“…Comparison with other essential oils of plants of the same family on anticancer activity against A549, MCF-7, HeLa, and K562, ZOEO showed the highest cytotoxicity with IC(50) of 43.37±6.69, 9.77±1.61, 23.25±7.73, and 60.49±9.41 μg/mL, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Afterward, the hydroxyxanthones were evaluated as antioxidant agents through radical scavenging assay; and anticancer agents through in vitro assays against WiDr, MCF-7, and HeLa cancer cell lines. Hydroxyxanthone 3b was categorized as a strong antioxidant agent (IC(50) = 349 ± 68 µM), while the other compounds were categorized as moderate antioxidant agents (IC(50) > 500 µM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we extended this method to study biology sample through snapshot 3D structure of a single HIV (pseudo-typed with the envelope glycoprotein of vesicular stomatitis virus, VSV-G) at its intermediate stage of viral entry to HeLa cells in a liquid-phase environment. By individual-particle electron tomography (IPET), we found the viral surface release excess lipids with unbound viral spike proteins forming ~50-nm nanoparticles instead of merging cell membrane. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The shoot extract, isolated compounds, and ZnONPs were screened for antibacterial and anticancer effects against four different types of bacterial strains and HeLa cells, respectively. The ZnONPs exhibited the highest zone of inhibition against Escherichia coli and Staphylococcus aureus strains when compared with pure, isolated compounds and shoot extract. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Specifically, we found compound 6 as a new BAG3 modulator with a relevant antiproliferative effect on two different cancer cell lines (IC(50): A375 = 19.36 μM; HeLa = 18.67 μM).…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, in concentrations of 0.5–5 mg/mL the extract inhibited the growth of LoVo, AGS and HeLa cell lines, but was safe for the L929 cells up to the concentration of 5 mg/mL. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MYF5 was significantly downregulated by 69.14% (**p < 0.01) in HeLa cells transfected with mutant MYF5 containing c.191delC compared to those transfected with the wild-type MYF5, resulting in a truncated protein with a size of ∼20 kDa. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We show that accumulation of the secondary messenger bis-(3′,5′)-cyclic dimeric GMP (c-di-GMP) in the pathogenic bacterium Edwardsiella piscicida (E. piscicida) triggers a non-canonical ferroptosis pathway in infected HeLa cells. Moreover, we observed that the dysregulation of c-di-GMP in E. piscicida promotes iron accumulation, mitochondrial dysfunction, and production of reactive oxygen species, all of which that can be blocked by iron chelator. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vitro, Nr‐CWS inhibited the proliferation, colony forming ability of HeLa and SiHa cervical carcinoma cell lines cultured with macrophages, and more cells were blocked in G2/M phase. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Intriguingly, the most relevant features of osmostress-responsive genes are the number of transcription factors targeting them and gene conservation. Using data on HeLa samples, we showed that the same features that define yeast osmostress-responsive genes can predict osmostress-responsive genes in humans, but with changes in the rank-ordering of feature-importance. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results show that silibinin compounds were active on Jurkat, A375, WM266, and HeLa, but at the tested concentrations, they did not interfere with the growth of PANC, MCF-7, HDF or U87. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All compounds were characterized by (1)H-NMR, (13)C-NMR and HRMS, and their anti-tumor activity on various cancer cell lines such as A549, HepG2, HGC-27, MCF-7 and HeLa are also evaluated. From the series of compounds, 9h exhibited the most potent anti-proliferative activity against several cancer cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, DRF-PEG was applied for the ratiometric imaging of Fe(3+) in HeLa cells and showed the potential for quantitative determination of Fe(3+) in fetal bovine serum samples. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, phosphorylation changes the localization of 14-3-3ζ in HeLa and U251 human cancer cells. In summary, our study highlights that phosphomimicking mutations may not faithfully represent the effects of phosphorylation on the protein structure and function and that their use should be justified by comparing to the genuinely phosphorylated counterpart.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Tumor induction in mice with a stably transfected HeLa cell line shows the presence and significant increase in the Sec-miR with time and tumor growth in plasma (p < 0.001, R2 = 0.5542). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vitro analysis was conducted in HeLa cells transiently transfected with plasmids carrying MYO6(W)(T) or MYO6(p.E60Q), and a zebrafish model was generated to characterize the in vivo phenotype. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Cignal Finder Reporter Array evaluated [pathways affected by the splice modulators in HeLa cells. Further, the candidates associated with the pathways were validated at protein level using western blot assay, and gene-gene interaction studies were carried out using GeneMANIA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We next analysed the co-localisation of CNN and the commercial lysosomal probe LTG in cells, qualitatively analysed the imaging characteristics of CNN in different cells (i.e. H9C2, HeLa and HepG2 cells) via structured illumination microscopy and observed how CNN entered cells at different temperatures and levels of endocytosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RNA-fluorescence in situ hybridization confirmed the location of circCDK6 and miR-449a in HeLa and CaSki cells, respectively. Then, the biological function of silencing circCDK6 in cellular proliferation, metastasis, and Epithelial-Mesenchymal Transition (EMT)-related process was determined. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cytotoxicity experiments on HeLa cells revealed that both chitosan and chitosan-coated magnesium cobalt ferrite nanoparticles are biocompatible. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso