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83821por Pezzini, Alessandro, Grassi, Mario, Silvestrelli, Giorgio, Locatelli, Martina, Rifino, Nicola, Beretta, Simone, Gamba, Massimo, Raimondi, Elisa, Giussani, Giuditta, Carimati, Federico, Sangalli, Davide, Corato, Manuel, Gerevini, Simonetta, Masciocchi, Stefano, Cortinovis, Matteo, La Gioia, Sara, Barbieri, Francesca, Mazzoleni, Valentina, Pezzini, Debora, Bonacina, Sonia, Pilotto, Andrea, Benussi, Alberto, Magoni, Mauro, Premi, Enrico, Prelle, Alessandro Cesare, Agostoni, Elio Clemente, Palluzzi, Fernando, De Giuli, Valeria, Magherini, Anna, Roccatagliata, Daria Valeria, Vinciguerra, Luisa, Puglisi, Valentina, Fusi, Laura, Diamanti, Susanna, Santangelo, Francesco, Xhani, Rubjona, Pozzi, Federico, Grampa, Giampiero, Versino, Maurizio, Salmaggi, Andrea, Marcheselli, Simona, Cavallini, Anna, Giossi, Alessia, Censori, Bruno, Ferrarese, Carlo, Ciccone, Alfonso, Sessa, Maria, Padovani, Alessandro“…Patients with COVID-19 had increased stroke severity at admission [median NIHSS score, 9 (25th to75th percentile, 13) vs 6 (25th to75th percentile, 9)] and increased risk of in-hospital death (38.1% deaths vs 7.2%; HR 3.30; 95% CI 2.17–5.02). The RF model based on six clinical and laboratory parameters exhibited high cross-validated classification accuracy (0.86) and precision (0.87), good recall (0.72) and F1-score (0.79) in predicting in-hospital death. …”
Publicado 2021
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83822“…Patients with EGFR mutation-negative and ECOG PS ≤1 had longer PFS, and patients without previous thoracic radiation therapy (HR: 1.855, 95% CI 1.162–2.960; P = 0.010) had shorter OS. …”
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83823por Woo, Joohyun, Oh, Se Jeong, Song, Jeong-Yoon, Chae, Byung Joo, Choi, Jung Eun, Lee, Jeeyeon, Park, Heung Kyu, Lim, Woosung“…In multivariate analysis, young age (< 35 years) was correlated with poor overall survival (P = 0.003, HR = 1.98) and there was only one event in a few patients achieved pCR in ER-positive group. …”
Publicado 2021
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83824por Chen, Chao, Liu, Yan Qun, Qiu, Shi Xiang, Li, Ya, Yu, Ning Jun, Liu, Kang, Zhong, Li Ming“…A risk score based on the signature was a significantly independent prognostic factor (HR = 1.434; 95%CI = 1.275–1.612; P < 0.001) for HCC patients. …”
Publicado 2021
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83825por Haehl, Erik, Rühle, Alexander, Klink, Rabea, Kalckreuth, Tobias, Sprave, Tanja, Gkika, Eleni, Zamboglou, Constantinos, Meiß, Frank, Grosu, Anca-Ligia, Nicolay, Nils H.“…In the multivariate analysis, positive lymph node status remained the only significant prognostic factor deteriorating OS (HR 3.73, CI 1.54–9.03, p < 0.01). Interestingly, neither KPS nor CCI impaired survival in this elderly patient cohort. …”
Publicado 2021
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83826por Bonomo, P., Merlotti, A., Morbelli, S., Berti, V., Saieva, C., Bergesio, F., Bacigalupo, A., Belgioia, L., Franzese, C., Lopci, E., Casolo, A., D’Angelo, E., Alterio, D., Travaini, L., Berretta, L., Pirro, V., Ursino, S., Volterrani, D., Roncali, M., Vigo, F., Cicchetti, S., Scalone, F., Belli, G., Cauda, S., Desideri, I., Russi, E., Livi, L., Bianchi, A.“…A Cuneo score of 5-6 (indicative of residual disease) was associated with poor overall survival at multivariate analysis (HR 6.0; 95% CI, 1.88-19.18; p = 0.002). In addition, nodal progressive disease according to PERCIST criteria was associated with worse LRC (OR for LR failure, 5.65; 95% CI, 1.26-25.46; p = 0.024) and overall survival (OR for death, 4.81; 1.07-21.53; p = 0.04). …”
Publicado 2020
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83827por Wilhelm, Maria-Lisa, Chan, Mark K. H., Abel, Benedikt, Cremers, Florian, Siebert, Frank-Andre, Wurster, Stefan, Krug, David, Wolff, Robert, Dunst, Jürgen, Hildebrandt, Guido, Schweikard, Achim, Rades, Dirk, Ernst, Floris, Blanck, Oliver“…LC did not correlate with any TDR, but tumor response (partial response [PR] or complete response [CR]) correlated with all TDR in univariate analysis (e.g., TDR(60min,98%): hazard ration [HR] = 0.974, confidence interval [CI] = 0.952–0.996, p = 0.019). …”
Publicado 2020
