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82861por Haussmann, Jan, Budach, Wilfried, Nestle-Krämling, Carolin, Wollandt, Sylvia, Tamaskovics, Balint, Corradini, Stefanie, Bölke, Edwin, Krug, David, Fehm, Tanja, Ruckhäberle, Eugen, Audretsch, Werner, Jazmati, Danny, Matuschek, Christiane“…Results: For patients with median follow-ups of 20 years, 10 years, 15 years, 20 years, and 25 years, OS rates were 69.7%, 60.6%, 53.1%, and 45.1%, respectively. pCR was achieved in 31.1% of patients and associated with a significant improvement in OS (HR = 0.58; CI-95%: 0.41–0.80; p = 0.001). The prognostic impact of pCR was evident across breast cancer subtypes and chemotherapy regimens. …”
Publicado 2022
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82862por Dantas de Medeiros, Jorge Luiz, Carneiro Bezerra, Bruno, Araújo Cruz, Helen Rainara, Azevedo de Medeiros, Katarina, Cardoso de Melo, Maria Eduarda, Sales Craveiro Sarmento, Aquiles, Abbott Galvão Ururahy, Marcela, Fassarella Agnez Lima, Lucymara, dos Santos Neto, Alcebíades José, Gomes Lima, Josivan, Resqueti, Vanessa, Peroni Gualdi, Lucien, Fregonezi, Guilherme, Araújo de Melo Campos, Julliane Tamara“…RESULTS: At baseline, CGL subjects showed reduced predicted walked distance (6MWD) (p = 0.009) and increased heart rate (HR), systolic (SBP), and diastolic (DBP) pressures compared to healthy subjects (p < 0.05). …”
Publicado 2022
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82863por Yu, Ke-Wei, Li, Bing-Ling, Yuan, Ying-Shi, Liao, Jia-Min, Li, Wei-Kang, Dong, Heng, Ke, Pei-Feng, Jin, Xing, Chen, Lu, Zhao, Jing-Jing, Wang, Heng, Cao, Shun-Wang, Chen, Wei-Ye, Huang, Xian-Zhang, Zhao, Bei-Bei, Kang, Chun-Min“…Clinical data of 83 patients showed that Tac-IPV was associated with poor kidney transplant outcome in Chinese (Hazard Ratio (HR) = 3.96, 4.75; 95% Cl: 1.10–14.21, 1.23–18.36; P < 0.05). …”
Publicado 2022
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82864por Silva, João Paulo Maciel, Coelho, Fabricio Ferreira, Cassenote, Alex Jones Flores, Jeismann, Vagner Birk, Fonseca, Gilton Marques, Kruger, Jaime Arthur Pirola, de Meira Júnior, José Donizeti, Nahas, Sérgio Carlos, Herman, Paulo“…In the multivariate analysis, high PLR was an independent predictor of worse DFS [hazard ratio (HR) 3.029; 95%CI 1.499–6.121; P = 0.002]. CONCLUSION: Inflammatory markers are useful tools to predict long-term outcomes after liver resection in western patients, high NLR was able to stratify subgroups of patients with short OS and DFS, an increased PLR was an independent predictor of short DFS, while high MLR was associated with short OS in patients with early HCC. …”
Publicado 2022
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82865por Wang, Jun, Yang, Biwen, Liu, Meili, You, Tao, Shen, Han, Chen, Yihuan, Huang, Haoyue, Li, Shifeng, Wang, Zhiyang, Li, Xinyue, Huang, Fang, Teng, Xiaomei“…Type A AAD, white blood cell count >10×10(9)/L, platelet count <100×10(9)/L, and serum cystatin C concentration >1.18 mg/L [adjusted hazards ratio (HR) =2.405, 95% confidence interval (CI), 1.029–4.063, P=0.041] were independent risk factors for in-hospital mortality. …”
Publicado 2022
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82866por Ram, Eilon, Fisman, Enrique Z., Tenenbaum, Alexander, Iakobishvili, Zaza, Peled, Yael, Raanani, Ehud, Sternik, Leonid“…While at 2 years of follow-up, survival analysis revealed no differences in mortality risk between the surgical and percutaneous revascularization groups (log-rank p = 0.996), after 2 years CABG was associated with a significant survival benefit (HR 1.53, 95% CI 1.07–2.21; p = 0.021). Comparison of the propensity score matching pairs also revealed a consistent long-term advantage toward CABG (log-rank p = 0.031). …”
