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82921por Faya, Marines, Tuna, Kubra, Ngo, Thu, Abdelmasih, Randa, Torres, Humberto, Reed, Justin“…Given resistant hypokalemia, plasma renin activity and serum aldosterone levels were ordered and revealed to be 0.771ng/mL/hr. and 24.4ng/dL with a ratio >20 (31.26). The patient was started on spironolactone, and CT abdomen and pelvis with contrast revealed a 1.8cm nodule of the left adrenal. …”
Publicado 2022
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82922por Faya, Marines, Tuna, Kubra, Ngo, Thu, Abdelmasih, Randa, Torres, Humberto, Reed, Justin“…Given resistant hypokalemia, plasma renin activity and serum aldosterone levels were ordered and revealed to be 0.771ng/mL/hr. and 24.4ng/dL with a ratio >20 (31.26). The patient was started on spironolactone, and CT abdomen and pelvis with contrast revealed a 1.8cm nodule of the left adrenal. …”
Publicado 2022
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82923por Xu, Tai, Zhang, Si-Ming, Wu, He-Ming, Wen, Xiao-Min, Qiu, Dong-Qin, Yang, Yu-Yang, Wang, Li-Zhen, Zhu, Wen-Biao, He, Li-Shan, Li, Jian-Juan“…RESULTS: Compared with PNI-lowest cases, patients with highest PNI showed significantly longer DFS (multivariate adjusted hazard ratio [HR] = 0.37, 95% confident interval [CI] 0.19–0.70, P for trend = 0.002), whereas higher PLR seemed to be marginally associated with poorer DFS (P for trend = 0.086 and 0.074, respectively). …”
Publicado 2022
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82924por Zhang, Xiaoyun, Xu, Shuo, Wang, Jiaqi, Lv, Yalei, Wang, Na, Lai, Ruixue, Sha, Ziyue, Zhao, Qun, Guo, Zhanjun“…Multivariate analysis also demonstrated irAE (HR = 0.269, 95%CI: 0.088 to 0.822, p = 0.021) were associated independently with the better prognosis for AGC patients. …”
Publicado 2022
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82925por Noor, Fadila, Ogunleye, Olushola O, Ajibola, Oluwafemi, Malik, Shuja, Cluzet, Valerie“…At presentation, he was afebrile (98.5 °F), hypertensive (177/108 mmHg), tachycardic (HR 118 bpm), and saturating 100% on room air. Labs were significant for leukocytosis with 15.1 × 103 WBCs/mcL, elevated creatinine (1.46 g/dL), brain natriuretic peptide (BNP) of 156, troponin of 4 ng/mL that peaked at 16.28 ng/mL. …”
Publicado 2022
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82926por Lee, CH, Wu, MZ, Lui, DTW, Fong, CHY, Ren, QW, Yu, SY, Yuen, MMA, Chow, WS, Huang, JY, Xu, A, Yiu, KH, Lam, KSL“…Baseline serum TSP2 levels were independently associated with the development of HHF (HR 1.31, 95%CI 1.06–1.62, p = 0.014) after adjustments for baseline conventional cardiovascular risk factors, atrial fibrillation, estimated glomerular filtration rate, albuminuria and high-sensitivity C-reactive protein level, use of angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, loop-diuretics, aspirin, insulin, metformin and sodium-glucose co-transporter 2 inhibitors. …”
Publicado 2022
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82927por Ditsatham, Chagkrit, Sripan, Patumrat, Chaiwun, Benjaporn, Klunklin, Pitchayaponne, Tharavichitkul, Ekkasit, Chakrabandhu, Somvilai, Muangwong, Pooriwat, Chitapanarux, Imjai“…Triple negative subtype increased overall mortality in advanced staging (stages III and IV) (aHR:1.42, 95% CI: 0.96–2.11). The 5-year overall survival rate was found in luminal A-like at 82.8%, luminal B-like at 77.6%, HER-2 enriched at 66.4% and triple negative subtype at 64.2%. …”
Publicado 2022
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82928por Sasso, Ferdinando Carlo, Simeon, Vittorio, Galiero, Raffaele, Caturano, Alfredo, De Nicola, Luca, Chiodini, Paolo, Rinaldi, Luca, Salvatore, Teresa, Lettieri, Miriam, Nevola, Riccardo, Sardu, Celestino, Docimo, Giovanni, Loffredo, Giuseppe, Marfella, Raffaele, Adinolfi, Luigi Elio, Minutolo, Roberto“…Cox model showed a significant higher risk of MACE and death in the high-risk group after adjustment for confounding variables, including treatment arm (HR 1.91, 95% CI 1.04–3.52, P = 0.038 and 1.96, 95%CI 1.02–3.8, P = 0,045, respectively, vs absent/low risk group). …”
Publicado 2022
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82929por Trickey, Adam, Zhang, Lei, Gill, M John, Bonnet, Fabrice, Burkholder, Greer, Castagna, Antonella, Cavassini, Matthias, Cichon, Piotr, Crane, Heidi, Domingo, Pere, Grabar, Sophie, Guest, Jodie, Obel, Niels, Psichogiou, Mina, Rava, Marta, Reiss, Peter, Rentsch, Christopher T, Riera, Melchor, Schuettfort, Gundolf, Silverberg, Michael J, Smith, Colette, Stecher, Melanie, Sterling, Timothy R, Ingle, Suzanne M, Sabin, Caroline A, Sterne, Jonathan A C“…However, mortality was higher for raltegravir compared with dolutegravir (aHR 1·49, 95% CI 1·15–1·94), elvitegravir (1·86, 1·43–2·42), rilpivirine (1·99, 1·49–2·66), darunavir (1·62, 1·33–1·98), and efavirenz (2·12, 1·60–2·81) regimens. …”
Publicado 2022
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82930“…However, only E2F7 was closely related to OS [HR =1.91 (1.16–3.16), P=0.011]. CONCLUSIONS: We discover that E2F7 is a prognostic biomarker. …”
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82931por Koh, Sung Min, Chung, Se Hwa, Yum, Yun Jin, Park, Se Jun, Joo, Hyung Joon, Kim, Yong-Hyun, Kim, Eung Ju“…After the multivariable analysis with further adjustment for potential residual confounding factors, the high CV was suggested as an independent risk predictor for MAE (HR 1.19 [95% CI 1.03–1.37]). CONCLUSION: Visit-to-visit variability of triglyceride rather than their cumulative exposure is more strongly related to the incidence of MAE in diabetic patients. …”
Publicado 2022
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82932por Herold, Alexander, Wassipaul, Christian, Weber, Michael, Lindenlaub, Florian, Rasul, Sazan, Stift, Anton, Stift, Judith, Mayerhoefer, Marius E., Hacker, Marcus, Ba-Ssalamah, Ahmed, Haug, Alexander R., Tamandl, Dietmar“…In the survival analysis, MTV was independently associated with overall survival (HR 1.05 [95% CI 1.01–1.10], p = 0.044). CONCLUSION: Multiparametric PET-MRI can improve identification of locally advanced tumors and, hence, help in treatment stratification. …”
Publicado 2022
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82933por Manera, Karine Estelle, Stamatakis, Emmanuel, Huang, Bo-Huei, Owen, Katherine, Phongsavan, Philayrath, Smith, Ben J“…RESULTS: Social isolation amplified the risk of both all-cause and CVD death across all physical activity and sedentary levels (hazard ratio, 95% confidence interval [HR, 95% CIs] for all-cause mortality; 1.58 [1.49 to 1.68] for low active-isolated vs. 1.26 [1.22 to 1.30] for low active-not isolated). …”
Publicado 2022
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82934por Gogishvili, Miranda, Melkadze, Tamar, Makharadze, Tamta, Giorgadze, Davit, Dvorkin, Mikhail, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, Gessner, Christian, Moreno-Jaime, Brizio, Passalacqua, Rodolfo, Li, Siyu, McGuire, Kristina, Kaul, Manika, Paccaly, Anne, Quek, Ruben G. W., Gao, Bo, Seebach, Frank, Weinreich, David M., Yancopoulos, George D., Lowy, Israel, Gullo, Giuseppe, Rietschel, Petra“…The trial was stopped early per recommendation of the independent data monitoring committee, based on meeting preset OS efficacy criteria: median OS was 21.9 months (95% confidence interval (CI), 15.5–not evaluable) with cemiplimab plus chemotherapy versus 13.0 months (95% CI, 11.9–16.1) with placebo plus chemotherapy (hazard ratio (HR) = 0.71; 95% CI, 0.53–0.93; P = 0.014). Grade ≥3 adverse events occurred with cemiplimab plus chemotherapy (43.6%, 136/312 patients) and placebo plus chemotherapy (31.4%, 48/153 patients). …”