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83828por Di Castelnuovo, Augusto, Gialluisi, Alessandro, Antinori, Andrea, Berselli, Nausicaa, Blandi, Lorenzo, Bonaccio, Marialaura, Bruno, Raffaele, Cauda, Roberto, Costanzo, Simona, Guaraldi, Giovanni, Menicanti, Lorenzo, Mennuni, Marco, My, Ilaria, Parruti, Giustino, Patti, Giuseppe, Perlini, Stefano, Santilli, Francesca, Signorelli, Carlo, Stefanini, Giulio, Vergori, Alessandra, Ageno, Walter, Agodi, Antonella, Agostoni, Piergiuseppe, Aiello, Luca, Al Moghazi, Samir, Arboretti, Rosa, Aucella, Filippo, Barbieri, Greta, Barchitta, Martina, Bonfanti, Paolo, Cacciatore, Francesco, Caiano, Lucia, Cannata, Francesco, Carrozzi, Laura, Cascio, Antonio, Castiglione, Giacomo, Ciccullo, Arturo, Cingolani, Antonella, Cipollone, Francesco, Colomba, Claudia, Colombo, Crizia, Crisetti, Annalisa, Crosta, Francesca, Danzi, Gian Battista, D'Ardes, Damiano, de Gaetano Donati, Katleen, Di Gennaro, Francesco, Di Tano, Giuseppe, D'Offizi, Gianpiero, Fusco, Francesco Maria, Gaudiosi, Carlo, Gentile, Ivan, Gianfagna1, Francesco, Giuliano, Gabriele, Graziani, Emauele, Guarnieri, Gabriella, Langella, Valerio, Larizza, Giovanni, Leone, Armando, Maccagni, Gloria, Magni, Federica, Maitan, Stefano, Mancarella, Sandro, Manuele, Rosa, Mapelli, Massimo, Maragna, Riccardo, Marcucci, Rossella, Maresca, Giulio, Marongiu, Silvia, Marotta, Claudia, Marra, Lorenzo, Mastroianni, Franco, Mengozzi, Alessandro, Meschiari, Marianna, Milic, Jovana, Minutolo, Filippo, Mussinelli, Roberta, Mussini, Cristina, Musso, Maria, Odone, Anna, Olivieri, Marco, Palimodde, Antonella, Pasi, Emanuela, Pesavento, Raffaele, Petri, Francesco, Pivato, Carlo A, Poletti, Venerino, Ravaglia, Claudia, Righetti, Giulia, Rognoni, Andrea, Rossato, Marco, Rossi, Ilaria, Rossi, Marianna, Sabena, Anna, Salinaro, Francesco, Sangiovanni, Vincenzo, Sanrocco, Carlo, Schiano Moriello, Nicola, Scorzolini, Laura, Sgariglia, Raffaella, Simeone, Paola Giustina, Spinicci, Michele, Tamburrini, Enrica, Torti, Carlo, Trecarichi, Enrico Maria, Vettor, Roberto, Vianello, Andrea, Vinceti, Marco, Virdis, Agostino, De Caterina, Raffaele, Iacoviello, Licia“…The latter group was at increased death risk adjusted by HCQ (HR[CI95%] = 3.80[3.08-4.67]), while HCQ showed an independent inverse association (0.51[0.43-0.61]), as well as a significant influence of cluster∗HCQ interaction (p < 0.001). …”
Publicado 2021
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83829por Koohi, Fatemeh, Khalili, Davood, Mansournia, Mohammad Ali, Hadaegh, Farzad, Soori, Hamid“…Even individuals in the multi-trajectory group with the highest HDL-C, optimal LDL-C, and optimal TG levels had a significant risk (HR, 1.45; 95% CI 1.02–2.08). Furthermore, only those with the highest HDL-C profile increased the risk of heart failure by 1.5-fold (95% CI 1.07–2.06). …”
Publicado 2021
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83830por Huang, Bin, Cai, Yun, Li, Ning, Li, Kening, Wang, Zhihua, Li, Lu, Wu, Lingxiang, Zhu, Mengyan, Li, Jie, Wang, Ziyu, Wu, Min, Li, Wanlin, Wu, Wei, Zhang, Lishen, Xia, Xinyi, Wang, Shukui, Chen, Hongshan, Wang, Qianghu“…Survival analysis revealed that the male sex is an independent risk factor for death from COVID-19 (adjusted hazard ratio [HR] = 2.22, 95% confidence interval [CI]: 1.3–3.6, P = 0.003). …”
Publicado 2021
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83831“…The iCa remained mildly elevated at 1.43 mmol/L (1.15–1.3) with a 24 hr urinary CCCR at 0.024 and a mid-normal PTH of 4.4 pmol/L (1.6–6.9). …”
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83832por Edelman, Steven Victor, Conoscenti, Valentina, Junaidi, M Khaled, Close, Nicole, Sequeira, David, Nguyen, Anh“…Results: XP-3924 treatment resulted in a 62.3% reduction of hyperglycemia (blood glucose AUC(0-3 hr) >180 mg/dL) after the glucose challenge when compared to RI (p<0.001), and exhibited comparable postprandial glycemic control to that of the co-administration. …”
Publicado 2021
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83833“…In addition to high doses of oral calcium and calcitriol, he required calcium drip up to 1.5mg/kg/hr for about 1 week. He simultaneously began cabozantinib, ketoconazole and metyrapone. …”
