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83241por Du, Zhen, Zhang, Xi‐Ying, Qu, Shuang‐Quan, Song, Zong‐Bing, Wei, Si‐Wei, Xiang, Zhen, Guo, Qu‐Lian“…Systolic blood pressure, diastolic blood pressure and heart rate were lower in Group D than in Group M after administration of sedative drugs until children left PACU (SBP mean difference [95% CI]: 13.87 [10.30‐17.43], P < 0.001, DBP mean difference [95% CI]: 5.96[3.80‐8.11], P < 0.001, HR mean difference [95% CI]: 10.36 [7.58‐13.13], P < 0.001). …”
Publicado 2019
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83242por Strongman, Helen, Gadd, Sarah, Matthews, Anthony, Mansfield, Kathryn E, Stanway, Susannah, Lyon, Alexander R, dos-Santos-Silva, Isabel, Smeeth, Liam, Bhaskaran, Krishnan“…We observed increased risks of heart failure or cardiomyopathy in patients after ten of 20 cancers, including haematological (adjusted HR 1·94, 1·66–2·25, with non-Hodgkin lymphoma; 1·77, 1·50–2·09, with leukaemia; and 3·29, 2·59–4·18, with multiple myeloma), oesophageal (1·96, 1·46–2·64), lung (1·82, 1·52–2·17) kidney (1·73, 1·38–2·17) and ovarian (1·59, 1·19–2·12). …”
Publicado 2019
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83243por Sadiq, Asma, Bostan, Nazish, Bokhari, Habib, Yinda, Kwe Claude, Matthijnssens, Jelle“…Interestingly, the NSP2 gene of strain PAK419 showed closest relationship with Indian bovine strain (India/HR/B91), suggesting the occurrence of reassortment between human and bovine RVA strains. …”
Publicado 2019
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83244por Sikora, Silvester Alexandro, Poespoprodjo, Jeanne Rini, Kenangalem, Enny, Lampah, Daniel A., Sugiarto, Paulus, Laksono, Ida Safitri, Ahmad, Riris Andono, Murhandarwati, E. Elsa Herdiana“…The risk of recurrences within 28 days after hospital admission was 1.94 times higher (95% CI aHR 1.57–2.39, p < 0.0001) in patients receiving intravenous quinine with follow on oral quinine treatment than in patients treated with DHP after intravenous artesunate therapy. …”
Publicado 2019
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83245por Freisling, Heinz, Viallon, Vivian, Lennon, Hannah, Bagnardi, Vincenzo, Ricci, Cristian, Butterworth, Adam S., Sweeting, Michael, Muller, David, Romieu, Isabelle, Bazelle, Pauline, Kvaskoff, Marina, Arveux, Patrick, Severi, Gianluca, Bamia, Christina, Kühn, Tilman, Kaaks, Rudolf, Bergmann, Manuela, Boeing, Heiner, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Dahm, Christina C., Menéndez, Virginia, Agudo, Antonio, Sánchez, Maria-Jose, Amiano, Pilar, Santiuste, Carmen, Gurrea, Aurelio Barricarte, Tong, Tammy Y. N., Schmidt, Julie A., Tzoulaki, Ioanna, Tsilidis, Konstantinos K., Ward, Heather, Palli, Domenico, Agnoli, Claudia, Tumino, Rosario, Ricceri, Fulvio, Panico, Salvatore, Picavet, H. Susan J., Bakker, Marije, Monninkhof, Evelyn, Nilsson, Peter, Manjer, Jonas, Rolandsson, Olov, Thysell, Elin, Weiderpass, Elisabete, Jenab, Mazda, Riboli, Elio, Vineis, Paolo, Danesh, John, Wareham, Nick J., Gunter, Marc J., Ferrari, Pietro“…Multi-state modelling based on Cox regression was used to compute hazard ratios (HR) and 95% confidence intervals (95% CI) of developing cancer, CVD, or T2D, and subsequent transitions to multimorbidity, in relation to body mass index (BMI), smoking status, alcohol intake, physical activity, adherence to the Mediterranean diet, and their combination as a healthy lifestyle index (HLI) score. …”
Publicado 2020
