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1201por Khazaei, Somayeh, Esa, Norhaizan M., Ramachandran, Vasudevan, Hamid, Roslida A., Pandurangan, Ashok K., Etemad, Ali, Ismail, Patimah“…The multiple therapeutic effects of natural compounds in traditional medicine motivate us to evaluate the cytotoxic activity of bulb of Allium atroviolaceum in MCF7 and MDA-MB-231, HeLa and HepG2 cell lines. The bulb methanol extract of A. atroviolaceum was found to be an active cell proliferation inhibitor at the time and dose dependent manner. …”
Publicado 2017
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1202“…These events might enhance resistance to apoptosis and promote cytoprotective autophagy in HeLa and CaSki cells. The present study is the first to uncover a key prosurvival modulator, Yip1A, which coordinates IRE1 signaling with PERK signaling to support the survival of HeLa and CaSki cervical cancer cells.…”
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1203“…In-vitro assays revealed that ectopic miR-let-7a expression repressed SiHa and HeLa cell proliferation, migration and invasion, and enhanced SiHa and HeLa cell apoptosis. …”
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1204por Ali, Akhtar, Kim, Sung Hwan, Kim, Min Jun, Choi, Mee Young, Kang, Sang Soo, Cho, Gyeong Jae, Kim, Yoon Sook, Choi, Jun-Young, Choi, Wan Sung“…Inhibition of O-GlcNAcylation by 6-Diazo-5-oxo-L-norleucine (DON) treatment decreased p65 activation, eventually inhibiting CXCR4 expression in HeLa cells. Lung tissues from mice engrafted with OGT-knockdown HeLa cells (shOGT) exhibited lower expression of Ki-67 and HPV E6 and E7 oncogenes compared to lung tissues from mice engrafted with control HeLa cells (shCTL). …”
Publicado 2017
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1205“…HIPK1-AS expression levels were upregulated in response to HeLa CM, but were decreased under SPS treatment. …”
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1206“…Furthermore, BRCC3 expression levels were enhanced in HeLa, SiHa and C-33A cervical cancer cells. BRCC3 interference in HeLa and SiHa cells was revealed to suppress cell viability, invasion and migration abilities via upregulation of E-cadherin expression levels and downregulation of Vimentin, matrix metalloproteinase (MMP)-2, MMP-9, snail family transcriptional repressor (Snai)1 and Snai2 expression levels. …”
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1207por Shi, Xi, Qiu, Shiwei, Zhuang, Wei, Wang, Caiji, Zhang, Shili, Yuan, Na, Yuan, Fukang, Qiao, Yuehua“…MATERIALS AND METHODS: An in vivo experiment using nude mice injected with HeLa cells was performed. Flow cytometry, western blotting, and real-time quantitative PCR analyses were done. …”
Publicado 2018
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1208por Phatvej, Wipaporn, Datta, Harish K., Wilkinson, Simon C., Mutch, Elaine, Daly, Ann K., Horrocks, Benjamin R.“…The liver cell lines (HepG2 and Huh7) were the most active and HeLa and CACO-2 showed comparable activity. Previous work has reported a cholesterol-sensitivity of the endocytosis (HeLa), which suggests a caveolin-mediated pathway. …”
Publicado 2019
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1209por Yan, Wei, Yang, Jianhong, Tang, Huan, Xue, Linlin, Chen, Kai, Wang, Lun, Zhao, Min, Tang, Minghai, Peng, Aihua, Long, Chaofeng, Chen, Xiaoxin, Ye, Haoyu, Chen, Lijuan“…Preliminary activity screening with HeLa and MCF-7 cells showed that ten compounds (3–5, 9, 12, 17–19, 24, and 25) had potential cytotoxicity. …”
Publicado 2019
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1210por Han, Kyu-Hyun, Kim, Ae-Kyeong, Jeong, Gun-Jae, Jeon, Hye Ran, Bhang, Suk Ho, Kim, Dong-ik“…CONCLUSIONS: H-CM showed enhanced anti-cancer effects on HeLa cells but did not influence cell viability or apoptosis of hDFs and these different effects were supported by profiling of secretory proteins in both kinds of CM and intracellular signaling of HeLa cells and hDFs.…”
Publicado 2019
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1211por Kim, Min Young, Kim, Yoon Sook, Kim, Minjun, Choi, Mee Young, Roh, Gu Seob, Lee, Dong Hoon, Kim, Hyun Joon, Kang, Sang Soo, Cho, Gyeong Jae, Shin, Jeong Kyu, Choi, Wan Sung“…Of note, we found that metformin treatment of HeLa cells increased the levels of p21 and p27 (which are AMPK-dependent cell cycle inhibitors), leading to increased cell cycle arrest and apoptosis in HeLa cells compared to untreated cells. …”
Publicado 2019
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1212“…METHODS: After the cervical cancer cells (HeLa cells, CaSki cells) had been cultured, cisplatin and genistein were added to the culture medium, and the cell activity was measured using MTT assay. …”
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1213por Johansson, Karl E., Ståhl, Anne-Lie, Arvidsson, Ida, Loos, Sebastian, Tontanahal, Ashmita, Rebetz, Johan, Chromek, Milan, Kristoffersson, Ann-Charlotte, Johannes, Ludger, Karpman, Diana“…Stx induced ATP release from HeLa cells and in a mouse model. Toxin induced rapid calcium influx into HeLa cells, as well as platelets, and a P2X1 receptor antagonist, NF449, abolished this effect. …”
Publicado 2019
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1214“…A HeLa xenograft mouse model was established to determine the effect of ADSCs on tumor growth in vivo. …”
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1215por Zhao, Yali, Iyer, Shankar, Tavanaei, Maryam, Nguyen, Nicole T., Lin, Andrew, Nguyen, Thao P.“…In NRVM-NRVM and NRVM-HeLa controls, no arrhythmias occurred under either experimental condition. …”
Publicado 2021
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1216por Feng, Shini, Ren, Yajing, Li, Hui, Tang, Yunfei, Yan, Jinyu, Shen, Zeyuan, Zhang, Huijie, Chen, Fuxue“…METHODS: Cell membrane extracted from HeLa cells (HM) was used to encapsulate BNs by physical extrusion. …”
Publicado 2021
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1217“…Re-expression of LDHA in LDHA-knockout HeLa cells partially restored hydrogen peroxide production. …”
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1218“…Results from wound healing and Transwell assays further demonstrated the inhibitory effect of ALW-II-41-27 on CaSki and HeLa cell migration and invasion, respectively. Furthermore, ALW-II-41-27 inhibited the protein expression of GTP-RhoA and ROCK1 in CaSki and HeLa cells. …”
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1219por Pakniyat, Fatemeh, Nedaie, Hassan Ali, Mozdarani, Hossein, Mahmoudzadeh, Aziz, Gholami, Somayeh“…This finding was confirmed with “2 Gy apoptosis enhancement ratio” which was 1.77 and 1.42 in HeLa and HN5. The increased levels of DNA DSBs were observed after irradiation; significant in HeLa with enhancement rate of 19.24. …”
Publicado 2022
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1220“…DNA damage was quantified with γH2AX foci analysis and the response of CaSki and HeLa cells to irradiation was determined using a colony formation assay. …”
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