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7901por Galindo-Moreno, J, Iurlaro, R, El Mjiyad, N, Díez-Pérez, J, Gabaldón, T, Muñoz-Pinedo, C“…However, knocking down its expression in HeLa cells did not regulate cell death induced by interferon-gamma. …”
Publicado 2014
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7902por Santa Cruz, Ana, Meşe, Gülistan, Valiuniene, Laima, Brink, Peter R., White, Thomas W., Valiunas, Virginijus“…We determined the biophysical properties of these mutant gap junctions in transiently transfected HeLa and N2A cells. All three mutants showed macroscopic junctional conductances over the range of 0.5 to 40 nS, and voltage dependences comparable to those of wild-type (WT) Cx40. …”
Publicado 2015
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7903por Fernández Larrosa, P N, Ruíz Grecco, M, Mengual Gómez, D, Alvarado, C V, Panelo, L C, Rubio, M F, Alonso, D F, Gómez, D E, Costas, M A“…Furthermore, we found that RAC3 overexpression is required in order to maintain the telomerase activity. In tumoral HeLa cells its activity was inhibited by depletion of RAC3 inducing replicative senescence. …”
Publicado 2015
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7904por Xi, Linghe, Schmidt, Jens C., Zaug, Arthur J., Ascarrunz, Dante R., Cech, Thomas R.“…TERT co-localizes detectably with only 5–7 % of the telomeres at a time in S-phase HeLa cells; no nucleolar localization is detected. …”
Publicado 2015
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7905“…The effect was confirmed in HeLa and U2OS cancer cell lines using two independent siRNAs, and in mouse embryonic stem (ES) cells with inducible deletion of Brca1. …”
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7906“…Here we report a novel pathway by which DRAM1 regulates apoptosis involving BAX and lysosomes. A549 or HeLa cells were treated with the mitochondrial complex II inhibitor, 3-nitropropionic acid (3NP), or an anticancer drug, doxorubicin. …”
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7907“…Intriguingly, the UV-induced damage responses via HAUSP-ANXA1 interaction in HeLa cells were different from the responses shown in the Jurkat cells, suggesting that their change of roles may depend on the cell types.…”
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7908“…Interestingly, VTRNA2-1-5p inhibition also increased cisplatin-induced apoptosis of HeLa and SiHa cells. In human clinical cervical cancer specimens, low p53 expression and high VTRNA2-1-5p expression were positively associated. …”
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7909por Esmaeeli-Nieh, Sahar, Fenckova, Michaela, Porter, Iain M., Motazacker, M. Mahdi, Nijhof, Bonnie, Castells-Nobau, Anna, Asztalos, Zoltan, Weißmann, Robert, Behjati, Farkhondeh, Tzschach, Andreas, Felbor, Ute, Scherthan, Harry, Sayfati, Seyed Morteza, Ropers, H. Hilger., Kahrizi, Kimia, Najmabadi, Hossein, Swedlow, Jason R., Schenck, Annette, Kuss, Andreas W.“…However, in contrast to the mitotic arrest observed in BOD1-siRNA treated HeLa cells, patient-derived cells progressed through mitosis with no apparent segregation defects but at an accelerated rate compared to controls. …”
Publicado 2016
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7910por Zhao, Jun-Wei, Li, Hai-Lou, Ma, Xing, Xie, Zhigang, Chen, Li-Juan, Zhu, Yongsheng“…Moreover, the cytotoxicity tests of 4 and 8 toward human cervical cancer (HeLa) cells, human breast cancer (MCF–7) cells and mouse fibroblast (L929) cells were performed by the 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay and the cell apoptosis processes were characterized by calcein AM/PI staining experiments, annexin V-FITC/PI staining experiments and morphological changes.…”
Publicado 2016
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7911por Delay, Charlotte, Grenier-Boley, Benjamin, Amouyel, Philippe, Dumont, Julie, Lambert, Jean-Charles“…METHODS: Stringent in silico analyses were developed to select potential polymorphisms susceptible to impairment of miRNA-mediated repression, and subsequent functional assays were performed in HeLa and HEK293 cells. RESULTS: Two polymorphisms were identified and further analyzed in vitro. …”