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83834por Carvalho, Anna Cristina C., Amorim, Gustavo, Melo, Mayla G. M., Silveira, Ana Karla A., Vargas, Pedro H. L., Moreira, Adriana S. R., Rocha, Michael S., Souza, Alexandra B., Arriaga, María B., Araújo-Pereira, Mariana, Figueiredo, Marina C., Durovni, Betina, Lapa-e-Silva, José R., Cavalcante, Solange, Rolla, Valeria C., Sterling, Timothy R., Cordeiro-Santos, Marcelo, Andrade, Bruno B., Silva, Elisangela C., Kritski, Afrânio L.“…In addition, adjusted Cox regression found that higher baseline neutrophil count (10(3)/mm(3)) was associated with unfavorable treatment outcomes overall and among HIV-seronegative patients (HR= 1.16 (95% CI = [1.05;1.27]). CONCLUSION: Increased neutrophil count prior to anti-TB treatment initiation was associated with unfavorable treatment outcomes, particularly among HIV-seronegative patients. …”
Publicado 2021
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83835“…The risk score, which developed from ten radiomics signatures model, was found to be independent of age, gender, and stage for predicting overall survival in NSCLC patients (HR, 2.99; 95% CI, 2.27–3.93; p < 0.001) and overall survival prediction ability was 0.696 (95% CI, 0.635–0.758), 0.705 (95% CI, 0.649–0.762), 0.657 (95% CI, 0.589–0.726) (AUC) for 1, 3, and 5 years, respectively, in the training set. …”
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83836por Yates, Thomas, Zaccardi, Francesco, Islam, Nazrul, Razieh, Cameron, Gillies, Clare L., Lawson, Claire A., Chudasama, Yogini, Rowlands, Alex, Davies, Melanie J., Docherty, Annemarie B., Openshaw, Peter J. M., Baillie, J. Kenneth, Semple, Malcolm G., Khunti, Kamlesh“…Under 50 years of age, obesity and chronic disease were associated with in-hospital mortality within 28 days of admission in a dose-response manner, such that patients with both obesity and chronic disease had the highest risk with a hazard ratio (HR) of in-hospital mortality of 2.99 (95% CI: 2.12, 4.21) in men and 2.16 (1.42, 3.26) in women compared to patients without obesity or chronic disease. …”
Publicado 2021
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83837por Fan, Bo, Mohammed, Alradhi, Huang, Yuanbin, Luo, Hong, Zhang, Hongxian, Tao, Shenghua, Xu, Weijiao, Liu, Qian, He, Tao, Jin, Huidan, Sun, Mengfan, Sun, Man, Yun, Zhifei, Zhao, Rui, Wu, Guoyu, Li, Xiancheng“…However, in people younger than 68, aspirin intake seemed to have prolonged effects for overall survival (HR=3.876; 95% CI=1.326-11.325, P=0.019). Then, we performed a meta-analysis and the combined results from 19 articles and our study involving more than 39524 BCa cases indicated that aspirin intake was not associated with the occurrence of BCa (P=0.671). …”
Publicado 2021
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83838por Seol, Hee Yun, Shrestha, Pragya, Muth, Joy Fladager, Wi, Chung-Il, Sohn, Sunghwan, Ryu, Euijung, Park, Miguel, Ihrke, Kathy, Moon, Sungrim, King, Katherine, Wheeler, Philip, Borah, Bijan, Moriarty, James, Rosedahl, Jordan, Liu, Hongfang, McWilliams, Deborah B., Juhn, Young J.“…Among those who experienced the first AE during the study period (n = 25), those in the intervention group had timelier follow up by the clinical care team compared to those in the control group but no significant difference was found (HR = 1.93; 95% CI: 0.82–1.45, P = 0.10). There was no difference in the proportion of duration when patients had well-controlled asthma during the study period between the intervention and the control groups. …”
Publicado 2021
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83839“…SMR’s for total mortality of males and females with less than 8 years of education compared to 16 and over were 2.2 and 1.8, respectively. Corresponding HR were 2.13 (95% CI 2.08–2.18) and 1.77 (95% CI 1.72–1.82), respectively. …”
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83840por Złowocka-Perłowska, Elżbieta, Dębniak, Tadeusz, Słojewski, Marcin, van de Wetering, Thierry, Tołoczko-Grabarek, Aleksandra, Cybulski, Cezary, Scott, Rodney J., Lubiński, Jan“…However, we observed a possible increased survival in the subgroup of patients with stage T1 bladder cancer with CHEK2 mutations but this did not meet statistical significance (HR = 0.14; 95% CI 0.02–1.04; p = 0.055). Moreover, we observed that the missense mutations were more frequent in the low grade invasive bladder cancer patient group (OR = 7.9; 95% CI 1.50–42.1; p = 0.04) and in patients with bladder cancer with stage Ta (OR = 2.4; 95% CI 1.30–4.55; p = 0.006). …”
Publicado 2021
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