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441por Lalaoui, Najoua, Morlé, Aymeric, Mérino, Delphine, Jacquemin, Guillaume, Iessi, Elisabetta, Morizot, Alexandre, Shirley, Sarah, Robert, Bruno, Solary, Eric, Garrido, Carmen, Micheau, Olivier“…METHODOLOGY/PRINCIPAL FINDINGS: We provide evidence that TRAIL-R4 can also exhibit, in a ligand independent manner, signaling properties in the cervical carcinoma cell line HeLa, through Akt. Ectopic expression of TRAIL-R4 in HeLa cells induced morphological changes, with cell rounding, loss of adherence and markedly enhanced cell proliferation in vitro and tumor growth in vivo. …”
Publicado 2011
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442por Talman, Virpi, Tuominen, Raimo K., Gennäs, Gustav Boije af, Yli-Kauhaluoma, Jari, Ekokoski, Elina“…In this study we investigated their effects on HeLa human cervical cancer cell viability and proliferation by using standard cytotoxicity tests and an automated imaging platform with machine vision technology. …”
Publicado 2011
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443“…Furthermore, the interaction between frutalin and the HeLa cells was investigated by confocal microscopy. …”
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444por Li, Fen, Ma, Jixian, Ma, Yu, Hu, Yanyan, Tian, Shujuan, White, Richard E., Han, Guichun“…Transfecting antisense plasmid p1107 into HeLa cells highly suppressed hELP3 expression, and substantially reduced expression of HSP70 mRNA and protein. …”
Publicado 2011
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445por Piva, Terrence J., Davern, Catherine M., Hall, Paula M., Winterford, Clay M., Ellem, Kay A. O.“…We have previously shown that in HeLa cells treated with a variety of agents there is an increase in cell surface peptidase (CSP) activity in those cells undergoing apoptosis. …”
Publicado 2012
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446“…Thus, it is suggested that activation of p38 and JNK is a downstream event of AVD for the STS-induced apoptosis of HeLa cells.…”
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447por Wasson, Cassandra J, Zourelias, Jessica L, Aardsma, Nathan A, Eells, Janis T, Ganger, Mike T, Schober, Justine M, Skwor, Troy A“…RESULTS: C. trachomatis-infected HeLa cells were treated with 405 or 670 nm irradiation at varying energy densities (0 – 20 J/cm(2)). …”
Publicado 2012
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448por HUA, YUAN-YUAN, WANG, XIAO-SHU, ZHANG, YU, YAO, CHEN-GUO, ZHANG, XI-MING, XIONG, ZHENG-AI“…MTT assay demonstrated that intense psPEF significantly inhibited the proliferation of HeLa cells in a dose-dependent manner. Typical characteristics of apoptosis in HeLa cells were observed, using transmission electron microscopy. …”
Publicado 2012
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449por Yang, Wei, Tan, Juan, Liu, Ruikang, Cui, Xiaoxu, Ma, Qinglin, Geng, Yunqi, Qiao, Wentao“…Moreover, IRF-1 was recruited to the ISRE site in IFP35 promoter in IFN-γ treated HeLa cells, as demonstrated by electrophoretic mobility shift and chromatin immunoprecipitation assays. …”
Publicado 2012
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450“…Beyond death-inducing properties, we identified the effect of alsterpaullone on cycle procedure and apoptosis of HeLa cell. It was found that alsterpaullone inhibited HeLa cells in a time-dependent (0–72 h) and dose-dependent (0–30 μM) manner. …”
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451por Banko, Monika I., Krzyzanowski, Marek K., Turcza, Paulina, Maniecka, Zuzanna, Kulis, Marta, Kozlowski, Piotr“…When coexpressed with the latter protein, ERH accumulates in replication foci in the nucleus of HeLa cells. Here, we report that when ERH is coexpressed with PDIP46/SKAR in HeLa cells, it is recruited to nuclear speckles, and identify amino acid residues critical for targeting ERH to both these subnuclear structures. …”
Publicado 2013
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452Cytotoxicity of ICD-85 NPs on Human Cervical Carcinoma HeLa Cells through Caspase-8 Mediated Pathwaypor Moradhaseli, Saeed, Zare Mirakabadi, Abbas, Sarzaeem, Ali, Kamalzadeh, Morteza, Haji Hosseini, Reza“…The apoptotic effect of free ICD-85 and ICD-85 NPs on HeLa cells was assessed using caspase-8 colorimetric assay. …”
Publicado 2013
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453por WANG, KEFANG, ZENG, JIANFANG, LUO, LIJING, YANG, JIAXIN, CHEN, JIE, LI, BIN, SHEN, KENG“…The present study aimed to identify the stem cell characteristics of side population (SP) cells sorted from the widely-used HeLa human cervical carcinoma cell line. The SP cells were sorted from the HeLa cell line using fluorescence-activating cell sorting (FACS). …”
Publicado 2013
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454“…METHODS: Cytotoxicity of the algal methanolic extracts (AMEs) on HeLa cells were assayed by 3-(4, 5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide (MTT) reduction assay. …”
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455“…In order to examine bystander effects in the 3D cell system, we have developed a HeLa-FUCCI spheroid system. FUCCI (Fluorescent Ubiquitination-based Cell Cycle Indicator) cells show specific colors of cell nuclei depending on cell cycle. …”
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456“…Using constructs containing a different sized PIR promoter and the luciferase reporter genes we found that in HeLa cells PIR transcription is mostly dependent on a highly conserved antioxidant response element located 281 bp downstream of the transcription start site. …”
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457“…While MG-132 induces HeLa cell death, down-regulation of MCPIP1 expression by siRNA partially protects HeLa cells from MG-132 toxicity and restores Nuclear factor-κB (NF-κB) activity, inhibited by MG-132 treatment. …”
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458por Okamoto, Mayumi, Fujiwara, Mamoru, Hori, Masato, Okada, Kaoru, Yazama, Futoshi, Konishi, Hiroaki, Xiao, Yegui, Qi, Guangying, Shimamoto, Fumio, Ota, Takahide, Temme, Achim, Tatsuka, Masaaki“…Here, we show that combined knockdown of NSUN2 and METTL1 in HeLa cells drastically potentiate sensitivity of cells to 5-fluorouracil (5-FU) whereas heat stress of cells revealed no effects. …”
Publicado 2014
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459por van Bracht, Etienne, Versteegden, Luuk R. M., Stolle, Sarah, Verdurmen, Wouter P. R., Woestenenk, Rob, Raavé, René, Hafmans, Theo, Oosterwijk, Egbert, Brock, Roland, van Kuppevelt, Toin H., Daamen, Willeke F.“…HeLa cells were investigated in more detail using a trypan blue quenching assay, confocal microscopy, and transmission electron microscopy. …”
Publicado 2014
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460por XU, YE, LI, DI, ZENG, LINCHUAN, WANG, CHUNYAN, ZHANG, LILI, WANG, YAN, YU, YANG, LIU, SHIBING, LI, ZHIXIN“…Together, these data indicate that LAC is able to enhance cisplatin cytotoxicity by increasing ER stress-associated apoptosis in HeLa cells.…”
Publicado 2015
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