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981por Zhang, Yu, Yuan, Bo, Takagi, Norio, Wang, Hongjie, Zhou, Yanyan, Si, Nan, Yang, Jian, Wei, Xiaolu, Zhao, Haiyu, Bian, Baolin“…In this work, 36 and 22 hydrophilic components were characterized from toad skin and venom, respectively, by UHPLC-HR-MS/MS, including amino acids, nucleosides, polypeptides, and indolealkylamines (IAAs). …”
Publicado 2018
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982por Büyükkaramikli, Nasuh C., de Groot, Saskia, Riemsma, Rob, Fayter, Debra, Armstrong, Nigel, Portegijs, Piet, Duffy, Steven, Kleijnen, Jos, Al, Maiwenn J.“…Patient-level data from the BOLERO-2 trial, evaluating the addition of everolimus to exemestane in the second-line treatment of postmenopausal HR-positive advanced breast cancer, were used to inform the length of progression-free survival during the second line. …”
Publicado 2018
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983por Riemslagh, Frederike W., Lans, Hannes, Seelaar, Harro, Severijnen, Lies-Anne W. F. M., Melhem, Shamiram, Vermeulen, Wim, Aronica, Eleonora, Pasterkamp, R. Jeroen, van Swieten, John C., Willemsen, Rob“…Here, we describe HR23B pathology in C9ORF72 linked FTD and amyotrophic lateral sclerosis (ALS) cases. …”
Publicado 2019
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984por Chiarini, Anna, Liu, Daisong, Rassu, Mario, Armato, Ubaldo, Eccher, Claudio, Dal Prà, Ilaria“…High oncogenic risk human papillomaviruses (HR-HPVs) promote cervical carcinoma development, the fourth most common feminine cancer. …”
Publicado 2019
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985por Iwamoto, Naoki, Sato, Shuntaro, Sumiyoshi, Remi, Chiba, Ko, Miyamoto, Nanami, Arinaga, Kumiko, Kobayashi, Makiko, Yamamoto, Hiroshi, Osaki, Makoto, Kawakami, Atsushi“…To analyze bone erosion and bone micro-architecture precisely, high-resolution peripheral quantitative computed tomography (HR-pQCT) will be performed every 6 months. The primary endpoint is changes in the depth of bone erosion as measured by HR-pQCT from baseline to 6 months. …”
Publicado 2019
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986por Pizzuti, Laura, Krasniqi, Eriseld, Barchiesi, Giacomo, Della Giulia, Marina, Izzo, Fiorentino, Sanguineti, Giuseppe, Marchetti, Paolo, Mazzotta, Marco, Giusti, Raffaele, Botticelli, Andrea, Gamucci, Teresa, Natoli, Clara, Grassadonia, Antonino, Tinari, Nicola, Iezzi, Laura, Tomao, Silverio, Tomao, Federica, Tonini, Giuseppe, Santini, Daniele, Astone, Antonio, Michelotti, Andrea, De Angelis, Claudia, Mentuccia, Lucia, Vaccaro, Angela, Magnolfi, Emanuela, Gelibter, Alain, Magri, Valentina, Cortesi, Enrico, D'Onofrio, Loretta, Cassano, Alessandra, Rossi, Ernesto, Cazzaniga, Marina, Moscetti, Luca, Omarini, Claudia, Piacentini, Federico, Fabbri, Maria A., Scinto, Angelo F., Corsi, Domenico, Carbognin, Luisa, Bria, Emilio, La Verde, Nicla, Samaritani, Riccardo, Garufi, Carlo, Barni, Sandro, Mirabelli, Rosanna, Sarmiento, Roberta, Veltri, Enzo M., D'Auria, Giuliana, Paris, Ida, Giotta, Francesco, Lorusso, Vito, Cardillo, Franca, Landucci, Elisabetta, Mauri, Maria, Ficorella, Corrado, Roselli, Mario, Adamo, Vincenzo, Ricciardi, Giuseppina