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361“…To test this hypothesis, we knocked down SBP1 expression in HeLa cervical cancer cells by employing a short hairpin RNA (shRNA) approach. …”
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362“…The data described here provide an analysis of the dynamic response of HeLa cell proteome to dithiothreitol (DTT) inducing stress of the endoplasmic reticulum (ER). …”
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363“…In this study, the hexapeptide Phe-Ile-Met-Gly-Pro-Tyr (FIMGPY), which has a molecular weight of 726.9 Da, was separated from skate (Raja porosa) cartilage protein hydrolysate using ultrafiltration and chromatographic methods, and its anticancer activity was evaluated in HeLa cells. Methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay indicated that FIMGPY exhibited high, dose-dependent anti-proliferation activities in HeLa cells with an IC(50) of 4.81 mg/mL. …”
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364por Jafari, Naser, Kim, Hyunju, Park, Rackhyun, Li, Liqing, Jang, Minsu, Morris, Andrew J., Park, Junsoo, Huang, Cai“…We generated NOX4 knockout HeLa cell lines using the CRISPR-Cas9 gene editing system to explore the cellular functions of NOX4. …”
Publicado 2017
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365“…Using single cell analysis in HeLa cells, we show that the CDC20-MAD2 complex is cell cycle regulated with a “Bell” shaped profile and peaks at prometaphase. …”
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366por Gao, Huijun, Sun, Bing, Fu, Hailu, Chi, Xinming, Wang, Faming, Qi, Xiaoyu, Hu, Jun, Shao, Shujuan“…Here, we report that PDIA6 enhances the proliferation of HeLa cells through activation of the Wnt/β-catenin signaling pathway. …”
Publicado 2016
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367“…Depletion of Rad51 caused severe defects in response to postreplicative stress. Accordingly, HeLa cells were arrested at the G2–M transition although a small amount of Rad51 was steadily maintained in HeLa cells. …”
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368por Gorbe, Mónica, Bhat, Ravishankar, Aznar, Elena, Sancenón, Félix, Marcos, M. Dolores, Herraiz, F. Javier, Prohens, Jaime, Venkataraman, Abbaraju, Martínez-Máñez, Ramón“…The calculated IC(50) value was 37.5 µg/mL, similar to others obtained for FAgNPs against HeLa cells.…”
Publicado 2016
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369por El habbash, Aisha I., Mohd Hashim, Najihah, Ibrahim, Mohamed Yousif, Yahayu, Maizatulakmal, Omer, Fatima Abd Elmutaal, Abd Rahman, Mashitoh, Nordin, Noraziah, Lian, Gwendoline Ee Cheng“…Therefore, in this study, α-mangostin (AM) is a plant-derived compound was investigated for the apoptotic effect on human cervical cancer cells (HeLa). The cytotoxic effects of AM on the viability of HeLa and human normal ovarian cell line (SV40) were evaluated by using MTT assay. …”
Publicado 2017
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370por Kumar, Sanjeev, Gomez, Elizabhet Cruz, Chalabi-Dchar, Mounira, Rong, Cong, Das, Sadhan, Ugrinova, Iva, Gaume, Xavier, Monier, Karine, Mongelard, Fabien, Bouvet, Philippe“…Nucleolin is present in the nucleus where it regulates gene expression at the transcriptional and post-transcriptional levels. Using HeLa cells depleted in nucleolin we performed an mRNA and miRNA transcriptomics analysis to identify biological pathways involving nucleolin. …”
Publicado 2017
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371“…These results revealed that Ni NWs induced apoptosis in HeLa cells via ROS generation and cell cycle arrest.…”
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372“…MTS assay and fluorescence micrographs proved that SFH films inhibited the proliferation rate of HeLa cells due to induction of HFE into SF films. …”
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373por Toyoda, Haruka, Mizushima, Tomoe, Satoh, Masahiko, Iizuka, Narushi, Nomoto, Akio, Chiba, Harumi, Mita, Masaharu, Naganuma, Akira, Himeno, Seiichiro, Imura, Nobumasa“…Plasmid pSV2MT‐I encoding mouse metallothionein‐I (MT‐I) designed to be expressed under the control of an SV40 promoter was introduced into human HeLa S3 cells. Several transformants (HeLa/MTH) carrying multi‐copies of mouse MT‐I cDNA in their genomes were isolated. …”
Publicado 2000
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374“…These results suggest that FPOA can induce HeLa cell apoptosis through a caspase-mediated pathway.…”
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375“…EPEC strains adhere to enterocytes and HeLa cells in a characteristic pattern known as localized adherence. …”
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376por Mutlu, Pelin, Yalçin Azarkan, Serap, Taghavi Pourianazar, Negar, Yücel, Meral, Gündüz, Ufuk“…In this study, changes in the expression levels of 186 genes that are thought to be important in drug resistance and Wnt signaling pathways were determined by using qPCR method in doxorubicin-sensitive and -resistant HeLa and K562 cell lines. It has been observed that the genes involved in the Wnt signaling pathways are involved in more changes in HeLa/Dox cells (36 genes) than in the K562/Dox cells (17 genes). …”
Publicado 2018
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377“…[Image: see text] The fluorescence lifetime of the endogenous fluorophore of reduced nicotinamide adenine dinucleotide (NADH) in HeLa cells is affected by the application of nanosecond pulsed electric fields (nsPEFs). …”
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378por Li, Haowen, Li, Yijing, Ao, Hui, Bi, Dongdong, Han, Meihua, Guo, Yifei, Wang, Xiangtao“…Compared to common ACGs nanoparticles (PEG-ACGs-NSps), FA-PEG-ACGs-NSps showed significantly enhanced in vitro cytotoxicity against folate receptor-positive HeLa cell lines (IC50, 0.483 μg/mL vs. 0.915 μg/mL, p < .05), which could be effectively reversed simply by pretreatment of free FA. …”
Publicado 2018
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379por Rebollo-Ramirez, Sonia, Krokowski, Sina, Lobato-Márquez, Damian, Thomson, Michael, Pennisi, Ivana, Mostowy, Serge, Larrouy-Maumus, Gerald“…As a proof of principle, we evaluated the impact of known antibiotics (levofloxacin, ethambutol, and kanamycin) on the lipidome of HeLa cells and mouse bone marrow-derived macrophages. …”
Publicado 2018
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380“…RESULTS: All extracts significantly and concentration dependently reduced viability of HeLa and HepG2 cells. Hexane, chloroform, and butanol extracts at doses of 200, 500, 750, and 1000 μg/ml significantly reduced HeLa cell viability (P < 0.05). …”
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