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841por Tsai, Jie-Heng, Hsu, Li-Sung, Huang, Hsiu-Chen, Lin, Chih-Li, Pan, Min-Hsiung, Hong, Hui-Mei, Chen, Wei-Jen“…Herein, we found that HMDB dose- and time-dependently inhibited growth of HeLa cervical cancer cells, accompanied with G1 cell cycle arrest. …”
Publicado 2016
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842por Santos, P. A. S. R., Avanço, G. B., Nerilo, S. B., Marcelino, R. I. A., Janeiro, V., Valadares, M. C., Machinski, Miguel“…CEO and GEO exhibited potent cytotoxic activity against HeLa cells. IC(50) obtained was 36.6 μg/mL for CEO and 129.9 μg/mL for GEO. …”
Publicado 2016
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843“…Finally, an immunoprecipitation assay revealed a direct physical interaction between Herc5 and β-catenin in HeLa cells. In conclusion, these data suggest that CYP1B1 may activate Wnt/β-catenin signaling through stabilization of β-catenin protein from Herc5-mediated ISGylation for proteosomal degradation.…”
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844por Akaboshi, Mitsuhiko, Kawai, Kenichi, Kinashi, Yuko, Masunaga, Shinichiro, Ono, Koji“…HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled cis‐diamine(glycolato)platinum(II) (254‐S) under various conditions, and the relationship between the lethal effect and the numbers of Pt atoms binding to DNA, RNA, and proteins was examined. …”
Publicado 1996
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845por Contis-Montes de Oca, Arturo, Rodarte-Valle, Estefanía, Rosales-Hernández, Martha Cecilia, Abarca-Rojano, Edgar, Rojas-Hernández, Saúl, Fragoso-Vázquez, Manuel Jonathan, Mendieta-Wejebe, Jessica Elena, Correa-Basurto, Ana María, Vázquez-Moctezuma, Ismael, Correa-Basurto, José“…N-(2′-Hydroxyphenyl)-2-propylpentanamide (OH-VPA) is a valproic acid (VPA) derivative with improved antiproliferative activity toward breast cancer (MCF-7, MDA-MB-231, and SKBr3) and human cervical cancer cell lines (HeLa) compared to that of VPA. However, the pharmacological mechanism of OH-VPA activity remains unknown. …”
Publicado 2018
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846por Ichikawa, Ryoko, Kawasaki, Rie, Iwata, Aya, Otani, Sayaka, Nishio, Eiji, Nomura, Hiroyuki, Fujii, Takuma“…Here, we investigated the effects of enforced miR-126-3p expression in the cervical cancer cell line, HeLa, on proliferation, migration, invasion, apoptosis and protein expression. …”
Publicado 2020
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847por Sargazi, Saman, Moudi, Mahdiyeh, Kooshkaki, Omid, Mirinejad, Shekoufeh, Saravani, Ramin“…Caspase-3 expression was increased in the HeLa cells after 6 and 12 hours (P<0.001) whereas γ-H2AX levels significantly increased after 24 and 48 hours of treatment (P<0.001). …”
Publicado 2020
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848“…In this study, we have investigated the effect of inhibition of LDH-A on cells viability and identifying the mechanism of cell death in HeLa and MCF-7 cancer cells. Human cervical cancer HeLa cell line and breast cancer MCF-7 cell line were used to investigate the effect of inhibition of LDH-A by sodium oxamate on cell survival and proliferation using western blot, spectrophotometry, and immunofluorescent study. …”
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849por Sai, Chunmei, Qin, Wei, Meng, Junyu, Gao, Li-Na, Huang, Lufen, Zhang, Zhen, Wang, Huannan, Chen, Haixia, Yan, Chaohua“…Further, the Wnt/β-catenin signaling cascade activation in MA-treated HeLa cells was attenuated in a dose-dependent manner. …”
Publicado 2021
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850por Zhang, Jing, Wei, Xuan, Wang, Yuanhang, Ren, Bo, Zhao, Litao, Wang, Zhaoyan, Pu, Qiaosheng“…In this work a rapid, sensitive, and practical method was developed for the determination of Na(+) and K(+) concentration in HeLa cells during emodin induced apoptosis by a low-cost capillary electrophoresis device with capacitively coupled contactless conductivity detection (CE-C(4)D). …”
Publicado 2018
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851“…Doubling time assay was used to observed HeLa cells proliferation. RESULTS: The IC(50) of soluble ethyl acetate partition of this plant was 82.41± 6.73 µg/ml against HeLa cells. …”
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852por Lv, Dian, Lai, Qi, Zhang, Qi, Wang, Ji-hong, Li, Yuan-ce, Zeng, Guang-Zhi, Yin, Jun-Lin“…In conclusion, 3-DSC inhibited the proliferation, migration and invasion of HeLa and PC3 cells.…”
Publicado 2022
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854por Horta, Bruno, Freitas-Silva, Joana, Silva, Jani, Dias, Francisca, Teixeira, Ana Luísa, Medeiros, Rui, Cidade, Honorina, Pinto, Madalena, Cerqueira, Fátima“…In this work, the effect of chalcones 1–18 against the metabolic viability of cervical (HeLa) and prostate (PC-3 and LNCaP) tumor cell lines was tested, to compare the activity against solid and liquid tumor cells. …”
Publicado 2023
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855por Zhang, Zhewen, Yi, Juan, Xie, Bei, Chen, Jing, Zhang, Xueyan, Wang, Li, Wang, Jingyu, Hou, Jinxia, Wei, HulaiEnlace del recurso
Publicado 2023
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856por Liu, Yiyao, Zhao, Fenglong, Gu, Wentian, Yang, Haishiu, Meng, Quoquan, Zhang, Yunxiang, Yang, Hong, Duan, Qi“…HeLa cell migration and invasion were studied by using Millicell cell culture insert system. …”
Publicado 2009
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857por Popovic, Jelena, Stanisavljevic, Danijela, Schwirtlich, Marija, Klajn, Andrijana, Marjanovic, Jelena, Stevanovic, Milena“…The ectopic expression of SOX14 was demonstrated at the mRNA level in NT2/D1, P19 and HeLa cells, while an increased level of SOX14 protein was detected in HeLa cells only. …”
Publicado 2014
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858“…Here, we investigated whether NO-mediated VEGF expression could be regulated by Tβ4 expression in HeLa cervical cancer cells. Hypoxia inducible NO production and VEGF expression were reduced by small interference (si) RNA of Tβ4. …”
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859por Abu, Nadiah, Yeap, Swee K., Pauzi, Ahmad Z. Mat, Akhtar, M. Nadeem, Zamberi, Nur R., Ismail, Jamil, Zareen, Seema, Alitheen, Noorjahan B.“…Collectively, Isopimara-7,15-Dien-19-Oic Acid managed to induce cellular stress in HeLa cells and activate several anti- and pro survival pathways.…”
Publicado 2016
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860“…Herein is a first effort to study effect of carbon-sulfur (C-S) and carbon-nitrogen (C-N) bonds modification on the antitumor activity of the podophyllum derivatives in HeLa cells. Compared with the derivative modified by the C-N bond, the C-S bond modification exhibited superior antitumor activity by further causing significant mitochondria depolarization from three signaling pathway. …”
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