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  1. 3641
    “…The purpose of this paper was to compare the approval dosing regimen among four Asian countries (Korea, Japan, China, and Taiwan) and elucidate the readiness and current status of the implementation of the International Conference on Harmonization (ICH) E17 guidelines on MRCTs. Reducing unnecessary clinical trials via multinational clinical trials in East Asian countries is also suggested. …”
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    The necessary conduct: Exploratory multiregional clinical trials in East Asia
  2. 3642
    “…We underline that harmonization processes are still required for the EQA in the molecular biology field, especially if applied to the evaluation of methods characterized by high complexity.…”
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    Tumor BRCA testing in ovarian cancer and EQA scheme: our experience of a critical evaluation
  3. 3643
    “…Such independent studies are probably from heterogenous populations, which raises several challenges, including: 1) data harmonization (deriving new harmonized variables from differently measured variables by identifying common elements across all studies); 2) systematically missing data (variables not measured are missing for all participants in a cohort); and 3) model selection with differing age ranges and measurement schedules. …”
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    Combining Longitudinal Data From Different Cohorts to Examine the Life-Course Trajectory
  4. 3644
    “…Conclusions: This is the first multinational multidisciplinary survey exploring in detail the opinions and practice on imaging guidance for interventional procedures in RMDs. A harmonization of protocols based on international guidelines, along with adequate training programmes and interventions on barriers at national/local levels are the main unmet needs requiring attention.…”
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    Current Practice of Imaging-Guided Interventional Procedures in Rheumatic and Musculoskeletal Diseases: Results of a Multinational Multidisciplinary Survey
  5. 3645
    “…Discrepancies observed during the processes of translation and harmonization of the back-translations were modified with no need for reformulation. …”
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    Portuguese Translation and Cross-Cultural Adaption of the Banff Patella Instability Instrument
  6. 3646
    “…Recently completed harmonization of 9 loneliness items across three longitudinal twin studies of aging in Sweden resulted in sample of 1939 participants aged 40 to 98 at intake (mean age = 74.64) with up to 25 years of follow-up (mean = 7.63) across up to 8 waves (mean = 3.29). …”
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    Longitudinal Analyses Indicate Bidirectional Associations Between Loneliness and Self-Rated Health in Adulthood
  7. 3647
    por Schwendicke, F., Krois, J.
    Publicado 2021
    “…Concerns and confidence into data-driven applications, stakeholders’ and system’s capabilities, and lack of data standardization and harmonization currently limit the development and implementation of data dentistry. …”
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    Data Dentistry: How Data Are Changing Clinical Care and Research
  8. 3648
    “…These data highlight gaps in prenatal care and issues of health equity that warrant harmonization of obstetrical guidelines to recommend routine ferritin testing in pregnancy.…”
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    Suboptimal iron deficiency screening in pregnancy and the impact of socioeconomic status in a high-resource setting
  9. 3649
    “…The developed and optimized UPLC-DAD methodology was validated according to the guidelines of the International Council for Harmonization (ICH), evaluating the following parameters: range, specificity, linearity (R(2) > 0.999), precision (%RSD < 2%), LOD (0.38–1.01 µg/mL), LOQ (0.54–3.06 µg/mL), and recovery (80–110%). …”
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    Development, Validation, and Application of the UPLC-DAD Methodology for the Evaluation of the Qualitative and Quantitative Composition of Phenolic Compounds in the Fruit of American Cranberry (Vaccinium macrocarpon Aiton)
  10. 3650
    “…Increasing awareness and knowledge of the role and responsibilities of the Principal Investigator (PIs) according to the International Harmonization for Good Clinical Practice (ICH-GCP), Federal Regulations (FDA, DHHS, ect.), and University of Minnesota Policies. …”
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    4507 Developing and implementing a Principal Investigator (PI) primer to improve the conduct of human research at the University of Minnesota
  11. 3651
    “…At the age of day 15, all chickens (except the control group) were administered LC-SPH intramuscularly (chest muscles) at different doses of 20 mg/kg.bw, 60 mg/kg.bw, and 100 mg/kg.bw respectively for 9 consecutive days recommended by veterinary international cooperation on harmonization (VICH) guidelines. The chickens had ad libitum access to antibiotic-free feed and water. …”
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    Safety evaluation study of lincomycin and spectinomycin hydrochloride intramuscular injection in chickens
  12. 3652
    “…Moreover, these effects remained significant after applying recently proposed harmonization algorithms that purport to remove unwanted between‐site variation in diffusion data. …”
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    Widespread effects of dMRI data quality on diffusion measures in children
  13. 3653
    “…The linearity (r(2) > 0.999), precision (<15%), accuracy and recovery (80–120%), limit of detection (5.60 µM and 0.06 µM), limit of quantification (16.98 µM and 0.19 µM), and stability of the newly developed method were validated for dexamethasone and 6β-hydroxydexamethasone, respectively, following International Conference on Harmonization (ICH) guidelines. This method was applied in vitro to measure CYP3A2 activity. …”
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    Development and Validation of a Novel HPLC Method to Analyse Metabolic Reaction Products Catalysed by the CYP3A2 Isoform: In Vitro Inhibition of CYP3A2 Enzyme Activity by Aspirin (Drugs Often Used Together in COVID-19 Treatment)
  14. 3654
    “…Also, why previous attempts to harmonize certain PD-L1 assays were unsuccessful; the assays’ dynamic ranges were too disparate and did not overlap. …”
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    Quantitative comparison of PD-L1 IHC assays against NIST standard reference material 1934
  15. 3655
    por Baldermann, Cornelia
    Publicado 2022
    “…This is not least due to the partly contradictory statements and recommendations regarding the positive and negative health effects, also from the scientific community. A harmonization as well as a collation of the statements and activities of individual players in UV protection related to the prevention of UV-related diseases gives the key messages the necessary strength to make UV protection a matter of course in society. …”
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    UV-Schutz-Bündnis in Deutschland – Zweck und Ziele
  16. 3656
    “…This candidate RMP is fit to assign target values to secondary certified reference materials (CRMs) for further use in external quality assessment schemes to monitor the accuracy and comparability of the commercially available immunoassay results and to confirm the need for improving the harmonization of PCT assays. The candidate RMP will also be used to evaluate whether the correlation between the candidate RMP and immunoassays is sufficiently high. …”
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    Candidate High-Resolution Mass Spectrometry-Based Reference Method for the Quantification of Procalcitonin in Human Serum Using a Characterized Recombinant Protein as a Primary Calibrator
  17. 3657
    “…We derive a strong need for harmonization and quality assurance concerning communication with PALS. …”
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    Talking about the end of life: communication patterns in amyotrophic lateral sclerosis – a scoping review
  18. 3658
    “…Continuous training among laboratories, further criteria and additional clarification of the standards, sharing classifications and supporting evidence through public database, and ongoing work for dosage sensitive genes/regions curation will be beneficial for harmonization of CNVs classification.…”
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    Adaptation of ACMG-ClinGen Technical Standards for Copy Number Variant Interpretation Concordance
  19. 3659
    “…The developed method was validated according to the international conference of harmonization (ICH) guidelines for linearity, detection and quantitation limits, accuracy, precision, specificity, and robustness. …”
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    A stability-indicating HPLC-UV method for the quantification of anthocyanin in Roselle (Hibiscus Sabdariffa L.) spray-dried extract, oral powder, and lozenges()
  20. 3660
    “…Concurrently, we continue the integration and harmonization of infrastructure, processes, and tools with the Alliance of Genome Resources, of which WormBase is a founding member.…”
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    WormBase in 2022—data, processes, and tools for analyzing Caenorhabditis elegans
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