consistently indicate that girls and boys with higher diet quality were more likely to enter their puberty later than their counterparts with lower CCDI scores (higher vs. lower CCDI tertiles: adjusted HR for age at B2: 0.85 (95% CI, 0.81–0.94), p for trend = 0.02; G2: 0.86 (95% CI,0.80–0.96), p for trend = 0.02; M: 0.86 (95% CI,0.80–0.95), p for trend = 0.02; VB: 0.86 (95% CI,0.79–0.98), p for trend = 0.03), after adjustment for paternal education level, baseline energy intake, and pre-pubertal body fat. …”
Publicado 2020
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82631por van den Berg, J. P., Absalom, A. R., Venema, A. M., Kalmar, A. F., Van Amsterdam, K., Hannivoort, L. N., Proost, J. H., Meier, S., Scheeren, T. W. L., Struys, M. M. R. F., Vereecke, H. E. M.“…The haemodynamic and arousal responses evoked by laryngoscopy were not significantly different between groups, but Ce(PROP) = 3.6 μg⋅ml(−1) and Ce(REMI) = 4 ng⋅ml(−1) evoked the lowest median value for ∆HR and ∆SAP after laryngoscopy. This study provides clinical insight on the haemodynamic and hypnotic consequences, when a model based predicted P(TOL) is used as a target for combined effect-site controlled target- controlled infusion of propofol and remifentanil. …”
Publicado 2020
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82632“…The gene signature was verified as an independent predictor for the OS of OSCC patients (HR > 1, p < 0.001). The receiver operating characteristic curve displayed the favour predictive performance of the risk model. …”
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82633por Huang, Yuhong, Chen, Wenben, Zhang, Xiaoling, He, Shaofu, Shao, Nan, Shi, Huijuan, Lin, Zhenzhe, Wu, Xueting, Li, Tongkeng, Lin, Haotian, Lin, Ying“…The model further achieved good AUC on the testing dataset with 30-round 5-fold cross-validation in three molecular subtypes of breast cancer as following: (1) HR+/HER2–: 0.901 (accuracy = 0.816), (2) HER2+: 0.940 (accuracy = 0.865), and (3) TN: 0.837 (accuracy = 0.811). …”
Publicado 2021
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82634“…Mortality was significantly higher among clinically diagnosed patients: 639 (9.9%) deaths compared to 285 (4.5%) amongst the bacteriologically diagnosed patients; aHR 5.16 (95%CI 2.17 − 12.3) P < 0.001. Our study suggests survival during empirical TB treatment is significantly lower compared to patients with laboratory evidence, irrespective of HIV status and age. …”
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82635por Lv, Liangjing, Zhou, Yangmei, Chen, Xiangjun, Gong, Lilin, Wu, Jinshan, Luo, Wenjin, Shen, Yan, Han, Shichao, Hu, Jinbo, Wang, Yue, Li, Qifu, Wang, Zhihong“…After confounder adjustment, patients in the high tertile of the TyG Index at baseline had a greater risk to developing DKD than those in the low tertile (HR = 1.727, 95% CI = 1.042–2.863, p = 0.034). The area under the ROC curve was 0.69 (0.63–0.76). …”
Publicado 2021
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82636por Oliveira, Rodolfo de Carvalho, Camargo, Lucila Basto, Novaes, Tatiane Fernandes, Pontes, Laura Regina Antunes, Olegário, Isabel Cristina, Gimenez, Thais, Pássaro, Ana Laura, Tedesco, Tamara Kerber, Braga, Mariana Minatel, Mendes, Fausto Medeiros, Raggio, Daniela Prócida“…Occlusoproximal restorations had lower survival rate when compared to occlusal ones (HR = 3.83; p < 0.001). CONCLUSIONS: The survival rate in primary molars is not influenced by the different supply forms of GIC. …”
Publicado 2021
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82637por Xu, Yaqian, Lin, Yanping, Wang, Yaohui, Zhou, Liheng, Xu, Shuguang, Wu, Yifan, Peng, Jing, Zhang, Jie, Yin, Wenjin, Lu, Jinsong“…NeoFHS could serve as an independent predictive factor of pathological complete response (pCR) (OR=2·262, 95% CI 1·159-4·414, p=0·017) and an independent prognostic factor of relapse-free survival (adjusted HR=0·305, 95% CI 0·102-0·910, p=0·033). Alopecia (p=0·001), nausea (p=0·001), peripheral neuropathy (p=0·018), diarrhea (p=0·026), constipation (p=0·037) of any grade and leukopenia of grade 3 or greater (p=0·005) were more common in patients with higher NeoFHS. …”
Publicado 2021
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82638“…Women with a history of PID had a 1.49-fold elevated risk for ovarian cancer (aHR, 1.49; 95% CI, 1.21–1.84; P < 0.001). CONCLUSION: Our study evidence supports the contention that PID increases the risk of developing ovarian cancer among Taiwanese women. …”
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82639por Vaidya, Jayant S., Bulsara, Max, Baum, Michael, Wenz, Frederik, Massarut, Samuele, Pigorsch, Steffi, Alvarado, Michael, Douek, Michael, Saunders, Christobel, Flyger, Henrik, Eiermann, Wolfgang, Brew-Graves, Chris, Williams, Norman R., Potyka, Ingrid, Roberts, Nicholas, Bernstein, Marcelle, Brown, Douglas, Sperk, Elena, Laws, Siobhan, Sütterlin, Marc, Corica, Tammy, Lundgren, Steinar, Holmes, Dennis, Vinante, Lorenzo, Bozza, Fernando, Pazos, Montserrat, Blanc-Onfroy, Magali Le, Gruber, Günther, Polkowski, Wojciech, Dedes, Konstantin J., Niewald, Marcus, Blohmer, Jens, McReady, David, Hoefer, Richard, Kelemen, Pond, Petralia, Gloria, Falzon, Mary, Joseph, David, Tobias, Jeffrey S.“…Non-breast cancer mortality was significantly lower in the TARGIT-IORT arm, even when patients received supplemental EBRT, HR 0.38 (95% CI 0.17–0.88) P = 0.0091. CONCLUSION: TARGIT-IORT is as effective as EBRT in all subgroups. …”
Publicado 2021
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82640“…The baseline demographics and clinical characteristics were comparable between the two arms. The hazard ratio (HR) for time to first bone metastasis was 0.82 (95% CI 0.66–1.02; p = 0.068), with HRs of 0.70 (95% CI 0.52–0.94; p = 0.018) for patients < 50 years old and 0.74 (95% CI 0.55–0.98; p = 0.038) for premenopausal patients, favoring the denosumab group. …”
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