“…The effects of several sulfonamides on HeLa, MDA-MB-231, HT-29 cancer cell lines, and normal cell lines (HEK-293, PNT-1A) viability were determined. …”
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“…A thin glass cover-slide was mounted on top to monitor the motion of single or aggregated malignant HeLa cells (size 17–30 μm) microscopically through the constricted microchannel at a constant flow rate of 30 μl/h. …”
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“…Fifteen compounds were tested against HeLa cells. Compound 8c was the most active molecule, with an IC(50) value of 13.03 µM, similar to the value of cisplatin (7.37 µM).…”
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“…Here, we describe the synthesis of procyanidin B(1) acetylated analogs and discuss their inhibition activities against HeLa S3 cell proliferation. Surprisingly, the lower-unit acetylated procyanidin B(1) strongly inhibited the proliferation of HeLa S3 cells. …”
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“…In these in vitro experiments, we detected the presence of up to 40-50% apoptotic cell death in HeLa cells and increase in G2-M cell cycle phase from 11%-25% due to treatment with extracellular factors from human breast carcinoma cells. …”
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“…In this study, we established two kinds of Agilent Human lncRNA arrays and examined the effects of heavy ion radiation and X-ray irradiation on HeLa cells. We compared the differences in lncRNA expression (>=2-fold changes) between cells treated with the two types of radiation and control cells and identified 504 lncRNAs and 285 mRNAs that were differentially expressed. …”
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“…Meanwhile, the Nano-PMBE was cytotoxic to HeLa cells (IC(50) of 384.10 µg/ml), caused G0/G1 phase arrest and cell apoptosis in HeLa cells. …”
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“…The anti-proliferative and apoptotic activity of p28 on HeLa and HEK-293 cells were investigated using MTT and PEAnnexin V Flowcytometry assays. …”
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“…In this study, the cytotoxicity of ZnO QDs was assessed using HeLa cervical cancer cell and HEK-293T human embryonic kidney cell lines. …”
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“…Increase in reactive oxygen species formation was observed in the HeLa cells in a time- and dose-dependent manner. …”
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“…We found that persistently infected HeLa cells passaged three times in the presence of 5–10 μM EAV-specific PPMO produced no detectable virus. …”
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“…We validated that time-lapse images of HeLa spheroids provided virtual inner proliferative activity for spheroids in vitro. …”
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“…Here, we evaluated the mechanism of cell death induced by ICRP in HeLa and MCF-7 cells. METHODS: Cell death, cell cycle, mitochondrial membrane potential and ROS production were evaluated in HeLa and MCF-7 cell lines after ICRP treatment. …”
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“…The receptor is found to be biocompatible, as evident by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, and its utility is extended to endogenous and exogenous fluorescence imaging of HeLa cells and zebrafish.…”
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“…Further experimental results suggested that the combination treatment significantly reduced cell viability, invasion and migration of HeLa cells. Overall, the present findings indicated that the low dosage of YM155 sensitized HeLa cells to TRAIL-induced apoptosis via a mechanism involving downregulation of cFLIP and survivin. …”
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“…DISCUSSION AND CONCLUSION: This is the first study reporting cytotoxic activity of WDL in HeLa cells either as single agent or in combination with cisplatin. …”
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“…The assays showed that IC(50) values for Pt in functionalized TiO(2) (NPt) in HeLa (53.74 ± 2.95 μg/mL) and DU-145 (75.07 ± 5.48 μg/mL) were lower than those of pure TiO(2) (74.29 ± 8.95 and 82.02 ± 6.03 μg/mL, respectively). …”
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“…The present work aimed at studying the dual antioxidant/prooxidant behavior of Trolox over a wide range of concentrations (from 2.5 to 160 µM) in HeLa cells. In particular, the study addressed the dose-dependent effects of Trolox on the oxidative cell status and vitality of HeLa cells, focusing on the potential role of the vitamin E analog in the induction of one of the first steps of the apoptotic process, Apoptotic Volume Decrease (AVD). …”
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“…The current study investigated whether hyperoxia may reverse hypoxia-induced radioresistance (RR) in cervical cancer. Human HeLa cells exposed to hypoxic, normoxic or hyperoxic conditions were irradiated using X-rays. …”
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“…Among them, isorhamnetin, chrysoeriol, 2,2′,4′-trihydroxychalcone, and zerumbone enhanced the autophagy flux in HeLa cells. Meanwhile, analysis of the structure–activity relationships indicated that the 3′-methoxy-4′-hydroxy group on the B-ring in the flavone skeleton and an ortho-phenolic group on the chalcone B-ring were crucial for phytochemicals activities. …”
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