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  1. 6901
    “…The synthesized AgNPs showed antibacterial activity against the bacterial strains Staphylococcus aureus and Escherichia coli, along with anticancer activity against HeLa cells. After administering nanoparticles to the body, they come in contact with proteins and results in the formation of a protein corona; hence we studied the interactions of these biocompatible AgNPs with hen egg white lysozyme (HEWL) as a carrier protein. …”
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    Biocompatible silver nanoparticles: An investigation into their protein binding efficacies, anti-bacterial effects and cell cytotoxicity studies
  2. 6902
    “…We provided proof of concept by testing five types of cells (HeLa, A549, HepaRG, MCF7 and MCF10A) and determined five biophysical parameters, namely, shear modulus, steady-state viscosity, and relaxation time from the stretching deformation and area-specific membrane capacitance and cytoplasm conductivity from the rotation spectra. …”
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    On-chip integrated optical stretching and electrorotation enabling single-cell biophysical analysis
  3. 6903
    “…A total of 256 differential metabolites were identified in HeLa cells, and 218 differential metabolites were identified in HCT116 cells, respectively. …”
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    Lipidomic profiling reveals lipid regulation by a novel LSD1 inhibitor treatment
  4. 6904
    “…We also used the Caspase-3 biosensor to evaluate the effect of several drugs on the induction of apoptosis of HeLa and MCF-7 tumor cells and inhibition of Zika virus invasion. …”
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    A switch-on molecular biosensor for detection of caspase-3 and imaging of apoptosis of cells
  5. 6905
    “…Functional studies were further conducted in PLAC1-overexpressing HeLa cells and PLAC1-silenced MS751 cells, and western blotting was performed to determine whether PLAC1 promoted CC progression via epithelial-mesenchymal transition (EMT). …”
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    PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer
  6. 6906
    “…We further report that HeLa cells lacking UFL1 have instability of telomeres replicated by leading-strand synthesis. …”
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    UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival
  7. 6907
    “…Additionally, in mitochondria from HeLa, SH-SY5Y, CCL-136 and HepG2 cells, signals for Dp71b and Dp71ab were revealed as well. …”
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    Dystrophin Dp71 Subisoforms Localize to the Mitochondria of Human Cells
  8. 6908
    “…The human cervix adenocarcinoma HeLa cells were treated with Rg3. The protein levels of AMP-activated protein kinase alpha (AMPKα), protein kinase B(Akt), ribosomal S6 protein(S6), and Erk were determined by immunoblotting analyses. …”
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    Ginsenoside Rg3 Promotes Cell Growth Through Activation of mTORC1
  9. 6909
    “…We measured mitophagy in HeLa cells expressing Parkin and in A549, a lung cancer cell line that can undergo mitophagy in a Parkin-independent manner, and we demonstrated that both fluorizoline and rocaglamide A, another PHB-binding molecule, inhibit CCCP- and OA-induced mitophagy. …”
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    The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells
  10. 6910
    “…This compound shows a weak toxicity against HeLa cells (22%) at the minimal active concentration and no hemolytic activity at 100 µg/ml. …”
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    Lichen Polyphenolic Compounds for the Eradication of Candida albicans Biofilms
  11. 6911
    “…In addition, regulating the expression of HPV16 E6 significantly affected the proliferation, apoptosis, migration, and invasion in the cervical cancer HeLa cells, as well as the transcript and protein levels of G6PD. …”
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    HPV16 E6 Promotes the Progression of HPV Infection-Associated Cervical Cancer by Upregulating Glucose-6-Phosphate Dehydrogenase Expression
  12. 6912
    “…Dynamic data of hundreds of HeLa cells treated with TNF-related apoptosis-inducing ligand (TRAIL) were used to characterize the fate-determining kinetic parameters of an apoptosis receptor reaction model. …”
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    Two-level modeling approach to identify the regulatory dynamics capturing drug response heterogeneity in single-cells
  13. 6913
    “…Similarly, 26% proliferation inhibition of HeLa cells was observed with S. asperum extract. …”
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    Antioxidant, Scavenging, Reducing, and Anti-Proliferative Activities of Selected Tropical Brown Seaweeds Confirm the Nutraceutical Potential of Spatoglossum asperum
  14. 6914
    “…However, in vitro assays confirmed that the strain has inhibitory activity on the growth of Candida species and also interferes with their adhesion to HeLa cells. In silico analyses demonstrated a high probability of the protein with antimicrobial activity. …”
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    Genomic Analysis of Limosilactobacillus fermentum ATCC 23271, a Potential Probiotic Strain with Anti-Candida Activity
  15. 6915
    “…Here, several rapid viral metagenomics approaches were tested on simulated next-generation sequencing (NGS) data sets and existing data sets from virus spike-in studies done in CHO-K1 and HeLa cell lines. It was observed that these rapid methods had comparable sensitivity to full-read alignment methods used for NGS viral detection for these data sets, but their specificity could be improved. …”
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    k-mer-Based Metagenomics Tools Provide a Fast and Sensitive Approach for the Detection of Viral Contaminants in Biopharmaceutical and Vaccine Manufacturing Applications Using Next-Generation Sequencing
  16. 6916
    “…These fitness neutral gene perturbations worked as co-therapies in reducing a Salmonella enterica intracellular infection in HeLa. Finally, these results informed the design of four antisense peptide nucleic acid (PNA) co-therapies, csgD, fnr, recA and acrA, against four MDR, clinically isolated bacteria. …”
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    Potentiating antibiotic efficacy via perturbation of non-essential gene expression
  17. 6917
    “…However, no definitive clue about the molecular mechanism linking sorafenib and EGF signalling pathway has been established so far. Our data in HeLa, U2OS, A549 and HEK293T cells, based on in silico, chemical and genetic approaches demonstrate that the MEK5/ERK5 signalling pathway is a novel target of sorafenib. …”
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    ERK5 signalling pathway is a novel target of sorafenib: Implication in EGF biology
  18. 6918
    “…Leader compound 10a showed promising synergy on HeLa cells in conjunction with the TOP1 inhibitor topotecan.…”
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    New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1
  19. 6919
    “…The miRNA expression profile was measured in three models: human adrenocortical adenoma vs. normal tissue, steroid-producing H295R cells and in hormonally inactive HeLa cells before and after dexamethasone treatment. …”
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    Wnt-Signaling Regulated by Glucocorticoid-Induced miRNAs
  20. 6920
    “…Previous studies have shown that fibroblast growth factor 13 (FGF13) is associated with resistance to platinum drugs in HeLa cells. However, the mechanism and universality of this effect have not been clarified. …”
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    FGF13 enhances resistance to platinum drugs by regulating hCTR1 and ATP7A via a microtubule‐stabilizing effect
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