R.R., Russo, Antonio, Berardi, Rossana, Pistelli, Mirco, Fiorio, Elena, Cannita, Katia, Sini, Valentina, D'Ostilio, Nicola, Foglietta, Jennifer, Greco, Filippo, Zamagni, Claudio, Garrone, Ornella, Di Cocco, Barbara, Baldini, Editta, Livi, Lorenzo, Desideri, Isacco, Meattini, Icro, Sarobba, Giuseppina, Del Medico, Pietro, De Tursi, Michele, Generali, Daniele, De Maria, Ruggero, Risi, Emanuela, Ciliberto, Gennaro, Sperduti, Isabella, Villa, Alice, Barba, Maddalena, Di Leo, Angelo, Vici, Patrizia“…There was no PFS2 gain in patients with tumors expressing both hormonal receptors (HRs; p = 0.17), while a trend emerged for tumors with one HR (p = 0.05). Conversely, PFS2 gain was significant in HRs‐negative tumors (p = 0.04). …”
Publicado 2019
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987por Song, Fangbin, Du, Hui, Xiao, Aimin, Wang, Chun, Huang, Xia, Liu, Zhihong, Zhao, Meifang, Men, Hongjian, Wu, Ruifang“…Results: The overall prevalence of hrHPV infection was 11.1%; among them, the highest type was Other hrHPV (8.9%), followed by HPV16 (1.6%) and HPV18 (0.6%). …”
Publicado 2020
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988“…Objective: To explore the distribution of Oncotype DX Breast Recurrence Score (RS), the proportion of receiving chemotherapy, and the relationship between RS and chemotherapy benefit according to detailed age groups in women with hormone receptor-positive, human epidermal growth factor receptor 2-negative, node-negative (HR+/HER2−/N0) breast cancer. Methods: This was an extensive, comprehensive, population-based retrospective study. …”
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989por Nitz, Ulrike, Gluz, Oleg, Kreipe, Hans H., Christgen, Matthias, Kuemmel, Sherko, Baehner, Frederick L., Shak, Steven, Aktas, Bahriye, Braun, Michael, Lüdtke-Heckenkamp, Kerstin, Forstbauer, Helmut, Grischke, Eva-Maria, Nuding, Benno, Darsow, Maren, Schumacher, Claudia, Krauss, Katja, Malter, Wolfram, Thill, Marc, Warm, Mathias, Wuerstlein, Rachel, Kates, Ronald E., Harbeck, Nadia“…CONCLUSIONS: This phase of the WSG-ADAPT HR+/HER2− trial confirms trial design estimates of RS and EPR. …”
Publicado 2020
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990por Booth, Stephen W., Eyre, Toby A., Whittaker, John, Campo, Leticia, Wang, Lai Mun, Soilleux, Elizabeth, Royston, Daniel, Rees, Gabrielle, Kesavan, Murali, Hildyard, Catherine, Kazmi, Farasat, La Thangue, Nick, Kerr, David, Middleton, Mark R., Collins, Graham P.“…METHODS: Patients with advanced solid-organ cancers with high HR23B expression or lymphomas received CXD101 at the recommended phase 2 dose (RP2D). …”
Publicado 2021
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991por Bi, Zhao, Chen, Jia-Jian, Liu, Peng-Chen, Chen, Peng, Wang, Wei-Li, Liu, Yan-Bing, Wang, Chun-Jian, Qiu, Peng-Fei, Lv, Qing, Wu, Jiong, Wang, Yong-Sheng“…BACKGROUND: The genomic tests such as the MammaPrint and Oncotype DX test are being gradually applied for hormone receptor positive/HER-2 negative (HR+/HER2-) breast cancer patients with up to three positive axillary lymph nodes (ALNs). …”
Publicado 2021
