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  1. 941
    “…Five out of six individuals showed a reduction in insulin AUC >7237 pmol/l.min, and in two patients this showed a clinically significant cardiovascular benefit (as defined by the Helsinki heart study). CONCLUSIONS: Short-term GR antagonism is sufficient to reduce insulin resistance in some individuals with adrenal incidentalomas and mild cortisol excess. …”
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    Mifepristone Reduces Insulin Resistance in Patient Volunteers with Adrenal Incidentalomas That Secrete Low Levels of Cortisol: A Pilot Study
  2. 942
    “…Our tool, called Traph (Transcrips in gRAPHs), is available at: http://www.cs.helsinki.fi/gsa/traph/.…”
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    A novel min-cost flow method for estimating transcript expression with RNA-Seq
  3. 943
    “…The study received ethics approval from the Coordinating Ethics Committee at Helsinki University Hospital on 8 June 2009 (ref: 4/13/03/00/09).…”
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    Effectiveness of exercise intervention and health promotion on cardiovascular risk factors in middle-aged men: a protocol of a randomized controlled trial
  4. 944
    “…METHODS: The 1803 participants belong to the Helsinki Birth Cohort Study, born 1934–44. Of them, 267 (14.8%) had been evacuated abroad in childhood during WWII and the remaining subjects served as controls. …”
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    Early Life Stress and Physical and Psychosocial Functioning in Late Adulthood
  5. 945
    “…MATERIALS AND METHODS: The study complies with the Declaration of Helsinki and was performed following approval by the ethic committee of the University of Erlangen-Nuremberg. …”
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    X-Ray Induced Formation of γ-H2AX Foci after Full-Field Digital Mammography and Digital Breast-Tomosynthesis
  6. 946
    “…Collection and processing of tissue and peripheral blood samples was performed in compliance with the Declaration of Helsinki. RESULTS: Cancer cell-specific expression of B7-H3 was detected in 19% of clear cell renal cell carcinoma specimens, and tumor vasculature B7-H3 expression was confirmed in 98% (196) of cases. …”
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    B7-H3 is a new cancer-specific endothelial marker in clear cell renal cell carcinoma
  7. 947
    “…ETHICS AND DISSEMINATION: The study was approved by the Danish Data Protection Agency and will be conducted in accordance with the principles of the Helsinki Declaration Representatives from municipalities and clinical practice are engaged in the design and execution of the study in order to ensure the usefulness of survey instruments, reflexive interpretation of data and transfer of implications into practice. …”
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    Readiness for cancer rehabilitation in Denmark: protocol for a cross-sectional mixed methods study
  8. 948
    “…ETHICS AND DISSEMINATION: The study will be performed in agreement with the Declaration of Helsinki and is approved by local ethics committee (NRES Committee London West London: 07/Q0603/76). …”
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    A randomised double-blind control study of early intracoronary autologous bone marrow cell infusion in acute myocardial infarction (REGENERATE-AMI)
  9. 949
    “…All study participants will sign an informed consent to agree to participate in the study, and another consent to agree on the genetic study, in compliance with the Declaration of Helsinki and the WHO standards for observational studies. …”
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    Relationship between target organ damage and blood pressure, retinal vessel calibre, oxidative stress and polymorphisms in VAV-2 and VAV-3 genes in patients with hypertension: a case–control study protocol (LOD-Hipertensión)
  10. 950
    “…All adult patients with STEMI treated by emergency medical services (EMS) in the city of Helsinki from January 2006 to December 2010 were included in the study. …”
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    Ultra-acute increase in blood glucose during prehospital phase is associated with worse short-term and long-term survival in ST-elevation myocardial infarction
  11. 951
    “…METHODS: The study is based on the Helsinki Health Study baseline survey in 2001–2002 and a follow-up in 2007 (N = 4340, response rate 83%) conducted among 40-60-year-old female and male employees. …”
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    The associations between psychosocial working conditions and changes in common mental disorders: a follow-up study
  12. 952
    “…METHODS: Questionnaire survey data collected in 2000-02 among 40–60-year-old employees of the City of Helsinki (N = 8960) were linked with register data on mortality (74% gave permission to the linkage) providing a mean follow-up time of 12-years. …”
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    Leisure-Time Physical Activity and All-Cause Mortality
  13. 953
    “…METHODS: Patients (N = 2342) treated at the Eating Disorder Unit of Helsinki University Central Hospital between 1995 and 2010 were compared with general population controls (N = 9368) matched for age, sex, and place of residence. …”
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    The Increased Risk for Autoimmune Diseases in Patients with Eating Disorders
  14. 954
    “…This study adhered to the principles of the Declaration of Helsinki and guidelines of Good Clinical Practice. …”
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    “Coffee plus Honey” versus “topical steroid” in the treatment of Chemotherapy-induced Oral Mucositis: a randomised controlled trial
  15. 955
    “…ETHICS AND DISSEMINATION: The study was approved by the local institutional review board that works in total compliance with the latest version of the Helsinki Declaration, the Good Clinical Practices (GCP), the ‘America's Document’ and the national regulatory laws. …”
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    Effects of gastric bypass surgery in patients with hypertension: rationale and design for a randomised controlled trial (GATEWAY study)
  16. 956
    “…METHODS: We compared two datasets collected in Helsinki University Central Hospital in 2007–2008 (HUS-STEMI I) and 2011–2012 (HUS-STEMI II), a total of 500 patients treated with primary PCI within 12 hours of the onset of symptoms. …”
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    Trends in treatment delays for patients with acute ST-elevation myocardial infarction treated with primary percutaneous coronary intervention
  17. 957
    “…METHODS: Tumor expression of REG4 was evaluated by immunohistochemistry in 840 consecutive surgically treated CRC patients at Helsinki University Central Hospital. Expression of MUC1, MUC2, MUC5AC, synapthophysin, and chromogranin was evaluated in a subgroup of 220 consecutively operated CRC patients. …”
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    REG4 Independently Predicts Better Prognosis in Non-Mucinous Colorectal Cancer
  18. 958
    “…ETHICS: The study protocol was approved by the Ethics Committee of the University of Dresden (EK 335 122008) based on the Helsinki declaration.…”
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    Cross-cultural adaptation, evaluation and validation of the Spouse Response Inventory: a study protocol
  19. 959
    “…ETHICS AND DISSEMINATION: The study is being carried out in agreement with the Declaration of Helsinki and conducted with the approval of the local medical Ethics Committee (Landesärztekammer Sachsen, Germany, reference number EK-BR-32/13-1) and with the understanding and written consent of each patient's guardian. …”
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    The General Weakness Syndrome Therapy (GymNAST) study: protocol for a cohort study on recovery on walking function
  20. 960
    “…This study was carried out in accordance with the Declaration of Helsinki, after approval by the local National Health Service (NHS) Research Ethics Committee. …”
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    Creatinine and myoglobin are poor predictors of anaerobic threshold in colorectal cancer and health
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