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7661“…In vitro study, the SiHa and HeLa cell biologically including cell proliferation, migration, and invasion of si‐FEZF1‐AS1 group which knockdown lncRNA FEZF1‐AS1 were significantly depressed (p < .001, respectively). …”
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7662por Arjona, María Isabel, González-Manchón, Consuelo, Durán, Sara, Duch, Marta, del Real, Rafael P., Kadambi, Abhinav, Agusil, Juan Pablo, Redondo-Horcajo, Mariano, Pérez-García, Lluïsa, Gómez, Elvira, Suárez, Teresa, Plaza, José Antonio“…Devices were found to be internalized by HeLa cells without interfering in their viability. …”
Publicado 2021
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7663por Siddiqui, Arafat, Tumiati, Manuela, Joko, Alia, Sandholm, Jouko, Roering, Pia, Aakko, Sofia, Vainionpää, Reetta, Kaipio, Katja, Huhtinen, Kaisa, Kauppi, Liisa, Tuomela, Johanna, Hietanen, Sakari“…We show that the percentage of HR and NHEJ efficient HeLa cells decreased more than 50% by combining c-Abl inhibitor imatinib with mitoxantrone. …”
Publicado 2021
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7664“…In vitro and in vivo experiments demonstrated that knockdown of IPO7 inhibited the proliferation of HeLa and C-4 I cells. LC-MS/MS analysis showed that IPO7-related cargo proteins mainly were enriched in gene transcription regulation. …”
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7665por Rodríguez-Valverde, Diana, León-Montes, Nancy, Soria-Bustos, Jorge, Martínez-Cruz, Jessica, González-Ugalde, Ricardo, Rivera-Gutiérrez, Sandra, González-y-Merchand, Jorge A., Rosales-Reyes, Roberto, García-Morales, Lázaro, Hirakawa, Hidetada, Fox, James G., Girón, Jorge A., De la Cruz, Miguel A., Ares, Miguel A.“…In summary, we found that CRP directly activates the transcription of the aroX and NRPS operons and that the absence of CRP reduced cytotoxicity of K. oxytoca on HeLa cells, due to a significant reduction in TV production. …”
Publicado 2021
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7666por Gellrich, Antonin, Scharfenberg, Franka, Peters, Florian, Sammel, Martin, Helm, Ole, Armbrust, Fred, Schmidt, Frederike, Lokau, Juliane, Garbers, Christoph, Sebens, Susanne, Arnold, Philipp, Becker-Pauly, Christoph“…Furthermore, employing an assay for cell migration in a collagen IV matrix, we observed that the transfection of wild-type meprin β and the G45R variant resulted in increased migration of HeLa cells, while the G89R variant led to diminished mobility.…”
Publicado 2021
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7667por Dhanalekshmi, K. I., Magesan, P., Umapathy, M. J., Zhang, Xiang, Srinivasan, N., Jayamoorthy, K.“…Additionally, the cell viability of the synthesized nanocomposites was carried out in HeLa cell lines under different concentrations, light doses and incubation periods using an LED light source. …”
Publicado 2021
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7668por Wangsawat, Niwana, Nahar, Lutfun, Sarker, Satyajit D., Phosri, Cherdchai, Evans, Andrew R., Whalley, Anthony J. S., Choowongkomon, Kiattawee, Suwannasai, Nuttika“…Cytotoxicity was recorded against A549, HepG2, HeLa and PNT2 and resulted in broad spectrum to specific activity depending on the cell lines. …”
Publicado 2021
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7669por Liu, Ying, Yu, Shiting, Xing, Xin, Qiao, Juhui, Yin, Yiqiu, Wang, Jiawen, Liu, Meichen, Zhang, Wei“…Previously, we reported that G-Rh2 induces apoptosis in HeLa cervical cancer cells and that the process was related to reactive oxygen species (ROS) accumulation and mitochondrial dysfunction. …”
Publicado 2021
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7670por Furutani, Yutaka, Toguchi, Mariko, Higuchi, Shoko, Yanaka, Kaori, Gailhouste, Luc, Qin, Xian-Yang, Masaki, Takahiro, Ochi, Sae, Matsuura, Tomokazu“…IFN-α and CDM-3008 suppressed SARS-CoV-2 subreplicon RNA in a dose-dependent manner, with IC50 values of 193 IU/mL and 2.54 μM, respectively. HeLa cells stably expressing SARS-CoV-2 subreplicon RNA were prepared and treated with the IFN-α and pan-JAK inhibitor Pyridone 6 or siRNA-targeting ISG20. …”
Publicado 2021
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7671por Zhou, Jinhan, Tan, Yuping, Zhang, Yuqing, Tong, Aiping, Shen, Xiaofei, Sun, Xiaodong, Jia, Da, Sun, Qingxiang“…Further, several Ran cancer mutants were compromised in autoinhibition, slightly more GTP-bound, more cytoplasmic, and enhanced the proliferation of A549 and HeLa cells in vitro. Thus, our work reveals a new route of Ran activation independent of guanine nucleotide exchange factor (GEF), which may account for the hyper-proliferation induced by Ran cancer mutations.…”