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83246por Xu, Hua-yan, Yang, Zhi-gang, Zhang, Yi, Peng, Wan-lin, Xia, Chun-chao, Li, Zhen-lin, He, Yong, Xu, Rong, Rao, Li, Peng, Ying, Li, Yu-ming, Gao, Hong-ling, Guo, Ying-kun“…Cox proportional hazard regression models revealed that ECV (hazard ratio [HR] = 1.160, 95% confidence interval: 1.022 to 1.318, p = 0.022) was the only independent predictor of HF in ESRD patients. …”
Publicado 2020
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83247por Heath, Alicia K., Muller, David C., van den Brandt, Piet A., Papadimitriou, Nikos, Critselis, Elena, Gunter, Marc, Vineis, Paolo, Weiderpass, Elisabete, Fagherazzi, Guy, Boeing, Heiner, Ferrari, Pietro, Olsen, Anja, Tjønneland, Anne, Arveux, Patrick, Boutron-Ruault, Marie-Christine, Mancini, Francesca Romana, Kühn, Tilman, Turzanski-Fortner, Renée, Schulze, Matthias B., Karakatsani, Anna, Thriskos, Paschalis, Trichopoulou, Antonia, Masala, Giovanna, Contiero, Paolo, Ricceri, Fulvio, Panico, Salvatore, Bueno-de-Mesquita, Bas, Bakker, Marije F., van Gils, Carla H., Olsen, Karina Standahl, Skeie, Guri, Lasheras, Cristina, Agudo, Antonio, Rodríguez-Barranco, Miguel, Sánchez, Maria-José, Amiano, Pilar, Chirlaque, María-Dolores, Barricarte, Aurelio, Drake, Isabel, Ericson, Ulrika, Johansson, Ingegerd, Winkvist, Anna, Key, Tim, Freisling, Heinz, His, Mathilde, Huybrechts, Inge, Christakoudi, Sofia, Ellingjord-Dale, Merete, Riboli, Elio, Tsilidis, Konstantinos K., Tzoulaki, Ioanna“…Higher intake of alcohol overall was associated with a higher risk of breast cancer (hazard ratio (HR) for a 1 SD increment in intake = 1.05, 95% CI 1.03–1.07), as was beer/cider intake and wine intake (HRs per 1 SD increment = 1.05, 95% CI 1.03–1.06 and 1.04, 95% CI 1.02–1.06, respectively), whereas higher intakes of fibre, apple/pear, and carbohydrates were associated with a lower risk of breast cancer (HRs per 1 SD increment = 0.96, 95% CI 0.94–0.98; 0.96, 95% CI 0.94–0.99; and 0.96, 95% CI 0.95–0.98, respectively). …”
Publicado 2020
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83248por Mallucci, Conor L, Jenkinson, Michael D, Conroy, Elizabeth J, Hartley, John C, Brown, Michaela, Dalton, Joanne, Kearns, Tom, Moitt, Tracy, Griffiths, Michael J, Culeddu, Giovanna, Solomon, Tom, Hughes, Dyfrig, Gamble, Carrol“…FINDINGS: Between June 26, 2013, and Oct 9, 2017, we assessed 3505 patients, of whom 1605 aged up to 91 years were randomly assigned to receive either a standard shunt (n=536), an antibiotic-impregnated shunt (n=538), or a silver shunt (n=531). 1594 had a shunt inserted without evidence of infection at the time of insertion (533 in the standard shunt group, 535 in the antibiotic shunt group, and 526 in the silver shunt group) and were followed up for a median of 22 months (IQR 10–24; 53 withdrew from follow-up). 32 (6%) of 533 evaluable patients in the standard shunt group had a shunt revision for infection, compared with 12 (2%) of 535 evaluable patients in the antibiotic shunt group (cause-specific hazard ratio [csHR] 0·38, 97·5% CI 0·18–0·80, p=0·0038) and 31 (6%) of 526 patients in the silver shunt group (0·99, 0·56–1·74, p=0·96). 135 (25%) patients in the standard shunt group, 127 (23%) in the antibiotic shunt group, and 134 (36%) in the silver shunt group had adverse events, which were not life-threatening and were mostly related to valve or catheter function. …”
Publicado 2019
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83249por Inui, Tomohiko, Kohno, Hiroki, Kawasaki, Yohei, Matsuura, Kaoru, Ueda, Hideki, Tamura, Yusaku, Watanabe, Michiko, Inage, Yuichi, Yakita, Yasunori, Wakabayashi, Yutaka, Matsumiya, Goro“…In this study, the diagnostic performance of 2 major smart watches, Apple Watch Series 3 and Fitbit (FBT) Charge HR Wireless Activity Wristband, each equipped with a PPG sensor, was compared, and the pulse rate data outputted from those devices were analyzed for precision and accuracy in reference to the heart rate data from electrocardiography (ECG) during AF. …”
