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  1. 84001
    por Weber, Walter P., Matrai, Zoltan, Hayoz, Stefanie, Tausch, Christoph, Henke, Guido, Zimmermann, Frank, Montagna, Giacomo, Fitzal, Florian, Gnant, Michael, Ruhstaller, Thomas, Muenst, Simone, Mueller, Andreas, Lelièvre, Loïc, Heil, Jörg, Knauer, Michael, Egle, Daniel, Sávolt, Ákos, Heidinger, Martin, Kurzeder, Christian, Zwahlen, Daniel R., Gruber, Günther, Ackerknecht, Markus, Kuemmel, Sherko, Bjelic-Radisic, Vesna, Smanykó, Viktor, Vrieling, Conny, Satler, Rok, Hagen, Daniela, Becciolini, Charles, Bucher, Susanne, Simonson, Colin, Fehr, Peter M., Gabriel, Natalie, Maráz, Robert, Sarlos, Dimitri, Dedes, Konstantin J., Leo, Cornelia, Berclaz, Gilles, Fansa, Hisham, Hager, Christopher, Reisenberger, Klaus, Singer, Christian F., Loibl, Sibylle, Winkler, Jelena, Lam, Giang Thanh, Fehr, Mathias K., Kohlik, Magdalena, Clerc, Karine, Ostapenko, Valerijus, Maggi, Nadia, Schulz, Alexandra, Andreozzi, Mariacarla, Goldschmidt, Maite, Saccilotto, Ramon, Markellou, Pagona
    Publicado 2023
    “…In the upfront surgery setting, 296 of 335 patients (88.4%) had hormone receptor (HR)–positive and Erb-B2 receptor tyrosine kinase 2 (ERBB2; formerly HER2 or HER2/neu)–negative disease: 145 (49.0%) underwent ART, and 151 (51.0%) underwent ALND. …”
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    Association of Axillary Dissection With Systemic Therapy in Patients With Clinically Node-Positive Breast Cancer
  2. 84002
    “…Cox proportional-hazards models were constructed and confirmed the independent predictive role of AG in 90-day all-cause mortality risk in SICU after adjusting for 23 confounding factors gradually (HR 1.423, 1.246–1.625, P < 0.001). In the further subgroup analyses, a significant interaction was confirmed between AG and sepsis as well as surgery on the risk for the 90-day mortality. …”
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    Association between anion gap and all-cause mortality of critically ill surgical patients: a retrospective cohort study
  3. 84003
    “…To reduce the risk of hormone receptor positive (HR+) disease recurrence, hormone therapy is prescribed for at least 5 years. …”
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    Impact of web application support versus standard management on adherence with adjuvant hormone therapy in patients treated for breast cancer: the WEBAPPAC study
  4. 84004
    “…Different Techniques such as UV-Vis., XRD, DLS, SEM, EDX, and HR-TEM, were employed for identifying the synthesized NPs. …”
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    Gamma rays-assisted bacterial synthesis of bimetallic silver-selenium nanoparticles: powerful antimicrobial, antibiofilm, antioxidant, and photocatalytic activities
  5. 84005
    “…In addition, a significantly lower proportion of second-line dasatinib patients discontinued their index therapy compared with second-line nilotinib patients (4.4% vs. 8.6%, P = 0.020). With a hazard ratio (HR) of 0.50 (95% CI = 0.27-0.93, P = 0.029), dasatinib patients had half the possibility of discontinuing treatment compared with nilotinib patients at any point in time. …”
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    Adherence and Persistence Among Chronic Myeloid Leukemia Patients During Second-Line Tyrosine Kinase Inhibitor Treatment
  6. 84006
    “…The test result of OncoUrine was also found significantly correlated with recurrence free survival (RFS) of NMIBC patients (median 34.4-month vs unreached; HR 6.0, 95% CI 2.7–13.5, P < 0.0001). CONCLUSIONS: OncoUrine showed potential value to reduce the frequency of unnecessary cystoscopy and the healthcare cost of bladder cancer patients. …”
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    A urinary assay for mutation and methylation biomarkers in the diagnosis and recurrence prediction of non-muscle invasive bladder cancer patients
  7. 84007
    “…Risk of recurrence was significantly reduced in patients treated with TT compared with anti-PD1 (adjusted HR 0.52; 95% CI 0.40 to 0.68, p<0.001). Likewise, median RFS was significantly longer in TT-treated patients (31 vs 17 months, p<0.001). …”
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    Treatment management for BRAF-mutant melanoma patients with tumor recurrence on adjuvant therapy: a multicenter study from the prospective skin cancer registry ADOREG
  8. 84008
    “…In longitudinal analyses the wGRSs for WMH, but not BP or stroke, showed suggestive association with incident all-cause-dementia (HR, 1.02; 95%CI:1.00-1.04; P=.06). BP and stroke wGRSs were strongly associated with mortality but there was no evidence for selective survival bias during follow-up. …”
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    Complexities of cerebral small vessel disease, blood pressure, and dementia relationship: new insights from genetics
  9. 84009