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992por Tripathy, Debu, Curteis, Tristan, Hurvitz, Sara, Yardley, Denise, Franke, Fabio, Babu, K. Govind, Wheatley-Price, Paul, Im, Young-Hyuck, Pencheva, Radost, Eddowes, Lucy A., Dionne, Pierre-Alexandre, Chandiwana, David, Pathak, Purnima, Lanoue, Brad, Harbeck, Nadia“…BACKGROUND: The phase III MONALEESA-7 trial (NCT02278120) assessed ribociclib + endocrine therapy (ET) versus ET in premenopausal women with HR+/HER2− advanced breast cancer (ABC). The relationship between work productivity loss (WPL) and domains of European Organisation for Research and Treatment of Cancer Quality of Life (EORTC QLQ-C30) and the breast cancer (BC)-specific module (QLQ-BR23) has not been explored in ABC. …”
Publicado 2022
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993por Chen, Zhi-Wen, Hu, Jian-Fei, Wang, Zu-Wei, Liao, Cheng-Yu, Kang, Feng-Ping, Lin, Cai-Feng, Huang, Yi, Huang, Long, Tian, Yi-Feng, Chen, ShiEnlace del recurso
Publicado 2022
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994“…The present study showcased that RC48 was effective and tolerable for a patient with HR- and HER2-positive BMBC.…”
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995por Salvador Bofill, Javier, Moreno Anton, Fernando, Rodriguez Sanchez, Cesar Augusto, Galve Calvo, Elena, Hernando Melia, Cristina, Ciruelos Gil, Eva Maria, Vidal, Maria, Jiménez-Rodriguez, Begoña, De la Cruz Merino, Luis, Martínez Jañez, Noelia, Villanueva Vazquez, Rafael, de Toro Salas, Ruben, Anton Torres, Antonio, Alvarez Lopez, Isabel Manuela, Gavila Gregori, Joaquin, Quiroga Garcia, Vanesa, Vicente Rubio, Elena, De la Haba-Rodriguez, Juan, Gonzalez-Santiago, Santiago, Diaz Fernandez, Nieves, Barnadas Molins, Agusti, Cantos Sanchez de Ibargüen, Blanca, Delgado Mingorance, Juan Ignacio, Bellet Ezquerra, Meritxell, de Casa, Sonia, Gimeno, Asuncion, Martin, Miguel“…Ribociclib in combination with endocrine therapy (ET) has shown superiority in prolonging survival in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) advanced breast cancer (ABC) vs. …”
Publicado 2022
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996por Bardia, Aditya, Mayer, Ingrid, Winer, Eric, Linden, Hannah M., Ma, Cynthia X., Parker, Barbara A., Bellet, Meritxell, Arteaga, Carlos L., Cheeti, Sravanthi, Gates, Mary, Chang, Ching-Wei, Fredrickson, Jill, Spoerke, Jill M., Moore, Heather M., Giltnane, Jennifer, Friedman, Lori S., Chow Maneval, Edna, Chan, Iris, Jhaveri, KomalEnlace del recurso
Publicado 2022
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997por Avian, Alice, Clemente, Nicolò, Mauro, Elisabetta, Isidoro, Erica, Di Napoli, Michela, Dudine, Sandra, Del Fabro, Anna, Morini, Stefano, Perin, Tiziana, Giudici, Fabiola, Cammisuli, Tamara, Foschi, Nicola, Mocenigo, Marco, Montrone, Michele, Modena, Chiara, Polenghi, Martina, Puzzi, Luca, Tomaic, Vjekoslav, Valenti, Giulio, Sola, Riccardo, Zanolla, Shivani, Vogrig, Enea, Riva, Elisabetta, Angeletti, Silvia, Ciccozzi, Massimo, Castriciano, Santina, Pachetti, Maria, Petti, Matteo, Centonze, Sandro, Gerin, Daniela, Banks, Lawrence, Marini, Bruna, Canzonieri, Vincenzo, Sopracordevole, Francesco, Zanconati, Fabrizio, Ippodrino, RudyEnlace del recurso
Publicado 2023
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