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1721por Zhao, Menghui, Cui, Yaxin, Zhao, Lang, Zhu, Tianyu, Lee, Robert J., Liao, Weiwei, Sun, Fengying, Li, Youxin, Teng, Lesheng“…Their cytotoxicity was assessed against HeLa and Hep G2 cells. Compound 480 was identified as a promising candidate because of its low IC(50) in HeLa (12.61 μg/mL) and Hep G2 (33.42 μg/mL) cells. …”
Publicado 2019
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1722“…MTT assay indicated that five screened hits suppressed the growth of HeLa cells. Particularly, hit-5, as a selective PLK1 inhibitor targeting PLK1-PBD, significantly inhibited the progression of HeLa cells-derived xenograft, with no obvious side effects. …”
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1723“…Compound 6 showed modest cytotoxicity against the HeLa cell line with an IC(50) value of 35.2 μM. Compound 9 also showed cytotoxic to the HeLa and MCF-7 cell lines, with IC(50) values of 60.8 and 22.6 μM, respectively. …”
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1724por Sharma, Sudhir Kumar, Vijay, Sauparnika, Gore, Sangram, Dore, Timothy M., Jagannathan, Ramesh“…A noninvasive magnetoencephalography (MEG) technique was used to measure the magnetic field emanating from HeLa, HEK293, and H9c2(2-1) rat cardiac cells. The addition of a nonlethal dose of ionomycin to HeLa and capsaicin to TRPV1-expressing HEK293 cells resulted in a sudden change in the magnetic field signal consistent with Ca(2+) influx, which was also observed by confocal fluorescence microscopy under the same conditions. …”
Publicado 2020
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1725por Joshi, Pusp Raj, Paudel, Mukti Ram, Chand, Mukesh Babu, Pradhan, Shreeti, Pant, Krishna Kumar, Joshi, Giri Prasad, Bohara, Manoj, Wagner, Sven H., Pant, Basant, Pant, Bijaya“…The extracts of orchid species were screened for cytotoxic effect on the human cervical cancer cells (HeLa) and human glioblastoma cells (U251) using an MTT assay. …”
Publicado 2020
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1726por Studzian, Maciej, Działak, Paula, Pułaski, Łukasz, Hedstrand, David M., Tomalia, Donald A., Klajnert-Maculewicz, Barbara“…Quite surprisingly, transfection activity could not be demonstrated in HeLa cells, and the possible reasons are discussed in the article.…”
Publicado 2020
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1727“…Furthermore, the low cysteine levels in living single HeLa cells could be monitored, in the presence of cystine transporter inhibitor. …”
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1728por Kebbi, Sara, Ciavatta, Maria Letizia, Mahmoud, Ali Mokhtar, Carbone, Marianna, Ligresti, Alessia, Seghiri, Ramdane, Gavagnin, Margherita“…The effect of new compounds 1 and 2 and inuviscolide (3) on HeLa cell has also been evaluated.…”
Publicado 2021
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1729por Sanchez-Martos, Miguel, Martinez-Navarrete, Gema, Bernabeu-Zornoza, Adela, Humphreys, Lawrence, Fernandez, Eduardo“…We tested and compared its transfection effectiveness in vitro as a vehicle for the EGFP plasmid DNA (pDNA) reporter in the SH-SY5Y human neuroblastoma, HeLa, and 3T3 cell lines. Using fluorescent microscopy and flow cytometry, we demonstrated high transfection efficiencies based on EGFP fluorescence in SH-SY5Y cells, compared with HeLa and 3T3. …”
Publicado 2021
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1730“…Maximum cell viability in HeLa and HepG2 tumor cell lines was observed.…”
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1731por Wu, Zhong-Nan, Niu, Qian-Wen, Zhang, Yu-Bo, Luo, Ding, Li, Qing-Guo, Li, Ying-Ying, Kuang, Guang-Kai, He, Li-Jun, Wang, Guo-Cai, Li, Yao-Lan“…All compounds were tested for their cytotoxic activities on human HepG-2, HeLa, MCF-7, and A549 cell lines via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
Publicado 2019
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1732por Wang, Yi, Cui, Qiyao, Zhao, Xiaoshuang, Qin, Tang, Wang, Wenjing, Sun, Hongmei, Zhu, Hongda, Guo, Huiling, Sun, Honghao“…In addition, cellular uptake of GSDCH by HeLa cells can be achieved effectively with the help of hyaluronic acid (HA). …”
Publicado 2018
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1733“…We characterize two new PRL-HeLa cell models expressing either inducible C-terminal (iGFP-ER) or N-terminal (iER-GFP) tagged estrogen receptor-α (ERα) that allows direct visualization of chromatin binding. …”
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1734“…The results indicated that the FITC-labelled CT–HSA was incorporated into HeLa cells in a concentration-dependent manner. The CT–HSA enhanced the binding of anticancer drugs (5-fluorouracil (5-Fu) and mitomycin C (MMC)) comparing with HSA, and the CT–HSA mixed with 5-Fu or MMC decreased significantly the HeLa cell viability as compared with the same concentration of each drug. …”
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1735“…The results indicated that the probe could selectively sense LDs in HeLa cells. Meanwhile, Couoxo-LD can be applied for in vivo imaging of zebrafish.…”
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1736“…We further found that photoblinking rates measured in the live HeLa cells varied as expected with changing excitation power.…”
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1737por Fan, Dongmei, Liu, Pingxian, Jiang, Yunhan, He, Xinlian, Zhang, Lidan, Wang, Lijiao, Yang, Tao“…The representative derivative QW12 exerts a potent antiproliferative effect against HeLa cells (IC(50) value of 10.58 μM), through inducing apoptosis and triggering ROS generation and the accumulation of HeLa cells in vitro. …”
Publicado 2022
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1738por Ikizawa, Takeshi, Ikeda, Kazutaka, Arita, Makoto, Kitajima, Shojiro, Soga, Tomoyoshi, Ichijo, Hidenori, Naguro, Isao“…Here, we found that hyperosmotic stress for a few minutes induces Warburg-like metabolic remodeling in HeLa and Raw264.7 cells and suppresses fatty acid oxidation. …”
Publicado 2022
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1739por Gong, Haiyan, Li, Minghong, Ji, Mengdie, Zhang, Xiaotong, Yuan, Zan, Zhang, Sichen, Yang, Yi, Li, Chun, Chen, Yang“…We applied MINE to investigate the relationship between the SD-RCI and chromatin volume change in HeLa cells before and after liquid-liquid phase separation. …”
Publicado 2023
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1740por Alharthy, Rima D., Rashid, Faisal, Ashraf, Abida, Shafiq, Zahid, Ford, Steven, al-Rashida, Mariya, Yaqub, Muhammad, Iqbal, Jamshed“…Compounds 5j and 5k were found to be most active against HeLa and MCF-7 cells, respectively. G0/G1 cell cycle arrest was observed in treated cancer cells. …”
Publicado 2023
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