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83221“…Medical records were available for review and demonstrated repeated, persistent hypercalcemia (~12.5-13.4 mg/dL) with no history of normo-calcemia, repeated low urine calciums (31 - 56 mg/24hr), PTH 74-130 pg/ml. Other testing included normal PTH-rp, 25 OH Vitamin D, 1,25 OH Vitamin D, and albumin. …”
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83222“…Vital signs: BP 131/59, HR 97, RR 16, Tmax 103.4, Sat 97%. Neurologic examination revealed episodes of confusion with paraphasic speech errors. …”
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83223“…This was seen after 14 doses of IVP 90mg and 5 doses of ZA over a period of 9 months. 24-hour urine protein was 12gm/24hr. Workup for proteinuria including Hepatitis panel, HIV, RPR, ANA, C3/C4, SPEP were unremarkable. …”
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83224por Demidowich, Andrew, Levine, Jordan, Brady, Sheila, Broadney, Miranda, Yanovski, Jack“…Results: Colchicine significantly reduced inflammatory indices, including hsCRP (-2.8±2.9 vs. 0.4±2.8 mg/L, p=.002), ESR (-5.5±6.4 vs. 0.6±6.3 mm/hr, p=.007), white blood cell count (-1.09±1.23 vs. 0.29±1.16 K/µL, p=.002), and absolute neutrophil count (-1.06±1.05 vs. 0.12±0.93 K/µL, p<.001). …”
Publicado 2019
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83225por Brakta, Soumia, Chorich, Lynn, Kim, Hyung-Goo, Coons, Laurel, Hall, Janet, Korach, Kenneth, Layman, Lawrence“…There were 3 pulses in 8 hr with an LH pulse amplitude of 2.3+/-0.5 IU/L. …”
Publicado 2019
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83226por Chudasama, Yogini V., Khunti, Kamlesh K., Zaccardi, Francesco, Rowlands, Alex V., Yates, Thomas, Gillies, Clare L., Davies, Melanie J., Dhalwani, Nafeesa N.“…Compared to low LTPA, for participants with multimorbidity, HR for mortality was 0.75 (95% CI 0.70–0.80) and 0.65 (0.56–0.75) in moderate and high LTPA groups, respectively. …”
Publicado 2019
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83227por Sheridan Rains, Luke, Marston, Louise, Hinton, Mark, Marwaha, Steven, Craig, Thomas, Fowler, David, King, Michael, Omar, Rumana Z., McCrone, Paul, Spencer, Jonathan, Taylor, Joanne, Colman, Sophie, Harder, Catherine, Gilbert, Eleanor, Randhawa, Amie, Labuschagne, Kirsty, Jones, Charlotte, Stefanidou, Theodora, Christoforou, Marina, Craig, Meghan, Strang, John, Weaver, Tim, Johnson, Sonia“…There was no statistically significant difference in time to acute psychiatric care (the primary outcome) (HR 1.03, 95% CI 0.76, 1.40) between groups. By 18 months, 90 (33%) of participants in the CM group, and 85 (30%) of the control groups had been admitted at least once to an acute psychiatric service. …”
Publicado 2019
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83228por Freitas, Pedro, Ferreira, António Miguel, Arteaga-Fernández, Edmundo, de Oliveira Antunes, Murrilo, Mesquita, João, Abecasis, João, Marques, Hugo, Saraiva, Carla, Matos, Daniel Nascimento, Rodrigues, Rita, Cardim, Nuno, Mady, Charles, Rochitte, Carlos Eduardo“…The amount of LGE was the only independent predictor of outcome (adjusted HR: 1.08; 95% CI: 1.04–1.12; p < 0.001) after adjustment for the HCM Risk-SCD and ACCF/AHA criteria. …”
Publicado 2019
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83229por Yang, Keming, Zhang, Ying, Saito, Eiko, Rahman, Md Shafiur, Gupta, Prakash Chandra, Sawada, Norie, Tamakoshi, Akiko, Gao, Yu-Tang, Koh, Woon-Puay, Shu, Xiao-Ou, Tsuji, Ichiro, Sadakane, Atsuko, Nagata, Chisato, You, San-Lin, Yuan, Jian-Min, Shin, Myung-Hee, Chen, Yu, Pan, Wen-Harn, Pednekar, Mangesh S, Tsugane, Shoichiro, Cai, Hui, Xiang, Yong-Bing, Ozasa, Kotaro, Tomata, Yasutake, Kanemura, Seiki, Sugawara, Yumi, Wada, Keiko, Wang, Renwei, Ahn, Yoon-Ok, Yoo, Keun-Young, Ahsan, Habibul, Chia, Kee Seng, Boffetta, Paolo, Kang, Daehee, Potter, John D, Inoue, Manami, Zheng, Wei, Nan, Hongmei“…The pattern of the association among East Asians and South Asians was similar compared with ≤primary education; HR (95% CI) for all-cause mortality associated with ≥university education was 0.72 (0.63 to 0.81) among 539 724 East Asians (Chinese, Japanese and Korean) and 0.61 (0.54 to 0.69) among 154 710 South Asians (Indians and Bangladeshis). …”
Publicado 2019
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83230por Yoshino, Takayuki, Yamanaka, Takeharu, Oki, Eiji, Kotaka, Masahito, Manaka, Dai, Eto, Tetsuya, Hasegawa, Junichi, Takagane, Akinori, Nakamura, Masato, Kato, Takeshi, Munemoto, Yoshinori, Takeuchi, Shintaro, Bando, Hiroyuki, Taniguchi, Hiroki, Gamoh, Makio, Shiozawa, Manabu, Mizushima, Tsunekazu, Saji, Shigetoyo, Maehara, Yoshihiko, Ohtsu, Atsushi, Mori, Masaki“…Of 1291 patients treated (650 in the 3-month arm and 641 in the 6-month arm), 969 (75%) received the chemotherapy drug CAPOX. The hazard ratio (HR) for DFS of the 3-month arm compared with the 6-month arm was 0.95 (95% CI, 0.76-1.20). …”
Publicado 2019
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83231por Varga, Zsuzsanna, Li, Qiyu, Jochum, Wolfram, Perriard, Ulrike, Rau, Tilman, Tille, Jean-Christoph, Hawle, Hanne, Klingbiel, Dirk, Thuerlimann, Beat, Ruhstaller, Thomas“…. <=10%) in patients with chemotherapy was 0.48 with a 95% confidence interval of [0.19–1.19]. Further, the HR of patients treated without chemotherapy was 3.72 with a 95% confidence interval of [1.16–11.96] (p(interaction)=0.007). …”
Publicado 2019
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83232por Wang, F, Wei, X L, Wang, F H, Xu, N, Shen, L, Dai, G H, Yuan, X L, Chen, Y, Yang, S J, Shi, J H, Hu, X C, Lin, X Y, Zhang, Q Y, Feng, J F, Ba, Y, Liu, Y P, Li, W, Shu, Y Q, Jiang, Y, Li, Q, Wang, J W, Wu, H, Feng, H, Yao, S, Xu, R H“…The TMB-H group showed significant superior OS than the TMB-L group [14.6 versus 4.0 months, HR = 0.48 (96% CI 0.24–0.96), P = 0.038], while PD-L1 overexpression did not correlate with significant survival benefit. …”
Publicado 2019
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83233“…At 12-14 weeks of age a total of 69 control & diabetic rats were subjected to 1 hr middle cerebral artery occlusion (MCAO) or Sham surgery. 3 days post-MCAO, rats that met the pre-set inclusion criteria were administered C21 or saline in drinking water at a dose of 0.12 mg/kg/day Adhesive removal task (ART) & 2-trial Ymaze were utilized to test sensorimotor & cognitive function at baseline as well as 1, 2, 4 and 8 weeks post-stroke. …”
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83234por Ortega, Nancy Elizabeth, Stangl, Bethany L., Soundararajan, Soundarya, Burrell, Shaliciana, Sun, Hui, Schwandt, Melanie L., Ramchandani, Vijay A.“…Experiment: Free access (open-bar) intravenous alcohol self-administration (IV-ASA) using the computer-assisted alcohol infusion system (CAIS) paradigm; Subjects had the choice of pressing a button ad libitum for IV alcohol infusions during the session, neurobehavioral questionnaires were collected throughout the 2.5-hr alcohol infusion session. Primary outcome measures included: Total Rewards, Peak breath alcohol concentration (BrAC) achieved, and Total Ethanol consumed. …”
