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  1. 4341
    “…We demonstrate that deep learning methods using this representation are capable of accurately predicting multiple medical events from multiple centers without site-specific data harmonization. We validated our approach using de-identified EHR data from two US academic medical centers with 216,221 adult patients hospitalized for at least 24 h. …”
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    Scalable and accurate deep learning with electronic health records
  2. 4342
    “…METHODS: Key regulatory requirements of CTIMS were extracted thorough review of many related regulations and guidelines including International Conference on Harmonization-GCP E6, FDA 21 Code of Federal Regulations parts 11 and 820, Good Automated Manufacturing Practice, and Clinical Data Interchange Standards Consortium. …”
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    A Good Practice–Compliant Clinical Trial Imaging Management System for Multicenter Clinical Trials: Development and Validation Study
  3. 4343
    “…Workshop participants recommended enhanced international harmonization and cooperation and closer collaborations between human and veterinary researchers to expedite progress. …”
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    Non-animal replacement methods for veterinary vaccine potency testing: state of the science and future directions
  4. 4344
    “…Lack of standardization and harmonization of insulin assays limit the clinical use of insulin-based surrogate indexes of insulin resistance. …”
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    SAT-624 Predictive Ability of Lipoprotein Insulin Resistance (LPIR) Score in South Asians: A Comparison of Surrogate Indices of Insulin Sensitivity/Resistance
  5. 4345
    “…However, as discussed in prior studies comparing the performance of common prolactin immunoassays in a reference population of both males and females with and without known hyperprolactinemia or macroprolactinemia, there has been poor harmonization between assays and variable reactivity towards macroprolactin, resulting in significantly different normal ranges for total and monomeric prolactin between manufacturers. …”
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    MON-281 A Pilot Study: Comparing Prolactin Measurements Between Two Different Immunoassays
  6. 4346
    “…BACKGROUND: The European Union (EU) aims to optimize patient protection and efficiency of health-care research by harmonizing procedures across Member States. Nonetheless, further improvements are required to increase multicenter research efficiency. …”
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    How do 66 European institutional review boards approve one protocol for an international prospective observational study on traumatic brain injury? Experiences from the CENTER-TBI study
  7. 4347
    “…INTRODUCTION: Quantitative imaging biomarkers are becoming usual in oncology for assessing therapy response. The harmonization of image quantitation reporting has become of utmost importance due to the multi-center trials increase. …”
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    Evaluation of PET quantitation accuracy among multiple discovery IQ PET/CT systems via NEMA image quality test
  8. 4348
    “…Ghana has deployed DHIMS2 to replace the previously existing manual data harmonization processes. METHODS: This cross-sectional study was conducted in 12 districts comprising 12 district directorates, 10 district hospitals, 29 sub-district health centers, and 38 community health facilities in the Brong-Ahafo Region. …”
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    Utilization of the national cluster of district health information system for health service decision-making at the district, sub-district and community levels in selected districts of the Brong Ahafo region in Ghana
  9. 4349
    “…ABSTRACT: After almost 40 years, the 27 member states (MS) of the European Union (EU) will comply with the European Law 429/2016 in 2021 by completing a process of unification and harmonization of all regulations related to animal health between MS. …”
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    The Implications of EU Regulation 2016/429 on Neglected Diseases of Small Ruminants including Contagious Agalactia with Particular Reference to Italy
  10. 4350
    “…The results of this review may contribute to the development of practice-oriented minimal standards for the governance of data access, which could also result in a stronger harmonization, efficiency, and effectiveness of CDW.…”
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    Implementation of data access and use procedures in clinical data warehouses. A systematic review of literature and publicly available policies
  11. 4351
    “…METHODS: All 124 items in the PRO-CTCAE item library were translated into Dutch using established translation procedures, including dual forward translations, reconciliation, back-translation, reconciliation of the source with the back-translation, and expert reviews. Harmonization of the translation for use in both the Netherlands and Belgium was achieved via an iterative review process in which the translations were discussed and reconciled by consensus of PRO experts, clinicians and bilingual Dutch translators. …”
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    Dutch translation and linguistic validation of the U.S. National Cancer Institute’s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE™)
  12. 4352
    por Hess, Jeremy J., Ranadive, Nikhil, Boyer, Chris, Aleksandrowicz, Lukasz, Anenberg, Susan C., Aunan, Kristin, Belesova, Kristine, Bell, Michelle L., Bickersteth, Sam, Bowen, Kathryn, Burden, Marci, Campbell-Lendrum, Diarmid, Carlton, Elizabeth, Cissé, Guéladio, Cohen, Francois, Dai, Hancheng, Dangour, Alan David, Dasgupta, Purnamita, Frumkin, Howard, Gong, Peng, Gould, Robert J., Haines, Andy, Hales, Simon, Hamilton, Ian, Hasegawa, Tomoko, Hashizume, Masahiro, Honda, Yasushi, Horton, Daniel E., Karambelas, Alexandra, Kim, Ho, Kim, Satbyul Estella, Kinney, Patrick L., Kone, Inza, Knowlton, Kim, Lelieveld, Jos, Limaye, Vijay S., Liu, Qiyong, Madaniyazi, Lina, Martinez, Micaela Elvira, Mauzerall, Denise L., Milner, James, Neville, Tara, Nieuwenhuijsen, Mark, Pachauri, Shonali, Perera, Frederica, Pineo, Helen, Remais, Justin V., Saari, Rebecca K., Sampedro, Jon, Scheelbeek, Pauline, Schwartz, Joel, Shindell, Drew, Shyamsundar, Priya, Taylor, Timothy J., Tonne, Cathryn, Van Vuuren, Detlef, Wang, Can, Watts, Nicholas, West, J. Jason, Wilkinson, Paul, Wood, Stephen A., Woodcock, James, Woodward, Alistair, Xie, Yang, Zhang, Ying, Ebi, Kristie L.