    “…The DSS hazard ratios (HR) for DT <1 year compared to ≥3 years were 8.2 (1.5-45.4) for 2D TVDT, 8.7 (1.6-48.2) for 3D TVDT, 15.9 (1.72-146.7) for Ct-DT, and 11.72 (2.0-68.7) for CEA-DT. …”
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    SAT521 Predictive Value of Tumor Volumetrics in Patients with Medullary Thyroid Cancer
  10. 84010
    “…Women with a combination of high (above median) GLUD1/2+ (>49%) and GPX4+ (>54%) expression had a trend toward decreased survival (Hazard Ratio, HR 3.53, P=0.159). GPX4, GLUD1/2, and estrogen receptor (ER) expression were associated with tumor size in the entire cohort (R(2) = 0.124, P = 0.041), but this relationship was markedly stronger in Black women (R(2) = 0.487, P = 0.040). …”
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    THU495 Glutamate Metabolic Enzymes GLUD1/2 And GPX4 Are Associated with Tumor Size In Black Women With Invasive Lobular Breast Cancer
  11. 84011
    “…Analysis 1 compared fasting insulin, fasting serum uric acid, and FEUA from 24-hr urine collection in 46 patients with LD and 13 with INSR. …”
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    THU268 Hyperuricemia In Insulin Resistance Is Associated With Increased Synthesis And Not Decreased Renal Excretion Of Uric Acid In Humans
  12. 84012
    “…Lab values over the past 10 years are as follows: Ca 8.1-10.6 mg/dl (8.5-10.5), Alb 4.0-4.6 g/dl (3.5-5.4), Phos 4.3-5.5 mg/dl (2.8-4.5), Mg 1.7-1.9 mg/dl (1.3-2.1), K 3.7-4.4 mEq/L (3.6-5.2), Cr 1.0-1.5 mg/dl (0.5-1.3), PTH 0.00-1.4 pg/ml (10-55), 25 OH Vit D 18-58 ng/ml (32-100), 1,25 OH Vit D3 25.5-37.2 pg/ml (19.9-79.3), 24hr Urine Ca 162- 384 mg/24 hrs (50-400). Clinical lessons: Chronic hypoparathyroidism can be well managed with close follow up and frequent lab monitoring. …”
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    SAT224 Nonsurgical Hypoparathyroidism: 40 Years After Diagnosis
  13. 84013
    “…Although the mechanism of disease is not clear, R707 is in the carboxy-terminal coiled-coil domain HR2 of MFN2 and may regulate mitochondrial membrane fusion. …”
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    FRI028 Multiple Symmetric Lipomatosis As A Model For Understanding The Importance Of Mitochondria Function On Adipose Tissue Biology
  14. 84014
    “…At a median follow up of 108 days, 24 (45%) patients treated with adrenalectomy and 16 (80%) patients treated with MRAs demonstrated PRA >1.5 ng/mL/hr, P = 0.008. eGFR decreased by at least 10 points in 15 (30%) patients treated with adrenalectomy vs in 11 (59%) patients treated with MRAs (P=0.033). …”
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    THU568 The Impact of Surgical versus Medical Therapy on Renin Plasma Activity, Renal Function, and Hypertension Control in Patients with Primary Aldosteronism
  15. 84015
    “…Vitals were BP 102/70 mmHg, HR 108 beats/min, RR 18 breaths/min, SpO2 98%, BMI 31.28kg/m(2). …”
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    SAT435 The Quest Of Elevated Dhea-s: Is It A Tumor Or Is It Ashwagandha?
  16. 84016
    “…During each study visit they received either a 2-hour intravenous infusion of kisspeptin-54 at a rate of 1.0 nmol/kg/hr, or a rate-matched vehicle infusion. The study was single-blinded, with participants unaware of the infusion identity. …”
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    FRI007 Kisspeptin Does Not Affect Food Intake In Women With Overweight Or Obesity
  17. 84017
    “…Case report: A 58-year-old woman presented with symptoms of heat intolerance, and unexpected 18-lbs weight loss over 3 months. Physical examination: HR 108 bpm, BP 110/70 mm Hg, normal eye examination, thyroid 45 gms, diffusely enlarged. …”
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    SAT490 Graves’ Disease In Remission Aggravated By Himalayan Salt Consumption
  18. 84018
    “…Positive TT trajectory was associated with shorter survival, after adjustment for SHBG, age, and comorbidities (HR 6.61 [1.46, 29.8], p=0.01). Conclusions: This is one of the first longitudinal studies of the HPT axis in community-dwelling men with longevity. …”
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    OR25-01 Longitudinal Changes in the Hypothalamic-Pituitary-Testicular (HPT) Axis in Men with Longevity
  19. 84019
    “…She presented after initiation of methimazole (MMI) 5 mg twice daily, prescribed by her primary care provider. VS BP 137/70 HR 94 BMI 25.32. Exam-slight tremor on outstretched arms, no ophthalmopathy, 35-40 gm thyromegaly, no onycholysis or pretibial myxedema. …”
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    FRI573 Liver Enzyme Elevation In A Patient With Grave’s Disease; Could This Be Due To Anti-thyroid Drug Therapy?
  20. 84020
    “…Vitals included BP of 144/84 mmhg, RR 20/min, HR 89/min, temp of 98.1°F, and SpO2 of 99%. Physical exam was notable only for RUQ pain and right CVA tenderness. …”
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    FRI229 Bilateral Adrenal Hemorrhage Following Deep Tissue Body Massage
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