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  1. 82801
    “…Infants < 1 year had significantly inferior 10-yrPFS (5.6%), post-chiasmatic involvement was associated with visual deterioration (HR 2.91, 95%CI=1.1- 7.7), and baseline bilateral abnormal for age vision predicted WHO blindness at follow-up (OR 17.9, 95%CI=3.2 – 101.1). …”
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    LGG-37. Long-term Outcome, Visual Morbidity and Prognostic Factors in Infants and Young Children with Optic Pathway Glioma from the Great Ormond Street Hospital (GOSH) LGG - Cohort
  2. 82802
    “…Kaplan–Meier survival analysis and Immunohistochemistry indicated that overexpression of UBE2S was related to poor prognosis of OV (HR > 1, P < 0.05). Results of in vitro experiments indicated that UBE2S gene knockdown might inhibit the proliferation, invasion, and prognosis of OV cells by inhibiting the PI3K/AKT/mTOR signaling pathway, thereby blocking the cell cycle and promoting apoptosis (P < 0.05). …”
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    UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis
  3. 82803
    “…Multivariate analysis confirmed that patients with 4 or more tumor deposits + the number of lymph node metastases (hazard ratio [HR], 1.88; 95% CI, 1.24–2.87) were independently associated with a shorter RFS. …”
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    Significance of tumor deposits combined with lymph node metastasis in stage III colorectal cancer patients: a retrospective multi-center cohort study from China
  4. 82804
    “…APB(high) gastric cancer exhibited significantly poorer progression-free survival compared with APB(low) (median 55 days vs 121 days, HR 0.40, 95% CI 0.18 to 0.93, p=0.032). CONCLUSION: These findings demonstrate an association between alternate promoter use and the tumour microenvironment, leading to immune evasion and immunotherapy resistance.…”
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    Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition
  5. 82805
    “…Dietary intakes were evaluated using a validated web-based 24hr dietary recall (R24W) repeated on three unannounced occasions. …”
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    Transitioning to Sustainable Dietary Patterns: Learnings From the Dietary Patterns of Adults With Low Animal Protein Consumption in the Province of Quebec
  6. 82806
    “…METHODS: A random sample of 34 dialysis pts was interviewed regarding knowledge about dietary guidelines and 24-hr food recall was recorded and analyzed using ASA-24. …”
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    Poor Nutritional Literacy and Relationship to Dietary Guideline Adherence in Inner-City Dialysis Patients
  7. 82807
    “…Compared with normal-weight adults (BMI 18.5–22.9), the lowest risk of all-cause and cardiovascular mortality was observed among overweight adults (BMI 23.0–24.9: HR [95% CI] = 0.89 [0.83–0.96]; 0.94 [0.79–1.13]; respectively), while for cancer mortality among grade I obesity (BMI 25.0–29.9: 0.91 [0.83–1.01]). …”
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    Obesity and Mortality in a Pooled Analysis of Three Prospective Cohorts of Korean Adults: Is Obesity Paradox the BMI Paradox?
