“…However, a few hours after the uptake, proteolysis started as indicated by the decreasing red fluorescence intensity in the case of HeLa and MC3T3 cells. 12 h after the uptake, the protein was almost completely degraded in HeLa cells and MC3T3 cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we demonstrated for the first time that 6-S, a novel TrxR inhibitor, promoted oxidative-stress-mediated apoptosis in HeLa cells. The other two constituents of ginger, 6-gingerol (6-G) and 6-dehydrogingerduone (6-DG), have a similar structure to 6-S but fail to kill HeLa cells at low concentrations. 6-Shogaol specifically inhibits purified TrxR1 activity by targeting selenocysteine residues. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, it was investigated how FDPS overexpression (FDPS-OE) regulates the transcriptome in HeLa cells. FDPS-OE increased the proliferation rate in HeLa cells by MTT assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Methods: We transfected HeLa cells with the human Cx46tGFP and characterized the effect of a kanamycin-derived molecule (KI04) on Cx46 hemichannel activity by time-lapse recordings, changes in phosphorylation by Western blot, localization by epifluorescence, and possible binding sites by molecular dynamics (MD). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In view of the tumor‐promoting capacity of prolonged stress, here we investigated (a) the effect of urocortin on cell proliferative signaling via extracellular signal‐regulated kinase 1/2, (b) the expression and cellular distribution of the specific CRF receptor isoforms, and (c) the intracellular localization of phosphorylated ERK1/2 in HeLa cells. Stimulation of cell proliferation was observed in the presence of 10 nm urocortin. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The HeLa cell line was created in 1951 without consent from Henrietta Lacks, the person whose tissue sample was used. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we systematically examine the involvement of FBXO7 in depolarization and (mt)UPR‐dependent mitophagy in the well‐established HeLa and induced‐neurons cell systems. We find that FBXO7(−/−) cells have no demonstrable defect in: (i) kinetics of pUb accumulation, (ii) pUb puncta on mitochondria by super‐resolution imaging, (iii) recruitment of Parkin and autophagy machinery to damaged mitochondria, (iv) mitophagic flux, and (v) mitochondrial clearance as quantified by global proteomics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We reported the ability of polystyrene MNPs to be internalized by HeLa cells could be a reason for the size dependent cytotoxicity of MNPs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: To determine a possible cellular function for TSPY, we manipulated the TSPY expression in HeLa and NIH3T3 cells using the Tet-off system. Cell proliferation, colony formation assays and tumor growth in nude mice were utilized to determine the TSPY effects on cell growth and tumorigenesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…Interferometric and photometric measurements have been made on HeLa cells, a strain of cells originally derived from a human carcinoma. …”
Enlace del recurso
Enlace del recurso

“…A class of RNA in HeLa cytoplasm with a sedimentation value of 22S is described. …”
Enlace del recurso
Enlace del recurso

“…We report here the identification of proteins tightly complexed with poly(A)+ hnRNA in intact HeLa cells, as revealed by a novel in situ RNA- protein cross-linking technique. …”
Enlace del recurso
Enlace del recurso

“…A theoretical model, based on the existence of multiple ER subcompartments of high and low [Ca(2+)], that closely mimics the experimental data obtained in HeLa cells during accumulation of either Ca(2+) or Sr(2+), is presented. …”
Enlace del recurso
Enlace del recurso

“…In the drug-resistant HeLa-C3 cells, flow cytometric analysis revealed a decreased number of apoptotic cells compared with the parental cells. …”
Enlace del recurso
Enlace del recurso

“…When delivered to cultured HeLa pLuc705 cells by Lipofectamine, the PNAs showed dose-dependent nuclear antisense activity in the nanomolar range as inferred from induced luciferase activity as a consequence of pre-mRNA splicing correction by the antisense-PNA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: CK18 negative or positive HeLa cells were invaded equally as well by trypomastigotes of different T. cruzi strains. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The purpose of this study is to elucidate the function of ORAOV1 in cervical cancer cell growth by studying its roles in HeLa cells using small interfering RNA. RESULTS: Functional analyses revealed that ORAOV1 was involved in the regulation of HeLa cell growth through its effect on cell cycle and apoptosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Protein fractions showing nucleolytic activity were tested for cytotoxic activity in human cervical carcinoma HeLa cells. Cultures of HeLa cells were conducted in the presence of three protein concentrations: 42, 83 and 167 ng/ml during 48 h. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso