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83981“…INTRODUCTION: Burn shock resuscitation fluids should be titrated to achieve a urine output (UOP) of 0.5 to 1 mL/kg/hr. It is unknown whether this UOP goal should be indexed to actual body weight (ABW) or predicted body weight (PBW). …”
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83982por Qiao, Xiang-Rui, Zheng, Tao, Xie, Yifei, yao, Xinyi, Yuan, Zuyi, Wu, Yue, Zhou, Dong, Chen, Tao“…MiR-146a rs2910164 polymorphism in dominant model was associated with the incidence of MACE in post-PCI patients (CG + GG vs. CC, HR = 1.405, 95% CI (1.018–1.939), P = 0.038). However, the miR-34b rs4938723 polymorphism was not associated with the prevalence and prognosis of ACS. …”
Publicado 2023
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83983por de Bakker, Marie, Petersen, Teun B., Akkerhuis, K. Martijn, Harakalova, Magdalena, Umans, Victor A., Germans, Tjeerd, Caliskan, Kadir, Katsikis, Peter D., van der Spek, Peter J., Suthahar, Navin, de Boer, Rudolf A., Rizopoulos, Dimitris, Asselbergs, Folkert W., Boersma, Eric, Kardys, Isabella“…Endothelin-1 was more strongly associated with the PEP in men (HR 2.62 [95%CI, 1.98, 3.46], p < 0.001) compared to women (1.14 [1.01, 1.29], p = 0.036). …”
Publicado 2023
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83984por Zhang, Shu, Otsuka, Rei, Nishita, Yukiko, Tange, Chikako, Tomida, Makiko, Ando, Fujiko, Shimokata, Hiroshi, Arai, Hidenori“…The multivariate-adjusted HR (95% CI) and 11th PDs (95% CI) in age at incident dementia for participants in the T1 vs. …”
Publicado 2023
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83985por Chudzik, M, Babicki, M, Kapusta, J, Kolat, D, Kaluzinska-Kolat, Z, Mastalerz-Migas, A, Jankowski, P“…Following parameters were analysed: 1. in ECG: mean heart rate (mHR); PQ interval (PQ), QRS duration (QRSd); corrected QT interval (QTc); atrial fibrillation (AF); inappropriate sinus tachycardia (ITS), QRS duration > 120ms (QRS>120); LBBB, RBBB, QRS fragmentation (QRSf); STT wave abnormalities (STTabn); presence of premature supraventricular (SVES) and ventricular (VES) complexes; 2. in 24-h Holter ECG: sinus tachycardia (STach), new atrial fibrillation (AFHolter), SVES > 1000/24h (SVES>1000); supraventricular tachycardia (TSV), VES > 1000/24h (VES>1000), Couplet VES (VEScouplet), non-sustained ventricular tachycardia (nsVT); ventricular tachycardia (VT), block A-V 2nd typ 2 and/or block A-V 3rd grade (AVdist). …”
Publicado 2023
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83986por Chudzik, M, Babicki, M, Kapusta, J, Kolat, D, Kaluzinska-Kolat, Z, Mastalerz-Migas, A, Jankowski, P“…Following parameters were analysed in ECG: mean heart rate (mHR); PQ interval (PQ), QRS duration (QRSd); corrected QT interval (QTc); atrial fibrillation (AF); inappropriate sinus tachycardia (ITS), QRS duration > 120ms (QRS>120); LBBB, RBBB, QRS fragmentation (QRSf); STT wave abnormalities (STTabn); presence of premature supraventricular (SVES) and ventricular (VES) complexes; in 24-h Holter ECG: sinus tachycardia (STach), new atrial fibrillation (AFHolter), SVES > 1000/24h (SVES>1000); supraventricular tachycardia (TSV), VES > 1000/24h (VES>1000), Couplet VES (VEScouplet), non-sustained sustained tachycardia (nsVT); ventricular tachycardia (VT), block A-V 2nd typ 2 and/or block A-V 3rd grade (AVdist). …”
