“…In myogenic cells, but not in HeLa, Grp94 overexpression exerted cytoprotection by reducing ER Ca(2+) storage, due to an inhibitory effect on SERCA2. …”
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“…The interactions between the two types of biomimetic micro-PDMS surfaces and two kinds of human cervical cancer cells (HeLa and SiHa) were investigated. HeLa and SiHa cells cultured on the two micropatterned PDMS samples exhibited more stretchable morphology, higher diffusion, and a much lower nuclear/cytoplasmic ratio than those cultured on flat PDMS surfaces, indicating a higher adhesion area of the cells. …”
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“…These bore the substituents p-toluidino (3d), p-ethylanilino (3h) and 3′,4′-dimethylanilino (3f), and these compounds had IC(50) values of 30–43, 160–240 and 67–160 nM, respectively, on HeLa, A549 and HT-29 cancer cells. The p-toluidino derivative 3d was the most potent inhibitor of tubulin polymerization (IC(50): 0.45 µM) and strongly inhibited the binding of colchicine to tubulin (72% inhibition), with antiproliferative activity superior to CA-4 against A549 and HeLa cancer cell lines. …”
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“…As compared to HeLa, there is a reduced co-localization of AKTIP with lamin A/C in both MCF7 and A549. …”
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“…Intracellular levels of ATP, GTP, and hexose phosphates have been determined in HeLa cells at intervals after exposure to saturating doses of diphtheria toxin. …”
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“…Several dietary phytochemicals have been reported to have growth inhibitory and apoptotic effect on HeLa and other cervical cell lines. In this study, using Hoechst 33342 staining, MTT, Annexin V-FLUOS/PI and TUNEL assays we demonstrated that Syzygium cumini extract inhibits the growth and induces apoptosis in HeLa and SiHa cervical cancer cell lines in a dose- and time-dependent manner. …”
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“…Up to 69% of HeLa and 65% of KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg/mL).…”
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“…In particular; 1f and 2i exhibited potent cytotoxic activities against HeLa cells and BGC823 cells with better IC(50) values than gefitinib.…”
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“…The complexes decrease the viability of both “easy-to-transfect” cells (HeLa) and “hard-to transfect” ones (HL-60), indicating a high potential of the cationic carbosilane dendrimers for siRNA delivery into tumor cells.…”
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“…The phages specifically inhibited IBV infectivity in HeLa cells and blocked IBV haemagglutination. One linear peptide “GSH HRH VHS PFV” from the positive phages with the highest neutralization titer was synthesized and this peptide inhibited IBV infection in HeLa as well. …”
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“…These newly synthesized compounds were found to be cytotoxic in human epithelioid cervix carcinoma (HeLa) and human colon cancer cell lines (Caco-2). …”
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“…The prepared Aβ40-C(60) exhibits photo-induced activity with visible light to induce the inhibition of Aβ40 fibrillation and the cytotoxicity for cultured HeLa cells. The observed photo-induced phenomena result from the generation of singlet oxygen via photoexcitation, inducing oxidative damage to Aβ40 and HeLa cells. …”
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“…RESULTS: The expression of miR-19-3p in cervical cancer tissues and SiHa and HeLa cells was significantly upregulated, whereas the expression of PTEN was significantly downregulated. …”
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“…Cellular uptake studies were carried out with HeLa cells incubated with β-ionone liposomes for two hours. …”
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“…In addition, the increase in the subG1 fraction was observed in PC-3 and HeLa cells. The application of a fluorescent H(2)DCFDA probe revealed the high pro-oxidative properties of the tested triazine derivatives, especially MM131. …”
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“…In this study, we report the synthesis of GRO-NLs and their in vitro anticancer potential in breast (MCF-7), colon (HT-29), and cervical (HeLa) cancer cells. GRO-NLs-treated HT-29, HeLa, and MCF-7 cells showed cytotoxicity in the MTT and NRU assays via defects in mitochondrial functions and lysosomal activity. …”
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“…The IC(50) value of quercetin loaded PEGylated liposomes was 16.3 μg/mL on HeLa cells, while that of quercetin was 88.3 μg/mL. …”
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“…Among all drug combinations, the carvacrol nanoparticles with the doxorubicin combination group exerted greater dose-dependent growth inhibition of both MCF-7 and HeLa cells as compared to single carvacrol nanoparticles and doxorubicin. …”
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“…These endocytic fusion events are likely culminating in productive infection since endocytic inhibitors, such as EIPA, Pitstop2, and Dynasore, as well as a dominant-negative dynamin-2 mutant, inhibited HIV-1 infection in HeLa-derived and primary CD4+ T-cells. Furthermore, the inhibition of endocytosis in HeLa-derived cells promoted hemifusion at the PM but abrogated complete fusion. …”
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“…In contrast, in Ishikawa cells, having basal proline oxidase level significantly higher than HeLa cells, santin treatment decreased its expression. …”
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