Publicado 2022
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82935por Ding, Tian-Yan, Peng, Yu-Hui, Hong, Chao-Qun, Huang, Bin-Liang, Liu, Can-Tong, Luo, Yun, Chu, Ling-Yu, Zhang, Biao, Li, Xin-Hao, Qu, Qi-Qi, Xu, Yi-Wei, Wu, Fang-Cai“…Cox multivariate analysis revealed that serum IGFBP3 was an independent prognostic factor (HR = 0.468, P = 0.005). Compared with TNM stage, a nomogram based on serum IGFBP3, tumor size and TNM stage indicated an improved C-index in prognostic prediction (0.625 vs. 0.735, P = 0.001). …”
Publicado 2022
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82936por Kimanga, Davies O., Oramisi, Violet A., Hassan, Amin S., Mugambi, Mary K., Miruka, Frederick O., Muthoka, Kennedy J., Odhiambo, Jacob O., Yegon, Peter K., Omoro, Gonza O., Mbaire, Catherine, Masamaro, Kenneth M., Njogo, Susan M., Barker, Joseph L, Ngugi, Catherine N.“…When compared to individuals initiated cART 91+ days after a HIV diagnosis, those initiated cART on the same day of a HIV diagnosis had the highest rate of non-retention (same-day vs. 91+ days; aHR, 1.7 [95% CI: 1.5–2.0], p<0.001). Of those included in the analysis, 5986 (69.6%) had a first viral load test done at a median of 6.3 (IQR, 5.6–7.6) months after cART initiation. …”
Publicado 2022
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82937por Mas-Peiro, Silvia, Faerber, Gloria, Bon, Dimitra, Herrmann, Eva, Bauer, Timm, Bleiziffer, Sabine, Bekeredjian, Raffi, Böning, Andreas, Frerker, Christian, Beckmann, Andreas, Möllmann, Helge, Ensminger, Stephan, Hamm, Christian W., Beyersdorf, Friedhelm, Fichtlscherer, Stephan, Walther, Thomas“…RESULTS: One-year survival was similar (HR [95% CI] for TAVI 1.271 [0.795, 2.031], p = 0.316), with no divergence in Kaplan–Meier curves. …”
Publicado 2022
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82938por Lässing, Johannes, Kwast, S., Bischoff, C., Hölldobler, N., Vondran, M., Falz, R., Busse, M.“…At the second visit, lung diffusion capacity (DL(CO)/V(A), %predicted) did not differ between groups (111.6 ± 11.5 vs. 116.1 ± 11.8%; p = 0.45). HR during comparative stress showed no group differences. …”
Publicado 2022
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82939por Huh, Ji-Won, Kim, Min Jung, Kim, Jaesik, Lee, Hyeon Gwon, Ryoo, Seung-Bum, Ku, Ja-Lok, Jeong, Seung-Yong, Park, Kyu Joo, Kim, Dokyoon, Kim, Jihyun F., Park, Ji Won“…A microbiota-derived hazard score considering the five prognostic bacteria accurately predicted CRC progression in 1000 random subsamples; it outperformed widely accepted clinical biomarkers such as carcinoembryonic antigen and lymphatic invasion, after adjustment for the clinicopathological stage (adjusted HR 2.07 [95% CI, 1.61–2.64], P = 7.8e−9, C-index = 0.78). …”
Publicado 2022
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82940por Schoenherr, Jay W., Gonzalez, Michael, Serrano, Ricardo, Park, Meredith, Lee, Zachary, Cobb, Kathryn, Howard, Christopher, Flynn, David, Li, Quefeng, Grant, Stuart, Bullard, Ty“…The second group (n = 32) received a preoperative interscalene catheter with an initial bolus of 20 mL 0.25% bupivacaine and a 0.2% ropivacaine infusion by an elastomeric pump set at 10 mL/hr for 48 hours. The primary outcome was the difference between preoperative and 48-hour postoperative quality of recovery-15 (QoR-15) scores. …”
Publicado 2022
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