Publicado 2020
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83250por Vuong, Nguyen Lam, Le Duyen, Huynh Thi, Lam, Phung Khanh, Tam, Dong Thi Hoai, Vinh Chau, Nguyen Van, Van Kinh, Nguyen, Chanpheaktra, Ngoun, Lum, Lucy Chai See, Pleités, Ernesto, Jones, Nick Keith, Simmons, Cameron Paul, Rosenberger, Kerstin, Jaenisch, Thomas, Halleux, Christine, Olliaro, Piero Luigi, Wills, Bridget, Yacoub, Sophie“…Higher CRP levels, exceeding 30 mg/L, also associated with hospitalization (OR 1.37, 95% CI 1.14–1.64) and longer fever clearance time (HR 0.84, 95% CI 0.76–0.93), especially in adults. …”
Publicado 2020
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83251por Zhao, Feng, Wang, Jili, Yu, Hao, Cheng, Xiaofei, Li, Xinke, Zhu, Xuan, Xu, Xiangming, Lin, Jianjiang, Chen, Xin, Yan, Senxiang“…For stage T3/4N + M0 patients, neoadjuvant RT (HR = 0.436; 95% CI, 0.396~0.478; p < 0.001) resulted in significantly longer OS than adjuvant RT and surgery plus chemotherapy (mean survival, 104.47 M, 93.94 M, and 93.62 M, respectively), with better OS observed in these patients than in patients who underwent surgery alone (all p < 0.001, mean survival 54.87 M). …”
Publicado 2020
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83252por Anand, Atul, Cudmore, Sarah, Robertson, Shirley, Stephen, Jacqueline, Haga, Kristin, Weir, Christopher J., Murray, Scott A., Boyd, Kirsty, Gunn, Julian, Iqbal, Javaid, MacLullich, Alasdair, Shenkin, Susan D., Fox, Keith A. A., Mills, Nicholas, Denvir, Martin A.“…The hazard of 12-month all-cause mortality nearly doubled per point increase in CFS after adjustment for age, sex and comorbidity (Hazard Ratio [HR] 1.90, 95% CI 1.47–2.44, p < 0.001). The CFS had good discrimination for mortality by Receiver Operating Characteristic (ROC) curve analysis (Area Under the Curve [AUC] 0.81, 95% CI 0.72–0.89) and enhanced the GRACE estimate (AUC 0.86 vs. 0.80 without CFS, p = 0.04). …”
Publicado 2020
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83253“…Microcurrent therapy rapidly reduced post-treatment numeric rating scale for pain by − 1.2 at 10 mins (p = 0.0076), − 1.6 at 1 hr (p = 0.0007), − 1.9 at 2 hrs (p < 0.0001), − 2.1 at 4 hrs (p < 0.0001), and − 2.1 at 6 hrs (p < 0.0001). …”
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83254por Sugihara, Takahiko, Hasegawa, Hitoshi, Uchida, Haruhito A., Yoshifuji, Hajime, Watanabe, Yoshiko, Amiya, Eisuke, Maejima, Yasuhiro, Konishi, Masanori, Murakawa, Yohko, Ogawa, Noriyoshi, Furuta, Shunsuke, Katsumata, Yasuhiro, Komagata, Yoshinori, Naniwa, Taio, Okazaki, Takahiro, Tanaka, Yoshiya, Takeuchi, Tsutomu, Nakaoka, Yoshikazu, Arimura, Yoshihiro, Harigai, Masayoshi, Isobe, Mitsuaki“…A multivariable model showed the presence of LVLs at baseline was significantly associated with poor treatment outcomes (adjusted hazard ratio [HR] 3.54, 95% CI 1.52–8.24, p = 0.003). Cranial lesions and PMR did not increase the risk of poor treatment outcomes. …”
Publicado 2020