  8. 82808
    “…Patients treated with curative-intent during period C had a survival improvement compared to time period A when adjusting for clinical variables (HR=0.725 (0.632-0.831), p<0.001). CONCLUSION: IMRT was associated with to more patients receiving curative-intent radiotherapy. …”
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    Impact of Introducing Intensity Modulated Radiotherapy on Curative Intent Radiotherapy and Survival for Lung Cancer
  9. 82809
    “…RESULTS: Automated extraction required considerably less time (<1 day) than manual extraction (∼225 person-hr). The collection of demographic data (age, sex, diagnosis) was highly accurate and concordant with both methods (96%–100%). …”
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    Automating Access to Real-World Evidence
  10. 82810
    “…However, an ILA score derived from IPF score genes was associated with ILA (meta-analysis of test datasets OR 1.4 [95% CI: 1.2–1.6]) and mortality (HR 1.25 [95% CI: 1.12–1.41]). Six of the 11 genes in the ILA score had discordant directions of effects compared to the IPF score. …”
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    Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies
  11. 82811
    “…Urinary albumin (mg/gCr) was associated with MACCE in the SMI subgroup [HR 3.37, 95%CI (1.170–9.521), P = 0.025] after adjusting for age, sex, and conventional risk factors. …”
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    Chronic kidney disease is a key predictive factor for potential myocardial ischaemia and poor prognosis in asymptomatic patients with diabetes mellitus
  12. 82812
    “…DpC was an independent risk factor for prognosis (HR = 2.54, 95% CI: 1.32–4.88, P = 0.01). CONCLUSIONS: IDacT had a profound effect on the outcome for stage II-III CRC. …”
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    Irregular delay of adjuvant chemotherapy correlated with poor outcome in stage II-III colorectal cancer
  13. 82813
    “…SEQ-abemaciclib/SpyADI treatment suppressed the DSB repair system via NHEJ and HR, whereas SEQ-dinaciclib/SpyADI treatment increased γ-H2AX accumulation and induced Rad51/Ku80. …”
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    Implementation of a combined CDK inhibition and arginine-deprivation approach to target arginine-auxotrophic glioblastoma multiforme cells
  14. 82814
    “…Additionally, APR users had a lower risk of biologic initiation than MTX users (HR, 0.46 [95% CI, 0.37–0.57]; P < 0.001) during the 1-year follow-up. …”
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    Biologic Initiation Rate in Systemic-Naïve Psoriatic Arthritis Patients Starting Treatment with Apremilast vs Methotrexate: 1-Year Retrospective Analysis of a US Claims Database
  15. 82815
    “…The occurrence of a major complication was the only factor associated with overall survival (HR 2.188 [1.502, 3.188], p< 0.0001). CONCLUSIONS: Despite differences in patient socioeconomic factors and comorbid conditions, outcomes were similar between Black and White patients receiving CRS and HIPEC at our institution. …”
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    Racial Disparities in Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Does Aggressive Surgical Treatment Overcome Cancer Health Inequities?
  16. 82816
    “…Healthy lifestyles were individually associated with 11%–25% reduced risk of ADRD: multivariable-adjusted HR (95% CI) was 0.87 (0.76–0.99) for never vs. current smoking, 0.81 (0.72–0.92) for low-to-moderate vs. no alcohol consumption, 0.89 (0.77–1.03) for ≥150 minutes of moderate or ≥75 minutes of vigorous LTPA per week vs. none, 0.75 (0.64–0.87) for 7–9 hours vs. >9 hours of sleep, and 0.85 (0.75–0.96) for the highest vs. lowest tertiles of Healthy Eating Index. …”
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    Healthy Lifestyles and the Risk of Alzheimer's Disease and Related Dementias among Low-Income Black and White Americans
  17. 82817
    por Okaniwa, Fusae, Yoshida, Hiroshi
    Publicado 2022
    “…RESULTS: Combined AI and video messaging (treatment group II) led to a lower dropout rate from the program compared to the control group, and the Cox proportional-hazards model estimate showed a hazard ratio (HR) of 0.078, which was statistically significant at the 5% level. …”
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    Evaluation of Dietary Management Using Artificial Intelligence and Human Interventions: Nonrandomized Controlled Trial
  18. 82818
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    Analysis of Physicians’ Probability Estimates of a Medical Outcome Based on a Sequence of Events
  19. 82819
    “…RESULTS: ETS was achieved in 82 (64.1%) of 128 mCRC patients treated with first-line cetuximab plus chemotherapy, and these patients had a significantly longer OS than those without ETS (HR, 0.38; 95% CI, 0.20–0.72; P = .002). Asymptomatic patients with ETS had a favorable OS, while symptomatic patients without ETS had a worse OS (2-year OS rates, 77.8% vs. 42.5%). …”
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    Impact of early tumor shrinkage on quality of life in patients treated with first-line cetuximab plus chemotherapy for unresectable metastatic colorectal cancer: results of Phase II QUACK trial
  20. 82820
    “…Prior to and during surgery, the following parameters were recorded in a regular pre-set time interval: onset time of analgesia (OT), duration of flaccid paralysis (DFP), duration of analgesia (DA), onset and duration of sensory blockade, onset and duration of motor blockade, heart rate (HR), respiratory rate (RR), and rectal temperature (RT). …”
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    Antinociceptive effect of lidocaine, tramadol, and their combination for lumbosacral epidural analgesia in rabbits undergoing experimental knee surgery
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