Publicado 2023
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83987por Bhagirath, P, Campos, F O, Zaidi, H A, Chen, Z, Elliott, M, Gould, J, Prassl, A J, Neic, A, Plank, G, Rinaldi, C A, Bishop, M J“…Cox-regression demonstrated a significant independent association of myocardium-total enhancement interface with an event (HR 2.79; 1.44-5.44, p < .01). Kaplan-Meier analysis showed a significantly higher event rate in patients with an interface area between myocardium-total enhancement of more than 72cm2 (Figure 1A) and BZ-core more than 42.3cm2 (Figure 1B). …”
Publicado 2023
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83988por Schlichting, A, Senges, J, Hochadel, M, Thomas, D, Voss, F, Straube, F, Bonaventura, K, Leschke, M, Zrenner, B, Becker, R, Willems, S, Hakmi, S“…There were no differences in neither device-associated complications requiring revision (15.0 vs. 19.1%, p=0.52), nor in all-cause mortality (3.7 vs. 1.9%, p=0.52; HR 0.5, 95%CI: 0.06-4.27) after 1-year of follow-up, but female patients had a higher mean number of rehospitalizations (1.6±1.5 vs. 2.1±1.3; p=0.026). …”
Publicado 2023
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83989por Yin, Xin, Wang, Jingwen, Xu, Zhibo, Qian, Fuyong, Liu, Songbin, Cai, Yuxi, Jiang, Zhaoshun, Zhang, Xixue, Gu, Weidong“…The 6MWD was measured for all patients before surgery. e[Formula: see text] O(2max) was calculated using the regression model of Burr, which uses 6MWD, age, gender, weight, and resting heart rate (HR) to predict aerobic fitness. The patients were categorized into PPC and non-PPC group. …”
Publicado 2023
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83990por Weng, Hong, Xiong, Kang-Ping, Wang, Wang, Qian, Kai-Yu, Yuan, Shuai, Wang, Gang, Yu, Fang, Luo, Jun, Lu, Meng-Xin, Yang, Zhong-Hua, Liu, Tao, Huang, Xing, Zheng, Hang, Wang, Xing-Huan“…The expression of ASPA was found to be significantly down-regulated in PCa tissue samples, and its decreased expression was independently associated with patients’ prognosis (HR = 0.60, 95% CI 0.40–0.92, P = 0.018). Our experiments demonstrated that modulation of ASPA activity, either through gain- or loss-of-function, led to the suppression or enhancement of PCa cell proliferation, migration, and invasion, respectively. …”
Publicado 2023
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83991por Kaboré, Nongodo Firmin, Ouédraogo, Samiratou, Mamguem, Ariane Kamga, Traoré, Isidore Tiandiogo, Kania, Dramane, Badolo, Hermann, Sanou, Guillaume, Koné, Amariane, Yara, Mimbouré, Kagoné, Thérèse, Ouédraogo, Esperance, Konaté, Blahima, Médah, Rachel, de Rekeneire, Nathalie, Poda, Armel, Diendéré, Arnaud Eric, Ouédraogo, Boukary, Billa, Oumar, Paradis, Gilles, Dabakuyo-Yonli, Tienhan Sandrine, Tinto, Halidou“…Multivariable analysis showed that participants aged 19 years and older were almost twice as likely to seroconvert during the study period compared with those aged 10 to 18 years (Hazard ratio: HR = 1.7 [1.3–2.3], p < 0.001). Those aged 10–18 years exhibited more asymptomatic forms than those aged 19 years and older, among those who achieved seroconversion (72.9% vs. 40.4%, p < 0.001). …”