    Publicado 2020
    “…DISCUSSION: This checklist provides guidance for conducting and reporting HEM estimates to make them more comparable and useful for policymakers. Harmonization of HEM estimates has the potential to lead to advances in and improved synthesis of policy-relevant research that can inform evidence-based decision making and practice. https://doi.org/10.1289/EHP6745…”
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    Guidelines for Modeling and Reporting Health Effects of Climate Change Mitigation Actions
  13. 4353
    “…Mechanisms to facilitate improved communication and harmonization among country-specific regulatory bodies are required.…”
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    Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3)
  14. 4354
    “…INTERPRETATION: In the context of FoPL harmonization in Europe, these findings from an online experiment provide insights into the Nutri-Score’s effectiveness on European consumers. …”
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    Objective understanding of the Nutri-score front-of-pack label by European consumers and its effect on food choices: an online experimental study
  15. 4355
    “…Important factors influencing the reforms included, health systems demands for village dispensaries and clinically oriented pharmacists, and harmonization with regional and international training and practice. …”
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    Education of pharmacists in Ghana: evolving curriculum, context and practice in the journey from dispensing certificate to doctor of pharmacy certificate
  16. 4356
    “…Further investigation should be performed to find an appropriate calibration and harmonization protocol and the evaluation should be conducted on a multi-scanner and multi-center level.…”
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    Evaluation of image quality with four positron emitters and three preclinical PET/CT systems
  17. 4357
    “…CONCLUSIONS: With the increase in national BoD studies developing their own strategies in data usage and implementation of statistical methods in the production of BoD estimates, there is a pressing need for equitable capacity building on the one hand, and harmonization of methods on the other hand. In response to these issues, several BoD networks have emerged in the European region that bring together expertise across different domains and professional backgrounds. …”
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    Reflections on key methodological decisions in national burden of disease assessments
  18. 4358
    por Stone, William, Nunes, Abraham, Akiyama, Kazufumi, Akula, Nirmala, Ardau, Raffaella, Aubry, Jean-Michel, Backlund, Lena, Bauer, Michael, Bellivier, Frank, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cruceanu, Cristiana, Dayer, Alexandre, Degenhardt, Franziska, Del Zompo, Maria, Forstner, Andreas J., Frye, Mark, Fullerton, Janice M., Grigoroiu-Serbanescu, Maria, Grof, Paul, Hashimoto, Ryota, Hou, Liping, Jiménez, Esther, Kato, Tadafumi, Kelsoe, John, Kittel-Schneider, Sarah, Kuo, Po-Hsiu, Kusumi, Ichiro, Lavebratt, Catharina, Manchia, Mirko, Martinsson, Lina, Mattheisen, Manuel, McMahon, Francis J., Millischer, Vincent, Mitchell, Philip B., Nöthen, Markus M., O’Donovan, Claire, Ozaki, Norio, Pisanu, Claudia, Reif, Andreas, Rietschel, Marcella, Rouleau, Guy, Rybakowski, Janusz, Schalling, Martin, Schofield, Peter R., Schulze, Thomas G., Severino, Giovanni, Squassina, Alessio, Veeh, Julia, Vieta, Eduard, Trappenberg, Thomas, Alda, Martin
    Publicado 2021
    “…Classification performance could potentially be improved by further harmonization of data collection procedures.…”
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    Prediction of lithium response using genomic data
  19. 4359
    “…Enabling data to be findable, accessible, interoperable, and reusable is currently believed to strengthen data sharing, reduce duplicated efforts, and move toward harmonization of data from heterogeneous unconnected data silos. …”
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    Initiatives, Concepts, and Implementation Practices of FAIR (Findable, Accessible, Interoperable, and Reusable) Data Principles in Health Data Stewardship Practice: Protocol for a Scoping Review
  20. 4360
    “…In use for over 15 years, the nonclinical International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) S7B and clinical ICH E14 guidances describe three core assays (S7B: in vitro hERG current & in vivo QTc studies; E14: thorough QT study) that are used to assess the potential of drugs to cause delayed ventricular repolarization. …”
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    Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective
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