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10361por Froyen, Guy, Le Mercier, Marie, Lierman, Els, Vandepoele, Karl, Nollet, Friedel, Boone, Elke, Van der Meulen, Joni, Jacobs, Koen, Lambin, Suzan, Vander Borght, Sara, Van Valckenborgh, Els, Antoniou, Aline, Hébrant, Aline“…Therefore, the ComPerMed panel of Belgian experts in cancer diagnostics set up a working group with the goal to harmonize the biological classification and clinical interpretation of somatic variants detected by NGS. …”
Publicado 2019
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10362por Shen, Binglin, Yan, Junshuai, Wang, Shiqi, Zhou, Feifan, Zhao, Yihua, Hu, Rui, Qu, Junle, Liu, Liwei“…Results: With such an integrated multi-dimensional system, we searched the metastatic region by two-photon and three-photon excited autofluorescence, analyzed the cancer invasion by second harmonic generation and revealed the affected cellular metabolism by phasor-lifetime. …”
Publicado 2020
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10363por Bergqvist, Christina, Servy, Amandine, Valeyrie-Allanore, Laurence, Ferkal, Salah, Combemale, Patrick, Wolkenstein, Pierre“…Their purpose is to provide health care professionals with guidance regarding the optimal diagnostic and therapeutic management of patients affected with a rare disease; and thus, harmonizing their management nationwide. PNDS are usually developed through a critical literature review and a multidisciplinary expert consensus. …”
Publicado 2020
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10364por Karyolaimos, Alexandros, Dolata, Katarzyna Magdalena, Antelo-Varela, Minia, Mestre Borras, Anna, Elfageih, Rageia, Sievers, Susanne, Becher, Dörte, Riedel, Katharina, de Gier, Jan-Willem“…It is assumed that precisely setting the production rate of a secretory recombinant protein is required to harmonize its production rate with the protein translocation capacity of the cell. …”
Publicado 2020
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10365por Canevelli, Marco, Zaccaria, Valerio, Lacorte, Eleonora, Cova, Ilaria, Remoli, Giulia, Bacigalupo, Ilaria, Cascini, Silvia, Bargagli, Anna Maria, Pomati, Simone, Pantoni, Leonardo, Vanacore, Nicola“…METHODS: The number of MCI cases in older migrants living in Europe and in each of the 32 considered countries was estimated by multiplying the number of migrants, provided by Eurostat, with the age-specific prevalence rates, derived by the harmonized data produced by the COSMIC collaboration and based on different operational definitions of MCI. …”
Publicado 2020
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10366por Alberdi, I., Bender, S., Riedel, T., Avitable, V., Boriaud, O., Bosela, M., Camia, A., Cañellas, I., Castro Rego, F., Fischer, C., Freudenschuß, A., Fridman, J., Gasparini, P., Gschwantner, T., Guerrero, S., Kjartansson, B.T., Kucera, M., Lanz, A., Marin, G., Mubareka, S., Notarangelo, M., Nunes, L., Pesty, B., Pikula, T., Redmond, J., Rizzo, M., Seben, V., Snorrason, A., Tomter, S., Hernández, L.“…The quantification of forests available for wood supply (FAWS) is essential for decision-making with regard to the maintenance and enhancement of forest resources and their contribution to the global carbon cycle. The provision of harmonized forest statistics is necessary for the development of forest associated policies and to support decision-making. …”
Publicado 2020
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10367por Blidner, Richard A., Haynes, Brian C., Hyter, Stephen, Schmitt, Sarah, Pessetto, Ziyan Y., Godwin, Andrew K., Su, Dan, Hurban, Patrick, van Kempen, Léon C., Aguirre, Maria L., Gokul, Shobha, Cardwell, Robyn D., Latham, Gary J.“…The reliable assessment of these RNA markers by next-generation sequencing requires integrated reagents, protocols, and interpretive software that can harmonize procedures and ensure consistent results across laboratories. …”
Publicado 2019
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10368por Zhong, Guoqiang, Ma, Zhuo, Wang, Junbo, Zheng, Chuantao, Zhang, Yu, Wang, Yiding, Tittel, Frank K.“…Assisted by a data acquisition (DAQ) card, a LabVIEW platform was developed to generate the drive signal of the laser and acquire the second harmonic (2f) signal from the output of the detector. …”
Publicado 2020
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10369por Wang, Jiyong, Coillet, Aurelien, Demichel, Olivier, Wang, Zhiqiang, Rego, Davi, Bouhelier, Alexandre, Grelu, Philippe, Cluzel, Benoit“…Interest in metasurfaces operating in the nonlinear regime has also increased due to the ability of metasurfaces to efficiently convert incident light into harmonic frequencies with unusual polarization properties. …”
Publicado 2020
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10370“…Spectral analysis reveals that the power of nonlinear harmonics and the duration of the oscillations increase as the maximum connection strength and the time above threshold increase. …”
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10371“…The best descriptors describing the inhibition mechanism were solvation connectivity index, length to breadth ratio, relative negative charge, harmonic oscillator of aromatic index, average molecular weight and total path count. …”