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83255por Godi, Ilaria, De Rosa, Silvia, Martino, Francesca, Bazzano, Simona, Martin, Marina, Boni, Elisa, Carta, Maria Rosa, Tamayo Diaz, Claudia, Mari, Gaia, Lorenzin, Anna, de Cal, Massimo, Corradi, Valentina, Caprara, Carlotta, Giavarina, Davide, Ronco, Claudio“…Moreover, the double-marker positivity showed an elevated risk for AKD at 7 days in non-septic patients (OR 15.9, 95% CI 3,21–73,57, p < 0.001) and for mortality within 7 days in septic patients (HR 4.1, 95% CI 1.4–11.8, p = 0.001). CONCLUSIONS: Although combining the results of [TIMP-2] × [IGFBP7] and PCT may be a useful tool to identify and stratify ICU patients at high risk for septic AKI and short-term adverse outcomes, data should be confirmed in a large prospective study.…”
Publicado 2020
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83256“…In particular, validations are required for diseases-specific population in Bangladesh to measure the Health Related Quality of life (HR-QoL) assessments for people suffering from chronic or other diseases.…”
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83257por Sheikh, Mahdi, Shakeri, Ramin, Poustchi, Hossein, Pourshams, Akram, Etemadi, Arash, Islami, Farhad, Khoshnia, Masoud, Gharavi, Abdolsamad, Roshandel, Gholamreza, Khademi, Hooman, Sepanlou, Sadaf G, Hashemian, Maryam, Fazel, Abdolreza, Zahedi, Mahdi, Abedi-Ardekani, Behnoush, Boffetta, Paolo, Dawsey, Sanford M, Pharoah, Paul D, Sotoudeh, Masoud, Freedman, Neal D, Abnet, Christian C, Day, Nicholas E, Brennan, Paul, Kamangar, Farin, Malekzadeh, Reza“…Use of opium was associated with an increased risk of developing all cancers combined (HR 1·40, 95% CI 1·24–1·58), gastrointestinal cancers (1·31, 1·11–1·55), and respiratory cancers (2·28, 1·58–3·30) in a dose-dependent manner (p(trend)<0·001). …”
Publicado 2020
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83258por Dong, Li, Zhang, Li, Hu, Shang-Ying, Feng, Rui-Mei, Zhao, Xue-Lian, Zhang, Qian, Pan, Qin-Jing, Zhang, Xun, Qiao, You-Lin, Zhao, Fang-Hui“…A methylation panel based on the above six sites showed a competitive risk stratification compared to cytology (HR 11.5 vs. 8.1), with a higher 10-year CIR of CIN3+ in panel positives (57.2% vs 36.8%) and comparable low risk in panel negatives (5.7% vs 4.8%).The sensitivity and specificity for accumulative CIN3+ was 85.7% (95%CI 60.1–96.0%) and 78.4% (95%CI 62.8–88.6%) for a methylation panel and 57.1% (95%CI 32.6–78.6%) and 86.5% (95%CI 72.0–94.1%) for E6 oncoprotein. …”
Publicado 2020
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83259por Cebon, Jonathan S, Gore, Martin, Thompson, John F, Davis, Ian D, McArthur, Grant A, Walpole, Euan, Smithers, Mark, Cerundolo, Vincenzo, Dunbar, P Rod, MacGregor, Duncan, Fisher, Cyril, Millward, Michael, Nathan, Paul, Findlay, Michael P N, Hersey, Peter, Evans, T R Jeffry, Ottensmeier, Christian Hermann, Marsden, Jeremy, Dalgleish, Angus G, Corrie, Pippa G, Maria, Marples, Brimble, Margaret, Williams, Geoff, Winkler, Sintia, Jackson, Heather M, Endo-Munoz, Liliana, Tutuka, Candani S A, Venhaus, Ralph, Old, Lloyd J, Haack, Dennis, Maraskovsky, Eugene, Behren, Andreas, Chen, Weisan“…There were no differences between the study arms in relapses at 18 months or for median time to relapse; 139 vs 176 days (p=0.296), or relapse rate, 27 (48.2%) vs 26 (48.1%) (HR 0.913; 95% CI 0.402 to 2.231), respectively. …”
Publicado 2020
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83260por Nair, Nandini, Vittinghoff, Eric, Pletcher, Mark, Oelsner, Elizabeth, Allen, Norrina, Ndumele, Chiadi, West, Nancy, Strotmeyer, Elsa, Mukamal, Kenneth, Siscovick, David, Biggs, Mary Lou, Laferrère, Blandine, Moran, Andrew, Zhang, Yiyi“…Compared to BMI 18.5–24.9 kg/m(2), hazard ratios (HR) for incident diabetes were 1.27 (95%CI: 1.14–1.41) and 1.99 (95%CI: 1.67–2.37) for BMI 25–29 kg/m(2) and ≥30 kg/m(2), respectively. …”
Publicado 2020
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