Publicado 2019
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83235por Fashanu, Oluwaseun E., Zhao, Di, Schneider, Andrea L. C., Rawlings, Andreea M., Sharrett, A. Richey, Lutsey, Pamela L., Gottesman, Rebecca F., Gross, Alden L., Guallar, Eliseo, Alonso, Alvaro, Mosley, Thomas H., Michos, Erin D.“…However, after a median follow-up of 20 years, low 25(OH) D concentrations were associated with increased risk for incident dementia (p = 0.01 for trend across categories), with HR of 1.26 (95% CI 1.06, 1.49) for participants with deficient 25(OH) D, compared to sufficient concentrations. …”
Publicado 2019
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83236por Gonzalez del Castillo, Juan, Wilson, Darius Cameron, Clemente-Callejo, Carlota, Román, Francisco, Bardés-Robles, Ignasi, Jiménez, Inmaculada, Orviz, Eva, Dastis-Arias, Macarena, Espinosa, Begoña, Tornero-Romero, Fernando, Giol-Amich, Jordi, González, Veronica, Llopis-Roca, Ferran“…MR-proADM and NEWS had the strongest association with hospitalisation and the requirement for antibiotic administration, whereas MR-proADM alone had the strongest association with ICU admission (OR [95% CI]: 5.8 [3.1 - 10.8]) and mortality (HR [95% CI]: 3.8 [2.2 - 6.5]). Patient subgroups with high MR-proADM concentrations (≥ 1.77 nmol/L) and low NEWS (< 5 points) values had significantly higher rates of ICU admission (8.1% vs 1.6%; p < 0.001), hospital readmission (18.9% vs. 5.9%; p < 0.001), infection-related mortality (13.5% vs. 0.2%; p < 0.001), and disease progression (29.7% vs. 4.9%; p < 0.001) than corresponding patients with low MR-proADM concentrations. …”
Publicado 2019
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83237por Jung, Audrey Y., Behrens, Sabine, Schmidt, Martina, Thoene, Kathrin, Obi, Nadia, Hüsing, Anika, Benner, Axel, Steindorf, Karen, Chang-Claude, Jenny“…Compared to insufficiently active women, increasingly active women were at lower risk of OM, BCM, and RFS (HR (95%CI) of 0.50 (0.31–0.82), 0.54 (0.30–1.00), 0.58 (0.40–0.84), respectively). …”
Publicado 2019
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83238“…Multivariable logistic regression showed that comparing with A group, the HR for long-term mortality and new onset of dialysis in B group was 1.67 and 1.52 respectively (95%CI 1.09–2.90, p = 0.035; 95%CI 1.14–2.49, p = 0.027). …”
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83239por Li, Ji-Bin, Luo, Sheng, Wong, Martin C. S., Li, Cai, Feng, Li-Fen, Peng, Jian-Hong, Li, Jing-Hua, Zhang, Xi“…Every 5% decrease in BMI was associated with a 27% increase in the risk of all-cause mortality (HR = 1.27, 95% CI: 1.22–1.31, p < 0.001). The results from subgroups showed similar trends. …”
Publicado 2019
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83240por Sheikh, Nissar, Chanda, Arshad, Thaseen, Saher, Mahmood, Zia, Ganaw, Adel, Shallik, Nabil“…Patients were intubated and ventilated, the initial dose of Dex infusion was 0.5 mcg/kg/hr along with either fentanyl or remifentanil infusion. …”
Publicado 2019
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