Publicado 2016
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7912por Nakamura, Teruko, Furukawa, Asuka, Uchida, Keisuke, Ogawa, Tomohisa, Tamura, Tomoki, Sakonishi, Daisuke, Wada, Yuriko, Suzuki, Yoshimi, Ishige, Yuki, Minami, Junko, Akashi, Takumi, Eishi, Yoshinobu“…METHODS: Three cell lines from macrophages (Raw264.7), mesenchymal cells (MEF), and epithelial cells (HeLa) were infected by viable or heat-killed P. acnes (clinical isolate from sarcoid lymph node) at a multiplicity of infection (MOI) of 100 or 1000 for 1 h. …”
Publicado 2016
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7913por El-Gamal, Ali A., Al-Massarani, Shaza M., Shaala, Lamiaa A., Alahdald, Abdulrahman M., Al-Said, Mansour S., Ashour, Abdelkader E., Kumar, Ashok, Abdel-Kader, Maged S., Abdel-Mageed, Wael M., Youssef, Diaa T. A.“…The total alcoholic and n-hexane extracts showed remarkable cytotoxic activity against human cervical cancer (HeLa), human hepatocellular carcinoma (HepG-2), and human medulloblastoma (Daoy) cancer cell lines. …”
Publicado 2016
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7914por Huh, M S, Ivanochko, D, Hashem, L E, Curtin, M, Delorme, M, Goodall, E, Yan, K, Picketts, D J“…Moreover, DNA damage, induced Parp-1 and Atm activation is elevated in progenitor cells and contributes to their increased level of cell death. ATRX-null HeLa cells are similarly sensitive to hydroxyurea-induced replication stress, accumulate DNA damage and proliferate poorly. …”
Publicado 2016
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7915por Li, Sheng, Yang, Li-juan, Wang, Ping, He, Yu-jiao, Huang, Jun-mei, Liu, Han-wei, Shen, Xiao-fei, Wang, Fei“…Apigenin also sensitized the inhibitory effect of IFN-α on viability of cervical carcinoma HeLa cells. CONCLUSION: These results suggest that apigenin potentiates the inhibitory effect of IFN-α on cancer cell viability by activating JAK/STAT signaling pathway through inhibition of 26S proteasome-mediated IFNAR1 degradation. …”
Publicado 2016
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7916por An, Ha-Rim, Park, So Young, Kim, Hyeran, Lee, Che Yoon, Choi, Saehae, Lee, Soon Chang, Seo, Soonjoo, Park, Edmond Changkyun, Oh, You-Kwan, Song, Chan-Geun, Won, Jonghan, Kim, Youn Jung, Lee, Jouhahn, Lee, Hyun Uk, Lee, Young-Chul“…Such well-purified water (>90%) can utilize culturing of cervical cancer cells (HeLa), breast cancer cells (MCF-7), and keratinocyte cells (HaCaT) while showing minimal cytotoxicity. …”
Publicado 2016
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7917por Shi, Xiaofeng, Liu, Dongyan, Zhang, Junmin, Hu, Pengbin, Shen, Wei, Fan, Bin, Ma, Quhuan, Wang, Xindi“…By comparison, TFPNCD inhibited the proliferation to a less extent in human cervical carcinoma HeLa, gastric cancer MKN28 cells, glioma SHG-44 cells and lung carcinoma A549 than HepG2 cells. …”
Publicado 2016
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7918por Clemente, Tatiana Mordente, Cortez, Cristian, Novaes, Antônio da Silva, Yoshida, Nobuko“…CM of highly invasive CL strain (CL-CM) contained gp90 and gp82 at very low levels. HeLa cells were incubated for 1 h with CL strain MT in D10, in absence or in the presence of G-CM or CL-CM. …”
Publicado 2016
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7919por Morley, Valerie J., Sistrom, Mark, Usme-Ciro, Jose A., Remold, Susanna K., Turner, Paul E.“…We allowed vesicular stomatitis virus (VSV) lineages to evolve in replicated environments containing BHK-21 (baby hamster kidney) cells, HeLa (human epithelial) cells, or spatially heterogeneous host cell mixtures. …”
Publicado 2016
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7920por Mazzari, Andre L. D. A., Milton, Flora, Frangos, Samantha, Carvalho, Ana C. B., Silveira, Dâmaris, de Assis Rocha Neves, Francisco, Prieto, Jose M.“…Their mechanisms of action were further studied by measuring the activation of human pregnane X receptor (hPXR) in transiently co-transfected HeLa cells and the inhibition of γ-glutamyl transferase (GGT) in HepG2 cells. …”
Publicado 2016
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