Publicado 2023
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83992por Ding, Rongxiu, Ding, Pan, Tian, Liuhong, Kuang, Xiaodan, Huang, Li, Shi, Hongying“…Threshold analysis indicated a sharply increased risk of mortality in participants whose sleep exceeds 9 h (HR = 1.20, 95%CI: 1.11, 1.30). CONCLUSION: Compared with the persistent sleep trajectory of 7 h, moderately and rapidly increased sleep duration trajectories were associated with higher subsequent mortality in Chinese elderly. …”
Publicado 2023
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83993por Yerrakalva, Dharani, Hajna, Samantha, Suhrcke, Marc, Wijndaele, Katrien, Westgate, Kate, Khaw, Kay-Tee, Wareham, Nick, Brage, Soren, Griffin, Simon“…More pronounced declines in activity were associated with worse Hr-QoL (0.005 (95% CI 0.003, 0.008) lower EQ-5D per min/day/yr decrease in MVPA). …”
Publicado 2023
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83994por Docherty, Annemarie B, Farrell, James, Thorpe, Mathew, Egan, Conor, Dunn, Sarah, Norman, Lisa, Shaw, Catherine A, Law, Andrew, Leeming, Gary, Norris, Lucy, Brooks, Andrew, Prodan, Bianca, MacLeod, Ruairidh, Baxter, Robert, Morris, Carole, Rennie, Diane, Oosthuyzen, Wilna, Semple, Malcolm G, Baillie, J Kenneth, Pius, Riinu, Seth, Sohan, Harrison, Ewen M, Lone, Nazir I“…Compared with the no admissions group, mortality was highest in the recently high admissions group (post-hospital mortality HR 2·70 [95% CI 2·35–2·81]; p<0·0001) and the risk of readmission was highest in the persistently high admissions group (3·23 [2·89–3·61]; p<0·0001). …”
Publicado 2023
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83995por Nikulin, Pavel, Zschaeck, Sebastian, Maus, Jens, Cegla, Paulina, Lombardo, Elia, Furth, Christian, Kaźmierska, Joanna, Rogasch, Julian M. M., Holzgreve, Adrien, Albert, Nathalie L., Ferentinos, Konstantinos, Strouthos, Iosif, Hajiyianni, Marina, Marschner, Sebastian N., Belka, Claus, Landry, Guillaume, Cholewinski, Witold, Kotzerke, Jörg, Hofheinz, Frank, van den Hoff, Jörg“…Univariate Cox analysis in the cross-validation and the external testing reveals that manually and automatically derived total MTVs are both highly prognostic with respect to overall survival, yielding essentially identical hazard ratios (HR) ([Formula: see text] ; [Formula: see text] vs. …”
Publicado 2023
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83996por Bafei, Solim Essomandan Clémence, Zhao, Xianghai, Chen, Changying, Sun, Junxiang, Zhuang, Qian, Lu, Xiangfeng, Chen, Yanchun, Gu, Xincheng, Liu, Fangyuan, Mu, Jialing, Wei, Lai, Wei, Pengfei, Yin, Yunjie, Xie, Hankun, Yang, Song, Shen, Chong“…While in the population with increased hs-CRP, only ApoAI > 2.10 g/L had a significant association with CVD [HR (95% CI): 1.69 (1.14–2.51)]. Interaction analyses showed that increased hs-CRP had multiplicative and additive interactions with LDL-C ≥ 160 mg/dL and non-HDL-C ≥ 190 mg/dL on the risk of CVD [HRs (95%CIs): 0.309 (0.153–0.621), and 0.505 (0.295–0.866); RERIs (95%CIs): -1.704 (-3.430-0.021 and − 0.694 (-1.476-0.089), respectively, all P < 0.05]. …”
Publicado 2023
