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  1. 1641
    “…Free MMC was toxic to both cancer and normal cells. Apoptosis of the HeLa, SiHa, and PC9 cells was higher than that of the A549 cells; however, the apoptotic effect on 16HBE cells was minimal. …”
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    Antitumor Activity of a Novel Double-Targeted System for Folate Receptor-Mediated Delivery of Mitomycin C
  2. 1642
    “…Co-delivery of POSS and anthracyclines led to higher anti-cancer activity towards HeLa (cervical cancer endothelial) and MCF-7 (human breast adenocarcinoma) cell lines. …”
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    Hydrophilic Polyhedral Oligomeric Silsesquioxane, POSS(OH)(32), as a Complexing Nanocarrier for Doxorubicin and Daunorubicin
  3. 1643
    “…Gene expression analysis shows that TriCurin activates pro-apoptotic genes and represses anti-apoptotic genes in HeLa cells. TriCurin in a microemulsion is stable and non-toxic to cervical tissue. …”
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    A novel cancer preventative botanical mixture, TriCurin, inhibits viral transcripts and the growth of W12 cervical cells harbouring extrachromosomal or integrated HPV16 DNA
  4. 1644
    “…Compound 3 showed potent cytotoxic effects against MCF-7, HepG2, and HeLa with IC(50) values = 2.4 ± 0.20, 3.1 ± 0.10 and 0.9 ± 0.05 μg/mL, respectively. …”
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    Antiproliferative Isoprenoid Derivatives from the Red Sea Alcyonacean Xenia umbellata
  5. 1645
    “…Compared with those of wild-type POR-1 and CΔvscF, the cytotoxic, adherent, and apoptotic abilities of ΔvscF in HeLa cells were significantly reduced (P < 0.01). …”
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    VscF in T3SS1 Helps to Translocate VPA0226 in Vibrio parahaemolyticus
  6. 1646
    “…RESULTS: Metabolic substrates were utilised in Panc-1 and HeLa but not in OVCAR3 and SK-MEL-28 cells following plasma treatment. …”
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    The amino acid metabolism is essential for evading physical plasma-induced tumour cell death
  7. 1647
    “…We constructed xenograft models using cervical cancer (HeLa) and uterine endometrial cancer (HEC1B) cell lines. …”
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    Enhanced antitumor activity of combined lipid bubble ultrasound and anticancer drugs in gynecological cervical cancers
  8. 1648
    “…All the isolated endophytic fungal extracts were tested for their cytotoxicity against HeLa and A431 cancer cell lines. Nine isolates were further analyzed for their cytotoxic activity from the culture filtrate and mycelia extract. …”
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    Diversity of Marine Macro-Algicolous Endophytic Fungi and Cytotoxic Potential of Biscogniauxia petrensis Metabolites Against Cancer Cell Lines
  9. 1649
    “…Our data demonstrated that IR might cause autophagy of both MCF-7 and HeLa cells, which is related to mitochondria and mROS, and the ROS scavenger N-acetylcysteine (NAC) could reduce the effects. …”
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    Pink1/PARK2/mROS-Dependent Mitophagy Initiates the Sensitization of Cancer Cells to Radiation
  10. 1650
    “…Also, it was observed that the extracts do not possess cytotoxic activity against different cell lines, where E. cardamomum showed EC(50) (µg/mL) of 473.84 (HeLa cells), 237.36 (J774A.1 cells), 257.51 (Vero E6 cells), and 431.16 (Balb/C peritoneal cells) and C. longa showed EC(50) (µg/mL) of 351.17 (HeLa cells), 430.96 (J774A.1 cells), 396.24 (Vero E6 cells), and 362.86 (Balb/C peritoneal cells). …”
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    Benefits of Cardamom (Elettaria cardamomum (L.) Maton) and Turmeric (Curcuma longa L.) Extracts for Their Applications as Natural Anti-Inflammatory Adjuvants
  11. 1651
    “…The compounds 3a–3c showed a strong induction of apoptosis in HeLa and G-361 cells after 24 h.…”
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    Novel Oleanolic Acid-Tryptamine and -Fluorotryptamine Amides: From Adaptogens to Agents Targeting In Vitro Cell Apoptosis
  12. 1652
    “…MATERIALS AND METHODS: MCF-7 and HeLa cells were treated with and without 0.5 μMol/L of Bi(2)O(3)-NR of varying sizes (60, 70, 80, and 90 nm). …”
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    Radiosensitization effects by bismuth oxide nanorods of different sizes in megavoltage external beam radiotherapy
  13. 1653
    “…Results: Here, we show that endogenous ARF expression in HeLa cells is required for starvation-induced autophagy. …”
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    Mutation of the Conserved Threonine 8 within the Human ARF Tumour Suppressor Protein Regulates Autophagy
  14. 1654
    “…Protein kinase signaling by Stx and its A and B subunits was induced by PKA, PKG, and PKC in HeLa cells. CaM kinase induction was significant in Vero cells. …”
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    Protein Kinase Signaling by Shiga Toxin Subunits
  15. 1655
    “…Ectopically expressed RASA4 weakened the proliferative potential of HeLa cells, whereas RASA4 genetic inactivation produced the opposite impact in the HeLa and C-33A cells. …”
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    RASA4 inhibits the HIFα signaling pathway to suppress proliferation of cervical cancer cells
  16. 1656
    “…M3-HBx and Ct-HBx significantly upregulated the expression of PAI1 and CDC20 in HepG2 and HeLa cells as well as the livers of SB mice. Silencing PAI1 attenuated the effects of M3-HBx and Ct-HBx on the growth of HepG2 and HeLa cells. …”
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    The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hepatocellular Carcinoma
  17. 1657
    “…Herein, applying MS proteomics strategy, we revealed PDS significantly downregulated 22 proteins but upregulated 16 proteins in HeLa cancer cells, of which the genes both contain a number of G4 potential sequences, implying that PDS regulation on gene expression is far more complicated than inducing/stabilizing G4 structures. …”
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    G-quadruplex inducer/stabilizer pyridostatin targets SUB1 to promote cytotoxicity of a transplatinum complex
  18. 1658
    “…The EEROP treatment was given to HeLa cells cultured with RPMI medium and incubated at 37°C with 5% CO(2). …”
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    Effect of the Ethanol Extract of Red Okra Pods (Abelmoschus esculentus (L.) Moench) to Inhibit Cervical Cancer Cells Growth through Cell Cycle-Associated Oncogenes
  19. 1659
    “…This study aimed to investigate the beneficial effects of both the fractions and subfractions of adlay seed ethanolic extract on the human breast (MCF-7) and cervical (HeLa) cancer cell lines, as well as exploring their possible mechanisms of action. …”
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    Adlay Seed (Coix lacryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract Fractions and Subfractions Induce Cell Cycle Arrest and Apoptosis in Human Breast and Cervical Cancer Cell Lines
  20. 1660
    “…These results indicate that SalB activates Akt/PKB signaling and inhibits apoptosis in infected HeLa cells. Taken together, these results suggest that SalB could be used to develop a new therapeutic drug for EV71-induced HFMD.…”
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    Salvianolic Acid B Inhibits Hand-Foot-Mouth Disease Enterovirus 71 Replication through Enhancement of AKT Signaling Pathway
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