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8281por Kumnerdkhonkaen, Piyawan, Saenglee, Somprasong, Asgar, Md. Ali, Senawong, Gulsiri, Khongsukwiwat, Kanoknan, Senawong, Thanaset“…METHODS: Anticancer activity of the extracts was evaluated against HeLa, HT29, HCT116, MCF7 and Jurkat cells using an MTT assay and flow cytometric analysis of apoptosis induction and cell cycle arrest. …”
Publicado 2018
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8282Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancerspor Ogura, Yukiko, Hoshino, Tyuji, Tanaka, Nobuko, Ailiken, Guzhanuer, Kobayashi, Sohei, Kitamura, Kouichi, Rahmutulla, Bahityar, Kano, Masayuki, Murakami, Kentarou, Akutsu, Yasunori, Nomura, Fumio, Itoga, Sakae, Matsubara, Hisahiro, Matsushita, Kazuyuki“…Further, anticancer drugs (cis-diaminedichloroplatinum/cisplatin [CDDP] or 5-fluorouracil [5-FU]) and knockdown of FIR by small interfering RNA (siRNA) increased cyclin E while knockdown of FIRΔexon2 by siRNA decreased cyclin E expression in ESCC cell lines (TE1, TE2, and T.Tn) or cervical SCC cells (HeLa cells). Especially, knockdown of SAP155 (SF3b1), a splicing factor required for proper alternative splicing of FIR pre-mRNA, decreased cyclin E. …”
Publicado 2018
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8283“…Here, we report that NF-κB p65 nuclear accumulation and NF-κB-dependent transcription are inhibited in O. tsutsugamushi infected HeLa cells and/or primary macrophages, even in the presence of TNFα. …”
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8284por Netsch, P., Elvers-Hornung, S., Uhlig, S., Klüter, H., Huck, V., Kirschhöfer, F., Brenner-Weiß, G., Janetzko, K., Solz, H., Wuchter, P., Bugert, P., Bieback, K.“…MSCs from bone marrow (BM), lipoaspirate (LA) and cord blood (CB) were compared to human umbilical vein endothelial cells or HeLa tumor cells as inhibitory or activating cells, respectively. …”
Publicado 2018
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8285por Bundale, Sunita, Singh, Jaya, Begde, Deovrat, Nashikkar, Nandita, Upadhyay, Avinash“…The peptide extract of isolate KCR3 and a polyketide extract of isolate NCD10 were found to possess anti-tumor activity exhibiting an IC(50) value of 3 μg/ml and 2.5 μg/ml against HeLa cells.…”
Publicado 2018
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8286“…Shh signaling and cilia structure was studied using two different cell lines, mouse NIH3T3 and human HeLa cells. To investigate how Aβ levels affect Shh signaling and cilia structure in these cells, we utilized naturally secreted Aβ as well as synthetic Aβ. …”
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8287por Lopez-Charcas, Osbaldo, Espinosa, Ana Maria, Alfaro, Ana, Herrera-Carrillo, Zazil, Ramirez-Cordero, Belen Ernestina, Cortes-Reynosa, Pedro, Perez Salazar, Eduardo, Berumen, Jaime, Gomora, Juan Carlos“…Additionally, we found that CeCa cell lines, C33A, SiHa, CaSki and HeLa, express mainly the splice variant of SCN8A that lacks exon 18, shown to encode for an intracellularly localized Na(V)1.6 channel, whereas the full-length adult form was present in CeCa biopsies. …”
Publicado 2018
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8288“…The efficacy of SN-38lip was assessed by in vitro studies with two tumor cell lines (HeLa and Caco-2) and compared with that of SN-38sol. …”
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8289por Sutou, Shizuyo, Koeda, Akiko, Komatsu, Kana, Shiragiku, Toshiyuki, Seki, Hiroshi, Yamakage, Kohji, Niitsuma, Takeru, Kudo, Toshiyuki, Wakata, Akihiro“…Before examination of thresholds in chemical mutagenesis, hormetic responses in cytotoxicity were tested using cultured mammalian cells. METHOD: Human cells (HeLa S3 and TK6) or Chinese hamster cells (CHL/IU) were cultured in 96-well plates and treated with mitomycin C (MMC) or ethyl methanesulfonate (EMS) at various dose levels and optical density was measured after addition of a reagent to detect cellular activity. …”
Publicado 2018
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8290por Elbashir, Sara Mustafa Idris, Devkota, Hari Prasad, Wada, Mikiyo, Kishimoto, Naoki, Moriuchi, Masataka, Shuto, Tsuyoshi, Misumi, Shogo, Kai, Hirofumi, Watanabe, Takashi“…Furthermore, the active plant extracts were investigated for their cytotoxicity and genotoxicity on HeLa cell line using HCS DNA Damage Assay. RESULTS: Both 70% ethanol and water extracts of Acacia nilotica, Ziziphus spina-christi, Abrus precatorius, and Geigeria alata along with the 70% ethanol extract of Martynia annua showed potent free radical scavenging activity. …”
Publicado 2018
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8291“…Three human CC cell lines (HeLa, C33A and SiHa) and a normal cervical cell line Crl-2614 and were transfected with human ZEB1-AS1 cDNA, or empty vector as the control. …”
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8292por Carden, Sarah, van der Watt, Pauline, Chi, Alicia, Ajayi-Smith, Aderonke, Hadley, Katie, Leaner, Virna D.“…Additionally, Kpnβ1 overexpressing HeLa cells exhibited increased sensitivity to cisplatin, as shown by decreased cell viability and increased apoptosis, where p53 and p21 inhibition reduced and enhanced cell sensitivity to Cisplatin, respectively. …”
Publicado 2018
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8293“…This interaction was dependent on the concentration of C2 toxin and detected in mammalian Vero and human HeLa cells. Moreover, the present study reveals that combination of radicicol, VER-155008, cyclosporine A, and FK506, which are specific pharmacological inhibitors of Hsp90, Hsp70, Cyps, and FKBPs, respectively, resulted in a stronger inhibition of intoxication of cells with C2 toxin compared to application of the single inhibitors. …”
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8294por Zhang, Li, Zhu, Xiaoyu, Wu, Shijia, Chen, Yazhou, Tan, Shiming, Liu, Yingjie, Jiang, Wenzheng, Huang, Jing“…The tumor suppression activity and drug distribution was analyzed in nude mice bearing with HeLa tumor cells. RESULTS: The nano-size was 110±28 nm detected with TEM and 89±18 nm detected with DLS, respectively. …”
Publicado 2018
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8295por Ghasemzadeh, Ali, Nasiri, Alireza, Jaafar, Hawa Z. E., Baghdadi, Ali, Ahmad, Izham“…Extracts of 6-month-old bud exhibited a significant in vitro anticancer activity against HeLa cancer cells with IC(50) value of 56.8 µg/mL. …”
Publicado 2014
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8296por Konopka, Krystyna, Spain, Christopher, Yen, Allison, Overlid, Nathan, Gebremedhin, Senait, Düzgüneş, Nejat“…We also examined whether there is a correlation between the survivin promoter-driven expression of luciferase and the level of endogenous survivin. Human cancer cells (HeLa, KB, HSC-3, H357, H376, H413), oral keratinocytes, GMSM-K, and chemically immortalized human mammary cells, 184A-1, were transfected with Metafectene at 2 μl/1 μg DNA. …”
Publicado 2008
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8297“…HOXC6 expression was analyzed in six CC cell lines (C-33A, HeLa, CaSki, SiHa, ME-180, and HCC-94) by reverse transcription quantitative polymerase chain reaction (RT-qPCR) and western blot analysis. …”
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8298por Kruppa, Michael D., Jacobs, Jeremy, King-Hook, Kelsey, Galloway, Keleigh, Berry, Amy, Kintner, Jennifer, Whittimore, Judy D., Fritz, Rolf, Schoborg, Robert V., Hall, Jennifer V.“…Likewise, pre-incubation of EB with laminarin, a soluble preparation of β-glucan, alone or in combination with other fungal cell wall components significantly decreases chlamydial infectivity in HeLa cells. These data indicate that interactions between EB and C. albicans inhibit chlamydial infectivity, possibly by physically blocking EB interactions with host cell receptors.…”
Publicado 2019
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8299por Kim, Albert, Zhou, Jiawei, Samaddar, Shayak, Song, Seung Hyun, Elzey, Bennet D., Thompson, David H., Ziaie, Babak“…In vitro tests show that HeLa cells irradiated with μLights undergo a 70% decrease in average cell viability as compared to the control group. …”
Publicado 2019
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8300por Denis, Jean-François, Diagbouga, Mannekomba R., Molica, Filippo, Hautefort, Aurélie, Linnerz, Tanja, Watanabe, Masakatsu, Lemeille, Sylvain, Bertrand, Julien Y., Kwak, Brenda R.“…Transfection of communication-incompetent HeLa cells with Cx40 demonstrated that the regulation of proliferation by Cx40 was not limited to ECs. …”
Publicado 2019
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