Publicado 2020
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7672por Paradkar, P.H., Juvekar, A.S., Barkume, M.S., Amonkar, A.J., Joshi, J.V., Soman, G., Vaidya, A.D.B.“…METHODS AND MATERIALS: In vitro cytotoxicity of this formulation was assessed at 10, 20, 40, and 80 μg/ml concentrations, in three cervical cancer cell lines (HeLa, SiHa, ME180) using Sulforhodamine B assay. …”
Publicado 2021
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7673por Peng, Guangnan, Gu, Ao, Niu, Hongyan, Chen, Linlin, Chen, Yan, Zhou, Miaojin, Zhang, Yiti, Liu, Jie, Cai, Licong, Liang, Desheng, Liu, Xionghao, Liu, Mujun“…METHODS: In this study, we transfected UBQLN2‐WT or UBQLN2‐P497H plasmids into cell lines (HEK293T, HeLa), and observed the process of SG dynamics by immunofluorescence. …”
Publicado 2021
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7674por Wei, Simin, Wang, Yinghui, Tang, Zhishu, Xu, Hongbo, Wang, Zhe, Yang, Tian, Zou, Taiyan“…The IC(50) for HCT116, HepG2 and HeLa cell lines were 13.07, 19.67, and 26.18 μg mL(−1), respectively. …”
Publicado 2021
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7675por Arora, Rohit, Van Theemsche, Kenny M., Van Remoortel, Samuel, Snyders, Dirk J., Labro, Alain J., Timmermans, Jean-Pierre“…By stimulating human MRGPRD-expressing HeLa cells with the agonist β-alanine, we observed a release of IL-6. β-alanine-induced signaling through MRGPRD was investigated further by probing downstream signaling effectors along the Gαq/Phospholipase C (PLC) pathway, which results in an IkB kinases (IKK)-mediated canonical activation of nuclear factor kappa-B (NF-κB) and stimulation of IL-6 release. …”
Publicado 2021
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7676por Grinchenko, Andrei V., von Kriegsheim, Alex, Shved, Nikita A., Egorova, Anna E., Ilyaskina, Diana V., Karp, Tatiana D., Goncharov, Nikolay V., Petrova, Irina Y., Kumeiko, Vadim V.“…Intriguingly, MkC1qDC was found to suppress proliferation of human adenocarcinoma HeLa cells in a dose-dependent manner, indicating to the biomedical potential of MkC1qDC protein.…”
Publicado 2021
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7677por Kamada, Takafumi, Otomo, Kohei, Murata, Takashi, Nakata, Kaito, Hiruma, Shota, Uehara, Ryota, Hasebe, Mitsuyasu, Nemoto, Tomomi“…As a proof of concept, we performed multi-color fluorescent imaging of actively dividing human HeLa cells and tobacco BY-2 cells. We found that the proposed microscopy system enabled time-lapse multi-color 3D imaging of cell divisions while avoiding photodamage. …”
Publicado 2022
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7678por Gordhandas, Sushmita B., Manning-Geist, Beryl, Henson, Christina, Iyer, Gopa, Gardner, Ginger J., Sonoda, Yukio, Moore, Kathleen N., Aghajanian, Carol, Chui, M. Herman, Grisham, Rachel N.“…Athymic nude female mice with established tumors derived from HeLa cells injected into the flank were treated with vehicle alone (n = 3), IR alone (n = 4), and peposertib (M38814) in combination with IR (M3814 + IR; n = 4). …”
Publicado 2022
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7679por Mao, Xiaoman, Wu, Shuang, Calero-Pérez, Pilar, Candiota, Ana P., Alfonso, Paula, Bruna, Jordi, Yuste, Victor J., Lorenzo, Julia, Novio, Fernando, Ruiz-Molina, Daniel“…This complex considerably augmented solubility in contrast to cisplatin and showed a comparable cytotoxic effect on cisplatin in HeLa, 1Br3G and GL261 cells. Furthermore, preclinical in vivo therapy using the intranasal administration route suggested that it can reach the brain and inhibit the growth of orthotopic GL261 glioblastoma. …”
Publicado 2022
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7680por Peng, Liang, Gao, Jingping, Hu, Zihao, Zhang, Hongbo, Tang, Lingli, Wang, Fuyan, Cui, Lei, Liu, Shanshan, Zhao, Yujie, Xu, Hong, Su, Xin, Feng, Xiaojing, Fang, Yiyuan, Chen, Jianlin“…To delineate interactions between C5 and chlamydial infection, cleavage products in a co-incubation system containing purified human C5 and C. trachomatis-HeLa229 cell lysates were analyzed, and a novel cleavage pattern of C5 activation induced by C. trachomatis infection was identified. …”
Publicado 2022
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