Publicado 2022
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82867por Stalter, Randy M., Amorim, Gustavo, Mocello, A. Rain, Jakait, Beatrice, Shepherd, Bryan E., Musick, Beverly, Bernard, Caitlin, Bukusi, Elizabeth A., Wools‐Kaloustian, Kara, Cohen, Craig R., Yiannoutsos, Constantin T., Patel, Rena C.“…When combining sampling phases, there was little evidence to suggest that the relative hazard of pregnancy among efavirenz‐containing ART users relative to nevirapine‐containing ART changed with length of time on implants: IPW‐adjusted HR of 3.1 (CI: [1.5; 6.4]) at 12 months, 3.4 (CI: [1.8; 6.3]) at 24 months, 3.8 (CI: [1.9; 7.7]) at 36 months and 4.2 (CI: [1.6; 11.1]) at 48 months (interaction p‐value = 0.88). …”
Publicado 2022
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82868por Domen, Andreas, Deben, Christophe, De Pauw, Ines, Hermans, Christophe, Lambrechts, Hilde, Verswyvel, Jasper, Siozopoulou, Vasiliki, Pauwels, Patrick, Demaria, Marco, van de Wiel, Mick, Janssens, Annelies, Hendriks, Jeroen M. H., Van Schil, Paul, Vermorken, Jan B., Vandamme, Timon, Prenen, Hans, Peeters, Marc, Lardon, Filip, Wouters, An“…In multiple Cox proportional hazards (Cox PH) model analysis correcting for age, pTNM stage I–III and adjuvant therapy, a tumoral SS remained a significant prognostic factor for OS (HR =2.03; P=0.014). CONCLUSIONS: The presence of a tumoral SS particularly based on high p16(INK4a) expression significantly affects OS in NSCLC adenocarcinoma. …”
Publicado 2022
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82869por Ji, Xiaoyu, Liang, Weili, Lv, Guixu, Ding, Changyuan, Lai, Hong, Li, Luchuan, Zeng, Qingdong, Lv, Bin, Sheng, Lei“…We calculated the odds ratio (OR) or hazard ratio (HR), its corresponding 95% credible intervals (CrI), and the surface under the cumulative ranking curve (SUCRA) to indicate ranking probability using Bayesian network meta-analyses. …”
Publicado 2022
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82870por Neches García, Victoria, Vallejo-Aparicio, Laura Amanda, Ismaila, Afisi S, Sicras-Mainar, Antoni, Sicras-Navarro, Aram, González, Cruz, Cuervo, Rafael, Shukla, Soham, García-Peñuela, Marcos“…Median time to first exacerbation was shorter in patients with ICS withdrawal compared with those continuing ICS (HR: 0.69, 95% CI: 0.57–0.83; p<0.001). Mean health cost per patient/year among patients with ICS withdrawal was higher than those continuing TT (€2993 vs €2130; p<0.001). …”
Publicado 2022
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82871por Li, Yunling, Wang, Guokun, Wang, Xueying, Li, Ye, Zhao, Yanming, Gu, Xia, Xu, Bing, Cui, Jinjin, Wang, Xuedong, Sun, Yong, Liu, Shengliang, Yu, Bo“…Over a median follow-up period of 263 (227–238) days, prevalence of MACEs was significantly higher in the < median MSI group [HR: 0.15 (0.04–0.62); Log-rank P = 0.008]. The univariate Cox regression analysis revealed that LVEF, IS, and MSI were significant predictors for major adverse cardiovascular events (MACEs) (all P < 0.05). …”
Publicado 2022
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82872por Safi, Mohammed, Jin, Chenxing, Aldanakh, Abdullah, Feng, Ping, Qin, Henan, Alradhi, Mohammed, Zhang, Lizhi, Zhang, Junying, Adlat, Salah, Zhao, Yi, Liu, Jiwei“…At 1, 3, and 5 years (79%, 76%, and 76%, respectively), we investigate TNFRFS4 gene and age prediction using novel nomogram-associated aging (HR = 1.79, P 0.001, CI = 1.32–2.45) with higher sensitivity testing.TNFRSF4 gene expression was significantly high in younger (15 years interval) MM patients (P < 0.001). …”
Publicado 2022
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82873por Kammerlander, Andreas, Lyass, Asya, Mahoney, Taylor F., Taron, Jana, Eslami, Parastou, Lu, Michael T., Long, Michelle T., Vasan, Ramachandran S., Massaro, Joseph M., Hoffmann, Udo“…OR 0.68 [0.55, 0.84] and HR 0.73 [0.57, 0.92] for incident hypertension and CVD events, respectively) after adjustment for age, sex, body mass index, and waist circumference. …”
Publicado 2022
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82874por Wu, Dan, Chen, Mengya, Chen, Shile, Zhang, Shimin, Chen, Yongheng, Zhao, Qian, Xue, Ke, Xue, Feng, Chen, Xiaosong, Zhou, Min, Li, Hao, Zheng, Jie, Le, Yunchen, Cao, Hua“…Multiple Cox regression analyses identified ln(Kyn/Trp) (HR 4.874, 95% CI 1.105–21.499, P = 0.036) as an independent prognostic predictor of mortality in DM. …”
Publicado 2022
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82875por Giladi, Odil, Bagnato, Gianmarco, Gentilini, Marianna, Shimony, Shai, Pasvolsky, Oren, Berger, Tamar, Itchaki, Gilad, Raanani, Pia, Broccoli, Alessandro, Stefoni, Vittorio Stefoni, Lolli, Ginevra, Argnani, Lisa, Zinzani, Pier Luigi, Gurion, Ronit“…In multivariate analysis, age was the only independent prognostic factor (HR 1.08, 95% CI 1.03–1.14; P<0.001). Conclusions: In both cohorts, patients' characteristics were comparable between the periods. …”
Publicado 2022
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82876por Ahmadi, Matthew N., Lee, I-Min, Hamer, Mark, del Pozo Cruz, Borja, Chen, Li Jung, Eroglu, Elif, Lai, Yun-Ju, Ku, Po Wen, Stamatakis, Emmanuel“…RESULTS: Compared to stable-insufficient physical activity, increasing physical activity from any baseline level was associated with lower ACM (HR [95%CI]): 0.85 [0.74, 0.96]) and CVD mortality (0.72 [0.55, 0.93]) risk. …”
Publicado 2022
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82877por Chen, Pengfei, Chen, Zhuhong, Pan, Deng, Miao, Lina, Shi, Yujiao, Guo, Ming, Du, Jianpeng“…Meta-analysis indicated that patients with AF ablation had a lower risk of dementia incidence in comparison to patients with AF without ablation [hazard ratio (HR): 0.60, 95% CI: 0.43 to 0.84, p = 0.003 I(2) = 40%]. …”
Publicado 2022
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82878por Chen, Meiting, Chen, Yungchang, Fang, Xiaojie, Wang, Zhao, Pu, Xingxiang, Liang, Chaoyong, Guo, Hongqiang, Li, Qian, Pan, Fei, Hong, Huangming, Huang, He, Li, Jiman, Lin, Tongyu“…Among relapsed or metastatic cases receiving chemotherapy, patients who received immunotherapy at any time presented with a superior OS than those without immunotherapy (P < 0.0001, HR = 0.39, 95% CI 0.25–0.63). Compared with the SEER database, patients with LELC had a better prognosis than NPC, with a 5-year overall survival of 77.3% vs. 56.8% (P < 0.001). …”
Publicado 2022
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82879“…The jockeys were instrumented with heart rate (HR) monitors, accelerometers, and integrated EMG clothing (recording eight muscle groups: quadriceps, hamstrings, gluteal, erector spinae/lower back, abdominal external obliques, abdominal, trapezial and pectoral) which recorded continuously whilst riding. …”
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82880“…Over 19 months, 335 patients on abaloparatide and 375 on teriparatide had a NVF (hazard ratio [95% confidence interval]: 0.89 [0.77, 1.03]), and 121 and 154 patients, respectively, had a hip fracture [HR (95% CI): 0.78 (0.62, 1.00)]. The MACE and MACE + HF rates were similar between cohorts. …”
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