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10372por McPartland, James C., Bernier, Raphael A., Jeste, Shafali S., Dawson, Geraldine, Nelson, Charles A., Chawarska, Katarzyna, Earl, Rachel, Faja, Susan, Johnson, Scott P., Sikich, Linmarie, Brandt, Cynthia A., Dziura, James D., Rozenblit, Leon, Hellemann, Gerhard, Levin, April R., Murias, Michael, Naples, Adam J., Platt, Michael L., Sabatos-DeVito, Maura, Shic, Frederick, Senturk, Damla, Sugar, Catherine A., Webb, Sara J.“…The study complements published biomarker research through: inclusion of large, deeply phenotyped cohorts of children with ASD and typical development; a longitudinal design; a focus on well-evidenced candidate biomarkers harmonized with an independent sample; high levels of clinical, regulatory, technical, and statistical rigor; adoption of a governance structure incorporating diverse expertise in the ASD biomarker discovery and qualification process; prioritization of open science, including creation of a repository containing biomarker, clinical, and genetic data; and use of economical and scalable technologies that are applicable in developmental populations and those with special needs. …”
Publicado 2020
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10373por Uckermann, Ortrud, Galli, Roberta, Mark, Georg, Meinhardt, Matthias, Koch, Edmund, Schackert, Gabriele, Steiner, Gerald, Kirsch, Matthias“…METHODS: Coherent anti-Stokes Raman scattering (CARS), two-photon excited fluorescence (TPEF), and second-harmonic generation were acquired on cryosections of brain tumors of 382 patients and 28 human nontumor brain samples. …”
Publicado 2020
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10374“…Issued recommendations include reducing daily allowance rates, paying per diem only in exchange for actual work, increasing control mechanisms or harmonizing rates across organizations. In terms of operations, the recommendations call for the implementation of concrete actions to reduce instances of abuse, including not paying advances or introducing reasonable flat-rate per diem. …”
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10375por Bigault, Lionel, Brown, Paul, Bernard, Cécilia, Blanchard, Yannick, Grasland, Béatrice“…This method is the first, validated according a norm for PEDV and may serve as a global reference method to harmonize detection and quantification of PEDV viral RNA in both field and experimental settings.…”
Publicado 2020
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10376por Malyarenko, Dariya I., Newitt, David C., Amouzandeh, Ghoncheh, Wilmes, Lisa J., Tan, Ek T., Marinelli, Luca, Devaraj, Ajit, Peeters, Johannes M., Giri, Shivraman, Vom Endt, Axel, Hylton, Nola M., Partridge, Savannah C., Chenevert, Thomas L.“…The GNL ADC correction based on a previously developed formalism was applied to trace-DWI using system-specific gradient-channel fields derived from vendor-provided spherical harmonic tables. For quantitative DWI phantom images acquired in typical breast imaging positions, the GNC improved interplatform accuracy from a median of 6% down to 0.5% and reproducibility of 11% down to 2.5%. …”
Publicado 2020
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10377por Rouanet, Alice, Bolca, Selin, Bru, Audrey, Claes, Ingmar, Cvejic, Helene, Girgis, Haymen, Harper, Ashton, Lavergne, Sidonie N., Mathys, Sophie, Pane, Marco, Pot, Bruno, Shortt, Colette, Alkema, Wynand, Bezulowsky, Constance, Blanquet-Diot, Stephanie, Chassard, Christophe, Claus, Sandrine P., Hadida, Benjamin, Hemmingsen, Charlotte, Jeune, Cyrille, Lindman, Björn, Midzi, Garikai, Mogna, Luca, Movitz, Charlotta, Nasir, Nail, Oberreither, Manfred, Seegers, Jos F. M. L., Sterkman, Luc, Valo, Audrey, Vieville, Frédérique, Cordaillat-Simmons, Magali“…Even if the pharmaceutical regulatory framework is harmonized at the EU level, obtaining marketing authorisations for medicinal products remains very challenging for Live Biotherapeutic Products (LBPs). …”
Publicado 2020
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10378“…As the bending deformation increases beyond a certain (polymer-specific) point, the change in the convexity properties of the effective bending energy of the polymer makes the harmonic deformation energetically unfavorable: in this strong bending regime the energy of the polymer varies linearly with the average bending angle as the system follows the convex hull of the deformation energy function. …”
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10379por Schlegel, Patrick, Kniesburges, Stefan, Dürr, Stephan, Schützenberger, Anne, Döllinger, Michael“…Regularity of GAW phases and peak shape, harmonic structure and Phonovibrogram-based vocal fold open and closing angles were mainly important. …”
Publicado 2020
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10380por Rockowitz, Shira, LeCompte, Nicholas, Carmack, Mary, Quitadamo, Andrew, Wang, Lily, Park, Meredith, Knight, Devon, Sexton, Emma, Smith, Lacey, Sheidley, Beth, Field, Michael, Holm, Ingrid A., Brownstein, Catherine A., Agrawal, Pankaj B., Kornetsky, Susan, Poduri, Annapurna, Snapper, Scott B., Beggs, Alan H., Yu, Timothy W., Williams, David A., Sliz, Piotr“…While genomic data is frequently collected under distinct research protocols and disparate clinical and research regimes, there is a benefit in streamlining sequencing strategies to create harmonized databases, particularly in the area of pediatric rare disease. …”
Publicado 2020
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