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83997por Witlox, Willem, Grimm, Sabine, Howick, Jeremy, Armstrong, Nigel, Ahmadu, Charlotte, McDermott, Kevin, Otten, Thomas, Noake, Caro, Wolff, Robert, Joore, Manuela“…In the QUAZAR AML-001 trial, oral azacitidine significantly improved overall survival (OS) versus placebo: median OS gain of 9.9 months (24.7 months versus 14.8 months; hazard ratio (HR) 0.69 (95% CI 0.55–0.86), p < 0.001). The median time to relapse was also better for oral azacitidine, and the incidences of TEAEs were similar for the two arms. …”
Publicado 2023
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83998por Derington, Catherine G., Goodrich, Glenn K., Xu, Stanley, Clark, Nathan P., Reynolds, Kristi, An, Jaejin, Witt, Daniel M., Smith, David H., O’Keeffe-Rosetti, Maureen, Lang, Daniel T., Ho, P. Michael, Cheetham, T. Craig, Comer, Angela C., King, Jordan B.“…When directly comparing patients receiving DOAC, the IPTW-adjusted HR was 1.06 (95% CI, 0.85-1.34) for the UC plus PMT group vs the UC group and 0.85 (95% CI, 0.71-1.02) for the AMS group vs the UC group. …”
Publicado 2023
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83999por Bersanelli, Melissa, Verzoni, Elena, Cortellini, Alessio, Giusti, Raffaele, Calvetti, Lorenzo, Ermacora, Paola, Di Napoli, Marilena, Catino, Annamaria, Guadalupi, Valentina, Guaitoli, Giorgia, Scotti, Vieri, Mazzoni, Francesca, Veccia, Antonello, Guglielmini, Pamela Francesca, Perrone, Fabiana, Maruzzo, Marco, Rossi, Ernesto, Casadei, Chiara, Montesarchio, Vincenzo, Grossi, Francesco, Rizzo, Mimma, Travagliato Liboria, Maria Grazia, Mencoboni, Manlio, Zustovich, Fable, Fratino, Lucia, Accettura, Caterina, Cinieri, Saverio, Camerini, Andrea, Sorarù, Mariella, Zucali, Paolo Andrea, Ricciardi, Serena, Russo, Antonio, Negrini, Giorgia, Banzi, Maria Chiara, Lacidogna, Gaetano, Fornarini, Giuseppe, Laera, Letizia, Mucciarini, Claudia, Santoni, Matteo, Mosillo, Claudia, Bonetti, Andrea, Longo, Lucia, Sartori, Donata, Baldini, Editta, Guida, Michele, Iannopollo, Mauro, Bordonaro, Roberto, Morelli, Maria Francesca, Tagliaferri, Pierosandro, Spada, Massimiliano, Ceribelli, Anna, Silva, Rosa Rita, Nolè, Franco, Beretta, Giordano, Giovanis, Petros, Santini, Daniele, Luzi Fedeli, Stefano, Nanni, Oriana, Maiello, Evaristo, Labianca, Roberto, Pinto, Carmine, Clemente, Alberto, Tognetto, Michele, De Giorgi, Ugo, Pignata, Sandro, Di Maio, Massimo, Buti, Sebastiano, Giannarelli, Diana“…The multivariable analyses confirmed the favourable impact of influenza vaccination in terms of OS (HR 0.75, 95% C.I. 0.62–0.92; p = 0.005) and DCR (OR 1.47, 95% C.I. 1.11–1.96; p = 0.007). …”
Publicado 2023
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84000por Wang, Michelle, Slatter, Shadera, Sussell, Jesse, Lin, Chia-Wei, Ogale, Sarika, Datta, Debajyoti, Butte, Atul J., Bazhenova, Lyudmila, Rudrapatna, Vivek A.“…Patients receiving alectinib versus crizotinib as their first ALK TKI treatment experienced significantly prolonged median rwPFS (29.3 versus 10.4 months) with an HR of 0.38 (95% CI 0.21–0.67), while prolonged median mAEFS (not reached versus 91.3 months) and OS (54.1 versus 45.8 months) were observed in patients receiving alectinib versus crizotinib but did not reach statistical significance. …”
Publicado 2023
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